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Endorsements

"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issues

Opportunities and challenges in anticandidal drug discovery and development


Guest Editor(s): Mohammad Abid
Tentative Publication Date: September, 2018
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Published Special Issues

NEW INSIGHTS ON CHARACTERIZATION AND BIOLOGICAL ACTIVITIES OF NATURAL PRODUCTS


Letters in Drug Design & Discovery, Volume 15, Number 03
Guest Editor(s): Gokhan Zengin, Marcello Locatelli

Authors' Comments
I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide. I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!

Dima Sabbah
(Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan)


Letters in Drug Design & Discovery

,

Volume 15

-

Number 9



Biography   Open Access





Research Article





Research Article





Research Article

Design, Synthesis and anti-HIV-1 Activity of Modified Styrylquinolines

, 15(9): 937 - 944

Shivani Mahajan, Shiv Gupta, Nisha Jariwala, Deepali Bhadane , Late K.K. Bhutani, Smita Kulkarni* and Inder Pal Singh*


DOI: 10.2174/1570180815666171212143339






Research Article





Research Article

Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

, 15(9): 951 - 956

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep , David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*


DOI: 10.2174/1570180815666180102141640






Research Article





Research Article





Coumarinyl Aryl/Alkyl Sulfonates with Dual Potential: Alkaline Phosphatase and ROS Inhibitory Activities; In Silico Molecular Modeling and ADME Evaluation


Uzma Salar, Khalid Mohammed Khan*, Syeda Abida Ejaz, Abdul Hameed, Mariya Al-Rashida, Shahnaz Perveen, Muhammad Nawaz Tahir, Jamshed Iqbal and Muhammad Taha


View Abstract


The Impact of Antioxidants from the Diet on Breast Cancer Cells Monitored by Raman Microspectroscopy


Paula Sofia Coutinho Medeiros, Ana Lucia Marques Batista de Carvalho*, Cristina Ruano, Juan Carlos Otero and Maria Paula Matos Marques


View Abstract


Design and Synthesis of Benzopyranopyrimidinyl Phosphonates as Cytotoxic and Antioxidant Agents


Sarva Santhisudha, Tenkayala Sobha Rani, Peddaiahgari Vasu Govardhana Reddy and Cirandur Suresh Reddy


View Abstract


Dual Acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents


Srinubabu Maddela, Githa Elizabeth Mathew, Della Grace Thomas Parambi, Fakhrya Aljoufi and Bijo Mathew*


View Abstract


QSAR and Docking Studies of DATA Analogues as HIV-1 Reverse Transcriptase Inhibitors


Jianbo Tong*, Shan Lei, Pei Shan, Shangshang Qin and Yang Wang


View Abstract


Synthesis, Antimicrobial Evaluation and in silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives


Mir Mohammad Masood, Mohammad Irfan, Shadab Alam , Phool Hasan, Aarfa Queen, Shifa Shahid, Muhammad Zahid, Amir Azam and Mohammad Abid*


View Abstract


Synthesis and Antichlamydial Activity of Novel Phenazines


Xiaofeng Bao, Xiaowei Yu, Chao Xia, Ningjing Yang, Shengju Yang and Yu Zhao*


View Abstract


Oxime K033 – Reactivation activity of cholinesterases inhibited by various nerve agents and organophosphorus pesticides


Kamil Kuca*, Kamil Musilek, Daniel Jun, Jaroslav Pejchal, Ondrej Krejcar, Marek Penhaker, Qinghua Wu, Raquel O. Lopes, Teodorico C. Ramalho, Tanos C. C. Franca, Eugenie Nepovimova and Ondrej Soukup


View Abstract


Aurones as New Porcine Pancreatic α-Amylase Inhibitors


Khashayar Roshanzamir, Elaheh Kashani-Amin, Azadeh Ebrahim-Habibi and Latifeh Navidpour*


View Abstract


Theoretical coupling and stability of boronic acid adducts with catecholamines


Eugene Demianenko, Alexey Rayevsky, Marvin A Soriano-Ursua* and Jose G. Trujillo-Ferrara


View Abstract


Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study


Xing-Hai Liu*, Han Wang, Zhi-Wen Zhai, Yan-Xia Shi, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Bao-Ju Li


View Abstract


QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors


Richa Arya, Satya P. Gupta*, S. Paliwal, Seema Kesar, Achal Mishra and Y.S. Prabhakar


View Abstract


QSAR studies on thiazole derivatives as HCV NS5A inhibitors via CoMFA and CoMSIA methods


Jiayu Li, Wenyue Tian, Diaohui Gao, Yuying Li, Yiqun Chang, Jun Xu, Junxia Zheng and Pinghua Sun*


View Abstract


Synthesis of 3-Arylindazole-1-acetic acids and In Vitro Study of Potential Antibacterial Effect


Fauzia Anjum Chattha*, Samina Kousar, Mehr un Nisa and Munawar Ali Munawar


View Abstract


Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

, 2018; 15(9): 951 - 956

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep, David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*


DOI: 10.2174/1570180815666180102141640



Inhibitory Effects of 1,4-disubstituted Thiosemicarbazide Derivatives on Streptococcus mutans and Streptococcus sanguinis Mono-species Biofilms

, 2018; 15(8): 843 - 850

Malgorzata Miazga-Karska, Maciej Wos, Agnieszka A. Kaczor, Anna Pachuta-Stec, Grazyna Ginalska and Monika Pitucha*


DOI: 10.2174/1570180814666171012164241



Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

, 2018; 15(7): 787 - 795

Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*


DOI: 10.2174/1570180815666180117155818



Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti

, 2018; 15(6): 671 - 677

Mehlika Dilek Altintop*, Nurhayat Tabanca, James J. Becnel, Jeffrey R. Bloomquist, Zafer Asim Kaplancikli and Ahmet Ozdemir


DOI: 10.2174/1570180814666171002155548



Antimicrobial, Gastroprotective and Healing Effect of the Hydroalcoholic Extract of Astronium fraxinifolium

, 2018; 15(3): 325 - 334

Anita Oliveira Brito Pereira Bezerra Martins, Ana Luiza Albuquerque Siebra, Cicera Datiane de Morais Oliveira, Gerlania Oliveira Leite, Henrique Douglas Melo Coutinho, Margareth Linde Athayde, Aline Augusti Bolignon, Jacqueline Cosmo Andrade, Larissa Rolim Oliveira, Marta Regina Kerntopf, Roseli Barbosa, Francisco Rafael Alves Santana Cesario, Thales Silva Coutinho, Lucindo Jose Quintans-Junior and Irwin Rose Alencar de Menezes*


DOI: 10.2174/1570180814666170213160114



Synthesis and Antimicrobial Activity of Some Novel Substituted 3-(Thiophen-2-yl)pyrazole-based Heterocycles

, 2017; 14(11): 1316 - 1323

Bakr F. Abdel-Wahab*, Abdelbasset A. Farahat, Ghada E. A. Awad and Gamal A. El-Hiti*


DOI: 10.2174/1570180814666170327162447



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