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Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 24

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Number 42



Editorial   Open Access



Review Article

3D Printing Methods for Pharmaceutical Manufacturing: Opportunity and Challenges

, 24(42): 4949 - 4956

Musarrat H. Warsi*, Mohammad Yusuf, Majed Al Robaian, Maria Khan, Abdul Muheem and Saba Khan*


DOI: 10.2174/1381612825666181206121701


Review Article



Review Article

Role of Polymers in 3D Printing Technology for Drug Delivery - An Overview

, 24(42): 4979 - 4990

Ankit Jain, Kuldeep K. Bansal*, Ankita Tiwari, Ari Rosling and Jessica M. Rosenholm*


DOI: 10.2174/1381612825666181226160040


Review Article



Review Article

3D Printing Technology in Design of Pharmaceutical Products

, 24(42): 5009 - 5018

Ameeduzzafar, Nabil K. Alruwaili, Md. Rizwanullah, Syed Nasir Abbas Bukhari, Mohd Amir, Muhammad Masood Ahmed and Mohammad Fazil*


DOI: 10.2174/1381612825666190116104620


Review Article



Review Article



Articles Ahead of Print


Cyclodextrins as Carriers in Targeted Delivery of Therapeutic Agents: Focused Review on Traditional and Inimitable Applications


Sushil Yadaorao Raut, Alekhya Sri Nagini Manne, Guruprasad Kalthur, Sanyog Jain and Srinivas Mutalik*


View Abstract View on PubMed



Emerging Therapeutic Targets in Oncologic Photodynamic Therapy


Gina Manda*, Mihail Eugen Hinescu, Ionela Victoria Neagoe, Luis Filipe Vieira Ferreira, Rica Boscencu, Paul Vasos, Selma Huveyda Basaga and Antonio Cuadrado


View Abstract View on PubMed


Evaluation of Local Injection of Bevacizumab against Triple-Negative Breast Cancer Xenograft Tumors


Xin Jiang, Qiao-Li Zhang*, Tie-Gang Liu, Wei-Peng Zhao, Ming Yang, Li-Na Wang, Wei-Liang Sun, Lin Pan, Ai-Ping Luo, Jin-Chang Huang and Xiao-Hong Gu*


View Abstract View on PubMed


Novel Pathways in the Treatment of Major Depression: Focus on the Glutamatergic System


Carmine Tomasetti , Chiara Montemitro, Annastasia L. C. Fiengo , Cristina Santone , Laura Orsolini , Alessandro Valchera, Alessandro Carano, Maurizio Pompili , Gianluca Serafini , Giampaolo Perna, Federica Vellante, Giovanni Martinotti, Massimo Di Giannantonio , Yong-Ku Kim, Marco Di Nicola , Antonello Bellomo, Antonio Ventriglio , Michele Fornaro and Domenico De Berardis*


View Abstract View on PubMed



Mineralocorticoid Receptor Antagonists in Primary Aldosteronism


Konstantinos Stavropoulos, Christodoulos Papadopoulos, Konstantinos Koutsampasopoulos, Georgios Lales, Christos Mitas and Michael Doumas*


View Abstract View on PubMed



The Relationship between Prostate Cancer and Metformin Consumption: A Systematic Review and Meta-Analysis Study


Bahareh Ghiasi, Diana Sarokhani, Farid Najafi, Morteza Motedayen and Ali Hasanpour Dehkordi*


View Abstract View on PubMed


Abstracts Ahead of Print

Expression profile of MicroRNA: An Emerging Hallmark of Cancer


Uzma Zaheer, Muhammed Faheem, Ishtiaq Qadri, Nargis Begum, Hadi M. Yassine, Asmaa A. Al Thani and Shilu Mathew*


View Abstract



Women’s Beliefs about Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists?


Michael Ceulemans*, Angela Lupattelli , Hedvig Nordeng , Marina Odalovic, Michael Twigg and Veerle Foulon


View Abstract


Stimuli-responsive Drug Delivery Systems as an Emerging Platform for Treatment of Rheumatoid Arthritis


Xiao-Ling Xu, Kong-Jun Lu, Xiao-Qin Yao, Xiao-Ying Ying and Yong-Zhong Du*


View Abstract


Non-clinical Models to Determine Drug Passage into Human Breast Milk


Domenico Ventrella, Monica Forni, Maria Laura Bacci and Pieter Annaert*


View Abstract



Next Generation Medical Management of Postpartum Hemorrhage


Jaclyn M. Phillips, John N. van den Anker and Homa K. Ahmadzia*


View Abstract


Sildenafil for Antenatal Treatment of Congenital Diaphragmatic Hernia: from Bench to Bedside


