ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

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  • 16th of 60 in Chemistry & Medicinal

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.249
5 - Year: 3.508

Abstracts Ahead of Print

Autologous cell therapy for vascular regeneration: the role of proangiogenic cells


Vanessa Bianconi, Francesca Fallarino, Massimo Raffaele Mannarino, Francesco Bagaglia, Meisam Naeimi Kararoudi, Caterina Oriana Aragona, Rita Romani and Matteo Pirro.


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Endothelial and circulating progenitor cells in hematological diseases and allogeneic hematopoietic stem cell transplantation


Annalisa Ruggeri, Annalisa Paviglianiti, Fernanda Volt, Chantal Kenzey, Hanadi Rafii, Vanderson Rocha and Eliane Gluckman.


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Pharmacological Targeting Of Neuronal Kv7.2/3 Channels: A Focus On Chemotypes And Receptor Sites


Francesco Miceli, Maria Virginia Soldovieri, Paolo Ambrosino, Laura Manocchio, Alessandro Medoro, Ilaria Mosca and Maurizio Taglialatela.


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The Renal Outer Medullary Potassium channel (ROMK): an intriguing pharmacological target for an innovative class of diuretic drugs


Vincenzo Calderone, Alma Martelli, Eugenia Piragine, Valentina Citi, Lara Testai and Maria Cristina Breschi.


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Pathophysiological role of mitochondrial potassium channels and their modulation by drugs.


Valentina Citi, Vincenzo Calderone, Alma Martelli, Maria Cristina Breschi and Lara Testai.


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Nanotechnology in Personalized Medicine: A Promising Tool for Alzheimer’s Disease Treatment


Laura de Matteis, Rafael Martin-Rapun and Jesus M De la Fuente.


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Biomarkers of Atrial Fibrillation in Metabolic Syndrome


Christos Georgakopoulos, Charalambos Vlachopoulos, Georgios Lazaros and Dimitris Tousoulis.


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ATP-binding cassette exporters: structure and mechanism with a focus on P-glycoprotein and MRP1


Maite Rocío Arana and Guillermo Altenberg.


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The Medicinal Chemistry of Therapeutic Peptides: Recent Developments in Synthesis and Design Optimizations


Anutthaman Parthasarathy, Sasikala K. Anandamma and Karunakaran A Kalesh.


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Development of Potential Small Molecule Therapeutics for Treatment of Ebola Virus


Adam Michael Schafer, Han Cheng, Charles Lee, Ruikun Du, Julianna Han, Jasmine Perez, Norton Peet, Balaji Manicassamy and Lijun Rong.


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Sunitinib in the treatment of thyroid cancer


Ferrari Silvia Martinaa, Centanni Marco, Virili Camilla, Miccoli Mario, Ferrari Paola, Ruffilli Ilaria, Ragusa Francesca, Antonelli Alessandro and Fallahi Poupak.


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Recent Advances in the Development of Pharmaceutical Agents for Metabolic Disorders: A Computational Perspective


Sridhara Janardhan, Varvara Dubovskaja, Alexey Lagunin, Venkateswara Rao, Narahari Sastry and Vladimir Poroikov.


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Anesthetic agents and neuronal autophagy. What we know and what we don’t.


Lili Xu , Jianjun Shen , Patrick M. McQuillan and Zhiyong Hu.


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Click Reactions in Chemistry of Triterpenes – Advances towards Development of Potential Therapeutics


Jan Pokorný , Lucie Borková and Milan Urban.


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Gut microbiota as a therapeutic target for metabolic disorders


Hirofumi Okubo , Yusuke Nakatsu, Akifumi Kushiyama , Takeshi Yamamotoya , Yasuka Matsunaga , Masa-ki Inoue, Midori Fujishiro, Hideaki Sakoda , Haruya Ohno , Masayasu Yoneda, Hiraku Ono and Tomoichiro Asano.


