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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 21, 18 Issues, 2021
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

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Volume 21

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Number 2



Biography   Open Access



Editorial



Review Article (Mini-Review)



Review Article   Open Access



Review Article

A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment

, 21(2): 149 - 161

Ahmed El-Hussein*, Sello L. Manoto, Saturnin Ombinda-Lemboumba, Ziya A. Alrowaili and Patience Mthunzi-Kufa


DOI: 10.2174/1871520620666200403144945


Review Article

Antibody-Based Targeted Interventions for the Diagnosis and Treatment of Skin Cancers

, 21(2): 162 - 186

Suresh Madheswaran, Neelakshi Mungra, Fleury A.N. Biteghe, Jean De la Croix Ndong, Afolake T. Arowolo, Henry A. Adeola, Dharanidharan Ramamurthy, Krupa Naran, Nonhlanhla P. Khumalo and Stefan Barth*


DOI: 10.2174/1871520620666200728123006


Research Article

Botanical Therapeutics (Part II): Antimicrobial and In Vitro Anticancer Activity against MCF7 Human Breast Cancer Cells of Chamomile, Parsley and Celery Alcoholic Extracts

, 21(2): 187 - 200

Corina Danciu, Oana Cioanca, Claudia Watz (Farcaș)*, Monica Hancianu, Roxana Racoviceanu, Delia Muntean, Istvan Zupko, Camelia Oprean, Calin Tatu, Virgil Paunescu, Maria Proks, Zorita Diaconeasa, Codruta Soica, Iulia Pinzaru and Cristina Dehelean


DOI: 10.2174/1871520620666200807213734


Research Article



Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 6


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 21 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

The Efficacy and Safety of Additional Anti-HER2-Targeting Drugs in the Treatment of HER2-Positive Advanced Breast Cancer: A Meta-Analysis


Nannan Du, Bangsheng Chen, Zefeng Shen, Bin Zhou, Xiaojun Fu, Danyi Mao, Feiyan Mao, Derry M. Ng, Parikshit A. Khadaroo and Lei Yang*


DOI: 10.2174/1871520621666201231142841
View Abstract View on PubMed


Alpha-Terpineol as Antitumor Candidate in Pre-Clinical Studies


Helber A. Negreiros, Kariely G. de Moura, Maria L.L.B. do Nascimento, Débora C.N. Rodrigues, Paulo M.P. Ferreira, Débora C. Braz, Marlene G. de Farias, Layde S. Corrêia, Ana R.S. Pereira, Lubna K.B. Santos, Juan C.R. Gonçalves, Anderson N. Mendes, Felipe C.C. da Silva, Ana A.C. Melo-Cavalcante and João M. de Castro e Sousa*


DOI: 10.2174/1871520621999210104195820
View Abstract





Antimutagenic, Antiproliferative and Antioxidant Properties of Sea Grape Leaf Extract Fractions (Coccoloba uvifera L.)


Jorge A. Ramos-Hernández, Montserrat Calderón-Santoyo, Armando Burgos-Hernández, Joel S. García- Romo, Arturo Navarro-Ocaña, María G. Burboa-Zazueta, Edgar Sandoval-Petris and Juan A. Ragazzo- Sánchez*


DOI: 10.2174/1871520621999210104201242
View Abstract


Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug Resistant Human Leukemia Cells


Maiara Bernardes Marques, Ayane Pontes Machado, Priscila Antiqueira Santos, Michele Carrett-Dias, Gabriela Soares Araújo, Barbara da Silva Alves, Bárbara Santos de Oliveira, Flavio M. R. da Silva Júnior, Cristiana Lima Dora, Andrés Delgado Cañedo, Daza M. V. B. Filgueira, Estela Fernandes e Silva* and Ana Paula de Souza Votto


DOI: 10.2174/1871520621999210104200722
View Abstract



99mTechnetium- or Cy7-Labeled Fab(Tocilizumab) as Potential Multiple Myeloma Imaging Agents


Ximena Camacho*, Carolina Perroni, Camila L. Machado, Camila de Godoi Carneiro, Mara de Souza Junqueira, Daniele Faria, María F. García, Marcelo Fernández, Natalia Oddone, Juan Benech, Carlos A. Buchpiguel, Hugo Cerecetto, Roger Chammas, Eloisa Riva, Pablo Cabral and Juan P. Gambini


DOI: 10.2174/1871520621999210104181238
View Abstract


Platelet-Rich and Platelet-Poor Plasma Might Play Supportive Roles in Cancer Cell Culture: A Replacement for Fetal Bovine Serum?


