Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 14 - Number 6

Editorial

Editorial (Thematic Issue: Phytochemicals, Intracellular Signalling Pathways and Anti-Cancer Effects)

, 14(6): 777 - 778

Jiezhong Chen


DOI: 10.2174/187152061406140612171043




Novel Mechanisms of Anticancer Activities of Green Tea Component Epigallocatechin- 3-Gallate

, 14(6): 779 - 786

Le Zhang, Yaqing Wei and Jinsong Zhang


DOI: 10.2174/1871520614666140521114327




Curcumin: A Promising Agent Targeting Cancer Stem Cells

, 14(6): 787 - 792

Shufei Zang, Tao Liu, Junping Shi and Liang Qiao


DOI: 10.2174/1871520614666140521114735




Garlic-Derived Allyl Sulfides in Cancer Therapy

, 14(6): 793 - 799

Hai-Xia Cao, Ke-Xiang Zhu, Jian-Gao Fan and Liang Qiao


DOI: 10.2174/1871520614666140521120811




The Effect of Lycopene on the PI3K/Akt Signalling Pathway in Prostate Cancer

, 14(6): 800 - 805

Jiezhong Chen, Adam O’Donoghue, Yi-Fu Deng, Bing Zhang, Fanning Kent and Tim O’Hare


DOI: 10.2174/1871520614666140521121317




From French Paradox to Cancer Treatment: Anti-cancer Activities and Mechanisms of Resveratrol

, 14(6): 806 - 825

Xuan Yang, Xun Li and Jinyu Ren


DOI: 10.2174/1871520614666140521121722




Nanoparticle-Delivered Quercetin for Cancer Therapy

, 14(6): 826 - 832

Ke Men, Xingmei Duan, Xia Wei Wei, Ma Ling Gou, Mei Juan Huang, Li Juan Chen, Zhi Yong Qian and Yu Quan Wei


DOI: 10.2174/1871520614666140521122932




Paris polyphylla: Chemical and Biological Prospectives

, 14(6): 833 - 839

Jagmohan S. Negi, Vinod K. Bisht, Arvind K. Bhandari, Vijay P. Bhatt, Pramod Singh and Narayan Singh


DOI: 10.2174/1871520614666140611101040




Research Article

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna


DOI: 10.2174/18715206113136660334




Research Article

Targetability and Biodistribution of Radioiodinated Hypericin: Comparison between Microdosing and Carrier-Added Preparations

, 14(6): 852 - 861

Marlein Miranda Cona, Junjie Li, Yuanbo Feng, Feng Chen, Alfons Verbruggen, Peter de Witte, Raymond Oyen and Yicheng Ni


DOI: 10.2174/18715206113136660360




The Indolylcoumarin COUFIN Exhibits Potent Activity Against Renal Carcinoma Cells without Affecting Hematopoietic System

, 14(6): 862 - 871

Pierre Champelovier, Pascale Barbier, Etienne Daras, Soazig Douillard, Bertrand Toussaint, Virginie Persoon, Veronique Curri, Vincent Peyrot and Sebastien Combes


DOI: 10.2174/1871520614666140223190829




Research Article

Design and Development of Oxazol-5-Ones as Potential Partial PPAR-γ Agonist Against Cancer Cell Lines

, 14(6): 872 - 883

Tanushree Pal, Hardik Joshi and C.S. Ramaa


DOI: 10.2174/1871520614666140528155118




Research Article

miR-1271 Regulates Cisplatin Resistance of Human Gastric Cancer Cell Lines by Targeting IGF1R, IRS1, mTOR, and BCL2

, 14(6): 884 - 891

Mifang Yang, Xia Shan, Xin Zhou, Tianzhu Qiu, Wei Zhu, Yin Ding, Yongqian Shu and Ping Liu


DOI: 10.2174/1871520614666140528161318




Research Article

The Design and Characterization of a Novel beta-casein Nano-vehicle Loaded with Platinum Anticancer Drug for Drug Delivery

, 14(6): 892 - 900

Adeleh Divsalar, Mahdieh Razmi, Ali Akbar Saboury and Arefeh Seyedarabi


DOI: 10.2174/1871520614666140207123147




Research Article

Role of Caspases, Bax and Bcl-2 in Chrysin-Induced Apoptosis in the A549 Human Lung Adenocarcinoma Epithelial Cells

, 14(6): 901 - 909

Saeed Samarghandian, Mohsen Azimi Nezhad and Gholamreza Mohammadi


DOI: 10.2174/1871520614666140209144042




Research Article

Synthesis and Stereochemistry-Activity Relationship of Chiral Thiourea Derivatives as Potential Anticancer Agents

, 14(6): 910 - 920

Vikas Kumar, Akshay Kumar, Vommina V. Sureshbabu and Swapandeep S. Chimni


DOI: 10.2174/18715206113136660368




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