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Current Enzyme Inhibition

Volume 18, 3 Issues, 2022
ISSN: 1875-6662 (Online)
ISSN: 1573-4080 (Print)
This journal supports open access

Aims & Scope

Current Enzyme Inhibition aims to publish original research, full-length/mini review and letter articles in all the latest and outstanding developments on enzyme inhibition studies. The coverage includes the mechanisms of inhibitory processes of enzymes, recognition of active sites, and the discovery of agonists and antagonists, leading to the design and development of new drugs of significant therapeutic value. Current Enzyme Inhibition is an essential journal for every pharmaceutical researcher and medicinal chemist who wishes to have up-to-date knowledge about each and every development in the study of enzyme inhibition.

Current Enzyme Inhibition

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Volume 18

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Number 1




Research Article

Ovine COX-1 Isoenzyme Bio-production

, 18(1): 2 - 9

Morena Miciaccia, Mariaclara Iaselli, Savina Ferorelli, Paola Loguercio Polosa, Maria Grazia Perrone* and Antonio Scilimati*


DOI: 10.2174/1573408017666211108104731


Research Article

A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition

, 18(1): 10 - 18

Maria Grazia Perrone, Morena Miciaccia, Savina Ferorelli and Antonio Scilimati*


DOI: 10.2174/1573408018666220204104612


Research Article

New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway

, 18(1): 19 - 31

Jhoan H. Piermattey, Maicol Ahumedo, Yvonne Heuze, Juan Soriano and Marisa Cabeza*


DOI: 10.2174/1573408018666220106151712



Research Article





Articles Ahead of Print

L-Proline Catalyzed Knoevenagel Condensation of Aldehydes with Active Methylene Compounds and Their Molecular Modeling Studies for Anti- SARS CoV-2 Potentials


Bapu R Thorat*, Dnyaneshwar T Nagre, Pawan P Dhurandhar, Pratiksha K. Borase, Sweta Bavkar, Riddhi R. Kasar, Rohan D Narkar, Mazhar Farooqui and Suraj N. Mali


DOI: 10.2174/1573408018666220516104525
View Abstract


Recent PARP Inhibitor Advancements in Cancer Therapy: A Review


Pulla Prudvi Raj, Kaviarasan Lakshmanan, Gowramma Byran*, Kalirajan Rajagopal, Praveen Thaggikuppe Krishnamurthy and Divya Jyothi Palati


DOI: 10.2174/1573408018666220321115033
View Abstract






Alpha-glucosidase and Alpha-amylase Inhibition Activity of Avocado Fruit of Nepalese Origin


Kamal Dhakal, Dipesh Shrestha, Tamlal Pokhrel, Devi Prasad Bhandari and Achyut Adhikari*


DOI: 10.2174/1573408018666220324110300
View Abstract




Abstracts Ahead of Print







Antioxidant and tyrosinase inhibitory activities of A. sicula L. aqueous extract


Karima Loucif*, Fatima Benchikh, Hassiba Benabdallah, Chawki Bensouici and Smain Amira


DOI: 10.2174/1573408018666220322163312
View Abstract


Published Contents

Editor's Choice

Molecular Docking Demonstration of the Liquorice Chemical Molecules on the Protease and ACE2 of COVID-19 Virus

, 2021; 17(2): 98 - 110

İsmail Koyuncu*, Mustafa Durgun, Nuri Yorulmaz, Sahin Toprak, Ataman Gonel, Nihayet Bayraktar and Murat Caglayan


DOI: 10.2174/1573408016999201228193118



Relationship with Metalloproteinase 13, E-cadherin, Homocysteine and Co Factors Folic Acid and Vitamin B12 in Patients Diagnosed with Prostate Cancer

, 2021; 17(1): 33 - 41

Thaís M. Gascón*, Beatriz G. Lourenço, Edimar C. Pereira, Beatriz A. da Costa Aguiar, Glaucia L. Veiga, Flavia de Sousa Gehrke, Fernando Adami and Fernando L.A. Fonseca


