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Reviews on Recent Clinical Trials

Volume 17, 4 Issues, 2022
ISSN: 1876-1038 (Online)
ISSN: 1574-8871 (Print)
This journal supports open access

Aims & Scope

Reviews on Recent Clinical Trials publishes high quality full-length/mini reviews, original research articles, interesting case reports, drug clinical trial studies and guest edited thematic issues on recent clinical trials of major importance. The journal's aim is to publish the highest quality articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development, therapeutics, meta analysis, trial logistics, design and conduct of trials, statistical methods, synthesis and evidence evaluation, decision analysis, reviews, case reports and commentaries on current or controversial issues.

The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.

Reviews on Recent Clinical Trials

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Volume 17

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Number 1





Letter Article




Perspective Article

COVID-19 Vaccinations: Summary Guidance for Cancer Patients in 28 Languages: Breaking Barriers to Cancer Patient Information

, 17(1): 11 - 14

Davide Mauri*, Konstantinos Kamposioras, Lampriani Tsali, Mario Dambrosio, Berardino De Bari, Nadia Hindi, Carl Salembier, Joanna Nixon, Tzachanis Dimitrios, Flippo Alongi, Hassan Hameed, Antonios Valachis, Konstantinos Papadimitriou, Stefanie Corradini, Lazar Popovic, Jindrich Kopecky, Andres Rodriguez, Katarina Antunac, Junlin Yi, Jozsef Lovey, Primoz Strojan, Haytham Saraireh, Ranveig Røtterud, Marzanna Chojnacka, Santa Cruz Olalla, Natalia Chilingirova, Ramon Andrade De Mello, Giovanna Araujo Amaral, Farsid Arbabi, Radu Vidra, Erjeta Rapushi, Dan Takeuchi, Chirstos Christopoulos, Irina Ivanova, Igor Djan, Branka Petricevic, Francesco Cellini, Iglika Mihaylova, Natalija Dedic Plavetic, Cvetka Grašič Kuhar, Elena Takeuchi, Pantelis Kountourakis, Panagiotis Ntellas, Ioanna Gazouli, Stefania Gkoura, Salih Yuce, Özlem ER, Chait Yasmina, Gireesh Kumaran, Orges Spahiu, Aasim Yusuf, Paulina Gono, Kathi Apostolidis and Maria Tolia


DOI: 10.2174/1574887116666211028145848



Review Article

Practical Review of Mechanical Ventilation in Adults and Children in the Operating Room and Emergency Department

, 17(1): 20 - 33

Christian Zanza*, Yaroslava Longhitano, Mirco Leo, Tatsiana Romenskaya, Francesco Franceschi, Andrea Piccioni, Ingrid M. Pabon, Maria T. Santarelli and Fabrizio Racca


DOI: 10.2174/1574887116666210812165615


Research Article

Correction of Androgen Deficiency in Men with Type 2 Diabetes

, 17(1): 34 - 39

Volodymyr Pankiv , Tetyana Yuzvenko, Nazarii Kobyliak* and Ivan Pankiv


DOI: 10.2174/1574887116666211202155304


Articles Ahead of Print

Viral Encephalitis in Adults: A Narrative Review


Valentina Siciliano, Rosà Tommaso, Del Vecchio Pierluigi, D'Angelillo Anna, Brigida Mattia, Longhitano Yaroslava, Zanza Christian, Santoro Michele Cosimo, Marcello Candelli, Francesco Franceschi and Andrea Piccioni*


DOI: 10.2174/1574887116666211118141117
View Abstract View on PubMed


The Gut Microbiota-Brain Axis in Acute Neurological Disease: Focus on Stroke


Saviano Angela*, Gayani Gunawardena, Zanza Christian, Longhitano Yaroslava, Migneco Alessio, Candelli Marcello, Franceschi Francesco and Ojetti Veronica


DOI: 10.2174/1574887117666220321155508
View Abstract View on PubMed


SARS-CoV-2: Impacts and Echoes


Giovanni Clemente Actis*, Rinaldo Pellicano and Davide Giuseppe Ribaldone


DOI: 10.2174/1574887117666211221170715
View on PubMed


Abstracts Ahead of Print

Is surgery worthwhile in locally-advanced NSCLC patients with persistent N2-disease after neoadjuvant therapy?


