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Current Pharmaceutical Design

Volume 27, 46 Issues, 2021
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth reviews/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 27

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Number 29





Review Article (Mini-Review)

Gender Disparities in the Prevalence, Awareness, Treatment, and Control of High Blood Pressure

, 27(29): 3173 - 3179

Maria Dorobantu, Oana-Florentina Gheorghe-Fronea*, Alexandru Scafa-Udriste, Sebastian Onciul, Calin Pop, Lucian Dorobantu and Roxana Darabont


DOI: 10.2174/1381612827666210125154749


Review Article (Mini-Review)

Sex Differences in Clinical Outcomes of Patients with Stable Coronary Artery Disease after Percutaneous Coronary Intervention

, 27(29): 3180 - 3185

Emmanuel P. Vardas, Evangelos Oikonomou, Gerasimos Siasos, Panagiotis Theofilis, Polychronis Dilaveris, Angelos Papanikolaou and Dimitris Tousoulis*


DOI: 10.2174/1381612827666210303142901




Review Article

Gender Differences in Non-Obstructive Coronary Artery Disease

, 27(29): 3198 - 3209

Maria Bergami, Marialuisa Scarpone, Edina Cenko, Elisa Varotti, Peter L. Amaduzzi and Olivia Manfrini*


DOI: 10.2174/1381612826666201012163845


Review Article

Gender Disparities on Access to Care and Coronary Disease Management

, 27(29): 3210 - 3220

Zorana Vasiljevic-Pokrajcic*, Gordana Krljanac, Ratko Lasica, Marija Zdravkovic, Sanja Stankovic, Predrag Mitrovic, Vladan Vukcevic and Milika Asanin


DOI: 10.2174/1381612827666210406144310


Review Article

Myocardial Infarction in Systemic Lupus Erythematosus – the Sex-Specific Risk Profile

, 27(29): 3221 - 3228

Marija Vavlukis*, Daniela Pop-Gjorcevab, Lidija Poposka, Emilija Sandevska and Sasko Kedev


DOI: 10.2174/1381612826666201210110809


Review Article

Impact of Sex on Office White Coat effect Tail: A Review

, 27(29): 3229 - 3234

Xavier Humbert*, Sophie Fedrizzi, Agnès Hofferer, Mathieu Bansard, Anne-Laure Huet, Christiane Bedier, Andry Rabiaza, Jeanne L. Bas, François L. Bas, Joachim Alexandre and Paolo E. Puddu


DOI: 10.2174/1381612827999210112204306


Current Pharmaceutical Design, Volume 27 (2021) - Number 36


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 35


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 34


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 33


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 32


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 31


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Design, Volume 27 (2021) - Number 30


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



The Therapeutic Value and Molecular Mechanisms of lncRNA FENDRR in Human Cancer


Wen Xu, Bei Wang, Yuxuan Cai, Jinlan Chen, Enqing Meng, Chong Guo, Gang Zhou* and Chengfu Yuan*


DOI: 10.2174/1381612827666210820094702
View Abstract View on PubMed





RYR1-Related Rhabdomyolysis: A Spectrum of Hypermetabolic States Due to Ryanodine Receptor Dysfunction


Nick Kruijt*, Luuk Van den Bersselaar, Marc Snoeck, Kees Kramers, Sheila Riazi, Coen Bongers, Susan Treves, Heinz Jungbluth and Nicol Voermans


DOI: 10.2174/1381612827666210804095300
View Abstract View on PubMed


Contraindications Differ Widely Among Beta Blockers and Ought to be Cited for an Individual Drug, Not for the Entire Class


Goran Koraćević , Milovan Stojanović *, Tomislav Kostić , Dragan Lović, Marija Zdravković, Maja Koraćević, Dimitrije Pavlović and Slađana Mićić


DOI: 10.2174/1381612827666210716162130
View Abstract View on PubMed




Abstracts Ahead of Print

Headache in multiple sclerosis - pharmacological aspects


Marcel Gebhardt*, Peter Kropp, Frank Hoffmann and Uwe K. Zettl


DOI: 10.2174/1381612827666210922114100
View Abstract



Dermoprotective effects of saffron: A mini review


Hamid Rigi, Leila Mohtashami, Maryam Asnaashari and Zahra Tayarani-Najaran*


DOI: 10.2174/1381612827666210920150855
View Abstract


BDZs, designer BDZs, and Z-drugs: pharmacology and misuse insights


Simona Zaami, Silvia Graziano, Roberta Tittarelli, Renata Beck and Enrico Marinelli*


DOI: 10.2174/1381612827666210917145636
View Abstract



Recent Advances in Theranostic Applications of Nanomaterials in Cancer


Faraha Ahmed, Mohammad Ahmed Khan*, Nafis Haider, Mohammad Zaki Ahmad and Javed Ahmad*