DOI: 10.2174/1573408016999201026195354








Vigna unguiculata Trypsin Inhibitor: A Protein with Versatile Biological Applications

, 2018; 14(1): 75 - 84

Romana Parveen, Tooba Naz Shamsi, Sumbul Afreen, Mudsser Azam, Tasneem Fatma, Qazi Mohd. Rizwanul Haque and Sadaf Fatima*


DOI: 10.2174/1573408013666170619085504



Molecular Insight and Binding Pattern Analysis of Shikonin as a Potential VEGFR-2 Inhibitor

, 2017; 13(3): 235 - 244

Raju Dash, Md. Junaid, Nazrul Islam, Md. Forhad Chowdhury Akash, Md. Imran Khan, Md. Arifuzzaman, Mahmuda Khatun and S. M. Zahid Hosen*


DOI: 10.2174/1573408013666161227162452



Overview of the Structure and Function of Protein Kinases

, 2017; 13(2): 81 - 88

Sugunadevi Sakkiah, Guang Ping Cao, Staya P. Gupta and Keun Woo Lee*


DOI: 10.2174/1573408013666161226155608



Open Access Articles

Effects of N224 Glycosylation in Saccharomycopsis fibuligera R64 α-Amylase on Enzyme Activity and Stability

, 2021; 17(3): 188 - 195

Yovin Sugijo, Tina Dewi Rosahdi, Fernita Puspasari, Wangsa Tirta Ismaya, Khomaini Hasan, Ihsanawati, Toto Subroto and Dessy Natalia*




Inhibition by Substrates of a Coniferyl Alcohol Dehydrogenase Purified from Sugarcane Stalks

, 2019; 15(3): 206 - 214

Borja Alarcón, Roberto de Armas, Carlos Vicente and María E. Legaz*








Most Cited Articles

Systemic Review Article

Should olanzapine be advocated over conventional anti-emetics for the prevention of chemotherapy-induced nausea and vomiting? An updated meta-analysis of randomized control trials

, 2019; 15(2): 80-90.

Eshak Ibrahim Bahbah*, Ahmed Ramadan Abdalla, Khalid Abdelshafy, Ahmed Diaa Almohandes , Amr Menshawy, Mohamed Abd Elalem Aziz, Mahmoud Ahmed Ebada, Awad Hegab and Ahmed Negida*


DOI: 10.2174/1573408015666190620165507


Research Article

In vitro inhibition effect and molecular docking study of curcumin, resveratrol, and quercetin on human erythrocyte glutathione transferase

, 2019; 15(3): 197-205.

Mine Aksoy*, Muhammet Karaman, Pınar Güller, Uğur Güller and Ö. İrfan Küfrevioğlu


DOI: 10.2174/1573408016666191231123544



Review Article

A brief review on dual target of PARP1 and STAT3 for cancer therapy: A novel perception

, 2020; 16(2): 115-134.

Kaviarasan Lakshmanan, Gowramma Byran* and Manal Mohammed


DOI: 10.2174/1573408016666200316114209


Review Article

Recent studies on HDAC inhibitors acting against prostate cancer

, 2020; 16(1): 74-89.

Basheerulla Shaik*, Tabassum Zafar and Satya P. Gupta


DOI: 10.2174/1573408016666200402092557



Research Article

Synthesis and pancreatic lipase inhibitory activity of phenacyl esters of N-aroyl amino acids

, 2019; 15(2): 133-143.

Maida Engels Selvaraj Emimmal and Veintramuthu Sankar*


DOI: 10.2174/1573408015666190920092114


Research Article

Enzyme inhibition, kinetic, and molecular docking studies of α-glucosidase

, 2020; 16(2): 155-161.

Ebrahim S. Moghadam, Mohammad A. Faramarzi, Somayeh Imanparast and Mohsen Amini*


DOI: 10.2174/1573408016999200415115009




Review Article

Role of cytochrome P450 in prostate cancer and its therapy

, 2020; 16(1): 63-73.