Mehdi Talebi, Mousa Vatanmakanian, Ali Mirzaei, Yaghoub Barfar, Maryam Hemmatzadeh, Milad A. Nahayati, Kobra Velaei, Asghar Hoseinzade, Behruz Yazdanpanah, Yahya Yahyavi, Ako Azimi, Mina Rahmani and Milad Z. Heydarabad*


DOI: 10.2174/1871520621999210101225912
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice


Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives

, 2020; 20(18): 2190 - 2206

Tasnim Zahan, Plabon K. Das, Syeda F. Akter, Rowshanul Habib, Md. Habibur Rahman, Md. Rezaul Karim* and Farhadul Islam*


DOI: 10.2174/1871520620999200730161829









Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity via Tubulin Inhibition

, 2020; 20(12): 1469 - 1474

Lavanya Reddy, Suja T. Dharmabalan*, Kanakaraju Manupati, Ragini Yeeravalli, Lakshmi D. Vijay, Kavitha Donthiboina, Vadithe Lakshma Naik and Amitava Das


DOI: 10.2174/1871520620666200423075630




Open Access Articles


The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

, 2020; 20(13): 1613 - 1625

Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland




Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687 - 699

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang





Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi







Most Cited Articles



Research Article

Beta-caryophyllene suppresses ovarian cancer proliferation by inducing cell cycle arrest and apoptosis

, 2020; 20(13): 1530-1537.

Santhosh Arul, Harinee Rajagopalan, Jivitesh Ravi and Haripriya Dayalan*


DOI: 10.2174/1871520620666200227093216


Research Article

Ruxolitinib regulates the autophagy machinery in multiple myeloma cells

, 2020; 20(18): 2316-2323.

Alican Kusoglu*, Bakiye G. Bagca, Neslihan P.O. Ay, Guray Saydam and Cigir B. Avci


DOI: 10.2174/1871520620666200218105159



Review Article

Aromatase inhibitors for the treatment of breast cancer: A journey from the scratch

, 2020; 20(17): 1994-2004.

Pooja Ratre, Keerti Mishra, Amit Dubey, Amber Vyas, Akhlesh Jain* and Suresh Thareja*


DOI: 10.2174/1871520620666200627204105


Review Article

Nanoformulations of coumarins and the hybrid molecules of coumarins with potential anticancer effects

, 2020; 20(15): 1797-1816.

Mukerrem Betul Yerer*, Serkan Dayan, M. Ihsan Han, Ajay Sharma, Hardeep S. Tuli and Katrin Sak


DOI: 10.2174/1871520620666200310094646


Research Article

Molecular docking, antioxidant, anticancer and antileishmanial effects of newly synthesized quinoline derivatives

, 2020; 20(13): 1516-1529.

Zoonish Malghani, Arif-Ullah Khan*, Muhammad Faheem, Muhammad Z. Danish, Humaira Nadeem, Sameen F. Ansari and Madeeha Maqbool


DOI: 10.2174/1871520620666200516145117



Review Article

Recent advances of silver nanoparticles in cancer diagnosis and treatment

, 2020; 20(11): 1276-1287.

Tran Q. Huy*, Pham T.M. Huyen, Anh-Tuan Le and Matteo Tonezzer*


DOI: 10.2174/1871520619666190710121727


Review Article

Cdk1 in breast cancer: Implications for theranostic potential

, 2020; 20(7): 758-767.

