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Infectious Disorders - Drug Targets

Formerly: Current Drug Targets - Infectious Disorders

Volume 19, 4 Issues, 2019
ISSN: 2212-3989 (Online)
ISSN: 1871-5265 (Print)
This journal supports open access

Aims & Scope

Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments in medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews and research articles written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continue to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug design, discovery and development.

Infectious Disorders - Drug Targets

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Volume 19

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Number 1



Preface   Open Access



Review Article



Review Article   Open Access

Ebola Therapeutic Study and Future Directions

, 19(1): 17 - 29

Da-Yong Lu*, Hong-Ying Wu, Nagendra S. Yarla, Ting-Ren Lu*, Bin Xu and Jian-Ding


DOI: 10.2174/1871526518666180813160348




Systemic Review Article



Research Article

Prediction of the Omp16 Epitopes for the Development of an Epitope-based Vaccine Against Brucellosis

, 19(1): 36 - 45

Marzieh Rezaei, Mohammad Rabbani-khorasgani*, Sayyed Hamid Zarkesh-Esfahani, Rahman Emamzadeh and Hamid Abtahi


DOI: 10.2174/1871526518666180709121653




Research Article

An Outbreak of ESBL-producing Klebsiella pneumoniae in an Iranian Referral Hospital: Epidemiology and Molecular Typing

, 19(1): 46 - 54

Shima Mahmoudi, Babak Pourakbari, Aliakbar Rahbarimanesh, Mohammad Reza Abdosalehi, Keyghobad Ghadiri and Setareh Mamishi*


DOI: 10.2174/1871526518666180507121831




Research Article

Prediction and Analysis of Three-Dimensional Structure of the p7- Transactivated Protein1 of Hepatitis C Virus

, 19(1): 55 - 66

Mahmoud M. El Hefnawi*, Mohamed E. Hasan, Amal Mahmoud, Yehia A. Khidr, Wessam H. El Behaidy, El-sayed A. El-absawy and Alaa A. Hemeida


DOI: 10.2174/1871526518666171215123214




Research Article

There is no Difference Between Sequences of HIV-1 Infected Patients with Stable Clinical Status and HIV-1 Reference Sequence

, 19(1): 67 - 72

Marzyeh Nili, Katayoon Tayeri, Mohamad Gholami, Samaneh Moallemi, Farzaneh Sabahi, Saber Kalhori, Kazem Baesi* and Mehrdad Hasibi*


DOI: 10.2174/1871526518666180222111611




Articles Ahead of Print



PZQ Therapy: How Close are we in the Development of Effective Alternative Anti-schistosomal Drugs?


Raphael Taiwo Aruleba*, Tayo Alex Adekiya, Babatunji Emmanuel Oyinloye, Priscilla Masamba, Londiwe Simphiwe Mbatha, Ashley Pretorius and Abidemi Paul Kappo


View Abstract View on PubMed




Incidence and Risk Factors of Brucellosis in Kermanshah Province, Iran During 2010-2014


Jalil Rajabi, Ramin Hamidi-Farahani, Feizollah Mansouri and Saeed Soleiman-Meigooni*


View Abstract View on PubMed



High-Level Aminoglycoside Resistance in Enterococcus Faecalis and Enterococcus Faecium; as a Serious Threat in Hospitals


Mahmoud Khodabandeh, Mohsen Mohammadi , Mohammad Reza Abdolsalehi, Meysam Hasannejad-Bibalan , Mehrdad Gholami , Azadeh Alvandimanesh, Abazar Pournajaf and Ramazan Rajabnia*


View Abstract View on PubMed



The Prevalence of Bacteriospermia in Infertile Men and Association with Semen Quality in Southwestern Iran


Mohammad Motamedifar*, Yalda Malekzadegan, Parisa Namdari, Behzad Dehghani, Bahia Namavar Jahromi and Jamal Sarvari


View Abstract View on PubMed


Abstracts Ahead of Print



Plasmid-Mediated Quinolone Resistance in Pseudomonas aeruginosa Isolated from Burn Patients in Tehran, Iran


Azam Molapour, Amir Peymani*, Parvaneh Saffarain, Narges Habibollah-Pourzereshki and Pooya Rashvand


View Abstract



Allopurinol and loss of consciousness in a 78-old year man suffering from gout


Mahnaz Arian, Mina Akbari Rad *, Ahmad Bagheri Moghaddam, Abdollah Firoozi and Mohammad Jami


View Abstract


Post-Traumatic Endophthalmitis due to Acinetobacter radioresistens: Virulence Potential of Commensal Bacteria


Priya Datta, Menal Gupta*, Pooja Kumari , Varsha Gupta, Subina Narang and Jagdish Chander


View Abstract


Hepatitis C virus: Efficacy of new DAAs Regimens.