Filippo Lococo*, Marco Chiappetta, Carolina Sassorossi, Dania Nachira, Jessica Evangelista, Leonardo Petracca Ciavarella, Maria Teresa Congedo, Venanzio Porziella, Luca Boldrini, Annarita Larici, Emilio Bria and Stefano Margaritora


DOI: 10.2174/1574887117666220518102321
View Abstract


Long-term CR Multiple Myeloma Patients Show Cured or MGUS-like Minimal Residual Disease Pattern by Next Generation Flow


Alessandro Gozzetti*, Paola Pacelli, Donatella Raspadori, Elena Bestoso, Dania Tocci, Anna , Sicuranza and Monica Bocchia


DOI: 10.2174/1574887117666220516145628
View Abstract


Anorectal function with high resolution anorectal manometry in active ulcerative colitis and after remission: a pilot study.


Antonietta G Gravina*, Alessandro Federico, Angela Facchiano, Giuseppe Scidà, Raffaele Pellegrino, Giovanna Palladino, Carmelina Loguercio, Ludovico Docimo, Marco Romano and Salvatore Tolone


DOI: 10.2174/1574887117666220513110705
View Abstract


Clinical And Morphological Evaluation Of Erosive And Ulcerative Gastric Lesions In Patients With Rheumatoid Arthritis


Vladimir A. Beloglazov, Andrey V. Petrov, Vitalii B. Kaliberdenko, Kseniya V. Abramova and Shanmugaraj Kulanthaivel*


DOI: 10.2174/1574887117666220513102512
View Abstract



Patient-Reported Outcomes Measures in Perianal Fistulizing Crohn’s Disease


Natália Sousa Freitas Queiroz*, Karoline Soares Garcia, Eron Fabio Miranda and Paulo Gustavo Kotze


DOI: 10.2174/1574887117666220425125424
View Abstract


The Lesson of the First Italian Lockdown: which Impacts on Anxiety and Depressive Symptoms and Sleep Quality in Patients with Remission Inflammatory Bowel Disease


Annamaria Spina, Chiara Mazzarella, Marcello Dallio, Mario Romeo, Raffaele Pellegrino, Tommaso Durante, Marco Romano, Carmelina Loguercio, Maurizio Di Mauro, Alessandro Federico and Antonietta Gerarda Gravina*


DOI: 10.2174/1574887117666220328125720
View Abstract


Changes in Metabolic Parameters in Patients with Diabetic Kidney Disease Depending on the Status of D3


Yulia Pastukhova, Francesco Luzza, Sviatoslav Shevel, Oleksii Savchuk, Liudmyla Ostapchenko, Tetyana Falalyeyeva, Nataliia Molochek, Olena Kuryk, Oleksandr Korotkyi* and Nazarii Kobyliak


DOI: 10.2174/1574887117666220321152855
View Abstract


Radiotherapy and breast reconstruction: What is the ideal timing? A narrative review.


Evanthia Letsiou, Sergios Tsakatikas, George Vakis, Konstantinos Tsapakidis, Nikolaos Charalampakis, Alexandros Diamantis, Antigoni Poultsidi, Dimosthenis Michelakis, Eelco de Bree, Davide Mauri, Nikolaos Tsoukalas, Chrysostomos Antoniades and Maria Tolia*


DOI: 10.2174/1574887117666220314161609
View Abstract



Published Contents

Editor's Choice

Intravenous Magnesium – Lidocaine - Ketorolac Cocktail for Postoperative Opioid Resistant Pain: A Case Series of Novel Rescue Therapy

, 2021; 16(3): 288 - 293

Christian Zanza*, Yaroslava Longhitano, Edwin Lin, Jerry Luo, Marco Artico, Benedetta Savarese, Valeria Bonato, Andrea Piccioni, Francesco Franceschi, Samanta Taurone, Ludovico Abenavoli and Jack Marshall Berger


