Bentham Science Logo
Journal Cover

Track Your Manuscript:


Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Volume 21, 18 Issues, 2021
ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)
This journal supports open access

Aims & Scope

Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.

Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication.

Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.

Anti-Cancer Agents in Medicinal Chemistry

,

Volume 21

-

Number 15



Biography   Open Access





Review Article

Application of Diffusion Weighted Imaging in Prostate Cancer Bone Metastasis: Detection and Therapy Evaluation

, 21(15): 1950 - 1956

Xue-Qin Gong, Yun-Yun Tao, Ran Wang, Nian Liu, Xiao-Hua Huang, Jing Zheng, Cui Yang, Lin Yang* and Xiao-Ming Zhang


DOI: 10.2174/1871520621666210118092641












Articles Ahead of Print











Abstracts Ahead of Print

Repurposing drugs as novel triple negative breast cancer therapeutics


Amiya Das, Pallavi Agarwal, Gaurav Kumar Jain, Geeta Aggarwal, Viney Lather* and Deepti Pandita*


DOI: 10.2174/1871520621666211021143255
View Abstract




Lobaplatin induces pyroptosis in cervical cancer cells via caspase-3/GSDME pathway


Jie Chen , Lili Ge , Xiaoyan Shi, Juan Liu, Hongjie Ruan, Dou Heng and Chunping Ye*


DOI: 10.2174/1871520621666211018100532
View Abstract



Apoptotic Effect of Gemini Curcumin on MDA-MB-468 Breast Cancer Cell Line


Masoumeh Hajizadeh, Salar Hafez Ghoran, Hewa Jalal Azeez, Mohammad Ali Hosseinpour Feizi and Esmaeil Babaei*


DOI: 10.2174/1871520621666211015141928
View Abstract






Published Contents

Editor's Choice

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole- Based Anticancer Agents as Potent Angiogenesis Inhibitors

, 2021; 21(15): 2041 - 2049

Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu*, Ayşe T. Koparal, Gülhan Turan, Ali S. Koparal and Zafer A. Kaplancıklı


DOI: 10.2174/1871520621666201231143535



Synthetic Spirocyclohexadienones as New Anti-Migratory Compounds in Triple- Negative Breast Cancer Cell Migration

, 2021; 21(14): 1901 - 1910

Wanessa F. Altei, Bianca C. Pachane, Lucimara J. Martins, Ralph C. Gomes, Ricardo N. Santos, Daniara C. Fernandes, Heloisa S. Selistre-de-Araújo, Fernando Coelho * and Adriano D. Andricopulo*


DOI: 10.2174/1871520621666201207092836






Synthesis of 1H-1,2,3-Triazole-Linked Quinoline-Isatin Molecular Hybrids as Anti-Breast Cancer and Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Agents

, 2021; 21(10): 1228 - 1239

Paul Awolade, Nosipho Cele, Oluwakemi Ebenezer, Nagaraju Kerru, Lalitha Gummidi, Liang Gu, Gabriella Palma, Mandeep Kaur and Parvesh Singh*


DOI: 10.2174/1871520620666200929153138



On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids against Breast Tumor Cells (MDA-231 and MCF-7)

, 2021; 21(9): 1172 - 1182

Celisnolia M. Leite*, João Honorato de Araujo-Neto, Rodrigo S. Corrêa, Legna Colina-Vegas, Diego Martínez-Otero, Paulo R. Martins, Cristiane G. Silva and Alzir A. Batista*


DOI: 10.2174/1871520620666200824114816



Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives

, 2021; 21(8): 963 - 986

Samir M. Awad, Mosaad S. Mohamed, Marwa Abd El-Fattah Khodair and Rania H. Abd El-Hameed*


DOI: 10.2174/1871520620666200925103742




Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular Docking and DNA Fragmentation

, 2021; 21(6): 703 - 715

Jean C. Benassi, Flavio A.R. Barbosa, Valdelúcia M.A.S. Grinevicius, Fabiana Ourique, Daniela Coelho, Karina B. Felipe, Antônio L. Braga, Danilo W. Filho and Rozangela C. Pedrosa*


