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Current Alzheimer Research

Volume 18, 14 Issues, 2021
ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)
This journal supports open access

Aims & Scope

Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Current Alzheimer Research

,

Volume 18

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Number 2



Review Article

Retinal Changes in Transgenic Mouse Models of Alzheimer’s Disease

, 18(2): e140421192840

Li Guo*, Nivedita Ravindran, Ehtesham Shamsher, Daniel Hill and M. Francesca Cordeiro


DOI: 10.2174/1567205018666210414113634


Systematic Review Article



Meta-Analysis

Weight Loss and the Risk of Dementia: A Meta-analysis of Cohort Studies

, 18(2): e140421192839

Chao Wang, Wenning Fu, Shiyi Cao, Heng Jiang, Yingying Guo, Hongbin Xv, Jianxin Liu, Yong Gan* and Zuxun Lu*


DOI: 10.2174/1567205018666210414112723




Research Article

Development and Validation of a Model to Identify Alzheimer’s Disease and Related Syndromes in Administrative Data

, 18(2): e160421192875

Adeline Gallini, David Jegou, Maryse Lapeyre-Mestre, Anaïs Couret, Robert Bourrel, Pierre-Jean Ousset, D Fabre, Sandrine Andrieu and Virginie Gardette*


DOI: 10.2174/1567205018666210416094639


Research Article   Open Access

Cerebrospinal Fluid Inflammatory Markers in Alzheimer’s Disease: Influence of Comorbidities

, 18(2): e300321192525

Ying Wang, Ceren Emre, Helena Gyllenhammar-Schill, Karin Fjellman, Helga Eyjolfsdottir, Maria Eriksdotter, Marianne Schultzberg and Erik Hjorth*


DOI: 10.2174/1567205018666210330162207




Case Report

PET/MRI Delivers Multimodal Brain Signature in Alzheimer’s Disease with De Novo PSEN1 Mutation

, 18(2): e140421192838

Gayane Aghakhanyan, Dorothee Saur, Michael Rullmann, Christopher M. Weise, Matthias L. Schroeter, Ken Marek, Rami Abou Jamra, Solveig Tiepolt, Maria Strauss, Cordula Scherlach, Karl-Titus Hoffmann, Osama Sabri, Joseph Classen and Henryk Barthel*


DOI: 10.2174/1567205018666210414111536


Current Alzheimer Research, Volume 18 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Abstracts Ahead of Print


Real-world Utilisation of the Rivastigmine Transdermal Patches Accompanying the use of Risk Minimisation Tools in Patients with Dementia


Fritjof Reinhardt, Nikolaos Scarmeas, Rajesh Karan, Uday Kiran Veldandi, Sunil Modali*, Krishna Duvvuri and Rashid Khan Pathan


DOI: 10.2174/1567205018666210716120540
View Abstract


Pregabalin Treatment does not Affect Amyloid Pathology in 5XFAD Mice


Katherine R. Sadleir*, Jelena Popovoic, Wei Zhu, Cory T. Reidel, Ha Do, Richard B. Silverman and Robert Vassar


DOI: 10.2174/1567205018666210713125333
View Abstract


Longitudinal Functional Magnetic Resonance Spectroscopy Study in Subjects with Mild Cognitive Impairment and Alzheimer’s Disease


Soo-Hyun Cho, Hak Young Rhee, Janghoon Oh, Jin San Lee, Soonchan Park, Won Chul Shin, Jong-Woo Paik, Chang-Woo Ryu, Key Chung Park and Geon-Ho Jahng*


DOI: 10.2174/1567205018666210708145924
View Abstract


The Absence of Myelin Basic Protein Reduces Non-Amyloidogenic Processing of Amyloid Precursor Protein


Chika Seiwa*, Ichiro Sugiyama , Makoto Sugawa, Hiroaki Murase , Chiaki Kudoh and Hiroaki Asou


DOI: 10.2174/1567205018666210701162851
View Abstract


High fat diet aggravates AD-related pathogenic processes in APP/PS1 mice


Xiaokang Gong, Zheng Liang, Wei Liu, Yang Zhao, Youhua Yang, Mengjuan Wu, Jinting Shang, Yifan Xiao, Yong Mei, Qiqi Su, Binlian Sun, Jian Bao* and Xiji Shu


DOI: 10.2174/1567205018666210628100812
View Abstract


Beneficial Effects of Choline Alphoscerate on Amyloid-β Neurotoxicity in an In vitro Model of Alzheimer’s Disease


Chiara Burgaletto, Giulia Di Benedetto, Antonio Munafò, Renato Bernardini and Giuseppina Cantarella*


