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Mini-Reviews in Medicinal Chemistry

Volume 21, 20 Issues, 2021
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

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Volume 21

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Number 7



Biography   Open Access







Review Article (Mini-Review)

Novel Mitochondria-targeted Drugs for Cancer Therapy

, 21(7): 816 - 832

Jindriska Leischner Fialova, Martina Raudenska, Milan Jakubek, Zdenek Kejik, Pavel Martasek, Petr Babula, Adam Matkowski, Petr Filipensky and Michal Masarik*


DOI: 10.2174/1389557520666201118153242








Review Article

Current and Advanced Nanomaterials in Dentistry as Regeneration Agents: An Update

, 21(7): 899 - 918

Mohsen Yazdanian, Aghil Rahmani, Elahe Tahmasebi*, Hamid Tebyanian*, Alireza Yazdanian and Seyed Ali Mosaddad


DOI: 10.2174/1389557520666201124143449


Mini-Reviews in Medicinal Chemistry, Volume 21 (2021) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 21 (2021) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 21 (2021) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Adhatoda vasica (Nees.): A Review on its Botany, Traditional uses, Phytochemistry, Pharmacological Activities and Toxicity


Tahmida Shamsuddin, Muhammad Shaiful Alam, Md. Junaid, Rasheda Akter, S. M. Zahid Hosen, Sakia Ferdousy and Nusrat Jahan Mouri*


DOI: 10.2174/1389557521666210226152238
View Abstract View on PubMed





Update on Acrylic Resins used in Dentistry


Zbigniew Raszewski , Agnieszka Nowakowska-Toporowska*, Danuta Nowakowska and Włodzimierz Więckiewicz


DOI: 10.2174/1389557521666210226151214
View Abstract View on PubMed


Origins, Structures, and Bioactivities of Secondary Metabolites from Marine- derived Penicillium Fungi


Xiliang Yang*, Jinping Liu, Jiahui Mei , Rui Jiang, Shizheng Tu, Huafeng Deng, Jing Liu, Sumei Yang and Juan Li*


DOI: 10.2174/1389557521666210217093517
View Abstract View on PubMed




Withdrawal Notice: Pharmacological analysis of Cannabis sativa L.: A potent herbal plant


Muhammad Husnain, Muhammad Imran*, Muhammad Ibrahim, Mohammad Ali Assiri, Naveed Zubair Wattoo and Ahmad Irfan


DOI: 10.2174/1389557520666200628031644
View Abstract



Abstracts Ahead of Print


Therapeutic potential of resveratrol in the treatment of glioma: Insights into its regulatory mechanisms


Ehsan Dadgostar, Maryam Fallah, Fatemeh Izadfar, Reza Heidari-Soureshjani, Michael Aschner, Omid Reza Tamtaji* and Hamed Mirzaei*


DOI: 10.2174/1389557521666210406164758
View Abstract


Anti-aging natural compounds and their role in the regulation of metabolic pathways leading to longevity


Aqsa Muzammil, Muhammad Waqas, Ahitsham Umar, Muhammad Sufyan, Abdur Rehman, Ali Haider, Haseeb Akram, Seemab Amjad Fateh Khan, Muhammad Afzal, Muhammad Wajid, Rana Adnan Tahir and Sheikh Arslan Sehgal*


DOI: 10.2174/1389557521666210405162006
View Abstract




Anticancer potential of coumarin and its derivatives


Narayan Bhattarai, Anupa A. Kumbhar, Yuba Raj Pokharel and Paras Nath Yadav*


DOI: 10.2174/1389557521666210405160323
View Abstract


The Role of Coffee and its Bioactive Components in Platelet Function and Aging


Diego Arauna, Simón Navarrete, Matías Devia , Lyanne Rodríguez, Lemuel Reyes, Sergio Wehinger , Andrea Silva-Weiss, Iván Palomo* and Eduardo Fuentes *


DOI: 10.2174/1389557521666210405155859
View Abstract


Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections.


