Bentham Science Logo

Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 16th of 59 in

    Chemistry & Medicinal

  • 67th of 261 in

    Pharmacology & Pharmacy

Order Your Article Before Print

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

,

Volume 25

-

Number 42



Editorial   Open Access



Current Frontiers   Open Access



Review Article



Review Article

A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues

, 25(42): 5822 - 5834

Alessia Carocci , Filomena Corbo , Giovanni Lentini , Maria Maddalena Cavalluzzi , Carlo Franchini and Alessia Catalano*


DOI: 10.2174/0929867325666180327104320


Review Article

Liver and Statins: A Critical Appraisal of the Evidence

, 25(42): 5835 - 5846

Anna Licata*, Antonina Giammanco, Maria Giovanna Minissale, Salvatore Pagano , Salvatore Petta and Maurizio Averna


DOI: 10.2174/0929867325666180327095441


Review Article



Review Article

Biologics for the Treatment of Juvenile Idiopathic Arthritis

, 25(42): 5860 - 5893

Dimitri Poddighe*, Micol Romano, Maurizio Gattinara and Valeria Gerloni


DOI: 10.2174/0929867325666180522085716


Review Article



Articles Ahead of Print

Inhibitors of ER Aminopeptidase 1 and 2: From Design to Clinical Application


Dimitris Georgiadis, Anastasia Mpakali, Despoina Koumantou and Efstratios Stratikos*


View Abstract View on PubMed



Therapeutic Options for Homozygous Familial Hypercholesterolemia: the Role of Lomitapide


Antonina Giammanco, Angelo B. Cefalù, Davide Noto and Maurizio R. Averna*


View Abstract View on PubMed


The Glycogen Synthase Kinase-3 in the Regulation of Ion Channels and Cellular Carriers


Mentor Sopjani, Lulzim Millaku, Dashnor Nebija, Merita Emini, Arleta Rifati-Nixha and Miribane Dermaku-Sopjani*


View Abstract View on PubMed


Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone


Cristina Agresti, Rosella Mechelli, Stefania Olla, Caterina Veroni, Cecilia Eleuteri, Giovanni Ristori and Marco Salvetti*


View Abstract View on PubMed


Editorial: Novel Therapeutic Strategies for the Treatment of Chronic Diseases


Gianluca Testa, Fabiana Passaro, Aldo Cinquegrana, Melania Palma, Pasquale Abete and Carlo Gabriele Tocchetti*





Endothelium as a Therapeutic Target in Diabetes Mellitus: From Basic Mechanisms to Clinical Practice


Anastasios Tentolouris, Ioanna Eleftheriadou, Evangelia Tzeravini, Dimitrios Tsilingiris, Stavroula A. Paschou, Gerasimos Siasos and Nikolaos Tentolouris*


View Abstract View on PubMed


How to Fluorescently Label the Potassium Channel: A Case in hERG


Xiaomeng Zhang, Beilei Wang, Zhenzhen Liu, Yubin Zhou and Lupei Du*


View Abstract View on PubMed


Management of Peripheral Neuropathy Induced by Chemotherapy


Maayan Fradkin*, Ron Batash*, Shiran Elamleh*, Ronen Debi , Pamela Schaffer , Moshe Schaffer and Noam Asna


View Abstract View on PubMed


Therapeutic Targeting of the Soluble Guanylate Cyclase


Garyfallia I Makrynitsa, Aikaterini A Zompra, Aikaterini I Argyriou, Georgios A Spyroulias and Stavros Topouzis*


View Abstract View on PubMed


Abstracts Ahead of Print


Recent Development on Anti-Obesity Compounds and Their Mechanisms of Action: A Review


Yixing Qiu, Huanghe Yu , Rong Zeng, Shiyin Guo, Muhammad Daniyal, Zeyu Deng, Aibing Wang and Wei Wang*


View Abstract




Metabolomic Biomarkers in Gynecology: a Treasure Path or a False Path?


Igor Govorov , Stanislav Sitkin , Tatyana Pervunina , Alexey Moskvin , Denis Baranenko and Eduard Komlichenko


View Abstract


Obesity therapy: how and why?


Sara Paccosi, Barbara Cresci, Laura Pala, Carlo Maria Rotella and Astrid Parenti*


View Abstract


Diabetic Cognitive Dysfunction: From Bench to Clinic


Jiyin Zhou, Zuo Zhang, Hongli Zhou and Guisheng Qian*


View Abstract


Outer Membrane Proteins of Salmonella As Potential Markers of Resistance to Serum, Antibiotics and Biocides


Bozena Futoma-Koloch, Gabriela Bugla-Płoskońska*, Bartłomiej Dudek, Agata Dorotkiewicz-Jach, Zuzanna Drulis-Kawa and Andrzej Gamian*


View Abstract



Cardioprotective Properties Of Hdl: Structural And Functional Considerations


E. Pappa, M. Elisaf, C. Kostara, E. Bairaktari and V. Tsimihodimos*


View Abstract


Open Access Articles

Mycosporine-Like Amino Acids for Skin Photoprotection

, 2018; 25(40): 5512 - 5527

Karl P. Lawrence, Paul F. Long and Antony R. Young*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25(35): 4638 - 4652

