Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 13 - Number 7

Editorial

Editorial (Hot Topic: Inhibition of PI3K/Akt/mTOR Signaling by Natural Products)

, 13(7): 967 - 970

Shile Huang


DOI: 10.2174/1871520611313070001




Targeting the PI3K/Akt/mTOR Axis by Apigenin for Cancer Prevention

, 13(7): 971 - 978

Xin Tong and Jill C. Pelling


DOI: 10.2174/18715206113139990119




Molecular Evidence of Cryptotanshinone for Treatment and Prevention of Human Cancer

, 13(7): 979 - 987

Wenxing Chen, Yin Lu, Guangying Chen and Shile Huang


DOI: 10.2174/18715206113139990115




Hitting the Golden TORget: Curcumin’s Effects on mTOR Signaling

, 13(7): 988 - 994

Christopher S. Beevers, Hongyu Zhou and Shile Huang


DOI: 10.2174/1871520611313070004




Inhibition of Akt/mTOR Signaling by the Dietary Flavonoid Fisetin

, 13(7): 995 - 1001

Deeba N. Syed, Vaqar M. Adhami, Mohammad Imran Khan and Hasan Mukhtar


DOI: 10.2174/18715206113139990129




Targeted Regulation of PI3K/Akt/mTOR/NF-κB Signaling by Indole Compounds and their Derivatives: Mechanistic Details and Biological Implications for Cancer Therapy

, 13(7): 1002 - 1013

Aamir Ahmad, Bernhard Biersack, Yiwei Li, Dejuan Kong, Bin Bao, Rainer Schobert, Subhash B. Padhye and Fazlul H. Sarkar


DOI: 10.2174/18715206113139990078




Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment

, 13(7): 1014 - 1024

Aamir Ahmad, Bernhard Biersack, Yiwei Li, Dejuan Kong, Bin Bao, Rainer Schobert, Subhash B. Padhye and Fazlul H. Sarkar


DOI: 10.2174/18715206113139990117




Inhibition of mTOR Signaling by Quercetin in Cancer Treatment and Prevention

, 13(7): 1025 - 1031

Ansgar Bruning


DOI: 10.2174/18715206113139990114




Targeting mTOR: Evaluating the Therapeutic Potential of Resveratrol for Cancer Treatment

, 13(7): 1032 - 1038

Yan Wu and Feng Liu


DOI: 10.2174/18715206113139990113




Tocotrienols Target PI3K/Akt Signaling in Anti-Breast Cancer Therapy

, 13(7): 1039 - 1047

Paul W. Sylvester and Nehad M. Ayoub


DOI: 10.2174/18715206113139990116




Natural Products Targeting Autophagy via the PI3K/Akt/mTOR Pathway as Anticancer Agents

, 13(7): 1048 - 1056

Hui Sun, Zhaoye Wang and Juan Sebastian Yakisich


DOI: 10.2174/18715206113139990130




From Bacteria to Antineoplastic: Epothilones A Successful History

, 13(7): 1057 - 1068

Samuel Kaiser, Joseane John Muller, Pedro Eduardo Froehlich, Simone Cristina Baggio Gnoatto and Ana Maria Bergold


DOI: 10.2174/18715206113139990133




From Na+/K+-ATPase and Cardiac Glycosides to Cytotoxicity and Cancer Treatment

, 13(7): 1069 - 1087

Petr Babula, Michal Masarik, Vojtech Adam, Ivo Provaznik and Rene Kizek


DOI: 10.2174/18715206113139990304




Suppression of Oncoprotein Her-2 and DNA Damage after Treatment with Flavan-3- ol Vitis labrusca Extract

, 13(7): 1088 - 1095

Gustavo Scola, Claudia Cilene Fernandes Correia Laurino, Eveline Menin and Mirian Salvador


DOI: 10.2174/18715206113139990135




Changes in Glutathione, Oxidative Stress and Mitochondrial Membrane Potential in Apoptosis Involving the Anticancer Activity of Cantharidin Isolated from Redheaded Blister Beetles, Epicauta hirticornis

, 13(7): 1096 - 1114

Akalesh Kumar Verma and Surya Bali Prasad


DOI: 10.2174/18715206113139990131




BIBR 1532 Increases Arsenic Trioxide-mediated Apoptosis in Acute Promyelocytic Leukemia Cells: Therapeutic Potential for APL

, 13(7): 1115 - 1125

Davood Bashash, Seyed H.Ghaffari, Farhad Zaker, Maryam Kazerani, Kebria Hezave, Saeed Hassani, Masomeh Rostami, Kamran Alimoghaddam and Ardeshir Ghavamzadeh


DOI: 10.2174/18715206113139990126




Oncogenic MicroRNA-27a is a Target for Genistein in Ovarian Cancer Cells

, 13(7): 1126 - 1132

Linlin Xu, Jingying Xiang, Jian Shen, Xi Zou, Sulan Zhai, Yongxiang Yin, Ping Li, Xuerong Wang and Qingmin Sun


DOI: 10.2174/18715206113139990006




Synthesis and Antiproliferative Effects of 5,6-Disubstituted Pyridazin-3(2H)-ones Designed as Conformationally Constrained Combretastatin A-4 Analogues

, 13(7): 1133 - 1140

Mohamed Elagawany, Martine Schmitt, Adel Ghiaty, A. Sh. El-Etrawy, Mohamed A. Ibrahim, Frederic Bihel, Aline Borba Sbardelotto, Claudia Pessoa, Tam Luong Nguyen, Ernest Hamel and Jean Jacques Bourguignon


DOI: 10.2174/1871520611313070018




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