DOI: 10.2174/1574887115666201202105620



New Strategies for Clinical Trials in Autism Spectrum Disorder

, 2021; 16(2): 131 - 137

Rini Pauly, Catherine A. Ziats, Ludovico Abenavoli, Charles E. Schwartz and Luigi Boccuto*


DOI: 10.2174/1574887115666201120093634



The Management of Hemorrhoidal Disease by Dearterialization and Mucopexy

, 2021; 16(1): 60 - 66

Veronica De Simone, Francesco Litta*, Angelo Parello, Paola Campennì, Raffaele Orefice, Angelo Alessandro Marra, Marta Goglia and Carlo Ratto


DOI: 10.2174/1574887115666200506091306




Indications for Non-Invasive Ventilation in Respiratory Failure

, 2020; 15(4): 251 - 257

Simone Maria Navarra, Maria Teresa Congedo and Mariano Alberto Pennisi*


DOI: 10.2174/1574887115666200603151838




Serum Levels of Granulocyte-Macrophage-colony-stimulating Factor and Stem-cell Factor During Liver Regeneration after Partial Hepatectomy in Humans

, 2020; 15(2): 131 - 136

Diego Fiume , Ilaria Lenci, Martina Milana, Tommaso M. Manzia, Renato Massoud, Laura Tariciotti, Carmelo Russo, Luca Toti and Leonardo Baiocchi*


DOI: 10.2174/1574887115666200123113623



An Industry Perspective on Risks and Mitigation Strategies Associated with Post Conduct Phase of Clinical Trial

, 2020; 15(1): 28 - 33

Seema Bhagat*, Vaibhavi K. Kapatkar, Ashish Mane, Colette Pinto, Devang Parikh, Gaurav Mittal and Rishi Jain


DOI: 10.2174/1574887114666191016103332



Domino Liver Transplantation: Where are we Now?

, 2019; 14(3): 183 - 188

Francesco Santopaolo, Ilaria Lenci, Alessandra Bosa, Mario Angelico, Martina Milana and Leonardo Baiocchi*


DOI: 10.2174/1574887114666190320123824




Open Access Articles

COVID-19 Vaccinations: Summary Guidance for Cancer Patients in 28 Languages: Breaking Barriers to Cancer Patient Information

, 2022; 17(1): 11 - 14

Davide Mauri*, Konstantinos Kamposioras, Lampriani Tsali, Mario Dambrosio, Berardino De Bari, Nadia Hindi, Carl Salembier, Joanna Nixon, Tzachanis Dimitrios, Flippo Alongi, Hassan Hameed, Antonios Valachis, Konstantinos Papadimitriou, Stefanie Corradini, Lazar Popovic, Jindrich Kopecky, Andres Rodriguez, Katarina Antunac, Junlin Yi, Jozsef Lovey, Primoz Strojan, Haytham Saraireh, Ranveig Røtterud, Marzanna Chojnacka, Santa Cruz Olalla, Natalia Chilingirova, Ramon Andrade De Mello, Giovanna Araujo Amaral, Farsid Arbabi, Radu Vidra, Erjeta Rapushi, Dan Takeuchi, Chirstos Christopoulos, Irina Ivanova, Igor Djan, Branka Petricevic, Francesco Cellini, Iglika Mihaylova, Natalija Dedic Plavetic, Cvetka Grašič Kuhar, Elena Takeuchi, Pantelis Kountourakis, Panagiotis Ntellas, Ioanna Gazouli, Stefania Gkoura, Salih Yuce, Özlem ER, Chait Yasmina, Gireesh Kumaran, Orges Spahiu, Aasim Yusuf, Paulina Gono, Kathi Apostolidis and Maria Tolia





Thrombosed External Haemorrhoids: A Clinician’s Dilemma

, 2019; 14(4): 232 - 234

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo





Cardiovascular Risk Markers and Major Adverse Cardiovascular Events in Psoriatic Arthritis Patients

, 2018; 13(3): 199 - 209

Rosario Peluso*, Francesco Caso, Marco Tasso, Pasquale Ambrosino, Matteo Nicola Dario Di Minno, Roberta Lupoli, Livio Criscuolo, Paolo Caso, Francesco Ursini, Antonio Del Puente, Raffaele Scarpa and Luisa Costa on behalf of CaRRDs study group




