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Current Chemical Biology

Volume 15, 4 Issues, 2021
ISSN: 1872-3136 (Online)
ISSN: 2212-7968 (Print)
This journal supports open access

Aims & Scope

Current Chemical Biology aims to publish full-length and mini reviews as well as research papers on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Chemical Mechanisms of Biological Systems (Mechanisms of drug design; Molecular recognition; Enzyme inhibition mechanisms; Chemical mechanisms of biological functions; Molecular machines; Chemical ecology; Metal ions in biological systems; Metalloenzymes; Chemical mechanisms, proteomics and metabonomics; Chemical imaging; Small molecule-biological target interactions; Biologically active natural products; Elucidation of biosynthetic pathways; and Simulation and modeling of biomolecules).

Current Chemical Biology

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Volume 15

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Number 1



Preface   Open Access



Biography   Open Access





Review Article

Targeting Protein Degradation in Cancer Treatment

, 15(1): 5 - 18

Imane Bjij, Ismail Hdoufane, Mahmoud Soliman, Menče Najdoska-Bogdanov and Driss Cherqaoui*


DOI: 10.2174/2212796814999200609131623








Review Article

Molecular Processes Involved in Pancreatic Cancer and Therapeutics

, 15(1): 85 - 108

Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819


Open Access Articles

Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 2020; 14(4): 289 - 303

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*




Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279 - 288

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*




Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14(3): 153 - 168

Mohammad W. Islam, Samir H. Bloukh, Zehra Edis* and Sabrina A. Gacem




POCl3 Mediated Syntheses, Pharmacological Evaluation and Molecular Docking Studies of Some Novel Benzofused Thiazole Derivatives as a Potential Antioxidant and Anti-inflammatory Agents

, 2020; 14(1): 58 - 68

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale





Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells

, 2020; 14(1): 38 - 47

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *










Functional Characterization of Chitin and Chitosan

, 2009; 3(2): 203 - 230

Inmaculada Aranaz, Marian Mengibar, Ruth Harris, Ines Panos, Beatriz Miralles, Niuris Acosta, Gemma Galed and Angeles Heras




Cause of Chirality Consensus

, 2008; 2(2): 153 - 158

Salla Jaakkola, Vivek Sharma and Arto Annila






Most Cited Articles

Review Article

Endogenous repair system of oxidative damage of DNA

, 2019; 13(2): 110-119.

Anmol Sharma, Pawan Gupta and Pranav Kumar Prabhakar*


DOI: 10.2174/2212796813666190221152908




Research Article

Antimicrobial activity of highly fluorinated thiocarbamates and dithiocarbamates

, 2019; 13(2): 120-128.

Amal Thebti, Ines Chniti, Med Abderrahmane Sanhoury*, Ikram Chehidi, Hadda Imene Ouzari and Abdellatif Boudabous


DOI: 10.2174/2212796812666180907153901


Research Article

RNAi-mediated resistance against plant parasitic nematodes of wheat plants obtained in vitro using bioregulators of microbiological origin

, 2019; 13(1): 73-89.

Victoria A. Tsygankova *, Yaroslav V. Andrusevich, Elena N. Shysha, Lyudmila O. Biliavska, Tatyana O. Galagan, Anatoly P. Galkin, Alla I. Yemets , Galina A. Iutynska and Yaroslav B. Blume


DOI: 10.2174/2212796812666180507130017


Research Article

Bioremediation of simulated textile effluent by an efficient bio-catalyst purified from a novel pseudomonas fluorescence lip-rl5

, 2020; 14(2): 128-139.

Ranju K. Rathour, Vaishali Sharma, Nidhi Rana, Ravi K. Bhatia and Arvind K. Bhatt*


DOI: 10.2174/2212796814666200406100247



Research Article

Cytotoxicity evaluation of dimethoxy and trimethoxy indanonic spiroisoxazolines against cancerous liver cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807



Research Article

Insight on ameliorative role of selenium nanoparticles and niacin in wound healing on adult female albino mice

, 2020; 14(3): 169-186.