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Bisphenol A in reproduction: epigenetic effects


Rosanna Chianese, Jacopo Troisi, Sean Richards, Marika Scafuro , Silvia Fasano, Maurizio Guida , Riccardo Pierantoni and Rosaria Meccariello.


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Recent advances and perspectives in liposomes for cutaneous drug delivery


Amanda C. Caritá , Josimar O. Eloy , Marlus Chorilli, Robert J. Lee and Gislaine Ricci Leonardi.


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Fighting type-2 diabetes: present and future perspectives


Cai-Guo Yu , Ying Fu, Yuan Fang , Ning Zhang, Rong-Xin Sun , Dong Zhao, Ying-Mei Feng and Bao-Yu Zhang.


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Protective effects of the caffeine against neurodegenerative diseases


Ester Tellone, Antonio Galtieri, Annamaria Russo and Silvana Ficarra.


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Benzothiazole-based compounds in antibacterial drug discovery


Marina Gjorgjieva, Tihomir Tomašič, Danijel Kikelj and Lucija Peterlin Masic.


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Potential of plant-sourced phenols for inflammatory bowel disease


Hai-tao Xiao, Bo Wen, Xiang-Chun Shen and Zhao-xiang Bian.


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Biomarkers of atrial fibrillation in hypertension


Costas Tsioufis, Dimitrios Konstantinidis, Elias Nikolakopoulos, Evi Vemou, Theodoros Kalos, Georgios Georgiopoulos, Nikos Vogiatzakis, Aristos Ifantis, Konstantinos Konstantinou, V. Gennimata and Dimitris Tousoulis.


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Polyphenols in Food: Cancer Prevention and Apoptosis Induction


Ashita Sharma, Mandeep Kaur, Jatinder Kaur Katnoria and Avinash Kaur Nagpal.


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Metabolomics and heart diseases: from basic to clinical approach


Ignasi Barba, Mireia Andres and D Garcia Dorado.


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Metabolomic heterogeneity of urogenital tract cancers analyzed by complementary chromatographic techniques coupled with mass spectrometry


Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Renata Bujak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski.


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Biological therapy of hematologic malignancies: toward a chemotherapy-free era


Pavel Klener, Tomas Etrych and Pavel Klener.


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Risk-assessment of isolated isoflavones intake on human health


Antonella Smeriglio, Antonella Calderaro, Marcella Denaro, Giuseppina Laganà and Ersilia Bellocco.


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The Use of Naphthoquinones and Furano-naphthoquinones as Anti-invasive Agents


Nga Yi Tsang, Wai I Chik, Lai Pan Sze, Siu Wai Tsang and Hongjie Zhang.


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Collagenolytic enzymes and their applications in biomedicine


Anatoly Borisovich Shekhter, Anastasia V. Balakireva, Natalia V. Kuznetsova, Marina N. Vukolova, Petr F. Litvitsky and Andrey A Zamyatnin.


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Biomarkers of alcohol consumption in body fluids - possibilities and limitations of application in toxicological analysis


Mateusz K. Woźniak, Marek Wiergowski, Jacek Namieśnik and Marek Biziuk.


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PLATELET oxidative stress and its relationship with cardiovascular diseases in type 2 diabetes mellitus patients


Mohammed El Haouari.


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Recent developments in separation of low molecular weight heparin anticoagulants


Radosław Sadowski, Renata Gadzała-Kopciuch and Bogusław Buszewski.


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Virome and Inflammasomes, a Finely Tuned Balance with Important Consequences for the Host Health


Giulia Freer, Fabrizio Maggi and Mauro Pistello.


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Electrochemical MIP-Sensors for Drugs


Aysu Yarman, Sevinc Kurbanoglu, Katharina J. Jetzschmann, Sibel A. Ozkan, Ulla Wollenberger and Frieder Scheller.


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Electronic Noses in Medical Diagnostics


Wojciech Wojnowski, Anna Partyka, Tomasz Dymerski, Jacek Gębicki and Jacek Namieśnik.