DOI: 10.2174/1381612827666210916140627
View Abstract





Outer Membrane Vesicles of Bordetella pertussis encapsulated into sodium alginate nanoparticles as novel vaccine delivery system


Abbas Rami, Fatemeh Kazemi-Lomedasht, Ali Mirjalili, Mojtaba Noofeli, Fereshteh Shahcheraghi* and Naser Mohammadpour Dounighi*


DOI: 10.2174/1381612827666210907154715
View Abstract


Published Contents

Editor's Choice

Sex Differences in Clinical Outcomes of Patients with Stable Coronary Artery Disease after Percutaneous Coronary Intervention

, 2021; 27(29): 3180 - 3185

Emmanuel P. Vardas, Evangelos Oikonomou, Gerasimos Siasos, Panagiotis Theofilis, Polychronis Dilaveris, Angelos Papanikolaou and Dimitris Tousoulis*


DOI: 10.2174/1381612827666210303142901









Prevalence of Non-coronary Heart Disease in Patients with Familial Hypercholesterolemia: An Analysis from the HELLAS-FH

, 2021; 27(21): 2537 - 2544

Panagiotis Anagnostis, Christos V. Rizos, Ioannis Skoumas, Loukianos Rallidis, Konstantinos Tziomalos, Emmanuel Skalidis, Vasileios Kotsis, Michalis Doumas, Genovefa Kolovou, George Sfikas, Eleni Bilianou, Iosif Koutagiar, Dimitrios Agapakis, Evangelos Zacharis, Christina Antza, Charalambos Koumaras, Chrysoula Boutari, George Liamis and Evangelos N. Liberopoulos*


DOI: 10.2174/1381612827666210216151645



Quercetin and MicroRNA Interplay in Apoptosis Regulation in Ovarian Cancer

, 2021; 27(20): 2328 - 2336

Khushbukhat Khan, Zeeshan Javed*, Haleema Sadia, Javad Sharifi-Rad*, William C. Cho * and Claudio Luparello*


DOI: 10.2174/1381612826666201019102207




Open Access Articles


Exosome Limitations in the Treatment of Inflammatory Diseases

, 2021; 27(28): 3105 - 3121

Daria Skuratovskaia*, Maria Vulf, Olga Khaziakhmatova, Vladimir Malashchenko, Aleksandra Komar, Egor Shunkin, Natalia Gazatova and Larisa Litvinova




Marine Bioactive Peptides in Supplements and Functional Foods - A Commercial Perspective

, 2021; 27(11): 1353 - 1364

Ragnhild Dragøy Whitaker*, Themis Altintzoglou, Kjersti Lian and Estefania Noriega Fernandez




Anti-malarial Drugs are Not Created Equal for SARS-CoV-2 Treatment: A Computational Analysis Evidence

, 2021; 27(10): 1323 - 1329

Simone Ronsisvalle, Federica Panarello, Rosaria Di Mauro, Renato Bernardini, Giovanni Li Volti* and Giuseppina Cantarella




Effects of an Integrative Mind-Body-Medicine Group Program on Breast Cancer Patients During Chemotherapy: An Observational Study

, 2021; 27(8): 1112 - 1120

Heidemarie Haller, Kyung-Eun Choi, Silke Lange, Sherko Kümmel, Anna Paul, Holger Cramer, Gustav Dobos and Petra Voiss*









The Pathogenic Subpopulation of Th17 Cells in Obesity

, 2021; 27: 1 - 15 (E-Pub Ahead of Print)

Natalia Todosenko, Maria Vulf*, Kristina Yurova, Daria Skuratovskaia, Olga Khaziakhmatova, Natalia Gazatova, Olga Melashchenko, Olga Urazova and Larisa Litvinova*




Treatment of Anderson-Fabry Disease

, 2020; 26(40): 5089 - 5099

Irene Simonetta*, Antonino Tuttolomondo, Mario Daidone, Salvatore Miceli and Antonio Pinto





Nanostructured Lipid Carriers as Potential Drug Delivery Systems for Skin Disorders

, 2020; 26(36): 4569 - 4579

Tejashree Waghule, Vamshi Krishna Rapalli, Srividya Gorantla, Ranendra Narayan Saha, Sunil Kumar Dubey, Anu Puri and Gautam Singhvi*




A New Look at an Old Drug: Cumulative Effects of Low Ribavirin Doses in Amphetamine-Sensitized Rats

, 2020; 26(31): 3884 - 3894

Branka Petković*, Srđan Kesić, Slavica Ristić, Željko Pavković, Jelena Podgorac, Gordana Stojadinović and Vesna Pešić





Most Cited Articles

General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506


Review Article

Pollution, toxicity and carcinogenicity of organic dyes and their catalytic bio-remediation

, 2019; 25(34): 3645-3663.

