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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 22, 14 Issues, 2022
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini-reviews and original articles based on experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbiome composition are welcome. The journal’s scope also covers neuroendocrinology, reproductive endocrinology, hormone secretion, and their effects on different organs.

Endocrine, Metabolic & Immune Disorders - Drug Targets

,

Volume 22

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Number 5



Review Article

Role of Polyphenol in Regulating Oxidative Stress, Inflammation, Fibrosis, and Apoptosis in Diabetic Nephropathy

, 22(5): 453 - 470

Syaifuzah Sapian*, Siti Balkis Budin, Izatus Shima Taib, Vanitha Mariappan, Satirah Zainalabidin and Kok Yong Chin


DOI: 10.2174/1871530321666211119144309


Review Article

Menstrual Disorders Related to Eating Disorders

, 22(5): 471 - 480

Walter Milano, Paola Ambrosio, Francesca Carizzone, Valeria De Biasio, Maria Gabriella Foia, Biancamaria Saetta, Maria Francesca Milano and Anna Capasso*


DOI: 10.2174/1871530321666210625145345


Meta-Analysis

Insulin Therapy and Outcome of Coronavirus Disease 2019 (COVID-19): A Systematic Review, Meta-Analysis, and Meta-Regression

, 22(5): 481 - 489

Timotius Ivan Hariyanto, Nata Pratama Hardjo Lugito, Theo Audi Yanto, Jeremia Immanuel Siregar and Andree Kurniawan*


DOI: 10.2174/1871530321666210709164925



Research Article

Subclinical Hypothyroidism in Patients with Diabetic Retinopathy: Role of Vascular Endothelial Growth Factor

, 22(5): 502 - 509

Amr A. El-Sehrawy*, Enas M. Elkhamisy, Amani E. Badawi, Heba A. Elshahawy, Eman Elsayed, Nehal T. Mohammed and Mervat M. El-Eshmawy


DOI: 10.2174/1871530321666210809151258




Research Article



Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 22 (2022) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 22 (2022) - Number 6


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print




Safety and Effectiveness of Compounded Galenic Cholic Acid for Bile Acid Synthesis Disorder: A Case Report


Davide Zanon, Francesca Burlo*, Gaia Scaramuzza, Natalia Maximova, Lorenza Matarazzo, Giuseppe Maggiore and Egidio Barbi


DOI: 10.2174/1871530322666220407114607
View Abstract View on PubMed





Searching for a Link between Bone Decay and Diabetes Type 2


Ciro Gargiulo Isacco, Kieu CD Nguyen, Van H Pham, Gianna Di Palma, Sergey K Aityan, Diego Tomassone*, Pietro Distratis, Rita Lazzaro, Mario G Balzanelli and Francesco Inchingolo


DOI: 10.2174/1871530322666220324150327
View Abstract View on PubMed


Vaccine Efficacy Denial: A Growing Concern Affecting Modern Science, and Impacting Public Health


Luca Signorini, Francesco Maria Ceruso, Elisabetta Aiello, Maria Josephine Zullo and Danila De Vito*


DOI: 10.2174/1871530322666220318092909
View Abstract View on PubMed



Abstracts Ahead of Print


Correlation between Vitamin B12 Deficiency and Autoimmune Thyroid Diseases


Tinatin Kacharava*, Elene Giorgadze, Shota Janjgava, Nino Lomtadze and Taboridze Iamze


DOI: 10.2174/1871530322666220627145635
View Abstract


Heavy Metal Pollution and Male Fertility: An Overview on Adverse Biological Effects and Socio-Economic Implications


Felice Crocetto, Rossella Risolo, Rita Colapietro, Rosa Bellavita, Biagio Barone, Andrea Ballini*, Roberto Arrigoni*, Vincenzo Francesco Caputo, Giovanni Luca, Paolo Grieco, Giunio Santini and Stefano Brancorsini


DOI: 10.2174/1871530322666220627141651
View Abstract


Neurobiological Correlates Shared Between Obesity, BED and Food Addiction


Walter Milano, Francesca Carizzone, Valeria De Biasio, Maria Angela Mercorio, Maria Francesca Milano, Biancamaria Saetta and Anna Capasso*


DOI: 10.2174/1871530322666220627125642
View Abstract


Microbiome Medicine: Microbiota in Development and Management of Cardiovascular Diseases


Yogesh Garg, Navjot Kanwar, Hemraj Dodiya, Shruti Chopra, Murtaza Tambuwala, Amit Bhatia* and Abhinav Kanwal*


DOI: 10.2174/1871530322666220624161712
View Abstract


Antioxidant and hepatoprotective activities of Acacia jacquemontii stem extract against high-fat and CCl4 induced liver injury in rat's model


