Open Access Articles


Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors

, 2017; 17(3): 395 - 403

Chen-Chen Ma and Zhao-Peng Liu





Design, Synthesis and Evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl Derivatives as Anti-angiogenic Agents Targeting VEGFR-2

, 2017; 17(1): 67 - 74

Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and Ramaa Subramanian Chelakara




Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi





The Induction and Repair of DNA Interstrand Crosslinks and Implications in Cancer Chemotherapy

, 2016; 16(2): 221 - 246

Sun Guohui, Zhao Lijiao and Zhong Rugang




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi




Using Cytochalasins to Improve Current Chemotherapeutic Approaches

, 2015; 15(3): 327 - 335

Matthew Trendowski





Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Cytotoxicity and Apoptosis Induced by a Plumbagin Derivative in Estrogen Positive MCF-7 Breast Cancer Cells

, 2014; 14(1): 170 - 180

Sunil Sagar, Luke Esau, Basem Moosa, Niveen M. Khashab, Vladimir B. Bajic and Mandeep Kaur




Differential Effects of Polyphenols on Proliferation and Apoptosis in Human Myeloid and Lymphoid Leukemia Cell Lines

, 2013; 13(10): 1601 - 1613

Amani A Mahbub, Christine L. Le Maitre, Sarah L. Haywood-Small, Gordon J. McDougall, Neil A. Cross and Nicola Jordan-Mahy




The Use of Lentinan for Treating Gastric Cancer

, 2013; 13(5): 681 - 688

Kenji Ina, Takae Kataoka and Takafumi Ando





Are KRAS/BRAF Mutations Potent Prognostic and/or Predictive Biomarkers in Colorectal Cancers?

, 2012; 12(2): 163 - 171

Tomoya Yokota





Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure

, 2010; 10(8): 617 - 624

Yu Toyoda and Toshihisa Ishikawa




New Medical Strategies for Midgut Carcinoids

, 2010; 10(3): 250 - 269

Ola Nilsson, Yvonne Arvidsson, Viktor Johanson, Eva Forssell-Aronsson and Hakan Ahlman




Targeting RSK: An Overview of Small Molecule Inhibitors

, 2008; 8(7): 710 - 716

Tam Luong Nguyen





The Protein Kinase Inhibitor Balanol: Structure – Activity Relationships and Structure-Based Computational Studies

, 2008; 8(6): 638 - 645

Vineet Pande, Maria J. Ramos and Federico Gago





Inhibition of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone Metastases

, 2008; 8(3): 342 - 349

Nadia Rucci, Maria Susa and Anna Teti





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