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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry


Volume 28


Number 3

Biography   Open Access

Review Article (Mini-Review)

Monoclonal Antibodies: A Prospective and Retrospective View

, 28(3): 435 - 471

Jwala Sivaccumar*, Annamaria Sandomenico*, Luigi Vitagliano and Menotti Ruvo*

DOI: 10.2174/0929867327666200219142231

Review Article

Review Article

Advances in L-Type Calcium Channel Structures, Functions and Molecular Modeling

, 28(3): 514 - 524

Lei Xu*, Lilei Sun, Liangxu Xie, Shanzhi Mou, Dawei Zhang, Jingyu Zhu and Peng Xu*

DOI: 10.2174/0929867327666200714154059

Review Article

Is Technical-Grade Chlordane an Obesogen?

, 28(3): 548 - 568

Juliana F. Silva, Bruno P. Moreira, Luís Rato, Maria de Lourdes Pereira, Pedro F. Oliveira and Marco G. Alves*

DOI: 10.2174/0929867327666200121122208

Articles Ahead of Print

Electrostatic Potential Energy in Protein-Drug Complexes

Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo Junior*

DOI: 10.2174/0929867328666210201150842
View Abstract View on PubMed

Recent Advances in Glycosidase Probes Used in Escherichia Coli Detection

Xianhu Wei, Ying Feng, Minling Chen, Shuhong Zhang, Moutong Chen, Jumei Zhang, Youxiong Zhang, Qinghua Ye, Yu Ding, Liang Xue and Qingping Wu*

DOI: 10.2174/0929867328999201224111615
View Abstract View on PubMed

Artificial Intelligence as a Business Partner in Cardiovascular Precision Medicine: An Emerging Approach for Disease Detection and Treatment Optimization

Valeria Visco, Germano Junior Ferruzzi, Federico Nicastro, Nicola Virtuoso, Albino Carrizzo, Gennaro Galasso, Carmine Vecchione and Michele Ciccarelli*

DOI: 10.2174/0929867328666201218122633
View Abstract View on PubMed

Chitosan Nanoparticles Potentiate the in vitro and in vivo Effects of Curcumin and other Natural Compounds

Vanessa Falchetti Lopes, Camila Nascimento Giongo, Laís de Almeida Campos, Wolf-Rainer Abraham, Rubiana Mara Mainardes* and Najeh Maissar Khalil

DOI: 10.2174/0929867328666201124152945
View Abstract View on PubMed

Abstracts Ahead of Print

ICP-MS-based approach to determine nanoparticle recovery after hollow fiber flow field flow fractionation

Fabian L. Kriegel, Benjamin C. Krause, Yves U. Hachenberger*, Rafael Fister, Philipp Reichardt, Jutta Tentschert, Ajay-Vikram Singh*, Harald Jungnickel, Peter Laux and Andreas Luch

DOI: 10.2174/0929867328666210222094913
View Abstract

Lipid-Lowering Therapies for Atherosclerosis: Statins, Fibrates, Ezetimibe and PCSK9 monoclonal antibodies

Adel Hajj Ali, Nour Younis, Rola Abdallah, Farah Shaer, Ali Dakroub, Mohammed Ayoub, Rabah Iratni, Hadi Mohamad Yassine, Kazem Zibara, Alexander Orekhov, Ahmed Fawzy El-Yazbi and Ali Eid *

DOI: 10.2174/0929867328666210222092628
View Abstract

Advances of Inorganic Materials in the Detection and Therapeutic Uses Against Coronaviruses

Sathish Veerasamy*, Manivannan Chandrakumar, Malathi Balasubramaniyan, Ramesh Kumar Arumugam and Thanasekaran Pounraj*

DOI: 10.2174/0929867328666210219142208
View Abstract

Current Trends in the Therapeutic Strategies for Diabetes Management

Ponnurengam Malliappan Siva Kumar, V. Prabhawathi, Ali Zarrabi, Sohail Akthar and Pranav Kumar Prabhakar*

DOI: 10.2174/0929867328666210218183914
View Abstract

Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target

Nastasja Palombi, Annalaura Brai, Martina Gerace, Salvatore Di Maria, Francesco Orofino and Federico Corelli*

DOI: 10.2174/0929867328666210218182203
View Abstract

MicroRNAs in the Management of Heart Failure

Aimilios Kalampogias, Gerasimos Siasos, Evangelos Oikonomou*, Konstantinos Mourouzis, Evanthia Bletsa, Panagiota K. Stampouloglou, Efstratios Katsianos, Konstantinos Vlasis, Georgios Marinos, Georgios Charalambous, Manolis Vavouranakis and Dimitris Tousoulis

DOI: 10.2174/0929867328666210218181441
View Abstract

Published Contents

Open Access Articles

Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

, 2020; 27(42): 7234 - 7255

Soraia Fernandes*, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri and Giancarlo Forte*

Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2020; 27(37): 6356 - 6372

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*

Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

, 2019; 26(11): 1979 - 1993

Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*

Fighting Type-2 Diabetes: Present and Future Perspectives

, 2019; 26(10): 1891 - 1907

Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*

Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*

Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry

, 2019; 26(1): 216 - 231

Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Renata Wawrzyniak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski*

Most Cited Articles

Review Article

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

, 2020; 27(37): 6356-6372.

