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Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 17 - Number 1




Review Article

Thiol-Activated Anticancer Agents: The State of the Art

, 17(1): 4 - 20

Daniele Dalzoppo, Veronica Di Paolo, Laura Calderan, Gianfranco Pasut, Antonio Rosato, Anna Maria Caccuri and Luigi Quintieri


DOI: 10.2174/1871520616666160817110310



Review Article

Anticancer Drug Combinations, How Far We can Go Through?

, 17(1): 21 - 28

Da-Yong Lu, En-Hong Chen, Hong-Ying Wu, Ting-Ren Lu, Bin Xu and Jian Ding


DOI: 10.2174/1871520616666160404112028



Review Article

Ruthenium(II) Complexes as Potential Apoptosis Inducers in Chemotherapy

, 17(1): 29 - 39

Kangdi Zheng, Qiong Wu, Chengxi Wang, Weijun Tan and Wenjie Mei


DOI: 10.2174/1871520616666160622085441



Review Article

Killing Glioma ‘Stem-like’ Cells via Drug-Induced Relocation of Endosomal Urokinase Proteins

, 17(1): 40 - 47

Fredric A. Gorin, Nagarekha Pasupuleti, Dinesh Mahajan and Sundeep Dugar


DOI: 10.2174/1871520616666160628122901



Research Article

Rapamycin-loaded Immunoliposomes Functionalized with Trastuzumab: A Strategy to Enhance Cytotoxicity to HER2-positive Breast Cancer Cells

, 17(1): 48 - 56

Josimar O. Eloy, Raquel Petrilli, Robert W. Brueggemeier, Juliana Maldonado Marchetti and Robert J. Lee


DOI: 10.2174/1871520616666160526103432



Research Article

Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity

, 17(1): 57 - 66

Livio Racané, Mirela Sedić, Nataša Ilić, Maja Aleksić, Sandra Kraljević Pavelić and Grace Karminski-Zamola


DOI: 10.2174/1871520615666160504094753



Research Article

Design, Synthesis and Evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl Derivatives as Anti-angiogenic Agents Targeting VEGFR-2

, 17(1): 67 - 74

Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and Ramaa Subramanian Chelakara


DOI: 10.2174/1871520615666160504094222



Research Article

Synthesis, in vitro Antiproliferative and Antiinflammatory Activities, and Kinase Inhibitory effects of New 1,3,4-triarylpyrazole Derivatives

, 17(1): 75 - 84

Mohammed I. El-Gamal, Mohammed S. Abdel-Maksoud, Mahmoud M. Gamal El-Din, Ji-Sun Shin, Kyung-Tae Lee, Kyung Ho Yoo and Chang-Hyun Oh


DOI: 10.2174/1871520616666160620074534



Research Article

New 2-Imino-2H-Chromene-3(N-aryl)carboxamides as Potential Cytotoxic Agents

, 17(1): 85 - 92

Rupinder Kaur Gill, Jyoti Kumari and Jitender Bariwal


DOI: 10.2174/1871520616666160310142949



Research Article

Effect of PUFAs Oral Administration on the Amount of Apoptotic Caspases Enzymes in Gastric Cancer Patients Undergoing Chemotherapy

, 17(1): 93 - 101

Homayun Dolatkhah, Ahmad Movahedian, Mohammad-Hossein Somi, Mahmud Aghaei, Naser Samadi, Ahmad Mirza-Aghazade and Ali Esfahani


DOI: 10.2174/1871520616666160520113503



Research Article

Glycodendrimer PPI as a Potential Drug in Chronic Lymphocytic Leukaemia. The Influence of Glycodendrimer on Apoptosis in In Vitro B-CLL Cells Defined by Microarrays

, 17(1): 102 - 114

Ida Franiak-Pietryga, Ewelina Ziółkowska, Barbara Ziemba, Dietmar Appelhans, Henryk Maciejewski, Brigitte Voit, Aleksandra Kaczmarek, Tadeusz Robak, Barbara Klajnert-Maculewicz, Barbara Cebula-Obrzut, Piotr Smolewski, Maciej Borowiec and Maria Bryszewska


DOI: 10.2174/1871520616666160622092947



Research Article

Induction of Autophagic Cell Death in Apoptosis-resistant Pancreatic Cancer Cells using Benzo[α]phenoxazines Derivatives, 10-methyl-benzo[α]phenoxazine-5-one and benzo[α]phenoxazine-5-one

, 17(1): 115 - 125

Sanjima Pal, Sunita Salunke-Gawalib and V. Badireenath Konkimallaa


DOI: 10.2174/1871520616666160624091519



Research Article

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model

, 17(1): 126 - 136

Nuno Mendes, Francisco Tortosa, Andreia Valente, Fernanda Marques, António Matos, Tânia S. Morais, Ana Isabel Tomaz, Fátima Gärtner and M. Helena Garcia


DOI: 10.2174/1871520616666160922165133



Research Article

Synthesis of Icaritin and β-anhydroicaritin Mannich Base Derivatives and Their Cytotoxic Activities on Three Human Cancer Cell Lines

, 17(1): 137 - 142

Van-Son Nguyen, Ling Shi, Sheng-Chun Wang and Qiu-An Wang


DOI: 10.2174/1871520616666160404111210



Research Article

Cordycepin Affects Multiple Apoptotic Pathways to Mediate Hepatocellular Carcinoma Cell Death

, 17(1): 143 - 149

Yulin Zhou, Zhihua Guo, Qingfan Meng, Jiahui Lu, Ning Wang, Hui Liu, Qiming Liang, Yutong Quan, Di Wang and Jing Xie


DOI: 10.2174/1871520616666160526114555




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