DOI: 10.2174/1871520620666200728124640



Open Access Articles


The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

, 2020; 20(13): 1613 - 1625

Joseph Mazar*, Caleb Gordon, Varun Naga and Tamarah J. Westmoreland




Cytotoxic Sesquiterpenes from Sonchus oleraceus

, 2020; 20(6): 709 - 714

Hongying Zhang, Yiding Wang, Shaojiu Wang, Qian Wang, Tianjing Wang, Jie Zhu* and Bing Liu




Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug- Resistant Cells

, 2020; 20(6): 687 - 699

Gongshen Jin*, Kangwei Wang, Yonghong Liu, Xianhu Liu, Xiaojing Zhang and Hao Zhang





Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through the Inhibition of Angiogenesis

, 2019; 19(10): 1253 - 1261

Naipeng Cui, Dan-Dan Lin, Yang Shen, Jian-Guo Shi, Bing Wang, Ming-Zhi Zhao, Lishuang Zheng, Hua Chen* and Jian-Hong Shi*





New Strategies for Therapeutic Cancer Vaccines

, 2019; 19(2): 213 - 221

Hanjiao Qin, Jiyao Sheng, Dan Zhang, Xuewen Zhang, Linlin Liu*, Bingjin Li*, Guangquan Li* and Zhuo Zhang




Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?

, 2018; 18(8): 1091 - 1099

Chengshui Liao*, Xiangchao Cheng, Mingyuan Liu*, Xuelin Wang and Pascal Boireau




Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation

, 2018; 18(7): 1001 - 1008

Na Li, Kun Zhang, Xin Mu, Qiong Tian, Wenli Liu, Tianyuan Gao, Xiaona Ma* and Jian Zhang*





Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Most Cited Articles



Review Article

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention

, 2019; 19(1): 38-47.

Alessandro Colapietro, Andrea Mancini, Anna Maria D'Alessandro and Claudio Festuccia*


DOI: 10.2174/1871520619666181231112453




Research Article

Synthesis and biological evaluation of novel heterocyclic imines linked coumarin- thiazole hybrids as anticancer agents

, 2019; 19(4): 557-566.

Nerella S. Goud, Mahammad S. Ghouse, Jatoth Vishnu, Jakkula Pranay, Ravi Alvala, Venu Talla, Insaf A. Qureshi and Mallika Alvala*


DOI: 10.2174/1871520619666190207140120


Review Article

Phytochemicals in anticancer drug development

, 2019; 19(2): 172-183.

Rohit Dutt, Vandana Garg, Naveen Khatri and Anil K. Madan*


DOI: 10.2174/1871520618666181106115802


Review Article

Nitrogen-containing heterocycles as anticancer agents: An overview

, 2020; 20(18): 2150-2168.

Damanpreet K. Lang, Rajwinder Kaur*, Rashmi Arora, Balraj Saini and Sandeep Arora


DOI: 10.2174/1871520620666200705214917


Review Article

Quercetin loaded nanoparticles in targeting cancer: Recent development

, 2019; 19(13): 1560-1576.

Manjula Vinayak* and Akhilendra K. Maurya


DOI: 10.2174/1871520619666190705150214


Research Article

Let-7a could serve as a biomarker for chemo-responsiveness to docetaxel in gastric cancer

, 2019; 19(3): 304-309.

Najibeh Shekari, Faezeh Asghari, Navideh Haghnavaz, Dariush Shanehbandi, Vahid Khaze, Behzad Baradaran and Tohid Kazemi*


DOI: 10.2174/1871520619666181213110258



Research Article

Ginsenoside Rh2 inhibits migration of lung cancer cells under hypoxia via mir-491

, 2019; 19(13): 1633-1641.

Yingying Chen, Yuqiang Zhang, Wei Song, Ying Zhang, Xiu Dong and Mingqi Tan*


DOI: 10.2174/1871520619666190704165205



Research Article

Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

, 2019; 19(4): 463-472.

Evgenii S. Mozhaitsev, Alexandra L. Zakharenko, Evgeniy V. Suslov*, Dina V. Korchagina, Olga D. Zakharova, Inna A. Vasil'eva, Arina A. Chepanova, Ellena Black, Jinal Patel, Raina Chand, Jóhannes Reynisson, Ivanhoe K.H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov and Olga I. Lavrik


DOI: 10.2174/1871520619666181207094243




Most Accessed Articles

Synthetic Spirocyclohexadienones as New Anti-Migratory Compounds in Triple- Negative Breast Cancer Cell Migration

, 2021; 21(14): 1901-1910.