Point-of-Care Lung Ultrasound in Critically ill Patients

, 2018; 13(1): 15 - 26

Gentle S. Shrestha*, Dameera Weeratunga and Kylie Baker





Treating Older HIV-1-infected Subjects With Cobicistat-boosted Darunavir in a 48-week Phase 3 Trial

, 2017; 12(3): 174 - 181

Kimberley Brown*, Brooke Patterson-Browning, Chris Liu, Meera Patel, Lisa Stewart and Richard E. Nettles




Neoadjuvant Therapy for HER2-positive Breast Cancer

, 2017; 12(2): 81 - 92

Rachel Wuerstlein* and Nadia Harbeck




Managing Expectations in the Transition to Proof of Concept Studies

, 2017; 12(2): 111 - 123

Thomas Kieber-Emmons*, Issam Makhoul, Angela Pennisi, Eric R. Siegel, Peter D. Emanuel, Bejotaloh Monzavi-Karbassi, Zenon Steplewski, J. Thaddeus Beck and Laura F. Hutchins




Potential Risks and Mitigation Strategies Before the Conduct of a Clinical Trial: An Industry Perspective

, 2016; 11(1): 47 - 55

Seema Bhagat, Vaibhavi K. Kapatkar, Meenakshi Mourya, Sucheta Roy, Shailendra Jha, Rajasekhar Reddy, Ganesh Kadhe, Amey Mane and Sandesh Sawant





Most Cited Articles


Review Article

Real-world efficacy and safety of pangenotypic direct-acting antivirals against hepatitis C virus infection

, 2019; 14(3): 173-182.

Riccardo Scotto, Antonio Riccardo Buonomo*, Nicola Schiano Moriello, Alberto Enrico Maraolo, Emanuela Zappulo, Biagio Pinchera, Ivan Gentile and Guglielmo Borgia


DOI: 10.2174/1574887114666190306154650


Editorial

Epidemiology of coronavirus disease outbreak: The Italian trends

, 2020; 15(2): 87-92.

Ludovico Abenavoli*, Pietro Cinaglia, Francesco Luzza, Ivan Gentile and Luigi Boccuto


DOI: 10.2174/1574887115999200407143449


Systemic Review Article

High flow through nasal cannula in stable and exacerbated chronic obstructive pulmonary disease patients

, 2019; 14(4): 247-260.

Andrea Bruni, Eugenio Garofalo, Gianmaria Cammarota, Paolo Murabito, Marinella Astuto, Paolo Navalesi, Francesco Luzza, Ludovico Abenavoli and Federico Longhini*


DOI: 10.2174/1574887114666190710180540


Review Article

A concise history of thiopurines for inflammatory bowel disease: From anecdotal reporting to treat-to-target algorithms

, 2019; 14(1): 4-9.

Giovanni Clemente Actis*, Rinaldo Pellicano and Davide Giuseppe Ribaldone


DOI: 10.2174/1574887113666180910120959


Research Article

Effect of chondroitin sulfate on blood serum cytokine profile during carrageenan-induced edema and monoiodoacetate-induced osteoarthritis in rats

, 2019; 14(1): 50-55.

Oleksandr Korotkyi*, Andrii Vovk, Oksana Blokhina, Kateryna Dvorshchenko, Tetyana Falalyeyeva, Ludovico Abenavoli and Liudmyla Ostapchenko


DOI: 10.2174/1574887113666181102111247


Review Article

The role of Biofilm in central venous catheter related bloodstream infections: Evidence-based nursing and review of the literature

, 2020; 15(1): 22-27.

Nicola Ielapi, Emanuela Nicoletti, Carmela Lorè, Giorgio Guasticchi, Tiziana Avenoso, Andrea Barbetta, Stefano de Franciscis, Michele Andreucci, Paolo Sapienza and Raffaele Serra*


DOI: 10.2174/1574887114666191018144739


Editorial

Thrombosed external haemorrhoids: A clinician’s dilemma

, 2019; 14(4): 232-234.

