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"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issues

Opportunities and challenges in anticandidal drug discovery and development

Guest Editor(s): Mohammad Abid
Tentative Publication Date: September, 2018
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Published Special Issues


Letters in Drug Design & Discovery, Volume 15, Number 03
Guest Editor(s): Gokhan Zengin, Marcello Locatelli

Authors' Comments
I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide. I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!

Dima Sabbah
(Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan)

Letters in Drug Design & Discovery


Volume 15


Number 9

Biography   Open Access

Research Article

Research Article

Research Article

Design, Synthesis and anti-HIV-1 Activity of Modified Styrylquinolines

, 15(9): 937 - 944

Shivani Mahajan, Shiv Gupta, Nisha Jariwala, Deepali Bhadane , Late K.K. Bhutani, Smita Kulkarni* and Inder Pal Singh*

DOI: 10.2174/1570180815666171212143339

Research Article

Research Article

Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

, 15(9): 951 - 956

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep , David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*

DOI: 10.2174/1570180815666180102141640

Research Article

Research Article

Coumarinyl Aryl/Alkyl Sulfonates with Dual Potential: Alkaline Phosphatase and ROS Inhibitory Activities; In Silico Molecular Modeling and ADME Evaluation

Uzma Salar, Khalid Mohammed Khan*, Syeda Abida Ejaz, Abdul Hameed, Mariya Al-Rashida, Shahnaz Perveen, Muhammad Nawaz Tahir, Jamshed Iqbal and Muhammad Taha

View Abstract

The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy

Paula Sofia Coutinho Medeiros, Ana Lucia Marques Batista de Carvalho*, Cristina Ruano, Juan Carlos Otero and Maria Paula Matos Marques

View Abstract

Design and Synthesis of Benzopyranopyrimidinyl Phosphonates as Cytotoxic and Antioxidant Agents

Sarva Santhisudha, Tenkayala Sobha Rani, Peddaiahgari Vasu Govardhana Reddy and Cirandur Suresh Reddy

View Abstract

Dual Acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents

Srinubabu Maddela, Githa Elizabeth Mathew, Della Grace Thomas Parambi, Fakhrya Aljoufi and Bijo Mathew*

View Abstract

QSAR and Docking Studies of DATA Analogues as HIV-1 Reverse Transcriptase Inhibitors

Jianbo Tong*, Shan Lei, Pei Shan, Shangshang Qin and Yang Wang

View Abstract

Synthesis, Antimicrobial Evaluation and in silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives

Mir Mohammad Masood, Mohammad Irfan, Shadab Alam , Phool Hasan, Aarfa Queen, Shifa Shahid, Muhammad Zahid, Amir Azam and Mohammad Abid*

View Abstract

Synthesis and Antichlamydial Activity of Novel Phenazines

Xiaofeng Bao, Xiaowei Yu, Chao Xia, Ningjing Yang, Shengju Yang and Yu Zhao*

View Abstract

Oxime K033 – Reactivation activity of cholinesterases inhibited by various nerve agents and organophosphorus pesticides

Kamil Kuca*, Kamil Musilek, Daniel Jun, Jaroslav Pejchal, Ondrej Krejcar, Marek Penhaker, Qinghua Wu, Raquel O. Lopes, Teodorico C. Ramalho, Tanos C. C. Franca, Eugenie Nepovimova and Ondrej Soukup

View Abstract

Aurones as New Porcine Pancreatic α-Amylase Inhibitors

Khashayar Roshanzamir, Elaheh Kashani-Amin, Azadeh Ebrahim-Habibi and Latifeh Navidpour*

View Abstract

Theoretical coupling and stability of boronic acid adducts with catecholamines

Eugene Demianenko, Alexey Rayevsky, Marvin A Soriano-Ursua* and Jose G. Trujillo-Ferrara

View Abstract

Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study

Xing-Hai Liu*, Han Wang, Zhi-Wen Zhai, Yan-Xia Shi, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Bao-Ju Li

View Abstract

QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors

Richa Arya, Satya P. Gupta*, S. Paliwal, Seema Kesar, Achal Mishra and Y.S. Prabhakar

View Abstract

QSAR studies on thiazole derivatives as HCV NS5A inhibitors via CoMFA and CoMSIA methods

Jiayu Li, Wenyue Tian, Diaohui Gao, Yuying Li, Yiqun Chang, Jun Xu, Junxia Zheng and Pinghua Sun*

View Abstract

Synthesis of 3-Arylindazole-1-acetic acids and In Vitro Study of Potential Antibacterial Effect

Fauzia Anjum Chattha*, Samina Kousar, Mehr un Nisa and Munawar Ali Munawar

View Abstract

Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

, 2018; 15(9): 951 - 956

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep, David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*

DOI: 10.2174/1570180815666180102141640

Inhibitory Effects of 1,4-disubstituted Thiosemicarbazide Derivatives on Streptococcus mutans and Streptococcus sanguinis Mono-species Biofilms

, 2018; 15(8): 843 - 850

Malgorzata Miazga-Karska, Maciej Wos, Agnieszka A. Kaczor, Anna Pachuta-Stec, Grazyna Ginalska and Monika Pitucha*

DOI: 10.2174/1570180814666171012164241

Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

, 2018; 15(7): 787 - 795

Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*

DOI: 10.2174/1570180815666180117155818

Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti

, 2018; 15(6): 671 - 677

Mehlika Dilek Altintop*, Nurhayat Tabanca, James J. Becnel, Jeffrey R. Bloomquist, Zafer Asim Kaplancikli and Ahmet Ozdemir

DOI: 10.2174/1570180814666171002155548

Antimicrobial, Gastroprotective and Healing Effect of the Hydroalcoholic Extract of Astronium fraxinifolium

, 2018; 15(3): 325 - 334

Anita Oliveira Brito Pereira Bezerra Martins, Ana Luiza Albuquerque Siebra, Cicera Datiane de Morais Oliveira, Gerlania Oliveira Leite, Henrique Douglas Melo Coutinho, Margareth Linde Athayde, Aline Augusti Bolignon, Jacqueline Cosmo Andrade, Larissa Rolim Oliveira, Marta Regina Kerntopf, Roseli Barbosa, Francisco Rafael Alves Santana Cesario, Thales Silva Coutinho, Lucindo Jose Quintans-Junior and Irwin Rose Alencar de Menezes*

DOI: 10.2174/1570180814666170213160114

Synthesis and Antimicrobial Activity of Some Novel Substituted 3-(Thiophen-2-yl)pyrazole-based Heterocycles

, 2017; 14(11): 1316 - 1323

Bakr F. Abdel-Wahab*, Abdelbasset A. Farahat, Ghada E. A. Awad and Gamal A. El-Hiti*

DOI: 10.2174/1570180814666170327162447

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