Muhammad Ismail, Kalsoom Akhtar, M.I. Khan, Tahseen Kamal, Murad A. Khan, Abdullah M. Asiri, Jongchul Seo and Sher B. Khan*


DOI: 10.2174/1381612825666191021142026


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424


Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541



General Review Article

Ethnobotany, phytochemistry and traditional uses of curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): A Review

, 2019; 25(8): 871-935.

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Review Article

Metal/metal oxide nanoparticles: Toxicity, applications, and future prospects

, 2019; 25(37): 4013-4029.

Ratiram G. Chaudhary*, Ganesh S. Bhusari, Ashish D. Tiple, Alok R. Rai, Subhash R. Somkuvar, Ajay K. Potbhare, Trimurti L. Lambat, Prashant P. Ingle and Ahmed A. Abdala*


DOI: 10.2174/1381612825666191111091326


Review Article

Composition and potential health benefits of pomegranate: A review

, 2019; 25(16): 1817-1827.

Vesna Vučić*, Milkica Grabež, Armen Trchounian and Aleksandra Arsić


DOI: 10.2174/1381612825666190708183941


Review Article

Expression profile of MicroRNA: An emerging hallmark of cancer

, 2019; 25(6): 642-653.

Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


DOI: 10.2174/1386207322666190325122821






Most Accessed Articles

Exosome Limitations in the Treatment of Inflammatory Diseases

, 2021; 27(28): 3105-3121.

Daria Skuratovskaia*, Maria Vulf, Olga Khaziakhmatova, Vladimir Malashchenko, Aleksandra Komar, Egor Shunkin, Natalia Gazatova and Larisa Litvinova


DOI: 10.2174/1381612826666201210120444



Zacopride Exerts an Antiarrhythmic Effect by Specifically Stimulating the Cardiac Inward Rectifier Potassium Current in Rabbits: Exploration of a New Antiarrhythmic Strategy

, 2020; 26(44): 5746-5754.

Yuanyuan Lin, Junhu Li, Baozhong Zhu, Qinghua Liu, Xiaojie Bai, Bingmei Chang, Yanlin Guo, Qilong Feng*, Xuewen Li*, Bowei Wu and Jimin Cao


DOI: 10.2174/1381612826666200701135508


An Overview of Targeting Legumain for Inhibiting Cancers

, 2021; 27(31): 3337-3348.

Bandi Deepa Reddy, Narasimha M Beeraka, CH. M. Kumari Chitturi and SubbaRao V. Madhunapantula*


DOI: 10.2174/1381612826666201125111625



Silybin B and Cianidanol Inhibit Mpro and Spike Protein of SARS-CoV-2: Evidence from in silico Molecular Docking Studies

, 2021; 27(32): 3476-3489.

Rashi Srivastava, Shubham Tripathi, Sreepoorna Pramodh, Arif Hussain, Shafiul Haque, Nandita Dasgupta, Vineeta Singh* and Bhartendu Nath Mishra*


DOI: 10.2174/1381612826666201210122726



Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential

, 2021; 27(34): 3591-3601.

Nimra Javaid, Muhammad A. Shah*, Azhar Rasul, Zunera Chauhdary, Uzma Saleem, Haroon Khan, Nazir Ahmed, Md. Sahab Uddin, Bijo Mathew, Tapan Behl and Renald Blundell


DOI: 10.2174/1381612826666201112144006


Nutrition and NSCLC; Should We Administer Food Supplements?

, 2021; 27(34): 3602-3608.

Paul Zarogoulidis*, Christoforos Kosmidis, Isaak Kesisoglou, Kosmas Tsakiridis, Wolfgang Hohenforst-Schmidt, Haidong Huang, Κonstantinos Romanidis, Anastasios Vagionas and Konstantinos Sapalidis


DOI: 10.2174/1381612827999210111193133





In Silico Prediction and Designing of Potential siRNAs to be used as Antivirals Against SARS-CoV-2

, 2021; 27(32): 3490-3500.

Sayed S. Sohrab, Sherif Aly El-Kafrawy, Aymn T. Abbas, Leena H. Bajrai and Esam I. Azhar*


DOI: 10.2174/1381612827999210111194101






Editor-in-Chief

graphic
Alessandro Antonelli
(12,288 citations)
Department of Clinical and Experimental Medicine
Laboratory of Primary Human Cells
University of Pisa
Pisa
(Italy)
Biography
View Full Editorial Board

Executive Editor

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography

Nobel Laureates on Editorial Board

graphic
Andrew V. Schally
(USA)

COPE Compliant

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Journal History

Current Pharmaceutical Design was introduced in 1995. Prof. Alessandro Antonelli serves as the Editor-in-Chief of the journal.

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