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*

DOI: 10.2174/0929867326666190730113123

General Review Article

Aptamer-based targeted drug delivery systems: Current potential and challenges

, 2020; 27(13): 2189-2219.

Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*

DOI: 10.2174/0929867325666181008142831

Review Article

Targeting N-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease

, 2020; 27(31): 5250-5272.

Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis Alberto Videla

DOI: 10.2174/0929867326666190410121716

Review Article

Antimicrobial capacity of plant polyphenols against gram-positive bacteria: A comprehensive review

, 2020; 27(15): 2576-2606.

Francisco Javier Álvarez-Martínez, Enrique Barrajón-Catalán*, José Antonio Encinar, Juan Carlos Rodríguez-Díaz and Vicente Micol

DOI: 10.2174/0929867325666181008115650

Review Article

Antiviral activities of human host defense peptides

, 2020; 27(9): 1420-1443.

David C. Brice and Gill Diamond*

DOI: 10.2174/0929867326666190805151654

Review Article

Recent progress in histone deacetylase inhibitors as anticancer agents

, 2020; 27(15): 2449-2493.

Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*

DOI: 10.2174/0929867325666181016163110

Review Article

Structural basis for inhibition of enoyl-[acyl carrier protein] reductase (Inha) from mycobacterium tuberculosis

, 2020; 27(5): 745-759.

Maurício Boff de Ávila, Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo*

DOI: 10.2174/0929867326666181203125229

Review Article

The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival: Prevention and therapeutic implications

, 2020; 27(24): 4087-4108.

Sara Daniela Gomes, Cláudia Suellen Oliveira, João Azevedo-Silva, Marta R. Casanova, Judite Barreto, Helena Pereira, Susana R. Chaves, Lígia R. Rodrigues, Margarida Casal, Manuela Côrte-Real, Fatima Baltazar and Ana Preto*

DOI: 10.2174/0929867325666180530102050

General Review Article

The role of matrix gla protein (MGP) in vascular calcification

, 2020; 27(10): 1647-1660.

Geir Bjørklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth

DOI: 10.2174/0929867325666180716104159

Review Article

Obesity and body composition in man and woman: Associated diseases and the new role of gut microbiota

, 2020; 27(2): 216-229.

Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Giuseppe Palma, Laura Di Renzo and Antonino De Lorenzo

DOI: 10.2174/0929867326666190326113607

General Review Article

Role of microRNAs in chronic lymphocytic leukemia pathogenesis

, 2020; 27(2): 282-297.

Ehsan Javandoost, Ehsan Firoozi-Majd, Hosein Rostamian, Mohammad Khakpoor- Koosheh and Hamid Reza Mirzaei*

DOI: 10.2174/0929867326666190911114842

Review Article

Structural basis of drug recognition by human serum albumin

, 2020; 27(30): 4907-4931.

Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi

DOI: 10.2174/0929867326666190320105316

Most Accessed Articles

Recent Advances in c-Jun N-Terminal Kinase (JNK) Inhibitors

, 2021; 28(3): 607-627.

Gang Li, Wenqing Qi, Xiaoxun Li, Jinwu Zhao, Meihua Luo and Jianjun Chen*

DOI: 10.2174/0929867327666200210144114

Advances in L-Type Calcium Channel Structures, Functions and Molecular Modeling

, 2021; 28(3): 514-524.

Lei Xu*, Lilei Sun, Liangxu Xie, Shanzhi Mou, Dawei Zhang, Jingyu Zhu and Peng Xu*

DOI: 10.2174/0929867327666200714154059

Monoclonal Antibodies: A Prospective and Retrospective View

, 2021; 28(3): 435-471.

Jwala Sivaccumar*, Annamaria Sandomenico*, Luigi Vitagliano and Menotti Ruvo*

DOI: 10.2174/0929867327666200219142231

Recent Advances in the Development of Broad-Spectrum Antiprotozoal Agents

, 2021; 28(3): 583-606.

Antonio Moreno-Herrera, Sandra Cortez-Maya, Virgilio Bocanegra-Garcia, Bimal Krishna Banik and Gildardo Rivera*

DOI: 10.2174/0929867327666200303170000

Is Technical-Grade Chlordane an Obesogen?

, 2021; 28(3): 548-568.

Juliana F. Silva, Bruno P. Moreira, Luís Rato, Maria de Lourdes Pereira, Pedro F. Oliveira and Marco G. Alves*

DOI: 10.2174/0929867327666200121122208

Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy

, 2021; 28(2): 329-345.

Shunqin Zhu, Qin Yu, Chunsong Huo, Yuanpeng Li, Linshen He, Botian Ran, Ji Chen, Yonghao Li and Wanhong Liu*

DOI: 10.2174/0929867327666200121124404

Current Scenario and Future Prospect in the Management of COVID-19

, 2021; 28(2): 284-307.

Pobitra Borah, Pran Kishore Deb*, Satyendra Deka, Katharigatta N. Venugopala, Vinayak Singh, Raghu Prasad Mailavaram, Kiran Kalia and Rakesh Kumar Tekade*

DOI: 10.2174/0929867327666200908113642

Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids

, 2021; 28(2): 238-252.

Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo

DOI: 10.2174/0929867326666191029112626


Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
View Full Editorial Board

Nobel Laureates on Editorial Board

Prof. John Gurdon

Prof. Jean-Marie Lehn

Prof. Ferid Murad

COPE Compliant

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Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
Scopus CiteScore Metrics: 3.61

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