Rishabh Kaushik, Sheeza Khan, Meesha Sharma, Srinivasan Hemalatha, Zeba Mueed and Nitesh K. Poddar*


DOI: 10.2174/1573408016666200218122044


Research Article

Molecular docking demonstration of the liquorice chemical molecules on the protease and ace2 of covid-19 virus

, 2021; 17(2): 98-110.

İsmail Koyuncu*, Mustafa Durgun, Nuri Yorulmaz, Sahin Toprak, Ataman Gonel, Nihayet Bayraktar and Murat Caglayan


DOI: 10.2174/1573408016999201228193118


Letter Article

Unprecedented role of the N73-F124 pair in the staphylococcus equorum MnSOD activity

, 2021; 17(1): 2-8.

Debbie S. Retnoningrum*, Hiromi Yoshida, Muthia D. Razani, Vincencius F. Meidianto, Andrian Hartanto, Anita Artarini and Wangsa T. Ismaya


DOI: 10.2174/1573408016999201027212952



Research Article

Pharmacological and in-silico investigations of anxiolytic-like effects of phyllanthus fraternus: A probable involvement of gaba-a receptor

, 2021; 17(1): 42-48.

Atul R. Chopade*, Rahul P. Pol, Pramod A. Patil, Vyankatesh R. Dharanguttikar, Nilofar S. Naikwade, Remeth J. Dias and Suraj N. Mali


DOI: 10.2174/1573408016999201026200650



Most Accessed Articles


Molecular Docking Demonstration of the Liquorice Chemical Molecules on the Protease and ACE2 of COVID-19 Virus

, 2021; 17(2): 98-110.

İsmail Koyuncu*, Mustafa Durgun, Nuri Yorulmaz, Sahin Toprak, Ataman Gonel, Nihayet Bayraktar and Murat Caglayan


DOI: 10.2174/1573408016999201228193118




Laurus Nobilis Linn. Inhibits Polyol Pathway Enzymes: Strategy for Managing Diabetic Complications

, 2021; 17(2): 120-126.

Habeeb Adebodun Bankole, Azeez Ayomide Fatai, Sulihat Motunrayo Aleshe, Mutiu Idowu Kazeem* and Abidemi Paul Kappo


DOI: 10.2174/1573408017666210223124126



Investigation of the Effect of Loratadine and Calcium Ions on Oxidoreductase Activity of Catalase Enzyme

, 2021; 17(1): 26-32.

Edhem Hasković, Safija Herenda*, Zehra Halilović, Snežana Unčanin, Denis Hasković and Ena Deljkić


DOI: 10.2174/1573408016999200817173859



Unprecedented Role of the N73-F124 Pair in the Staphylococcus equorum MnSOD Activity

, 2021; 17(1): 2-8.

Debbie S. Retnoningrum*, Hiromi Yoshida, Muthia D. Razani, Vincencius F. Meidianto, Andrian Hartanto, Anita Artarini and Wangsa T. Ismaya


DOI: 10.2174/1573408016999201027212952




Pharmacological and In-Silico Investigations of Anxiolytic-like Effects of Phyllanthus Fraternus: A Probable Involvement of GABA-A Receptor

, 2021; 17(1): 42-48.

Atul R. Chopade*, Rahul P. Pol, Pramod A. Patil, Vyankatesh R. Dharanguttikar, Nilofar S. Naikwade, Remeth J. Dias and Suraj N. Mali


DOI: 10.2174/1573408016999201026200650




Relationship with Metalloproteinase 13, E-cadherin, Homocysteine and Co Factors Folic Acid and Vitamin B12 in Patients Diagnosed with Prostate Cancer

, 2021; 17(1): 33-41.

Thaís M. Gascón*, Beatriz G. Lourenço, Edimar C. Pereira, Beatriz A. da Costa Aguiar, Glaucia L. Veiga, Flavia de Sousa Gehrke, Fernando Adami and Fernando L.A. Fonseca


DOI: 10.2174/1573408016999201026195354



Editor-in-Chief

graphic
Claudiu T. Supuran
(90591 citations)
Neurofarba Department
University of Florence
Florence
(Italy)
Biography
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