Francesca M. Russo, Felix De Bie, Ryan Hodges, Alan Flake and Jan Deprest*


View Abstract


Mobile health applications for prenatal assessment and monitoring


Wilfried Gyselaers*, D Lanssens , H Perry and A Khalil


View Abstract


Clinical Pharmacokinetic Studies in Pregnant Women and the Relevance of Pharmacometric Tools


André Dallmann*, Paola Mian, Johannes Van den Anker and Karel Allegaert


View Abstract


Editor's Choice

Role of Polymers in 3D Printing Technology for Drug Delivery - An Overview

, 2018; 24(42): 4979 - 4990

Ankit Jain, Kuldeep K. Bansal*, Ankita Tiwari, Ari Rosling and Jessica M. Rosenholm*


DOI: 10.2174/1381612825666181226160040





The Role of TGF-β Signaling Regulatory MicroRNAs in the Pathogenesis of Colorectal Cancer

, 2018; 24(39): 4611 - 4618

Reyhaneh Moradi-Marjaneh, Majid Khazaei, Gordon A. Ferns and Seyed H. Aghaee-Bakhtiari*


DOI: 10.2174/1381612825666190110150705



Rivaroxaban versus Clopidogrel for Peripheral Artery Disease: A Clinico-Economic Approach of the COMPASS Trial

, 2018; 24(38): 4516 - 4517

Diamantis I. Tsilimigras, Demetrios Moris*, Georgios Karaolanis, Stavros K. Kakkos, Konstantinos Filis and Fragiska Sigala


DOI: 10.2174/1381612825666190101100832



Circulating Exosomes as Potential Biomarkers in Cardiovascular Disease

, 2018; 24(37): 4436 - 4444

Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, Maryam Ghandehari, Seyed Mohammad Reza Parizadeh, Seyed Mahdi Hassanian, Majid Rezayi, Majid Ghayour-Mobarhan, Gordon A. Ferns and Amir Avan*


DOI: 10.2174/1381612825666181219162655



Potential of Natural-Based Anticancer Compounds for P-Glycoprotein Inhibition

, 2018; 24(36): 4334 - 4354

Jelena Dinić, Ana Podolski-Renić, Marko Jeremić and Milica Pešić*


DOI: 10.2174/1381612825666190112164211



Protective Mechanisms of Butyrate on Inflammatory Bowel Disease

, 2018; 24(35): 4154 - 4166

João P.B. Silva, Kely C. Navegantes-Lima, Ana L.B. Oliveira, Dávila V.S. Rodrigues, Sílvia L.F. Gaspar, Valter V.S. Monteiro, Davi P. Moura and Marta C. Monteiro*


DOI: 10.2174/1381612824666181001153605





Open Access Articles

Novel Data on the Prevalence, Identification, Scouting, and Treatment of Familial Hypercholesterolaemia

, 2018; 24(31): 3597 - 3598

Michael Doumas, Konstantinos Imprialos, Konstantinos Stavropoulos and Vasilios G. Athyros





Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

, 2018; 24(26): 3143 - 3151

Alexander N. Orekhov*, Yumiko Oishi , Nikita G. Nikiforov, Andrey V. Zhelankin, Larisa Dubrovsky, Igor A. Sobenin, Alexander Kel, Daria Stelmashenko, Vsevolod J. Makeev, Kathy Foxx, Xueting Jin, Howard S. Kruth and Michael Bukrinsky




Novel Technologies for Dipeptide Drugs Design and their Implantation

, 2018; 24(26): 3020 - 3027

Tatiana A. Gudasheva*, Rita U. Ostrovskaya and Sergey B. Seredenin




Next-generation Metabolomics in the Development of New Antidepressants: Using Albiflorin as an Example

, 2018; 24(22): 2530 - 2540

Jian Han, Yonghong Xia, Lejun Lin, Zuoguang Zhang, Hui Tian and Kefeng Li*





Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

, 2018; 24(18): 2012 - 2022

Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*




Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach

, 2018; 24(13): 1366 - 1376

Mark McCully, Macarena Sanchez-Navarro , Meritxell Teixido* and Ernest Giralt*




Development of Peptide Vaccines in Dengue

, 2018; 24(11): 1157 - 1173

Kavita Reginald, Yanqi Chan, Magdalena Plebanski and Chit Laa Poh*





Virtual Screening and Statistical Analysis in the Design of New Caffeine Analogues Molecules with Potential Epithelial Anticancer Activity

