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Current Drug Metabolism

Volume 21, 14 Issues, 2020
ISSN: 1875-5453 (Online)
ISSN: 1389-2002 (Print)
This journal supports open access

Ranking and Category

  • 200th of 298 in

    Biochemistry & Molecular Biology

  • 158th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism, pharmacokinetics, and drug disposition. The journal serves as an international forum for the publication of full-length/mini review, research articles and guest edited issues in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the most important developments. The journal covers the following general topic areas: pharmaceutics, pharmacokinetics, toxicology, and most importantly drug metabolism.

More specifically, in vitro and in vivo drug metabolism of phase I and phase II enzymes or metabolic pathways; drug-drug interactions and enzyme kinetics; pharmacokinetics, pharmacokinetic-pharmacodynamic modeling, and toxicokinetics; interspecies differences in metabolism or pharmacokinetics, species scaling and extrapolations; drug transporters; target organ toxicity and interindividual variability in drug exposure-response; extrahepatic metabolism; bioactivation, reactive metabolites, and developments for the identification of drug metabolites. Preclinical and clinical reviews describing the drug metabolism and pharmacokinetics of marketed drugs or drug classes.

Current Drug Metabolism

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Volume 20

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Number 14



Biography   Open Access



Editorial   Open Access



Review Article (Mini-Review)



Review Article (Mini-Review)

Effect of Environmental Exposure and Pharmacogenomics on Drug Metabolism

, 20(14): 1103 - 1113

Basu Dev Banerjee*, Ranjeet Kumar, Krishna Latha Thamineni, Harendra Shah, Gaurav Kumar Thakur and Tusha Sharma


DOI: 10.2174/1389200221666200110153304


Review Article



Review Article



Review Article



Review Article



Abstracts Ahead of Print

Tubulin Proteins in Cancer Resistance: A review


Mohammad A. Kamal, Maryam H. Al-Zahrani, Salman Hasan Khan, Mateen Hasan Khan, Hani Awad Al Subhi, Abudukadeer Kuerban , Muhammad Aslam, Fahad A. Al Abassi and Firoz Anwar*


DOI: 10.2174/1389200221666200226123638
View Abstract


Clinical Impact of Co-Medication of Levetiracetam and Clobazam with Proton Pump Inhibitors: A Drug Interaction Study


Bhuvanachandra Pasupuleti, Vamshikrishna Gone*, Ravali Baddam, Raj Kumar Venisetty and Om Prakash Prasad


DOI: 10.2174/1389200221666200218121050
View Abstract


Stem Cells in Tumour Microenvironment Aids for Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment


Bhaskar Birru, ChandraSai Potla Durthi*, Santhosh Kacham, Madhuri Pola, Satish Babu Rajulapati, Sreenivasa Rao Parcha and Mohammad Amjad Kamal


DOI: 10.2174/1389200221666200214120226
View Abstract



Published Contents

Editor's Choice

Effect of Environmental Exposure and Pharmacogenomics on Drug Metabolism

, 2019; 20(14): 1103 - 1113

Basu Dev Banerjee*, Ranjeet Kumar, Krishna Latha Thamineni, Harendra Shah, Gaurav Kumar Thakur and Tusha Sharma


DOI: 10.2174/1389200221666200110153304



Therapeutic Study of Phytochemicals Against Cancer and Alzheimer’s Disease Management

, 2019; 20(13): 1006 - 1013

Syed Sayeed Ahmad, Tayyaba Waheed, Sayed Rozeen, Sufia Mahmood and Mohammad Amjad Kamal*


DOI: 10.2174/1389200221666200103092719



A Retrospective Look at Anti-EGFR Agents in Pancreatic Cancer Therapy

, 2019; 20(12): 958 - 966

Henu K. Verma, Praveen K. Kampalli, Saikrishna Lakkakula, Gayathri Chalikonda, Lakkakula V.K.S. Bhaskar* and Smaranika Pattnaik*


DOI: 10.2174/1389200220666191122104955




Assessment of miR-212 and Other Biomarkers in the Diagnosis and Treatment of HBV-infection-related Liver Diseases

, 2019; 20(10): 785 - 798

Yigan Zhang, Huaze Xi, Xin Nie, Peng Zhang, Ning Lan, Ying Lu, Jinrong Liu and Wenzhen Yuan*


DOI: 10.2174/1389200220666191011120434




Influence of the OATP Polymorphism on the Population Pharmacokinetics of Methotrexate in Chinese Patients

