Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 14 - Number 8

Editorial

Editorial (Thematic Issue: Emerging Concepts and Therapeutics Strategies for the Treatment of Brain Tumors)

, 14(8): 1063 - 1064

Jianliang Chen and Juan Sebastian Yakisich


DOI: 10.2174/187152061408140908113346




Microenvironment and Brain Tumor Stem Cell Maintenance: Impact of the Niche

, 14(8): 1065 - 1074

Christel Herold-Mende and Andreas Mock


DOI: 10.2174/1871520614666140825103636





Therapeutic Targeting of Malignant Glioma

, 14(8): 1075 - 1084

Daniela Alexandru-Abrams, Martin R. Jadus, Frank P. Hsu, Apostolos Stathopoulos and Daniela A. Bota


DOI: 10.2174/1871520614666140825105145





Overcoming the Blood-Brain Barrier for Chemotherapy: Limitations, Challenges and Rising Problems

, 14(8): 1085 - 1093

Zhaoye Wang, Hui Sun and Juan Sebastian Yakisich


DOI: 10.2174/18715206113139990029





HLA-I Antigen Presentation and Tapasin Influence Immune Responses Against Malignant Brain Tumors-Considerations for Successful Immunotherapy

, 14(8): 1094 - 1100

Anna Darabi, Camilla Thuring and Kajsa M. Paulsson


DOI: 10.2174/1871520614666140825110001





Tapasin and Human Leukocyte Antigen Class I Dysregulation Correlates with Survival in Glioblastoma Multiforme

, 14(8): 1101 - 1109

Camilla Thuring, Linda Geironson and Kajsa Paulsson


DOI: 10.2174/1871520614666140825110402





Translational Gap in Glioma Research

, 14(8): 1110 - 1120

Chi Ma, Gang Zhao, Mabel Hilda Cruz, Ake Siden and Juan Sebastian Yakisich


DOI: 10.2174/1871520614666140825110907





Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski


DOI: 10.2174/1871520614666140418144610





Hecogenin Acetate Inhibits Reactive Oxygen Species Production and Induces Cell Cycle Arrest and Senescence in the A549 Human Lung Cancer Cell Line

, 14(8): 1128 - 1135

Juciano Gasparotto, Nauana Somensi, Alice Kunzler, Carolina Saibro Girardi, Matheus Augusto de Bittencourt Pasquali, Vitor Miranda Ramos, Andre Simoes-Pires, Lucindo Jose Quintans-Junior, Alexsandro Branco, Jose Claudio Fonseca Moreira and Daniel Pens Gelain


DOI: 10.2174/1871520614666140408151751





Baicalin Induces Apoptosis of Gallbladder Carcinoma Cells in vitro via a Mitochondrial-Mediated Pathway and Suppresses Tumor Growth in vivo

, 14(8): 1136 - 1145

Yi-Jun Shu, Run-Fa Bao, Xiang-Song Wu, Hao Weng, Qian Ding, Yang Cao, Mao-Lan Li, Jia-Sheng Mu, Wen-Guang Wu, Qi-Chen Ding, Tian-Yu Liu, Lin Jiang, Yun-Ping Hu, Zhu-Jun Tan, Peng Wang and Ying-Bin Liu


DOI: 10.2174/1871520614666140223191626





Cucurbitacin B Induces DNA Damage, G2/M Phase Arrest, and Apoptosis Mediated by Reactive Oxygen Species (ROS) in Leukemia K562 Cells

, 14(8): 1146 - 1153

Jiajie Guo, Wenwen Zhao, Wenhui Hao, Guowen Ren, Jinjian Lu and Xiuping Chen


DOI: 10.2174/1871520614666140601220915





Modulation of Doxorubicin Mediated Growth Inhibition of Hepatocellular Carcinoma Cells by Platelet Lysates

, 14(8): 1154 - 1160

Maria Grazia Refolo, Rosalba D'Alessandro, Catia Lippolis, Caterina Messa, Nicola Carella, Aldo Cavallini and Brian I. Carr


DOI: 10.2174/1871520614666140604120226





A Steroidal Na+/K+ ATPase Inhibitor Triggers Pro-apoptotic Signaling and Induces Apoptosis in Prostate and Lung Tumor Cells

, 14(8): 1161 - 1168

Sabina Honisch, Saad Alkahtani, Michalis Kounenidakis, Guilai Liu, Saud Alarifi, Hamad Al-Yahya, Konstantinos Dimas, Abdullah A. AlKahtane, Kyriakos C. Prousis, Bader Al-Dahmash, Theodora Calogeropoulou, Konstantinos Alevizopoulos, Florian Lang and Christos Stournaras


DOI: 10.2174/1871520614666140618114418





Differential Role of Apoptosis and Autophagy Associated with Anticancer Effect of Lupulone (Hop β-Acid) Derivatives on Prostate Cancer Cells

, 14(8): 1169 - 1178

Petros X.E. Mouratidis, Kay W. Colston, Nicoletta Charolidi and Grisha Pirianov


DOI: 10.2174/1871520614666140623123006





Dinuclear Berenil-Platinum (II) Complexes as Modulators of Apoptosis in Human MCF-7 and MDA-MB231 Breast Cancer Cells

, 14(8): 1179 - 1186

Gegotek Agnieszka, Ambrozewicz Ewa, Bielawska Anna, Bielawski Krzysztof, Cyunczyk Monika and Skrzydlewska Elzbieta


DOI: 10.2174/1871520614666140623120809





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