Wanessa F. Altei, Bianca C. Pachane, Lucimara J. Martins, Ralph C. Gomes, Ricardo N. Santos, Daniara C. Fernandes, Heloisa S. Selistre-de-Araújo, Fernando Coelho * and Adriano D. Andricopulo*


DOI: 10.2174/1871520621666201207092836



Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells

, 2021; 21(14): 1911-1920.

Maiara B. Marques, Ayane P. Machado, Priscila A. Santos, Michele Carrett-Dias, Gabriela S. Araújo, Barbara da Silva Alves, Bárbara Santos de Oliveira, Flavio M.R. da Silva Júnior, Cristiana L. Dora, Andrés D. Cañedo, Daza M.V.B. Filgueira, Estela Fernandes e Silva* and Ana Paula de Souza Votto


DOI: 10.2174/1871520621999210104200722





Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole- Based Anticancer Agents as Potent Angiogenesis Inhibitors

, 2021; 21(15): 2041-2049.

Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu*, Ayşe T. Koparal, Gülhan Turan, Ali S. Koparal and Zafer A. Kaplancıklı


DOI: 10.2174/1871520621666201231143535


Anti-Tumor Activity and Underlying Mechanism of Phomoxanthone B in MCF7 Cells

, 2021; 21(14): 1825-1834.

Chuan Chen, Ziyue Zhao, Qian Dong, XueHui Gao, Huibin Xu, Runlei Yang, JianChun Qin* and Duqiang Luo*


DOI: 10.2174/1871520620999201124215511


1,3,4-Thiadiazolo (3,2-Α) Pyrimidine-6-Carbonitrile Scaffold as PARP1 Inhibitors

, 2021; 21(15): 2050-2065.

Lakshmanan Kaviarasan, Elizabeth Eldhose, Praveen T. Krishnamurthy, Kalirajan Rajagopal, Manal Mohammed, Pulla Prudviraj and Gowramma Byran*


DOI: 10.2174/1871520621666201216095018




Alpha-Terpineol as Antitumor Candidate in Pre-Clinical Studies

, 2021; 21(15): 2023-2031.

Helber A. Negreiros, Kariely Gonçalves de Moura, Maria L.L. Barreto do Nascimento, Débora Caroline do Nascimento Rodrigues, Paulo M.P. Ferreir, Débora C. Braz, Marlene Gomes de Farias, Layde de Sousa Corrêia, Ana R.S. Pereira, Lubna K.B. Santos, Juan C.R. Gonçalves, Anderson N. Mendes, Felipe C. Carneiro da Silva, Ana A.C.M. Cavalcant and Joáo Marcelo de Castro e Sousa*


DOI: 10.2174/1871520621999210104195820


The Efficacy and Safety of Additional Anti-HER2-Targeting Drugs in the Treatment of HER2-Positive Advanced Breast Cancer: A Meta-Analysis

, 2021; 21(14): 1931-1940.

Nannan Du, Bangsheng Chen, Zefeng Shen, Bin Zhou, Xiaojun Fu, Danyi Mao, Feiyan Mao, Derry M. Ng, Parikshit A. Khadaroo and Lei Yang*


DOI: 10.2174/1871520621666201231142841


Application of Diffusion Weighted Imaging in Prostate Cancer Bone Metastasis: Detection and Therapy Evaluation

, 2021; 21(15): 1950-1956.

Xue-Qin Gong, Yun-Yun Tao, Ran Wang, Nian Liu, Xiao-Hua Huang, Jing Zheng, Cui Yang, Lin Yang* and Xiao-Ming Zhang


DOI: 10.2174/1871520621666210118092641





Editor-in-Chief

graphic
Simone Carradori
Department of Pharmacy
“G. d’Annunzio” University of Chieti-Pescara
Chieti
(Italy)
Biography
View Full Editorial Board

COPE Compliant

Cope Logo

Journal History

Current Medicinal Chemistry - Anti-Cancer Agents was launched in 2001 and later renamed in 2006 as Anti-Cancer Agents in Medicinal Chemistry.

Related Journals

Related eBooks

eBooks Catalog