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Current Medicinal Chemistry

Volume 26, 42 Issues, 2019
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 103th of 293 in

    Biochemistry & Molecular Biology

  • 16th of 59 in

    Chemistry, Medicinal

  • 67th of 261 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

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Volume 26

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Number 9



Biography   Open Access



Editorial   Open Access



Review Article



Review Article

Lipoproteins in Atherosclerosis Process

, 26(9): 1525 - 1543

Valentina Arnao, Antonino Tuttolomondo*, Mario Daidone and Antonio Pinto


DOI: 10.2174/0929867326666190516103953


Review Article



Review Article



Review Article



Review Article

Dysfunctional HDL as a Therapeutic Target for Atherosclerosis Prevention

, 26(9): 1610 - 1630

Alice Ossoli, Chiara Pavanello, Eleonora Giorgio, Laura Calabresi and Monica Gomaraschi*


DOI: 10.2174/0929867325666180316115726


Articles Ahead of Print


Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes


José M. Matés*, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Juan A. Segura, Francisco J. Alonso and Javier Márquez


View Abstract View on PubMed


Tear Inflammatory Molecules in Contact Lens Wearers: A Literature Review


Alberto López-dela Rosa, María J González-García, Margarita Calonge* and Amalia Enríquez-de-Salamanca


View Abstract View on PubMed




Selective MMP-13 Inhibitors: Promising Agents for the Therapy of Osteoarthritis


Yichao Wan*, Wei Li, Zhipeng Liao, Mi Yan, Xuwang Chen* and Zilong Tang


View Abstract View on PubMed


Recent Advances of Chitosan and Its Derivatives in Biomedical Applications


Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao and Yongmin Zhang*


View Abstract View on PubMed



Therapeutic applications of Peptides Against Zika Virus: A Review


Preeti Karwal, Ishwar Dutt Vats, Niharika Sinha, Anchal Singhal, Teena Sehgal and Pratibha Kumari*


View Abstract View on PubMed


Obesity and Body Composition in Man and Woman: Associated Diseases and the New Role of Gut Microbiota


Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Laura Di Renzo and Antonino De Lorenzo


View Abstract View on PubMed


Abstracts Ahead of Print


Anti-Inflammatory Properties of Plant Derived Natural Products – A Systematic Review


Iris Allijn, René P Brinkhuis, Gert Storm and Raymond Schiffelers*


View Abstract


Management of patients with heart failure: focus on new pharmaceutical and device options


Alexandros Briasoulis*, Chakradhari Inampudi, Georgios Hatzis and Rabea Asleh


View Abstract


Biased agonism as an emerging strategy in the search for better opioid analgesics


Justyna Piekielna-Ciesielska, Karol Wtorek and Anna Janecka*


View Abstract



B7-H3 immune checkpoint protein in human cancer


Karine Flem-Karlsen, Oystein Fodstad and Caroline E. Nunes-Xavier*


View Abstract


Immunoliposomes in acute myeloid leukaemia therapy. An overview of possible targets and obstacles


Aditi Singh, Nikolai Norevik Myklebust, Sarah Marie Vie Furevik, Ragnhild Haugse and Lars Herfindal*


View Abstract



Tear Film, Conjunctival and Corneal Modifications Induced by Glaucoma Treatment


Gloria Roberti*, Lucia Tanga, Gianluca Manni, Ivano Riva, Alice Chandra Verticchio, Francesca Berardo, Carmela Carnevale and Francesco Oddone


View Abstract


The Structures and Bioactivities of Fatty Acid Synthase Inhibitors


Hezhong Jiang , Tian Gan , Jiasui Zhang , Qingyun Ma , Yan Liang* and Youxing Zhao*


View Abstract


Published Contents

Open Access Articles

Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*




Carbohydrate Scaffolds for the Study of the Autism-associated Bacterium, Clostridium bolteae

, 2019; 26: 1 - 7 (E-Pub Ahead of Print)

Brittany Pequegnat and Mario Artur Monteiro*




The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease

, 2018; 25(40): 5578 - 5587

Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen*




Mycosporine-Like Amino Acids for Skin Photoprotection

, 2018; 25(40): 5512 - 5527

Karl P. Lawrence, Paul F. Long and Antony R. Young*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25(35): 4638 - 4652

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*




Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

, 2018; 25(35): 4616 - 4637

Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*




Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*





NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment

, 2018; 25(3): 404 - 432

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *





Lipids as Biomarkers of Cancer and Bacterial Infections

, 2018; 25: 1 - 9 (E-Pub Ahead of Print)

Gerald Larrouy-Maumus *




Immunocontraception: Filamentous Bacteriophage as a Platform for Vaccine Development

, 2017; 24(35): 3907 - 3920

Tatiana I. Samoylova*, Timothy D. Braden, Jennifer A. Spencer and Frank F. Bartol




A Therapeutic Connection between Dietary Phytochemicals and ATP Synthase

, 2017; 24(35): 3894 - 3906

Zulfiqar Ahmad*, Sherif S. Hassan and Sofiya Azim





Major Developments in the Design of Inhibitors along the Kynurenine Pathway

, 2017; 24(23): 2471 - 2495

Kelly R. Jacobs, Gloria Castellano-Gonzalez , Gilles J. Guillemin * and David B. Lovejoy *





Most Cited Articles


Review Article

Immune checkpoint inhibitors and cardiac toxicity: An emerging issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Review Article

Effects of polyphenolic derivatives on heme oxygenase-system in metabolic dysfunctions

, 1 January 2018; 25(13): 1577-1595.