Maria Daud*, Wafa Majeed*, Alishbah Roobi, Ambreen Mehmood Awan, Bilal Aslam, Muhammad Abdullah, Mahnoor Syed, Hafsa Iqbal, Hafiza Arooj Kanwal and Noreen Aslam


DOI: 10.2174/1871530322666220623122633
View Abstract




A Case Report of Concurrent Graves' Disease and Subacute Thyroiditis Following SARS-CoV-2 Vaccination: An Autoimmune/Inflammatory Syndrome (ASIA)


Işılay Taşkaldıran*, Feride Pınar Altay, Yusuf Bozkuş, Özlem Turan İyidir, Aslı Nar and Neslihan Başçıl Tütüncü


DOI: 10.2174/1871530322666220621101209
View Abstract



Published Contents

Editor's Choice



Can Cytokines be used as an Activation Marker in Rheumatoid Arthritis?

, 2021; 21(8): 1459 - 1465

Fatih Öner Kaya, Yeşim Ceylan, Belkız Öngen İpek, Zeynep Güneş Özünal, Gülbüz Sezgin and Selim Nalbant*


DOI: 10.2174/1871530320666201019115030



Benfotiamine Reduces Dendritic Cell Inflammatory Potency

, 2021; 21(7): 1344 - 1351

Neda Djedovic, Iva Božić, Đorđe Miljković* and Irena Lavrnja


DOI: 10.2174/1871530320999200905114135



Acute Versus Chronic Administration of Calcineurin-Inhibitors Differentially Affect T-Cell Function

, 2021; 21(6): 1083 - 1089

Julia Kirchhof, Benjamin Wilde*, Justine Schmidt, Nils Mülling, Liubov Petrakova, Alexandra Brinkhoff, Manfred Schedlowski and Oliver Witzke


DOI: 10.2174/1871530320999200831161710



The Effects of Pemafibrate in Japanese Patients with Type 2 Diabetes Receiving HMG-CoA Reductase Inhibitors

, 2021; 21(5): 919 - 924

Masataka Kusunoki*, Takahiko Sakazaki, Kazuhiko Tsutsumi, Tetsuro Miyata and Yoshiharu Oshida


DOI: 10.2174/1871530320999200818135553



Downregulation of miR-140 is Correlated with Poor Prognosis and Progression of Thyroid Cancer

, 2021; 21(4): 749 - 755

Qianqian Yu, Wenhai Sun, Hui Hua, Yulian Chi, Xiaomin Liu, Anbing Dong, Yinghe Sun, Jianhua Zhang and Ge Guan*


DOI: 10.2174/1871530320666200724180742



T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis

, 2021; 21(3): 495 - 503

Mohammad R. Monjezi, Hamed Fouladseresht, Shirin Farjadian, Behrouz Gharesi-Fard, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530320666200505115850



Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men

, 2021; 21(2): 338 - 344

Reza Afrisham, Maliheh Paknejad, Davod Ilbeigi, Sahar Sadegh-Nejadi, Sattar Gorgani-Firuzjaee* and Mahmoud Vahidi*


DOI: 10.2174/1871530320666200601164253




Open Access Articles

The Skeletal Effects of Gonadotropin-Releasing Hormone Antagonists: A Concise Review

, 2021; 21(10): 1713 - 1720

Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana and Kok-Yong Chin*




How Much Vitamin D is Too Much? A Case Report and Review of the Literature

, 2021; 21(9): 1653 - 1659

Sara De Vincentis*, Antonino Russo, Marta Milazzo, Amedeo Lonardo, Maria C. De Santis, Vincenzo Rochira, Manuela Simoni and Bruno Madeo




False Positive of <sup>68</sup>Ga-DOTATATE PET-CT in a Paraganglioma

, 2021; 21(7): 1352 - 1355

Benedetta Zampetti, Roberto Attanasio*, Marco Boniardi and Renato Cozzi




Effects of a Low Carb Diet and Whey Proteins on Anthropometric, Hematochemical, and Cardiovascular Parameters in Subjects with Obesity

, 2020; 20(10): 1719 - 1725

Giovanni De Pergola*, Roberta Zupo, Luisa Lampignano, Silvia Paradiso, Isanna Murro, Annagrazia Cecere, Nicola Bartolomeo, Marco M. Ciccone, Gianluigi Giannelli and Vincenzo Triggiani





The Association between Peripheral Blood Cells and the Frailty Syndrome in Patients with Cardiovascular Diseases

, 2020; 20(9): 1419 - 1433

Constantin Bodolea, Elisabeta I. Hiriscau*, Elena-Cristina Buzdugan, Alin I. Grosu, Laurențiu Stoicescu, Ștefan Vesa and Omar Cauli