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*




Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

, 2018; 25(35): 4616 - 4637

Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*




Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*





NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment

, 2018; 25(3): 404 - 432

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *





Lipids as Biomarkers of Cancer and Bacterial Infections

, 2018; 25: 1 - 9 (E-Pub Ahead of Print)

Gerald Larrouy-Maumus *




Immunocontraception: Filamentous Bacteriophage as a Platform for Vaccine Development

, 2017; 24(35): 3907 - 3920

Tatiana I. Samoylova*, Timothy D. Braden, Jennifer A. Spencer and Frank F. Bartol




A Therapeutic Connection between Dietary Phytochemicals and ATP Synthase

, 2017; 24(35): 3894 - 3906

Zulfiqar Ahmad*, Sherif S. Hassan and Sofiya Azim





Major Developments in the Design of Inhibitors along the Kynurenine Pathway

, 2017; 24(23): 2471 - 2495

Kelly R. Jacobs, Gloria Castellano-Gonzalez , Gilles J. Guillemin * and David B. Lovejoy *






Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2017; 24: 1 - 12 (E-Pub Ahead of Print)

Renata Bujak, Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndle, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*





Most Cited Articles

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

, 2016; 23(36): 4135-4150.

Hamed Mirzaei, Sara Khataminfar, Saeid Mohammadparast, Soudabeh Shahid Sales, Mina Maftouh, Mohsen Mohammadi, Miganoosh Simonian, Seyed Mohammd Reza Parizadeh, Seyed Mahdi Hassanian and Amir Avan


DOI: 10.2174/0929867323666160818093854





MicroRNAs: Key Players in Microglia and Astrocyte Mediated Inflammation in CNS Pathologies

, 2016; 23(30): 3528-3546.

Aparna Karthikeyan, Radhika Patnala, Shweta P. Jadhav, Ling Eng-Ang and S. Thameem Dheen


DOI: 10.2174/0929867323666160814001040


Adamantane – A Lead Structure for Drugs in Clinical Practice

, 2016; 23(29): 3245-3266.

Katarina Spilovska, Filip Zemek, Jan Korabecny, Eugenie Nepovimova, Ondrej Soukup, Manfred Windisch and Kamil Kuca


DOI: 10.2174/0929867323666160525114026


Application of Mesenchymal Stem Cells in Melanoma: A Potential Therapeutic Strategy for Delivery of Targeted Agents

, 2016; 23(5): 455-463.

Hamed Mirzaei, Amirhossein Sahebkar, Amir Avan, Mahmoud R. Jaafari, Rasoul Salehi, Hossein Salehi, Hossein Baharvand, Abbas Rezaei, Jamshid Hadjati, John M. Pawelek and Hamid R. Mirzaei


DOI: 10.2174/0929867323666151217122033


Morin: A Promising Natural Drug

, 2016; 23(8): 774-791.

Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli


DOI: 10.2174/0929867323666160106150821


Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy

, 2016; 23(30): 3450-3480.

Francesco Moccia, Estella Zuccolo, Valentina Poletto, Ilaria Turin, Germano Guerra, Paolo Pedrazzoli, Vittorio Rosti, Camillo Porta and Daniela Montagna


DOI: 10.2174/0929867323666160607111220




Most Accessed Articles

Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Peptide-Drug Conjugate: A Novel Drug Design Approach

, 2017; 24(31): 3373-3396.

Liang Ma, Chao Wang, Zihao He, Biao Cheng, Ling Zheng and Kun Huang*


DOI: 10.2174/0929867324666170404142840


Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756


Phosphodiesterase 10 Inhibitors - Novel Perspectives for Psychiatric and Neurodegenerative Drug Discovery

, 2018; 25(29): 3455-3481.

Agnieszka Zagorska*, Anna Partyka, Adam Bucki, Alicja Gawalskax, Anna Czopek and Maciej Pawlowski


DOI: 10.2174/0929867325666180309110629




Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review

, 2017; 24(27): 3002-3009.

Ron Batash , Noam Asna *, Pamela Schaffer, Nicole Francis and Moshe Schaffer


DOI: 10.2174/0929867324666170516123206


Fc-fusion Proteins in Therapy: An Updated View

, 2017; 24(12): 1228-1237.

Reza Jafari, Naime M. Zolbanin, Houshang Rafatpanah, Jafar Majidi and Tohid Kazemi*


DOI: 10.2174/0929867324666170113112759


Multi-Target Directed Drugs as a Modern Approach for Drug Design Towards Alzheimer’s Disease: An Update

, 2018; 25(29): 3491-3525.

Matheus de Freitas Silva, Kris Simone Tranches Dias, Vanessa Silva Gontijo, Cindy Juliet Cristancho Ortiz and Claudio Viegas Jr.*


DOI: 10.2174/0929867325666180111101843



Related Journals

Related eBooks

eBooks Catalog