DOI: 10.2174/1567205018666210608093658
View Abstract


Published Contents

Editor's Choice

Cerebrospinal Fluid Inflammatory Markers in Alzheimer’s Disease: Influence of Comorbidities

, 2021; 18(2): 157 - 170

Ying Wang, Ceren Emre, Helena Gyllenhammar-Schill, Karin Fjellman, Helga Eyjolfsdottir, Maria Eriksdotter, Marianne Schultzberg and Erik Hjorth*


DOI: 10.2174/1567205018666210330162207



Retinal Changes in Transgenic Mouse Models of Alzheimer’s Disease

, 2021; 18(2): 89 - 102

Li Guo*, Nivedita Ravindran, Ehtesham Shamsher, Daniel Hill and M. Francesca Cordeiro


DOI: 10.2174/1567205018666210414113634



Clinical Application of the Vestibular Stimulation Effect on Balance Disorders with Dementia

, 2021; 18(1): 1 - 7

Kiyotaka Nakamagoe*, Shiori Yamada, Rio Kawakami, Takami Maeno, Tadachika Koganezawa and Akira Tamaoka


DOI: 10.2174/1567205018666210324105642



APP/PS1 Gene-Environment Noise Interaction Aggravates AD-like Neuropathology in Hippocampus Via Activation of the VDAC1 Positive Feedback Loop

, 2021; 18(1): 14 - 24

Huimin Chi, Qingfeng Zhai, Ming Zhang, Donghong Su, Wa Cao, Wenlong Li, Xiaojun She, Honglian Yang, Kun Wang, Xiujie Gao, Kefeng Ma, Bo Cui* and Yugang Qiu*


DOI: 10.2174/1567205018666210324114153



Nanoparticle-Encapsulated Bryostatin-1 Activates α-Secretase and PKC Isoforms In vitro and Facilitates Acquisition and Retention of Spatial Learning in an Alzheimer's Disease Mouse Model

, 2020; 17(14): 1302 - 1310

Lisa Schrott, Ping Yi, Kasey Jackson, Gabriel S. Jackson, Christopher Webb, Alireza Minagar, J. Winny Yun, Geoffrey Purdum, David J. Rios, Theodore A. Tyler, Maria I. Vizcanio, Judith L. Castor, Trevor Castor and Jonathan S. Alexander*


DOI: 10.2174/1567205018666210218155835




Diagnosis of Mild Cognitive Impairment Using Cognitive Tasks: A Functional Near-Infrared Spectroscopy Study

, 2020; 17(13): 1145 - 1160

So-Hyeon Yoo, Seong-Woo Woo, Myung-Jun Shin, Jin A. Yoon, Yong-Il Shin and Keum-Shik Hong*


DOI: 10.2174/1567205018666210212154941






Open Access Articles

Cerebrospinal Fluid Inflammatory Markers in Alzheimer’s Disease: Influence of Comorbidities

, 2021; 18(2): 157 - 170

Ying Wang, Ceren Emre, Helena Gyllenhammar-Schill, Karin Fjellman, Helga Eyjolfsdottir, Maria Eriksdotter, Marianne Schultzberg and Erik Hjorth*




Social Network Analysis of Alzheimer’s Teams: A Clinical Review and Applications in Psychiatry to Explore Interprofessional Care

, 2021; 18: 1 - 19 (E-Pub Ahead of Print)

Carlo Lazzari*, Yasuhiro Kotera, Pauline Green and Marco Rabottini





Statins, Risk of Death and Ischemic Stroke in Patients with Dementia: A Registry-Based Observational Cohort Study

, 2020; 17(10): 881 - 892

Bojana Petek*, Hong Xu, Marta Villa-Lopez, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek*




Cerebrospinal Fluid and Blood CX3CL1 as a Potential Biomarker in Early Diagnosis and Prognosis of Dementia

, 2020; 17(8): 709 - 721

Agnieszka Kulczyńska-Przybik*, Agnieszka Słowik, Piotr Mroczko, Bartłomiej Borawski, Magdalena Groblewska, Renata Borawska and Barbara Mroczko




Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China

, 2020; 17(6): 540 - 546

Jiajia Zhou, Yi Chen, Fanxia Meng, Kan Zhang, Xiaoyan Liu and Guoping Peng*




The Parietal Atrophy Score on Brain Magnetic Resonance Imaging is a Reliable Visual Scale

, 2020; 17(6): 534 - 539

David Silhan, Ales Bartos*, Jana Mrzilkova, Olga Pashkovska, Ibrahim Ibrahim and Jaroslav Tintera





Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

, 2020; 17(3): 285 - 296

Gernot Riedel , Jochen Klein , Grazyna Niewiadomska, Constantin Kondak , Karima Schwab , Dilyara Lauer , Mandy Magbagbeolu , Marta Steczkowska, Maciej Zadrozny , Malgorzata Wydrych , Anna Cranston , Valeria Melis, Renato X. Santos , Franz Theuring , Charles R. Harrington and Claude M. Wischik*




Dangerous Liaisons: Tau Interaction with Muscarinic Receptors

, 2020; 17(3): 224 - 237

Adrianna Wysocka, Ewelina Palasz, Marta Steczkowska and Grazyna Niewiadomska*




Association Between Anemia and Dementia: A Nationwide, Populationbased Cohort Study in Taiwan

, 2020; 17(2): 196 - 204

Chien-Tai Hong, Yi-Chen Hsieh, Hung-Yi Liu, Hung-Yi Chiou and Li-Nien Chien*




Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer’s Disease: The Shanghai Aging Study

, 2020; 17(2): 185 - 195

Jianxiong Xi, Ding Ding*, Qianhua Zhao, Xiaoniu Liang, Li Zheng, Qihao Guo, Zhen Hong, Hua Fu, Jianfeng Xu and Qianyi Xiao*




Intracranial Atherosclerotic Stenosis is Related to Post-stroke Cognitive Impairment: A Cross-sectional Study of Minor Stroke

, 2020; 17(2): 177 - 184

Li Gong, Haichao Wang, Qiong Dong, Xiaoping Zhu, Xiaoran Zheng, Yongzhe Gu, Wangli Cai, Yanxin Zhao* and Xueyuan Liu*




Automatic Detection of Cognitive Impairments through Acoustic Analysis of Speech

, 2020; 17(1): 60 - 68

Ryosuke Nagumo*, Yaming Zhang, Yuki Ogawa, Mitsuharu Hosokawa, Kengo Abe, Takaaki Ukeda, Sadayuki Sumi, Satoshi Kurita, Sho Nakakubo, Sangyoon Lee, Takehiko Doi and Hiroyuki Shimada




Tau PET Distributional Pattern in AD Patients with Visuospatial Dysfunction

, 2019; 16(11): 1055 - 1062

Xi Sun, Binbin Nie, Shujun Zhao, Qian Chen, Panlong Li, Tianhao Zhang, Tingting Pan, Ting Feng, Luying Wang, Xiaolong Yin, Wei Zhang, Shilun Zhao, Baoci Shan, Hua Liu*, Shengxiang Liang*, Lin Ai* and Guihong Wang*





Most Cited Articles




Review Article

Mitigating Alzheimer’s disease with natural polyphenols: A review

, 2019; 16(6): 529-543.

Roger Gaudreault* and Normand Mousseau*


DOI: 10.2174/1567205016666190315093520



Research Article

Resveratrol rescues tau-induced cognitive deficits and neuropathology in a mouse model of tauopathy

, 2019; 16(8): 710-722.

Xiao-Ying Sun, Quan-Xiu Dong, Jie Zhu, Xun Sun, Li-Fan Zhang, Mandy Qiu, Xiao-Lin Yu* and Rui-Tian Liu*


DOI: 10.2174/1567205016666190801153751


Review Article

Neuroinflammation in alzheimer’s disease: Microglia, molecular participants and therapeutic choices

, 2019; 16(7): 659-674.

Haijun Wang, Yin Shen, Haoyu Chuang, Chengdi Chiu, Youfan Ye and Lei Zhao*


DOI: 10.2174/1567205016666190503151648




Research Article

The temporal relationship between pain intensity and pain interference and incident dementia

, 2019; 16(2): 109-115.

Ali Ezzati*, Cuiling Wang, Mindy J. Katz, Carol A. Derby, Andrea R. Zammit, Molly E. Zimmerman, Jelena M. Pavlovic, Martin J. Sliwinski and Richard B. Lipton


DOI: 10.2174/1567205016666181212162424


Review Article

Learning from the past: A review of clinical trials targeting amyloid, tau and neuroinflammation in Alzheimer’s disease

, 2020; 17(2): 112-125.

Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto and Benjamin B. Tournier*


DOI: 10.2174/1567205017666200304085513


Review Article

Biomarkers for alzheimer’s disease

, 2019; 16(6): 518-528.

Leonardo Guzman-Martinez, Ricardo B. Maccioni*, Gonzalo A. Farías, Patricio Fuentes and Leonardo P. Navarrete


DOI: 10.2174/1567205016666190517121140


Systematic Review Article

Depression in dementia or dementia in depression? Systematic review of studies and hypotheses

, 2020; 17(1): 16-28.