Giuseppe Sammarco, Mario Trompetto and Gaetano Gallo


DOI: 10.2174/1574887114666190927163646


Review Article

Anatomy, physiology and pathophysiology of haemorrhoids

, 2021; 16(1): 75-80.

Francesco Pata*, Alessandro Sgró, Francesco Ferrara, Vincenzo Vigorita, Gaetano Gallo and Gianluca Pellino


DOI: 10.2174/1574887115666200406115150


Systemic Review Article

Effect of kangaroo mother care on successful breastfeeding: A systematic review and meta-analysis of randomised controlled trials

, 2019; 14(1): 31-40.

Morteza Ghojazadeh, Sakineh Hajebrahimi, Fatemeh Pournaghi-Azar, Mohammad Mohseni, Naser Derakhshani and Saber Azami-Aghdash*


DOI: 10.2174/1574887113666180924165844


Review Article

Tocilizumab in sars-cov-2 patients with the syndrome of cytokine storm: A narrative review

, 2021; 16(2): 138-145.

Shanmugaraj Kulanthaivel*, Vitalii B. Kaliberdenko, Keerthanaa Balasundaram, Michael V. Shterenshis, Emidio Scarpellini and Ludovico Abenavoli


DOI: 10.2174/1574887115666200917110954


Clinical Trial

Intravenous tranexamic acid for subdural and epidural intracranial hemorrhage: Randomized, double‐blind, placebo-controlled trial

, 2019; 14(4): 286-291.

Pouya Ebrahimi, Javad Mozafari*, Reza Bahrami Ilkhchi, Mohammad Ghasem Hanafi and Maryam Mousavinejad


DOI: 10.2174/1574887114666190620112829


Review Article

Stapled surgery for hemorrhoidal prolapse: From the beginning to modern times

, 2021; 16(1): 39-53.

Alessandro Sturiale*, Bernardina Fabiani, Claudia Menconi, Danilo Cafaro, Felipe Celedon Porzio and Gabriele Naldini


DOI: 10.2174/1574887115666200310164519


Review Article

Gut alterations in septic patients: A biochemical literature review

, 2020; 15(4): 289-297.

Yaroslava Longhitano*, Christian Zanza, Duraiyah Thangathurai, Samanta Taurone, Daniela Kozel, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200811105251


Review Article

Bedside cardiac pocus in emergency setting: A practice review

, 2020; 15(4): 269-277.

Christian Zanza*, Yaroslava Longhitano, Marco Artico, Gianmaria Cammarota, Andrea Barbanera, Fabrizio Racca, Andrea Audo, Enrico Ravera, Alessio Migneco, Andrea Piccioni and Francesco Franceschi


DOI: 10.2174/1574887115666200802023306



Most Accessed Articles


Epidemiology of Coronavirus Disease Outbreak: The Italian Trends

, 2020; 15(2): 87-92.

Abenavoli, Ludovico; Cinaglia, Pietro; Luzza, Francesco; Gentile, Ivan; Boccuto, Luigi


DOI: 10.2174/1574887115999200407143449


Anatomy, Physiology and Pathophysiology of Haemorrhoids

, 2021; 16(1): 75-80.

Pata, Francesco; Sgrò, Alessandro; Ferrara, Francesco; Vigorita, Vincenzo; Gallo, Gaetano; Pellino, Gianluca


DOI: 10.2174/1574887115666200406115150


Barriers and Facilitators in Conducting Clinical Trials in Inflammatory Bowel Disease: A Monocentric Italian Survey

, 2020; 15(2): 137-144.

Larussa, Tiziana; Suraci, Evelina; Marasco, Raffaella; Imeneo, Maria; Dumitrascu, Dan L.; Abenavoli, Ludovico; Luzza, Francesco


DOI: 10.2174/1574887115666200224113520


The Role of Biofilm in Central Venous Catheter Related Bloodstream Infections: Evidence-Based Nursing and Review of the Literature

, 2020; 15(1): 22-27.

Ielapi, Nicola; Nicoletti, Emanuela; Lorè, Carmela; Guasticchi, Giorgio; Avenoso, Tiziana; Barbetta, Andrea; de Franciscis, Stefano; Andreucci, Michele; Sapienza, Paolo; Serra, Raffaele


DOI: 10.2174/1574887114666191018144739



Stapled Surgery for Hemorrhoidal Prolapse: From the Beginning to Modern Times

, 2021; 16(1): 39-53.