Namita Sharma, Anil Kumar Chhillar*, Sweety Dahiya, Aruna Punia, Pooja Choudhary, Prity Gulia, Akanksha Behl and Mehak Dangi


DOI: 10.2174/1389557521666210402150325
View Abstract


Effectiveness of Azithromycin as add-on Therapy in COVID-19 Management


Shadma Wahab*, Md Faruque Ahmad, Arshad Hussain, Shazia Usmani, Ambreen Shoaib and Wasim Ahmad


DOI: 10.2174/1389557521666210401093948
View Abstract



Published Contents

Editor's Choice

Novel Mitochondria-targeted Drugs for Cancer Therapy

, 2021; 21(7): 816 - 832

Jindriska Leischner Fialova, Martina Raudenska, Milan Jakubek, Zdenek Kejik, Pavel Martasek, Petr Babula, Adam Matkowski, Petr Filipensky and Michal Masarik*


DOI: 10.2174/1389557520666201118153242



Nanomaterials for Deep Tumor Treatment

, 2021; 21(6): 677 - 688

Daria Yu. Kirsanova*, Zaira M. Gadzhimagomedova, Aleksey Yu. Maksimov and Alexander V. Soldatov


DOI: 10.2174/1389557520666201111161705








Development and Challenges of the Discovery of HER2 Inhibitors

, 2020; 20(20): 2123 - 2134

Zhi-Gang Sun*, Liang-Hui Zhao, Zhi-Na Li and Hai-Liang Zhu*


DOI: 10.2174/1389557520666200729162118



From Antibacterial to Antitumour Agents: A Brief Review on The Chemical and Medicinal Aspects of Sulfonamides

, 2020; 20(19): 2052 - 2066

Helloana Azevedo-Barbosa, Danielle Ferreira Dias, Lucas Lopardi Franco, Jamie Anthony Hawkes and Diogo Teixeira Carvalho*


DOI: 10.2174/1389557520666200905125738



Possible Targets and Therapies of SARS-CoV-2 Infection

, 2020; 20(18): 1900 - 1907

Kasturi Sarkar, Parames C. Sil, Seyed Fazel Nabavi, Ioana Berindan-Neagoe, Cosmin Andrei Cismaru, Seyed Mohammad Nabavi and Solomon Habtemariam*


DOI: 10.2174/1389557520666200807131855



Open Access Articles

Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng






G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek





Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic







Most Cited Articles


Review Article

Synthesis and biological activity of hydrazones and derivatives: A review

, 2020; 20(5): 342-368.

Juliana de Oliveira Carneiro Brum*, Tanos Celmar Costa França, Steven R. LaPlante and José Daniel Figueroa Villar


DOI: 10.2174/1389557519666191014142448


Review Article

Parkinson’s disease: A review from pathophysiology to treatment

, 2020; 20(9): 754-767.

Bianca L.B. Marino, Lucilene R. de Souza, Kessia P.A. Sousa, Jaderson V. Ferreira, Elias C. Padilha, Carlos H.T.P. da Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1389557519666191104110908


Review Article

Benzimidazole: A milestone in the field of medicinal chemistry

, 2020; 20(7): 532-565.

Mahesh S. Vasava, Manoj N. Bhoi, Sanjay K. Rathwa, Divya J. Jethava, Prachi T. Acharya, Dhaval B. Patel and Hitesh D. Patel*


DOI: 10.2174/1389557519666191122125453



Research Article

Design, synthesis, sar study, antimicrobial and anticancer evaluation of novel 2-mercaptobenzimidazole azomethine derivatives

, 2020; 20(15): 1559-1571.

Sumit Tahlan, Balasubramanian Narasimhan*, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani and Syed Adnan Ali Shah


DOI: 10.2174/1389557518666180903151849


Review Article

The roles of flavonols/flavonoids in neurodegeneration and neuroin-flammation

, 2020; 20(15): 1475-1488.

Zehra Calis, Rasim Mogulkoc* and Abdülkerim Kasim Baltaci


DOI: 10.2174/1389557519666190617150051




Review Article

A review on anticancer potentials of benzothiazole derivatives

, 2020; 20(1): 12-23.

Nandini Pathak, Ekta Rathi, Nitesh Kumar*, Suvarna G. Kini and C. Mallikarjuna Rao


DOI: 10.2174/1389557519666190617153213


Review Article

Pharmacological and therapeutic aspects of plants from the genus ferula: A comprehensive review

, 2020; 20(13): 1233-1257.

Mohammad Sabzehzari, Mohammad Reza Naghavi, Motahare Bozari, Hossein M. Orafai, Thomas P. Johnston and Amirhossein Sahebkar*


DOI: 10.2174/1389557520666200505125618



Research Article

Assembly of benzothiazine and triazole in a single molecular entity: Synthesis of -oxicam derived novel molecules as potential antibacterial/ anti-cancer agents

, 2020; 20(10): 929-940.