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 2: Therapeutic Issues

, 2020; 20(8): 1144 - 1155

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues

, 2020; 20(8): 1133 - 1143

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson




Exercise and Stevia Rebaudiana (R) Extracts Attenuate Diabetic Cardiomyopathy in Type 2 Diabetic Rats: Possible Underlying Mechanisms

, 2020; 20(7): 1117 - 1132

Abdelaziz M. Hussein*, Elsayed A. Eid, Ismaeel Bin-Jaliah, Medhat Taha and Lashin S. Lashin




Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway

, 2020; 20(5): 771 - 780

Shuang Yao, Jun Zhang, Yuxia Zhan, Yuanping Shi, Yang Yu, Lu Zheng, Ning Xu* and Guanghua Luo*




Future Perspective of Diabetic Animal Models

, 2020; 20(1): 25 - 38

Shashank Pandey and Magdalena C. Dvorakova*




Pioglitazone Therapy and Fractures: Systematic Review and Meta- Analysis

, 2018; 18(5): 502 - 507

Velichka Pavlova*, Elena Filipova, Katya Uzunova, Krassimir Kalinov and Toni Vekov




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Assessment of Response to Treatment and Follow-Up in Gastroenteropancreatic Neuroendocrine Neoplasms

, 2018; 18(5): 419 - 449

Franco Grimaldi*, Nicola Fazio*, Roberto Attanasio, Andrea Frasoldati, Enrico Papini, Nadia Cremonini, Maria V. Davi, Luigi Funicelli, Sara Massironi, Francesca Spada, Vincenzo Toscano, Annibale Versari, Michele Zini, Massimo Falconi and Kjell Oberg




Shift from Levothyroxine Tablets to Liquid Formulation at Breakfast Improves Quality of Life of Hypothyroid Patients

, 2018; 18(3): 235 - 240

Rinaldo Guglielmi, Franco Grimaldi, Roberto Negro, Andrea Frasoldati, Irene Misischi, Filomena Graziano, Claudia Cipri, Edoardo Guastamacchia, Vincenzo Triggiani* and Enrico Papini




GH Supplementation Effects on Cardiovascular Risk in GH Deficient Adult Patients: A Systematic Review and Meta-analysis

, 2017; 17(4): 285 - 296

Vito A. Giagulli*, Marco Castellana, Raffaella Perrone, Edoardo Guastamacchia, Massimo Iacoviello and Vincenzo Triggiani





Most Cited Articles


Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352



Research Article

Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo- controlled study

, 2019; 19(2): 136-143.

Vincenzo Mollace*, Miriam Scicchitano, Sara Paone, Francesca Casale, Carla Calandruccio, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Saverio Nucera, Antonella Riva, Pietro Allegrini, Massimo Ronchi, Giovanna Petrangolini and Ezio Bombardelli


DOI: 10.2174/1871530319666181203151513


Review Article

BPA and nutraceuticals, simultaneous effects on endocrine functions

, 2019; 19(5): 594-604.

Stefania D'Angelo, Marika Scafuro and Rosaria Meccariello*


DOI: 10.2174/1871530319666190101120119


Clinical Trial

The neuromodulatory effects of ω-3 fatty acids and nano-curcumin on the COX-2/ iNOS network in migraines: A clinical trial study from gene expression to clinical symptoms

, 2019; 19(6): 874-884.

Mina Abdolahi, Arash Jafarieh, Payam Sarraf, Mohsen Sedighiyan, Abolghasem Yousefi, Abbas Tafakhori, Hamed Abdollahi, Farahnaz Salehinia and Mahmoud Djalali*


DOI: 10.2174/1871530319666190212170140


Research Article

Evaluation of TG-HDL ratio instead of HOMA ratio as insulin resistance marker in overweight and children with obesity

, 2019; 19(5): 676-682.

Eman G. Behiry*, Nazih Mohamed El Nady, Omima M. AbdEl Haie, May Kamel Mattar and Amira Magdy


DOI: 10.2174/1871530319666190121123535


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344


General Research Article

25 hydroxyvitamin D levels are negatively and independently associated with fat mass in a cohort of healthy overweight and obese subjects

, 2019; 19(6): 838-844.

Giovanni De Pergola*, Tommaso Martino, Roberta Zupo, Domenico Caccavo, Claudio Pecorella, Silvia Paradiso, Franco Silvestris and Vincenzo Triggiani


DOI: 10.2174/1871530319666190122094039


Research Article

Anti-cancerous effect of rutin against HPV-C33A cervical cancer cells via g0/g1 cell cycle arrest and apoptotic induction

, 2020; 20(3): 409-418.

Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257


General Research Article

Elucidation of the chemopreventive role of stigmasterol against Jab1 in gall bladder carcinoma

, 2019; 19(6): 826-837.