, 2019; 20(7): 592 - 600

Zhiqi Wang, Nan Zhang, Chaoyang Chen, Shuqing Chen, Junyu Xu, Ying Zhou, Xia Zhao* and Yimin Cui*


DOI: 10.2174/1389200220666190701094756



Interethnic Variations of UGT1A1 and UGT1A7 Polymorphisms in the Jordanian Population

, 2019; 20(5): 399 - 410

Sara Abudahab*, Nancy Hakooz, Yazun Jarrar, Mohammad Al Shahhab, Ahmad Saleh, Malek Zihlif and Rana Dajani


DOI: 10.2174/1389200220666190528085151



Effects of CYP2C8 and SLCO1B1 Genetic Polymorphisms on Repaglinide Pharmacokinetics: A Systematic Review and Meta-Analysis

, 2019; 20(4): 266 - 274

Shuang Zhou, Qian Xiang, Guangyan Mu, Lingyue Ma, Shuqing Chen, Qiufen Xie, Zhuo Zhang and Yimin Cui*


DOI: 10.2174/1389200220666190111114146




Open Access Articles

Dysregulation of lncRNA and circRNA Expression in Mouse Testes after Exposure to Triptolide

, 2019; 20(8): 665 - 673

Suping Xiong, Yanting Li, Yang Xiang, Na Peng, Chunmiao Shen, Yanqiu Cai, Dandan Song, Peng Zhang, Xiaolong Wang, Xuihui Zeng and Xiaoning Zhang*




Influence of the OATP Polymorphism on the Population Pharmacokinetics of Methotrexate in Chinese Patients

, 2019; 20(7): 592 - 600

Zhiqi Wang, Nan Zhang, Chaoyang Chen, Shuqing Chen, Junyu Xu, Ying Zhou, Xia Zhao* and Yimin Cui*




Decreased Disposition of Anticancer Drugs Predominantly Eliminated via the Liver in Patients with Renal Failure

, 2019; 20(5): 361 - 376

Ken-ichi Fujita *, Natsumi Matsumoto, Hiroo Ishida, Yutaro Kubota, Shinichi Iwai, Motoko Shibanuma and Yukio Kato




Effects of CYP2C8 and SLCO1B1 Genetic Polymorphisms on Repaglinide Pharmacokinetics: A Systematic Review and Meta-Analysis

, 2019; 20(4): 266 - 274

Shuang Zhou, Qian Xiang, Guangyan Mu, Lingyue Ma, Shuqing Chen, Qiufen Xie, Zhuo Zhang and Yimin Cui*






Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model

, 2019; 20(2): 103 - 113

Shotaro Uehara, Toru Oshio, Kazuyuki Nakanishi, Etsuko Tomioka, Miyu Suzuki, Takashi Inoue, Yasuhiro Uno, Erika Sasaki and Hiroshi Yamazaki*





Thiazide Therapy in Chronic Kidney Disease: Renal and Extra Renal Targets

, 2018; 19(12): 1012 - 1020

Negiin Pourafshar*, Saeed Alshahrani, Ashkan Karimi and Manoocher Soleimani*




Models of Drug Induced Liver Injury (DILI) – Current Issues and Future Perspectives

, 2018; 19(10): 830 - 838

Lucija Kuna, Ivana Bozic, Tomislav Kizivat, Kristina Bojanic, Margareta Mrso, Edgar Kralj, Robert Smolic, George Y. Wu and Martina Smolic*






Digestive Enzyme Supplementation in Gastrointestinal Diseases

, 2016; 17(2): 187 - 193

Gianluca Ianiro, Silvia Pecere, Valentina Giorgio, Antonio Gasbarrini and Giovanni Cammarota




Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines

, 2015; 16(6): 412 - 426

Derek W. Edwardson, Rashmi Narendrula, Simon Chewchuk, Kyle Mispel-Beyer, Jonathan P.J. Mapletoft and Amadeo M. Parissenti




Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide

, 2014; 15(10): 953 - 965

Mario Cozzolino, Felix Funk, Viatcheslav Rakov, Olivier Phan and Isaac Teitelbaum





Most Cited Articles

Review Article

Survey of machine learning techniques in drug discovery

, 2019; 20(3): 185-193.

Natalie Stephenson, Emily Shane, Jessica Chase, Jason Rowland, David Ries, Nicola Justice, Jie Zhang, Leong Chan and Renzhi Cao*


DOI: 10.2174/1389200219666180820112457



Review Article

Recent advances in machine learning methods for predicting heat shock proteins

, 2019; 20(3): 224-228.