Sepideh Izadi, Afshin Nikkhoo, Mohammad Hojjat-Farsangi, Afshin Namdar, Gholamreza Azizi, Hamed Mohammadi, Mehdi Yousefi and Farhad Jadidi-Niaragh*


DOI: 10.2174/1871520620666200203125712


Research Article

Resveratrol counteracts hypoxia-induced gastric cancer invasion and emt through hedgehog pathway suppression

, 2020; 20(9): 1105-1114.

Qin-Hong Xu, Ying Xiao, Xu-Qi Li*, Lin Fan*, Can-Can Zhou, Liang Cheng, Zheng-Dong Jiang and Guang-Hui Wang


DOI: 10.2174/1871520620666200402080034


Research Article

Evaluation of the diagnostic properties of serum hsa-mir-223-5p in the detection of gastric cancer: A case-control study

, 2020; 20(7): 800-808.

Amir H. Aalami, Vahid Pouresmaeil*, Amir Amirabadi, Fatemeh H. Mojahed, Mahdi Q. Rad and Amirhossein Sahebkar*


DOI: 10.2174/1871520620666200204100602


Research Article

Anti-tumour activity of glycodendrimer nanoparticles in a subcutaneous mec-1 xenograft model of human chronic lymphocytic leukemia

, 2020; 20(3): 325-334.

Barbara Ziemba, Hanna Sikorska, Magdalena Jander, Wojciech Kuncman, Marian Danilewicz, Dietmar Appelhans, Maria Bryszewska, Maciej Borowiec and Ida Franiak-Pietryga*


DOI: 10.2174/1871520619666191019093558


Research Article

Molecular docking study, cytotoxicity, cell cycle arrest and apoptotic induction of novel chalcones incorporating thiadiazolyl isoquinoline in cervical cancer

, 2020; 20(1): 70-83.

Mohamed A. Tantawy, Farid M. Sroor*, Magda F. Mohamed*, Mostafa E. El-Naggar, Fatma M. Saleh, Hamdi M. Hassaneen and Ismail A. Abdelhamid*


DOI: 10.2174/1871520619666191024121116



Most Accessed Articles


Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687-699.

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang


DOI: 10.2174/1871520620666200213102849



The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators

, 2021; 21(2): 254-266.

Khandan Ilkhani, Milad Bastami, Soheila Delgir, Asma Safi, Shahrzad Talebian and Mohammad-Reza Alivand*


DOI: 10.2174/1871520620666200910123428




Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular docking and DNA Fragmentation

, 2021; 21(6): 703-715.

Jean C. Benassi, Flavio A.R. Barbosa, Valdelúcia M.A.S. Grinevicius, Fabiana Ourique, Daniela Coelho, Karina B. Felipe, Antônio L. Braga, Danilo W. Filho and Rozangela C. Pedrosa*


DOI: 10.2174/1871520620666200728124640



A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment

, 2021; 21(2): 149-161.

Ahmed El-Hussein*, Sello L. Manoto, Saturnin Ombinda-Lemboumba, Ziya A. Alrowaili and Patience Mthunzi-Kufa


DOI: 10.2174/1871520620666200403144945




Antibody-Based Targeted Interventions for the Diagnosis and Treatment of Skin Cancers

, 2021; 21(2): 162-186.

Suresh Madheswaran, Neelakshi Mungra, Fleury A.N. Biteghe, Jean De la Croix Ndong, Afolake T. Arowolo, Henry A. Adeola, Dharanidharan Ramamurthy, Krupa Naran, Nonhlanhla P. Khumalo and Stefan Barth*


DOI: 10.2174/1871520620666200728123006




Flavonoid-Based Cancer Therapy: An Updated Review

, 2020; 20(12): 1398-1414.

Elham Hosseinzadeh, Ali Hassanzadeh, Faroogh Marofi, Mohammad Reza Alivand and Saeed Solali*


DOI: 10.2174/1871520620666200423071759



Editor-in-Chief

Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)
Biography
View Full Editorial Board

COPE Compliant

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

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