Sturiale, Alessandro; Fabiani, Bernardina; Menconi, Claudia; Cafaro, Danilo; Porzio, Felipe Celedon; Naldini, Gabriele


DOI: 10.2174/1574887115666200310164519


Tocilizumab in SARS-CoV-2 Patients with the Syndrome of Cytokine Storm: A Narrative Review

, 2021; 16(2): 138-145.

Kulanthaivel, Shanmugaraj; Kaliberdenko, Vitalii B.; Balasundaram, Keerthanaa; Shterenshis, Michael V.; Scarpellini, Emidio; Abenavoli, Ludovico


DOI: 10.2174/1574887115666200917110954


Do We Have Another Option to Treat Bleeding Hemorrhoids? The Emborrhoid Technique: Experience in 16 Patients

, 2021; 16(1): 81-86.

Moggia, Elisabetta; Talamo, Giuseppina; Gallo, Gaetano; Bianco, Angelo; Barattini, Matteo; Salsano, Giancarlo; Zefiro, Daniele; Stefanini, Teseo; Berti, Stefano


DOI: 10.2174/1574887115666200313102246


Classifications and Clinical Assessment of Haemorrhoids: The Proctologist’s Corner

, 2021; 16(1): 10-16.

Picciariello, Arcangelo; Tsarkov, Petr V.; Papagni, Vincenzo; Efetov, Sergey; Markaryan, Daniel R.; Tulina, Inna; Altomare, Donato F.


DOI: 10.2174/1574887115666200312163940


Gut Alterations in Septic Patients: A Biochemical Literature Review.

, 2020; 15(4): 289-297.

Longhitano, Yaroslava; Zanza, Christian; Thangathurai, Duraiyah; Taurone, Samanta; Kozel, Daniela; Racca, Fabrizio; Audo, Andrea; Ravera, Enrico; Migneco, Alessio; Piccioni, Andrea; Franceschi, Francesco


DOI: 10.2174/1574887115666200811105251


Impact of Covid-19 on Mental Health: An Overview

, 2021; 16(3): 227-231.

Kshirsagar, Minal M.; Dodamani, Arun S.; Dodamani, Girija A.; Khobragade, Vrushali R.; Deokar, Rahul N.


DOI: 10.2174/1574887115666210105122324


Bedside Cardiac Pocus in Emergency Setting: A Practice Review.

, 2020; 15(4): 269-277.

Zanza, Christian; Longhitano, Yaroslava; Artico, Marco; Cammarota, Gianmaria; Barbanera, Andrea; Racca, Fabrizio; Audo, Andrea; Ravera, Enrico; Migneco, Alessio; Piccioni, Andrea; Franceschi, Francesco


DOI: 10.2174/1574887115666200802023306


Metabolic Benefits of Probiotic Combination with Absorbent Smectite in type 2 Diabetes Patients a Randomised Controlled Trial

, 2021; 16(1): 109-119.

Kobyliak, Nazarii; Abenavoli, Ludovico; Falalyeyeva, Tetyana; Kovalchuk, Oleksandr; Kyriienko, Dmytro; Komisarenko, Iuliia


DOI: 10.2174/1574887115666200709141131


Youtube as a Source of Patients’ and Specialists’ Information on Hemorrhoids and Hemorrhoid Surgery

, 2020; 15(3): 219-226.

Sturiale, Alessandro; Dowais, Raad; Porzio, Felipe Celedon; Brusciano, Luigi; Gallo, Gaetano; Morganti, Riccardo; Naldini, Gabriele


DOI: 10.2174/1574887115666200525001619




Editor-in-Chief

graphic
Ludovico Abenavoli
Department of Health Sciences
University Magna Graecia
Catanzaro
(Italy)
Biography
View Full Editorial Board

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Journal History

Reviews on Recent Clinical Trials Journal was launched in 2006. Dr. Ludovico Abenavoli serves as the Editor-in-Chief of the journal.

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