Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 12 - Number 9

The Nuclear Orphan Receptors NR4A as Therapeutic Target in Cancer Therapy

, 12(9): 1001 - 1014

Alexander J. A. Deutsch, Hannes Angerer, Tamara E. Fuchs and Peter Neumeister


DOI: 10.2174/187152012803529619




Colon Adenocarcinoma Multidrug Resistance Reverted by Euphorbia Diterpenes: Structure-Activity Relationships and Pharmacophore Modeling

, 12(9): 1015 - 1024

Mariana Reis, Ricardo J. Ferreira, Julianna Serly, Noelia Duarte, Ana M. Madureira, Daniel J. V. A. Santos, Joseph Molnar and Maria-Jose U. Ferreira


DOI: 10.2174/187152012803529655




The Role of Peroxisome Proliferator-Activated Receptor-γ in Breast Cancer

, 12(9): 1025 - 1044

Ioly Kotta-Loizou, Constantinos Giaginis and Stamatios Theocharis


DOI: 10.2174/187152012803529664




CCR5 as a Potential Target in Cancer Therapy: Inhibition or Stimulation?

, 12(9): 1045 - 1057

Alicia Gonzalez-Martin, Emilia Mira and Santos Manes


DOI: 10.2174/187152012803529637




Doxorubicin-Loaded Nanoparticles: New Advances in Breast Cancer Therapy

, 12(9): 1058 - 1070

Jose Prados, Consolacion Melguizo, Raul Ortiz, Celia Velez, Pablo J. Alvarez, Jose L. Arias, Maria A. Ruiz, Visitacion Gallardo and Antonia Aranega


DOI: 10.2174/187152012803529646




Anti-metastatic and Anti-angiogenic Properties of Potential New Anti-cancer Drugs Based on Metal Complexes of Selenosemicarbazones

, 12(9): 1071 - 1080

Manja Zec, Tatjana Srdic-Rajic, Aleksandra Konic-Ristic, Tamara Todorovic, Katarina Andjelkovic, Ivana Filipovic-Ljeskovic and Sinisa Radulovic


DOI: 10.2174/187152012803529682




Targeted Therapy for Advanced Urothelial Cancer of the Bladder: Where Do We Stand?

, 12(9): 1081 - 1087

Zhaowei Zhu, Zhoujun Shen and Chen Xu


DOI: 10.2174/187152012803529673




Rational Drug Design for Identifying Novel Multi-target Inhibitors for Hepatocellular Carcinoma

, 12(9): 1088 - 1097

Ahmed Temirak, Mona Abdulla and Mahmoud Elhefnawi


DOI: 10.2174/187152012803529718




JAK2 Inhibitors for Myelofibrosis: Why are They Effective in Patients with and Without JAK2V617F Mutation?

, 12(9): 1098 - 1109

Fabio P. S. Santos and Srdan Verstovsek


DOI: 10.2174/187152012803529727




Anti-cancer Effects of Curcumin on Head and Neck Cancers

, 12(9): 1110 - 1116

Wei Gao, Jimmy Yu-Wai Chan, William Ignance Wei and Thian-Sze Wong


DOI: 10.2174/187152012803529736




Methylenedioxy- and Ethylenedioxy-Fused Indolocarbazoles: Potent Human Topoisomerase I Inhibitors and Antitumor Agents

, 12(9): 1117 - 1131

David E. Zembower, Yongping Xie, Ali Koohang, Mary J. Kuffel, Matthew M. Ames, Yasheen Zhou, Rama Mishra, Aye Aye Mar, Michael T. Flavin and Ze-Qi Xu


DOI: 10.2174/187152012803529628




Dual Roles of Sulforaphane in Cancer Treatment

, 12(9): 1132 - 1142

Tongzhen Xu, Dongmei Ren, Xuefei Sun and Guotao Yang


DOI: 10.2174/187152012803529691




Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules

, 12(9): 1143 - 1155

Michael Hedvat, Luni Emdad, Swadesh K. Das, Keetae Kim, Santanu Dasgupta, Shibu Thomas, Bin Hu, Shan Zhu, Rupesh Dash, Bridget A. Quinn, Regina A. Oyesanya, Timothy P. Kegelman, Upneet K. Sokhi, Siddik Sarkar, Eda Erdogan, Mitchell E. Menezes, Praveen Bhoopathi, Xiang-Yang Wang, Martin G. Pomper, Jun Wei, Bainan Wu, John L. Stebbins, Paul W. Diaz, John C. Reed, Maurizio Pellecchia, Devanand Sarkar and Paul B. Fisher


DOI: 10.2174/187152012803529709




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