Marwa Emam, Akaber T. Keshta, Yasser M.A. Mohamed and Yasser A. Attia*


DOI: 10.2174/2212796814666200818111849


Research Article

Nigella sativa seed protects against cadmium-induced renal toxicity in rats

, 2020; 14(2): 140-149.

Ikenna Kingsley Uchendu* and Henshaw Uchechi Okoroiwu


DOI: 10.2174/2212796814666200520083818



Review Article

A recent review on drug modification using 1,2,3-triazole

, 2020; 14(2): 71-87.

Adarsh Sahu*, Preeti Sahu and Ramkishore Agrawal


DOI: 10.2174/2212796814999200807214519


Review Article

Prospective of natural gum nanoparticulate against cardiovascular disorders

, 2019; 13(3): 197-211.

Aakash Deep*, Neeraj Rani, Ashok Kumar, Rimmy Nandal, Prabodh C. Sharma and Arun K. Sharma


DOI: 10.2174/2212796813666190328194825


Current Frontiers

Emerging marine immunomodulatory small-molecules (2010-present)

, 2019; 13(3): 187-196.

Ran Li, Yu-Cheng Gu and Wen Zhang*


DOI: 10.2174/2212796813666190716102614



Most Accessed Articles

Targeting Protein Degradation in Cancer Treatment

, 2021; 15(1): 5-18.

Imane Bjij, Ismail Hdoufane, Mahmoud Soliman, Menče Najdoska-Bogdanov and Driss Cherqaoui*


DOI: 10.2174/2212796814999200609131623



Molecular Processes Involved in Pancreatic Cancer and Therapeutics

, 2021; 15(1): 85-108.

Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819



Ovarian Cancer Biomarkers: Headway Towards Early Diagnosis

, 2021; 15(1): 109-125.

Zeba Mueed, Pankaj Kumar Rai, Seemab Siddique and Nitesh Kumar Poddar*


DOI: 10.2174/2212796815666210121095445



Peaceful Existence of Tumor Cells with Their Non-malignant Neighbors: The Trade of Tumor Cells with Tumor Microenvironment

, 2020; 14(4): 228-239.

Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Hosein Maghsoudi, Mahmood Maniati, Sadra Samavarchi Tehrani* and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943


Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14(4): 279-288.

Iván R Vega-Valdez, Rosalez Melvin N., Santiago-Quintana José M., Farfán-García Eunice D. and Soriano-Ursúa Marvin A.*


DOI: 10.2174/2212796814999201102195651



Differential Metabolites Markers from Trunking and Stressed Non-Trunking Sago Palm (Metroxylon sagu Rottb.)

, 2020; 14(4): 262-278.

Hasnain Hussain*, Wei-Jie Yan, Zainab Ngaini, Norzainizul Julaihi, Rina Tommy and Showkat Ahmad Bhawani


DOI: 10.2174/2212796814999200930120925


DFT Study and Synthesis of Novel Bioactive Bispyrazole using Mg/Al-LDH as a Solid Base Catalyst

, 2020; 14(4): 240-249.

Soufiane Akhramez, Youness Achour, Mustapha Dib, Lahoucine Bahsis*, Hajiba Ouchetto, Abderrafia Hafid, Mostafa Khouili* and Mohammadine El Haddad


DOI: 10.2174/2212796814999200918175018




Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat

, 2020; 14(4): 289-303.

Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509


POCl3 Mediated Syntheses, Pharmacological Evaluation and Molecular Docking Studies of Some Novel Benzofused Thiazole Derivatives as a Potential Antioxidant and Anti-inflammatory Agents

, 2020; 14(1): 58-68.

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale


DOI: 10.2174/2212796813666191118100520



Editor-in-Chief

graphic
Claudio Santi
Department of Pharmaceutical Sciences
University of Perugia
Perugia
(Italy)
Biography
View Full Editorial Board

Journal History

Current Chemical Biology was launched in 2007. Dr. Claudio Santi serves as the Editor-in-Chief of the journal.

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