Pratibha Pandey, Preeti Bajpai*, Mohammad H. Siddiqui, Uzma Sayyed, Rohit Tiwari, Rafia Shekh, Kumudesh Mishra and V.K. Kapoor


DOI: 10.2174/1871530319666190206124120


Review Article (Mini-Review)

Quality of life in individuals with diabetic foot syndrome

, 2020; 20(9): 1365-1372.

Emmanuel Navarro-Flores and Omar Cauli*


DOI: 10.2174/1871530320666200128154036



Research Article

Overexpression of hepassocin in diabetic patients with nonalcoholic fatty liver disease may facilitate increased hepatic lipid accumulation

, 2019; 19(2): 185-188.

Ghada Abdelmoemen, Samy Abdelkader Khodeir, Ahmed Nabil Zaki, Maha Kassab, Sabry Abou-Saif and Sherief Abd-Elsalam*


DOI: 10.2174/1871530318666180716100543


Research Article

Sex-specific association between serum uric acid and elevated alanine aminotransferase in a military cohort: The chief study

, 2019; 19(3): 333-340.

Jia-Wei Lin, Kun-Zhe Tsai, Kai-Wen Chen, Fang-Ying Su, Yi-Hwei Li, Yen-Po Lin, Chih-Lu Han, Felicia Lin, Yu-Kai Lin, Chung-Bao Hsieh and Gen-Min Lin*


DOI: 10.2174/1871530319666181129163802



Most Accessed Articles

Rebalancing the Oral Microbiota as an Efficient Tool in Endocrine, Metabolic and Immune Disorders

, 2021; 21(5): 777-784.

Isacco, Ciro Gargiulo; Ballini, Andrea; De Vito, Danila; Kieu Cao Diem Nguyen; Cantore, Stefania; Bottalico, Lucrezia; Quagliuolo, Lucio; Boccellino, Mariarosaria; Di Domenico, Marina; Santacroce, Luigi; Arrigoni, Roberto; Dipalma, Gianna; Inchingolo, Francesco


DOI: 10.2174/1871530320666200729142504



A Review of AEG-1 Oncogene Regulating MicroRNA Expression in Colon Cancer Progression

, 2021; 21(1): 27-34.

Malayaperumal, Sarubala; Sriramulu, Sushmitha; Jothimani, Ganesan; Banerjee, Antara; Pathak, Surajit


DOI: 10.2174/1871530320666200618104116


Tanta Protocol for Management of COVID-19: Perspectives from a Devel- oping Country

, 2021; 21(10): 1775-1780.

Abd-Elsalam, Sherief; Esmail, Eslam Saber; Khalaf, Mai; El-Sarnagawy, Ghada N.; Shalaby, Shahinaz M.; Ghafar, Mohamed Samir Abd El; Elbahnasawy, Mohamed; Elfert, Asem; Soliman, Hanan; El-kalla, Ferial; Ghoneim, Ahmed


DOI: 10.2174/1871530320999201117142305






Clinical, Immunologic and Molecular Spectrum of Patients with Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome: A Systematic Review

, 2021; 21(4): 664-672.

Kiaee, Fatemeh; Zaki-Dizaji, Majid; Hafezi, Nasim; Almasi-Hashiani, Amir; Hamedifar, Haleh; Sabzevari, Araz; Shirkani, Afshin; Zian, Zeineb; Jadidi-Niaragh, Farhad; Aghamahdi, Fatemeh; Goudarzvand, Mahdi; Yazdani, Reza; Abolhassani, Hassan; Aghamohammadi, Asghar; Azizi, Gholamreza


DOI: 10.2174/1871530320666200613204426



Coronaviruses and Endocrine System: A Systematic Review on Evidence and Shadows

, 2021; 21(7): 1242-1251.

Parolin, Matteo; Parisotto, Matteo; Zanchetta, Francesca; Sartorato, Paola; De Menis, Ernesto


DOI: 10.2174/1871530320666200905123332



The Cannabis Spread throughout the Continents and its Therapeutic Use in History

, 2021; 21(3): 407-417.

Charitos, Ioannis A.; Gagliano-Candela, Roberto; Santacroce, Luigi; Bottalico, Lucrezia


DOI: 10.2174/1871530320666200520095900


Historical Anecdotes and Breakthroughs of Histamine: From Discovery to Date

, 2021; 21(5): 801-814.

Charitos, Ioannis A.; Castellaneta, Francesca; Santacroce, Luigi; Bottalico, Lucrezia


DOI: 10.2174/1871530320666200729150124


Theranostic Nanoparticles for Pancreatic Cancer Treatment

, 2021; 21(2): 203-214.

Jaidev, Leela R.; Chede, Laxmi S.; Kandikattu, Hemanth K.


DOI: 10.2174/1871530320666200516164911




Editor-in-Chief

graphic
Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
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Society Name: The official Journal of Associazione Medici Endocrinologi

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