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Current progress of lipid analysis in metabolic diseases by mass spectrometry methods


Adriana Mika, Tomasz Sledzinski and Piotr Stepnowski.


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Gaultheria Ethnobotany and Bioactivity: Blueberry Relatives with Anti-inflammatory, Antioxidant, and Anticancer Constituents


Bin-sheng Luo, Rong-hui Gu, Edward J. Kennelly and Chunlin Long.


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Circulating microRNAs: valuable biomarkers for diagnosis and prognosis of gastric cancer


Najibeh Shekari , Behzad Baradaran , Dariush Shanehbandi and Tohid Kazemi.


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Chemoprevention of Skin Carcinomas in High-Risk Transplant Recipients


Paola Savoia, Elisa Zavattaro and Ottavio Cremona.


View Abstract


Rutin as neuroprotective agent: from bench to bedside


Barbara Budzynska, Caterina Faggio, Marta Kruk-Slomka, Dunja Samec, Seyed Fazel Nabavi, Antoni Sureda, Kasi Pandima Devi and Seyed Mohammad Nabavi.


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Recent Research Trends on Bismuth Compounds in Cancer Chemo- and Radiotherapy


Mateusz Kowalik, Joanna Masternak and Barbara Barszcz.


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Hyphenated Mass Spectrometry Techniques in the Diagnosis of Amyloidosis


Marta Spodzieja, Sylwia Rodziewicz-Motowidło and Aneta Szymanska.


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Ag+ complexes as potential therapeutic agents in medicine and pharmacy


Aleksandra Hecel, Paulina Kolkowska, Karolina Krzywoszynska, Agnieszka Szebesczyk, Magdalena Rowinska-Zyrek and Henryk Kozlowski.


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Cysteine-rich proteins for drug delivery and diagnosis


Guang Yang, Yue Lu, Hunter N. Bomba and Zhen Gu.


View Abstract


Enzyme-Instructed Self-assembly in Biological Milieu for Theranostics Purpose


Zhentao Huang, Qingxin Yao, Simin Wei, Jiali Chen and Yuan Gao.


View Abstract


Organic Nanotheranostics for Photoacoustic Imaging-Guided Phototherapy


Houjuan Zhu , Chen Xie , Peng Chen and Kanyi Pu.


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Molecular mechanisms of epigenetic regulators as activatable targets in cancer theranostics


Yinglu Li, Zhiming Li and Wei-Guo Zhu.


View Abstract


Influenza Virus: Small Molecule Therapeutics and Mechanisms of Antiviral


Julianna Han, Jasmine Perez, Adam Schafer, Han Cheng, Norton Peet, Lijun Rong and Balaji Manicassamy.


View Abstract


Smart Organic-Inorganic Nanogels for Activatable Theranostics


Fangyuan Li, Zeyu Liang and Daishun Ling.


View Abstract


Old Drugs and New Targets as an Outlook for the Treatment of Tuberculosis


Jan Zitko and Martin Doležal.


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Circulating stem/progenitor cells as prognostic biomarkers in macro- and microvascular disease. A narrative review of prospective observational studies


Mauro Rigato and Gian Paolo Fadini.


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Biodegradable black phosphorus-based nanomaterials in biomedicine: theranostic applications


Zhen Wang, Zhiming Liu, Chengkang Su, Biwen Yang, Xixi Fei, Yi Li, Yuqing Hou, Henan Zhao, Yanxian Guo, Zhengfei Zhuang, Huiqing Zhong and Zhouyi Guo.


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Pharmacotranscriptomic biomarkers in glucocorticoid treatment of pediatric inflammatory bowel disease


Marianna Lucafò, Biljana Stankovic, Nikola Kotur, Alessia Di Silvestre, Stefano Martelossi, Alessandro Ventura, Branka Zukic, Sonya Pavlovic and Giuliana Decorti.


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Recent Applications of Silver Amalgam Electrodes for Analysis of Pharmaceuticals and Vitamins


Sylwia Smarzewska, Radovan Metelka, Bogusław Baś and Karel Vytřas.


