Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 13 - Number 4

Editorial (Hot Topic: Survival Signaling Through Focal Adhesion Kinase in Tumors)

, 13(4): 531

Vita M. Golubovskaya


DOI: 10.2174/1871520611313040001




A Small-molecule Inhibitor, 5'-O-Tritylthymidine, Targets FAK and Mdm-2 Interaction, and Blocks Breast and Colon Tumorigenesis in vivo

, 13(4): 532 - 545

Vita M. Golubovskaya, Nadia L. Palma, Min Zheng, Baotran Ho, Andrew Magis, David Ostrov and William G. Cance


DOI: 10.2174/1871520611313040002




Mitoxantrone Targets the ATP-binding Site of FAK, Binds the FAK Kinase Domain and Decreases FAK, Pyk-2, c-Src, and IGF-1R In Vitro Kinase Activities

, 13(4): 546 - 554

Vita M. Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov and William G. Cance


DOI: 10.2174/1871520611313040003




Upregulation of Focal Adhesion Kinase by 14-3-3ε via NFκB Activation in Hepatocellular Carcinoma

, 13(4): 555 - 562

Bor-Sheng Ko, Yee-Jee Jan, Tzu-Ching Chang, Shu-Man Liang, Shyh-Chang Chen, Tzu-An Liu, Yao-Ming Wu, John Wang and Jun-Yang Liou


DOI: 10.2174/1871520611313040004




Cell Survival Signaling in Neuroblastoma

, 13(4): 563 - 575

Michael L. Megison, Lauren A. Gillory and Elizabeth A. Beierle


DOI: 10.2174/1871520611313040005




FAK and Nanog Cross Talk with p53 in Cancer Stem Cells

, 13(4): 576 - 580

Vita M. Golubovskaya


DOI: 10.2174/1871520611313040006




The Role of Focal Adhesion Kinase in Lung Cancer

, 13(4): 581 - 583

Grace K. Dy


DOI: 10.2174/1871520611313040007




FAK and HAS Inhibition Synergistically Decrease Colon Cancer Cell Viability and Affect Expression of Critical Genes

, 13(4): 584 - 594

Melissa Heffler, Vita M. Golubovskaya, Jeffrey Conroy, Song Liu, Dan Wang, William G. Cance and Kelli B. Dunn


DOI: 10.2174/1871520611313040008




Inhibiting the Interaction of cMET and IGF-1R with FAK Effectively Reduces Growth of Pancreatic Cancer Cells in vitro and in vivo

, 13(4): 595 - 602

Deniz A. Ucar, Andrew T. Magis, Di-Hua He, Nicholas J. Lawrence, Said M. Sebti, Elena Kurenova, Maria Zajac-Kaye, Jianliang Zhang and Steven N. Hochwald


DOI: 10.2174/1871520611313040009




Marine Natural Products and Related Compounds as Anticancer Agents: an Overview of their Clinical Status

, 13(4): 603 - 631

Karina Petit and Jean-Francois Biard


DOI: 10.2174/1871520611313040010




Synthesis and Anticancer Properties of a Novel Bis-intercalator

, 13(4): 632 - 638

Wei Shen, Huimin Deng and Zhiqiang Gao


DOI: 10.2174/1871520611313040011




Differential Binding Preference of Methylpheophorbide a and Its Diboronated Derivatives to Albumin and Low Density Lipoproteins

, 13(4): 639 - 646

Galina V. Golovina, Georgy N. Rychkov, Valentina A. Ol’shevskaya, Andrei V. Zaitsev, Valery N. Kalinin, Vladimir A. Kuzmin and Alexander A. Shtil


DOI: 10.2174/1871520611313040012




SJSZ Glycoprotein (38 kDa) Inhibits Cell Cycle and Oxidative Stress in N-Methyl-N`- nitro-N-nitrosoguanidine-induced ICR Mice

, 13(4): 647 - 653

Jin Lee and Kye-Taek Lim


DOI: 10.2174/1871520611313040013




Antitumoral Activity of Indole-3-carbinol Cyclic tri- and Tetrameric Derivatives Mixture in Human Breast Cancer Cells: In Vitro and In Vivo Studies

, 13(4): 654 - 662

Giorgio Brandi, Alessandra Fraternale, Simone Lucarini, Mirko Paiardini, Mauro De Santi, Barbara Cervasi, Maria F. Paoletti, Luca Galluzzi, Andrea Duranti and Mauro Magnani


DOI: 10.2174/1871520611313040014




Recombinant Snake Venom Cystatin Inhibits Tumor Angiogenesis in vitro and in vivo Associated with Downregulation of VEGF-A165, Flt-1 and bFGF

, 13(4): 663 - 671

Qun Xie, Nanhong Tang, Rong Wan, Yuanlin Qi, Xu Lin and Jianyin Lin


DOI: 10.2174/1871520611313040015




N6-Isopentenyladenosine and its Analogue N6-Benzyladenosine Induce Cell Cycle Arrest and Apoptosis in Bladder Carcinoma T24 Cells

, 13(4): 672 - 678

Sara Castiglioni, Silvana Casati, Roberta Ottria, Pierangela Ciuffreda and Jeanette A.M. Maier


DOI: 10.2174/1871520611313040016




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