Amal Ahmed Mohamed, Naglaa El-Toukhy Ramadan El-Toukhy, Ebada Mohamed Said, Hoda Mohamed Rabie Gabal, Hossameldin AbdelAziz, Wahid Doss, Hadeel El-Hanafi, Hala H. El Deeb, Seham Mahmoud, Mahmoud Elkadeem, Hassan Salama Shalby and Sherief Abd-Elsalam*


View Abstract



Trichomonas Vaginalis Infection among Women Attending laboratory Centers in Ilam, Iran


Sasan Nikpay, Masoumeh Otaghi, Milad Azami, Marzieh Karimi and Jahangir Abdi*


View Abstract



Editor's Choice

Ebola Therapeutic Study and Future Directions

, 2019; 19(1): 17 - 29

Da-Yong Lu*, Hong-Ying Wu, Nagendra S. Yarla, Ting-Ren Lu*, Bin Xu and Jian-Ding


DOI: 10.2174/1871526518666180813160348



Current Updates on Role of Lipids in Hematopoiesis

, 2018; 18(3): 192 - 198

Priyanka Bansal, Priyanka Dahate, Sanjeev Raghuwanshi, Durga Shankar Sharma, Narasaiah Kovuru, Usha Gutti, Nagendra Sastry Yarla and RavI Kumar Gutti*


DOI: 10.2174/1871526518666180405155015




HAART in HIV/AIDS Treatments: Future Trends

, 2018; 18(1): 15 - 22

Da-Yong Lu*, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu, Jian Ding and Ting-Ren Lu


DOI: 10.2174/1871526517666170505122800







Evaluation of Antimicrobial and Antiviral Activities of Different Venoms

, 2016; 16(1): 44 - 53

Sadik Kalayci, Zeynep Ustaoglu Iyigundogdu, Muge M. Yazici, Burcin A. Asutay, Okan Demir and Fikrettin Sahin


DOI: 10.2174/1871526516666160108115307



Genotyping of ESBL Producing Uropathogenic and Diarrheagenic Escherichia coli in Southeast of Iran

, 2015; 15(2): 118 - 124

Hesam Alizade, Fatemeh Fallah, Reza Ghanbarpour, Mohammad R. Aflatoonian, Arezou Taherpour, Hamid Sharifi and Hossein Goudarzi


DOI: 10.2174/1871526515666150724113847



Open Access Articles

Ebola Therapeutic Study and Future Directions

, 2019; 19(1): 17 - 29

Da-Yong Lu*, Hong-Ying Wu, Nagendra S. Yarla, Ting-Ren Lu*, Bin Xu and Jian-Ding




Burden of Multidrug Resistant Mycobacterium tuberculosis Among New Cases in Al-Madinah Al-Monawarah, Saudi Arabia

, 2017; 17(1): 14 - 23

Mogahid M. Elhassan, Hassan A. Hemeg, Miskelyemen A. Elmekki, Khalid A. Turkistani and Ahmed A. Abdul-Aziz






The Seattle Structural Genomics Center for Infectious Disease (SSGCID)

, 2009; 9(5): 493 - 506

P. J. Myler, R. Stacy, L. Stewart, B. L. Staker, W. C. Van Voorhis, G. Varani and G. W. Buchko




New Approaches to Structure-Based Discovery of Dengue Protease Inhibitors

, 2009; 9(3): 327 - 343

S. M. Tomlinson, R. D. Malmstrom and S. J. Watowich






Drug Targets in Mycobacterial Sulfur Metabolism

, 2007; 7(2): 140 - 158

Devayani P. Bhave, Wilson B. Muse III and Kate S. Carroll





Most Cited Articles

Tuberculosis: Current Treatment, Diagnostics, and Newer Antitubercular Agents in Clinical Trials

, 2015; 15(1): 32-41.

Mohamed Jawed Ahsan, Mohammad Yousuf Ansari, Sabina Yasmin, Surender Singh Jadav, Pradeep Kumar, Shiv Kumar Garg, Ajay Aseri and Habibullah Khalilullah


DOI: 10.2174/1871526514666140923153329


Candidiasis: A Fungal Infection- Current Challenges and Progress in Prevention and Treatment

, 2015; 15(1): 42-52.

Umme Hani, Hosakote G. Shivakumar, Rudra Vaghela, Riyaz Ali M. Osmani and Atul Shrivastava


DOI: 10.2174/1871526515666150320162036



Lung Cancer May Increase Serum Procalcitonin Level

, 2015; 15(1): 57-63.

Virginie Avrillon, Myriam Locatelli-Sanchez, Laure Folliet, Melodie Carbonnaux, Emilie Perino, Gaelle Fossard, Marine Desseigne, Nathalie Freymond, Laurence Geriniere, Emilie Perrot, Pierre-Jean Souquet and Sebastien Couraud


DOI: 10.2174/1871526515666150320162950


Bacterial Multidrug Efflux Pumps of the Major Facilitator Superfamily as Targets for Modulation

, 2016; 16(1): 28-43.

Sanath Kumar, Guixin He, Prathusha Kakarla, Ugina Shrestha, Ranjana KC, Indrika Ranaweera, T. Mark Willmon, Sharla R. Barr, Alberto J. Hernandez and Manuel F. Varela


DOI: 10.2174/1871526516666160407113848


Bacteriocins Active Against Multi-Resistant Gram Negative Bacteria Implicated in Nosocomial Infections

, 2015; 15(1): 2-12.