Wei Chen*, Pengmian Feng, Tao Liu and Dianchuan Jin


DOI: 10.2174/1389200219666181031105916



Review Article

Survey of machine learning techniques for prediction of the isoform specificity of cytochrome P450 substrates

, 2019; 20(3): 229-235.

Yi Xiong, Yanhua Qiao, Daisuke Kihara, Hui-Yuan Zhang, Xiaolei Zhu* and Dong-Qing Wei*


DOI: 10.2174/1389200219666181019094526


Review Article

Magnetic nanoparticles: Current trends and future aspects in diagnostics and nanomedicine

, 2019; 20(6): 457-472.

Naga Veera Srikanth Vallabani, Sanjay Singh* and Ajay Singh Karakoti*


DOI: 10.2174/1389200220666181122124458




Review Article

Iron oxide nanoparticles for breast cancer theranostics

, 2019; 20(6): 446-456.

Md. Salman Shakil, Md. Ashraful Hasan* and Satya Ranjan Sarker*


DOI: 10.2174/1389200220666181122105043



Review Article

Genitourinary tumors: Update on molecular biomarkers for diagnosis, prognosis and prediction of response to therapy

, 2019; 20(4): 305-312.

Alessia Cimadamore, Marina Scarpelli, Matteo Santoni, Francesco Massari, Francesca Tartari, Roy Cerqueti, Antonio Lopez-Beltran, Liang Cheng and Rodolfo Montironi*


DOI: 10.2174/1389200220666190225124352


General Review Article

Iron and Vitamin D/Calcium deficiency after gastric bypass: Mechanisms involved and strategies to improve oral supplement disposition

, 2019; 20(3): 244-252.

Aisling Mangan*, Carel W. Le Roux, Nana Gletsu Miller and Neil G. Docherty


DOI: 10.2174/1389200219666181026160242


Review Article

Recent advances in the machine learning-based drug-target interaction prediction

, 2019; 20(3): 194-202.

Wen Zhang*, Weiran Lin, Ding Zhang, Siman Wang, Jingwen Shi and Yanqing Niu


DOI: 10.2174/1389200219666180821094047


Review Article

A review of theranostics applications and toxicities of carbon nanomaterials

, 2019; 20(6): 506-532.

Nitin Gupta, Divya Bharti Rai, Ashok Kumar Jangid and Hitesh Kulhari*


DOI: 10.2174/1389200219666180925094515


General Review Article

Advanced glycation end products (AGEs), glutathione and breast cancer: Factors, mechanism and therapeutic interventions

, 2019; 20(1): 65-71.

Anil K. Sharma, Var R. Sharma, Girish K. Gupta, Ghulam Md. Ashraf and Mohammad A. Kamal*


DOI: 10.2174/1389200219666180912104342



Most Accessed Articles

Serial Quantification of Urinary Protein Biomarkers to Predict Drug-induced Acute Kidney Injury

, 2019; 20(8): 656-664.

Yi Da, K. Akalya, Tanusya Murali, Anantharaman Vathsala, Chuen-Seng Tan, Sanmay Low, Hui-Ning Lim, Boon-Wee Teo, Titus Lau, Lizhen Ong and Horng-Ruey Chua*


DOI: 10.2174/1389200220666190711114504







Dysregulation of lncRNA and circRNA Expression in Mouse Testes after Exposure to Triptolide

, 2019; 20(8): 665-673.

Suping Xiong, Yanting Li, Yang Xiang, Na Peng, Chunmiao Shen, Yanqiu Cai, Dandan Song, Peng Zhang, Xiaolong Wang, Xuihui Zeng and Xiaoning Zhang*


DOI: 10.2174/1389200220666190729130020



Cannabinoids and Cytochrome P450 Interactions

, 2016; 17(3): 206-226.

Ondřej Zendulka, Gabriela Dovrtělová, Kristýna Nosková, Miroslav Turjap, Alexandra Šulcová, Lumír Hanuš and Jan Juřica


DOI: 10.2174/1389200217666151210142051





Editor-in-Chief

Ming Hu
University of Houston College of Pharmacy
Houston, TX
USA

Biography View Full Editorial Board

Journal History

Current Drug Metabolism was launched in 2000. Dr. Michael Sinz serves as the Editor-in-Chief of the journal.
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Scopus CiteScore Metrics: 2.75

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