Papigani Neeraja, Suryapeta Srinivas, Venkanna Banothu, B. Sridhar, Khagga Mukkanti, Pramod Kumar Dubey and Sarbani Pal*


DOI: 10.2174/1389557520666200124091315


Research Article

Synthesis of azoloquinazolines and substituted benzothiazepine as antimicrobial agents

, 2020; 20(5): 418-429.

Asmaa F. Kassem, Fatimah Alshehrei, Eman M.H. Abbas and Thoraya A. Farghaly*


DOI: 10.2174/1389557519666190603091101


Review Article

Synthesis and biological activity of embelin and its derivatives: An overview

, 2020; 20(5): 396-407.

Zhaojun Sheng*, Siyuan Ge, Min Gao, Rongchao Jian, Xiaole Chen, Xuetao Xu, Dongli Li, Kun Zhang and Wen-Hua Chen*


DOI: 10.2174/1389557519666191015202723



Most Accessed Articles



Parkinson’s Disease: A Review from Pathophysiology to Treatment

, 2020; 20(9): 754-767.

Bianca L.B. Marino, Lucilene R. de Souza, Kessia P.A. Sousa, Jaderson V. Ferreira, Elias C. Padilha, Carlos H.T.P. da Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1389557519666191104110908



From Antibacterial to Antitumour Agents: A Brief Review on The Chemical and Medicinal Aspects of Sulfonamides

, 2020; 20(19): 2052-2066.

Helloana Azevedo-Barbosa, Danielle Ferreira Dias, Lucas Lopardi Franco, Jamie Anthony Hawkes and Diogo Teixeira Carvalho*


DOI: 10.2174/1389557520666200905125738



Recent Update on the Anti-infective Potential of β-carboline Analogs

, 2021; 21(4): 398-425.

Faheem, Banoth Karan Kumar, Kondapalli Venkata Gowri Chandra Sekhar, Selvaraj Kunjiappan, Joazaizulfazli Jamalis, Rafael Balaña-Fouce and Murugesan Sankaranarayanan*


DOI: 10.2174/1389557520666201001130114


Fanconi Anemia DNA Repair Pathway as a New Mechanism to Exploit Cancer Drug Resistance

, 2020; 20(9): 779-787.

Kajal Ghosal*, Christian Agatemor, Richard I. Han, Amy T. Ku, Sabu Thomas and Sudit Mukherjee


DOI: 10.2174/1389557520666200103114556


Possible Targets and Therapies of SARS-CoV-2 Infection

, 2020; 20(18): 1900-1907.

Kasturi Sarkar, Parames C. Sil, Seyed Fazel Nabavi, Ioana Berindan-Neagoe, Cosmin Andrei Cismaru, Seyed Mohammad Nabavi and Solomon Habtemariam*


DOI: 10.2174/1389557520666200807131855


Future and Perspectives of the Zika Virus: Drug Repurposing as a Powerful Tool for Treatment Insights

, 2020; 20(18): 1917-1928.

Denise Rampini, Diego Campos Prieto, Ana Luisa Colzi, Renan Vinícius de Araújo and Jeanine Giarolla*


DOI: 10.2174/1389557520666200711174007


Psoralen: A Biologically Important Coumarin with Emerging Applications

, 2020; 20(18): 1838-1845.

Abhinay Thakur, Rohit Sharma, Vivek Sheel Jaswal, Eugenie Nepovimova, Ashun Chaudhary* and Kamil Kuca*


DOI: 10.2174/1389557520666200429101053



Regulation of Catechins in Uric Acid Metabolism Disorder Related Human Diseases

, 2020; 20(18): 1857-1866.

Dan Wu, Wenji Zhang, Xingfei Lai, Qiuhua Li, Lingli Sun, Ruohong Chen, Shili Sun* and Fanrong Cao*


DOI: 10.2174/1389557520666200719015919


Monocyclic β -Lactam: A Review on Synthesis and Potential Biological Activities of a Multitarget Core

, 2020; 20(16): 1653-1682.

Taíse H.O. Leite, Mauricio F. Saraiva*, Alessandra C. Pinheiro and Marcus Vinícius N. de Souza


DOI: 10.2174/1389557520666200619114820





Co-Editors

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
graphic
Muhammad Iqbal Choudhary
(27325 citations)
H.E.J. Research Institute of Chemistry
University of Karachi
Karachi
(Pakistan)
Biography
graphic
Davide Barreca
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences
University of Messina
Messina
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Mini-Reviews in Medicinal Chemistry was launched in 2001. Dr. Atta-ur-Rahman, Dr. M. Iqbal Choudhary and Dr. Davide Barreca are the Co-Editors of the journal.

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