Hanen Ghodhbane, Sabrine Elaidi, Jean-Marc Sabatier, Sami Achour, Jeannette Benhmida and Imed Regaya


DOI: 10.2174/1871526514666140522113337



Effect of Verbascum thapsus Ethanol Extract on Induction of Apoptosis in Trichomonas vaginalis in vitro

, 2015; 15(2): 125-130.

Zohreh F. Kashan, Mohsen Arbabi, Mahdi Delavari, Hossein Hooshyar, Mohsen Taghizadeh and Zeynab Joneydy


DOI: 10.2174/1871526515666150724114924



Efficacy of Sofosbuvir Plus Ribavirin with or Without Peginterferon- Alfa in Treatment of a Cohort of Egyptian Patients with Hepatitis C Virus Infection

, 2017; 17(2): 95-100.

Ossama A. Ahmed, Hany H. Kaisar, Nehad Hawash, Hossam Samir, Sherif S. T. Shabana, Mohamed Hassan A. Fouad, Fatma Rizk and Sherief Abd-Elsalam*


DOI: 10.2174/1871526517666170417143216



Most Accessed Articles

Effects of Micro RNAs and their Targets in Periodontal Diseases

, 2018; 18(3): 183-191.

Samane Bourbour, Maryam Beheshti, Hossein Kazemian and Abbas Bahador*


DOI: 10.2174/1871526518666180405155327


Current Updates on Role of Lipids in Hematopoiesis

, 2018; 18(3): 192-198.

Priyanka Bansal, Priyanka Dahate, Sanjeev Raghuwanshi, Durga Shankar Sharma, Narasaiah Kovuru, Usha Gutti, Nagendra Sastry Yarla and RavI Kumar Gutti*


DOI: 10.2174/1871526518666180405155015


Different Degrees of Immune Recovery Using Antiretroviral Regimens with Vonavir or Zidovudine/Lamivudine/Efavirenz in HIVPositive Patients Receiving First Line Treatment in Iran

, 2018; 18(3): 207-213.

Leila Sadeghi, Samaneh Moallemi, Reza Adl Tabatabai, Ali Esmaeilzadeh, Sara Ahsani-Nasab, Niloofar Eghbal Ahmadi, Saeed Bayanolhagh, Masoomeh Lolaie, Arsalan Narouei, SeyedAhmad SeyedAlinaghi* and Minoo Mohraz*


DOI: 10.2174/1871526518666180108104031


Ebola Virus: Current and Future Perspectives

, 2015; 15(1): 20-31.

Surender Singh Jadav, Anoop Kumar, Mohamed Jawed Ahsan and Venkatesan Jayaprakash


DOI: 10.2174/1871526515666150320162259



Community Acquired Pseudomonas Aeruginosa Pneumonia in a Young Athlete Man: A Case Report and Literature Review

, 2018; 18(3): 249-254.

Hossein Ali Rahdar, Hossein Kazemian, Lida Bimanand, Shahram Shahraki-Zahedani, Seifu Gizaw Feyisa, Elahe Taki, Seyed Asghar Havaei and Morteza Karami-Zarandi*


DOI: 10.2174/1871526518666180410122531


Biofilm Destruction on Endotracheal Tubes by Photodynamic Inactivation

, 2018; 18(3): 218-223.

Amanda C. Zangirolami, Natalia M. Inada, Vanderlei S. Bagnato and Kate C. Blanco*


DOI: 10.2174/1871526518666180523085754


HIV-1 Drug Resistance Profiles for the HIV Protease and Reverse Transcriptase Gene in Patients Receiving Combination Therapy in Tehran, Iran

, 2018; 18(3): 241-248.

Leila Sadeghi, Masoomeh Lolaie, Reza Adl Tabatabai, Saeed Bayanolhagh, Leila Taj, Niloofar Eghbal Ahmadi, Negin Abedinzadeh, Farzaneh Vakili, Ghazaleh Ahmadi and Minoo Mohraz*


DOI: 10.2174/1871526518666180416110259


Expression, Purification and Characterization of a GII.4 Norovirus Protease from Minerva Virus

, 2018; 18(3): 224-232.

Benjamin D. Kuiper, Kendall M. Muzzarelli, Bradley J. Keusch, Joshua Holcomb, Franck Amblard, Peng Liu, Shaoman Zhou, Iulia A. Kovari, Zhe Yang, Raymond F. Schinazi and Ladislau C. Kovari*


DOI: 10.2174/1871526518666180521091158


What about Urinary Tract Infections and its Antibiotic Resistance Bacteria in Ilam, Iran?

, 2018; 18(3): 214-217.

Khadijeh Esmaili, Reza Mohebi, Nourkhoda Sadeghifard, Morovat Taherikalani, Iraj Pakzad, Abbas Maleki, Hasan Valadbeigi and Sobhan Ghafourian*


DOI: 10.2174/1871526518666180622162229



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