Valeria Pittala*, Luca Vanella, Loredana Salerno, Giuseppe Romeo, Agostino Marrazzo, Claudia Di Giacomo and Valeria Sorrenti


DOI: 10.2174/0929867324666170616110748


Review Article

Structure, function, involvement in diseases and targeting of 14-3-3 proteins: An Update

, 2018; 25(1): 5-21.

Ylenia Cau, Daniela Valensin, Mattia Mori, Sara Draghi and Maurizio Botta*


DOI: 10.2174/0929867324666170426095015


Review Article

Alzheimer's disease: A review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126


Review Article

Bisphenol a in reproduction: Epigenetic effects

, 1 January 2018; 25(6): 748-770.

Rosanna Chianese, Jacopo Troisi, Sean Richards, Marika Scafuro , Silvia Fasano, Maurizio Guida , Riccardo Pierantoni and Rosaria Meccariello*


DOI: 10.2174/0929867324666171009121001


Review Article

Hydroxypyridinone derivatives: A fascinating class of chelators with therapeutic applications - An update

, 2018; 25(1): 97-112.

Sílvia Chaves, Luca Piemontese, Asha Hiremathad and M. Amélia Santos*


DOI: 10.2174/0929867324666170330092304


Review Article

Carboxylesterase inhibitors: An update

, 2018; 25(14): 1627-1649.

Li-Wei Zou , Qiang Jin, Dan-Dan Wang, Qing-Kai Qian, Da-Cheng Hao, Guang-Bo Ge* and Ling Yang


DOI: 10.2174/0929867325666171204155558


Review Article

Mycosporine-like amino acids for skin photoprotection

, 2018; 25(40): 5512-5527.

Karl P. Lawrence, Paul F. Long and Antony R. Young*


DOI: 10.2174/0929867324666170529124237


Review Article

New perspectives on biomedical applications of iron oxide nanoparticles

, 1 January 2018; 25(4): 540-555.

Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de A. Roger and Fabio Vianello*


DOI: 10.2174/0929867324666170616102922


Review Article

Bioactive metabolites from pathogenic and endophytic fung i of forest trees

, 2018; 25(2): 208-252.

Marco Masi, Lucia Maddau, Benedetto Teodoro Linaldeddu, Bruno Scanu , Antonio Evidente and Alessio Cimmino*


DOI: 10.2174/0929867324666170314145159


Review Article

Ngs technologies as a turning point in rare disease resea rch , diagnosis and treatment

, 1 January 2018; 25(3): 404-432.

Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *


DOI: 10.2174/0929867324666170718101946


Review Article

Immunotherapeutic interleukin-6 or interleukin-6 receptor blockade in cancer: Challenges and opportunities

, 2018; 25(36): 4785-4806.

Nirmala Chandralega Kampan, Sue D. Xiang, Orla M. McNally, Andrew N. Stephens, Michael A. Quinn and Magdalena Plebanski*


DOI: 10.2174/0929867324666170712160621


Review Article

Targeting cancer stem cells for chemoprevention of pancreatic cancer

, 2018; 25(22): 2585-2594.

Dharmalingam Subramaniam, Gaurav Kaushik, Prasad Dandawate and Shrikant Anant*


DOI: 10.2174/0929867324666170127095832




Most Accessed Articles

Fc-fusion Proteins in Therapy: An Updated View

, 2017; 24(12): 1228-1237.

Reza Jafari, Naime M. Zolbanin, Houshang Rafatpanah, Jafar Majidi and Tohid Kazemi*


DOI: 10.2174/0929867324666170113112759


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue

, 2018; 25(11): 1327-1339.

Gilda Varricchi*, Giancarlo Marone, Valentina Mercurio, Maria Rosaria Galdiero, Domenico Bonaduce and Carlo G. Tocchetti*


DOI: 10.2174/0929867324666170407125017


Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review

, 2017; 24(27): 3002-3009.

Ron Batash , Noam Asna *, Pamela Schaffer, Nicole Francis and Moshe Schaffer


DOI: 10.2174/0929867324666170516123206


Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer

, 2017; 24(12): 1170-1185.

Matteo Vergati, Eriseld Krasniqi, Girolamo D. Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni* and Mario Roselli


DOI: 10.2174/0929867324666170116122915


Peptide-Drug Conjugate: A Novel Drug Design Approach

, 2017; 24(31): 3373-3396.

Liang Ma, Chao Wang, Zihao He, Biao Cheng, Ling Zheng and Kun Huang*


DOI: 10.2174/0929867324666170404142840


Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases

, 2018; 25(32): 3930-3952.

Roberto Russo*, Claudia Cristiano, Carmen Avagliano, Carmen De Caro, Giovanna La Rana, Giuseppina Mattace Raso, Roberto Berni Canani, Rosaria Meli and Antonio Calignano


DOI: 10.2174/0929867324666170216113756



Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment

, 2018; 25(26): 3141-3159.

Leide Caroline dos Santos Picanco*, Priscilla F. Ozela, Maiara de Fatima de Brito Brito, Abraao A. Pinheiro, Elias C. Padilha, Francinaldo S. Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín M.C. Rosa and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/0929867323666161213101126



Development of Bruton’s Tyrosine Kinase Inhibitors for Rheumatoid Arthritis

, 2018; 25(42): 5847-5859.

Jiahui Lv, Jingde Wu*, Feng He, Ying Qu, Qiuqiong Zhang and Chenggong Yu


DOI: 10.2174/0929867325666180316121951



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