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Modulation of ABC Transporters by Nuclear Receptors. Physiological, Pathological and Pharmacological Aspects


Juan Pablo Rigalli, Guillermo Nicolás Tocchetti and Johanna Weiss.


View Abstract


The Clinical translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes


Stefano Palazzolo, Samer Bayda, Mohamad Hadla, Isabella Caligiuri, Giuseppe Corona, Giuseppe Toffoli and Flavio Rizzolio.


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New Molecular Targets and Strategies for Antimalarial Discovery


Anna Caroline Aguiar, Lorena R. F. de Sousa, Celia R. S. Garcia, Glaucius Oliva and Rafael V C Guido.


View Abstract


Hemicellulose from Plant Biomass in Medical and Pharmaceutical Application: A Critical Review


Xinxin Liu, Qixuan Lin, Yuhuan Yan, Fenf Peng, Runcang Sun and Junli Ren.


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Hairy root cultures for the production of anti-cancer naphthoquinone compounds


Małgorzata Jeziorek, Katarzyna Sykłowska-Baranek and Agnieszka Pietrosiuk.


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Structural Design and Physicochemical Foundations of Hydrogels for Biomedical and Pharmaceutical Applications


Qingyong Li , Wen Li , Jie Xu, Zhengxiang Ning, Jiaoyan Ren and Wenzhen Liao.


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Structure-Based Approaches Targeting Parasite Cysteine Proteases


Rafael Pinto Vieira, Viviane Corrêa Santos and Rafaela Salgado Ferreira.


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Cannabis phenolics and their bioactivities


Federica Pollastro, Alberto Minassi and Luigia Grazia Fresu.


View Abstract


Inflammatory biomarkers in atrial fibrillation


Effimia Zacharia, Nikolaos Papageorgiou, Adam Ioannou, Gerasimos Siasos, Manolis Vavuranakis, George Latsios, Charalampos Vlachopoulos, Konstantinos Toutouzas, Spyridon Deftereos, Rui Providência and Dimitris Tousoulis.


View Abstract


Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines?


Resmi C Panicker, Anthony G. Coyne and Rajavel Srinivasan.


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Protozoan parasites glycosylphosphatidylinositol anchors: structures, functions and trends for drug discovery


Ana Luísa Malaco Morotti, Maristela Braga Martins-Teixeira and Ivone Carvalho.


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Potential triazole-based molecules for the treatment of neglected diseases


Susimaire Pedersoli Mantoani, Peterson de Andrade, Talita Perez Cantuaria Chierrito, Andreza Silva Figueredo and Ivone Carvalho.


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The evaluation and utilization of marine-derived bioactive compounds with anti-obesity effect


Qiu Jin , Huahua Yu and Pengcheng Li.


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Role of positron emission tomography for central nervous system involvement in systemic autoimmune diseases: status and perspectives


Daniele Mauro , Gaetano Barbagallo , Salvatore D’Angelo, Sannino Pasqualina, Saverio Naty , Caterina Bruno, Ignazio Olivieri , Rosa Daniela Grembiale and Francesco Ursini.


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Improving Metabolic Control Through Functional Foods


John G. Jones and Joao CP Silva.


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Role of infrared spectroscopy and imaging in cancer diagnosis


Saroj Kumar , Alagiri Srinivasan and Fredrik Nikolajeff.


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Phenolic compounds from edible algae: bioactivity and health benefits


Lidia Montero , Andrea del Pilar Sánchez-Camargo, Elena Ibáñez and Bienvenida Gilbert-López.


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Endocytosis of Nanoscale Systems for Cancer Treatments


Kai Chen, Xue Li, Hongyan Zhu, Qiyong Gong and Kui Luo.


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New drugs from old natural compounds: scarcely investigated sesquiterpenes as new possible therapeutic agents


Stefania Suta, Filippo Maggi, Marcello Nicoletti, Valeria Baldan and Stefano Dall`Acqua.


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