Agnieszka Brzezińska, Julius Bourke, Rayito Rivera-Hernández, Magda Tsolaki, Joanna Wożniak and Jakub Każmierski*


DOI: 10.2174/1567205017666200217104114


Systematic Review Article

Physical activity as a moderator of alzheimer pathology: A systematic review of observational studies

, 2019; 16(4): 362-378.

Kristian Steen Frederiksen*, Le Gjerum, Gunhild Waldemar and Steen Gregers Hasselbalch


DOI: 10.2174/1567205016666190315095151


Review Article

Pharmacological interventions to attenuate Alzheimer’s disease progression: The story so far

, 2019; 16(3): 261-277.

Firas H. Bazzari*, Dalaal M. Abdallah and Hanan S. El-Abhar


DOI: 10.2174/1567205016666190301111120



Most Accessed Articles


Parkinson’s Symptoms and Caregiver Affiliate Stigma: A Multinational Study

, 2021; 18(3): 222-231.

Richard S. Henry, Paul B. Perrin*, Sarah K. Lageman, Teresita Villaseñor, Annahir N. Cariello, Mickeal Pugh, Jr., Erin R. Smith, Monica Arroyo, Alejandra Zarate, Judith Avila and Jose A. Soto-Escageda


DOI: 10.2174/1567205018666210608100917





Reading Fluency in Spanish Patients with Alzheimer’s Disease

, 2021; 18(3): 243-255.

María del Carmen Pérez-Sánchez, María González-Nosti*, Fernando Cuetos, Carmen Martínez and Marta Álvarez-Cañizo


DOI: 10.2174/1567205018666210608102012


Clinical Phenotype and Mutation Spectrum of Alzheimer`s Disease with Causative Genetic Mutation in a Chinese Cohort

, 2021; 18(3): 265-272.

Chenhui Mao, Jie Li, Liling Dong, Xinying Huang, Dan Lei, Jie Wang, Shanshan Chu, Caiyan Liu, Bin Peng, Gustavo C. Román, Liying Cui and Jing Gao*


DOI: 10.2174/1567205018666210608120339


123I-Ioflupane SPECT and 18F-FDG PET Combined Use in the Characterization of Movement and Cognitive Associated Disorders in Neurodegenerative Diseases

, 2021; 18(3): 196-207.

Susanna Nuvoli*, Giovanna Tanda, Maria L. Stazza, Barbara Palumbo, Viviana Frantellizzi, Giuseppe De Vincentis, Angela Spanu and Giuseppe Madeddu


DOI: 10.2174/1567205018666210608112302


Depression in Dementia or Dementia in Depression? Systematic Review of Studies and Hypotheses

, 2020; 17(1): 16-28.

Agnieszka Brzezińska, Julius Bourke, Rayito Rivera-Hernández, Magda Tsolaki, Joanna Woźniak and Jakub Kaźmierski*


DOI: 10.2174/1567205017666200217104114



Association of Dietary Habits with Mild Cognitive Impairment among Elderly in Rural Area of North China

, 2021; 18(3): 256-264.

Huilian Duan, Changqing Sun, Yun Zhu, Qian Liu, Yue Du, Hongyan Lin, Mengdi Jin, Jingzhu Fu, Fei Ma, Wen Li, Huan Liu, Jing Yan, Yongjie Chen, Guangshun Wang and Guowei Huang*


DOI: 10.2174/1567205018666210617152205


Learning from the Past: A Review of Clinical Trials Targeting Amyloid, Tau and Neuroinflammation in Alzheimer’s Disease

, 2020; 17(2): 112-125.

Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto and Benjamin B. Tournier*


DOI: 10.2174/1567205017666200304085513


Volumetric MRI Demonstrates Atrophy of the Olfactory Cortex in AD

, 2020; 17(10): 904-915.

Majed Al-Otaibi, Melissa Lessard-Beaudoin, Christian-Alexandre Castellano, Denis Gris, Stephen C. Cunnane and Rona K. Graham*


DOI: 10.2174/1567205017666201215120909


Clinical Application of the Vestibular Stimulation Effect on Balance Disorders with Dementia

, 2021; 18(1): 1-7.

Kiyotaka Nakamagoe*, Shiori Yamada, Rio Kawakami, Takami Maeno, Tadachika Koganezawa and Akira Tamaoka


DOI: 10.2174/1567205018666210324105642





Editor-in-Chief

graphic
Prof. Debomoy K. Lahiri
(16607 citations)
Neuroscience Research Center
Indianapolis, IN 46202
(USA)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

graphic
Prof. Jean-Marie Lehn
(France)

graphic
Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Alzheimer Research was introduced in 2004 with the assistance of Dr. Debomoy K. Lahiri, who is the current Editor-in-Chief serving since 2004.
New eBook

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Frontiers in Clinical Drug Research – Alzheimer Disorders



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