, 2018; 24(5): 576 - 594

Josivan da Silva Costa*, Karina da Silva Lopes Costa, Josiane Viana Cruz, Ryan da Silva Ramos, Luciane Barros Silva, Davi Do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos and Williams Jorge da Cruz Macedo






IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development

, 2017; 23(38): 5964 - 5970

Ann Hellstrom*, David Ley, Boubou Hallberg, Chatarina Lofqvist, Ingrid Hansen-Pupp, Luca A. Ramenghi, Jan Borg, Lois E. H. Smith and Anna-Lena Hard




A Special Focus on Selexipag - Treatment of Pulmonary Arterial Hypertension

, 2017; 23(34): 5191 - 5199

Louise M. Sorensen, Markus Wehland, Marcus Kruger, Ulf Simonsen, Mohamed Z. Nassef, Manfred Infanger and Daniela Grimm*





Most Cited Articles

Autism: Pathophysiology and Promising Herbal Remedies

, 2016; 22(3): 277-285.

Mahmoud Bahmani, Amir Sarrafchi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei


DOI: 10.2174/1381612822666151112151529


Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature

, 2016; 22(1): 28-51.

Paolo Giorgini, Paolo Di Giosia, Davide Grassi, Melvyn Rubenfire, Robert D. Brook and Claudio Ferri


DOI: 10.2174/1381612822666151109111712



Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

, 2016; 22(34): 5257-5269.

Hamid Reza Mirzaei, Amirhossein Sahebkar, Mohsen Mohammadi, Reza Yari, Hossein Salehi, Mohammad Hasan Jafari, Afshin Namdar, Ehsan Khabazian, Mahmoud Reza Jaafari and Hamed Mirzaei


DOI: 10.2174/1381612822666160303110838


The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment

, 2016; 22(3): 397-403.

Sharareh Gholamin, Alireza Pasdar, Mohammad Sadegh Khorrami, Hamed Mirzaei, Hamid Reza Mirzaei, Rasoul Salehi, Gordon A. Ferns, Majid Ghayour-Mobarhan and Amir Avan


DOI: 10.2174/1381612822666151112151924


Computer Aided Drug Design: Success and Limitations

, 2016; 22(5): 572-581.

Mohammad Hassan Baig, Khurshid Ahmad, Sudeep Roy, Jalaluddin Mohammad Ashraf, Mohd Adil, Mohammad Haris Siddiqui, Saif Khan, Mohammad Amjad Kamal, Ivo Provazník and Inho Choi


DOI: 10.2174/1381612822666151125000550


Herba Epimedii: An Ancient Chinese Herbal Medicine in the Prevention and Treatment of Osteoporosis

, 2016; 22(3): 328-349.

Lili Wang, Yu Li, Yubo Guo, Rufeng Ma, Min Fu, Jianzhao Niu, Sihua Gao and Dongwei Zhang


DOI: 10.2174/1381612822666151112145907


From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy

, 2016; 22(34): 5270-5293.

Andreas H. Laustsen, Mikael Engmark, Christina Milbo, Jónas Johannesen, Bruno Lomonte, José María Gutiérrez and Brian Lohse


DOI: 10.2174/1381612822666160623073438




Most Accessed Articles

Where is the Clinical Breakthrough of Heme Oxygenase-1 / Carbon Monoxide Therapeutics?

, 2018; 24(20): 2264-2282.

Christopher P. Hopper, Lorenz Meinel, Christoph Steiger* and Leo E. Otterbein*


DOI: 10.2174/1381612824666180723161811



Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847


Reversal of Novel Anticoagulants in Emergent Surgery and Trauma: A Comprehensive Review and Proposed Management Algorithm

, 2018; 24(38): 4540-4553.

Leonidas Palaiodimos*, Jeremy Miles, Damianos G. Kokkinidis, Christos Barkolias, Anil K. Jonnalagadda, Dimitrios Papaconstantinou, Maximos Frountzas, Evangelos P. Misiakos and Dimitrios Schizas


DOI: 10.2174/1381612825666181226150629




Association of SLCO1B1 Polymorphisms and Atorvastatin Safety and Efficacy: A Meta-analysis

, 2018; 24(34): 4044-4050.

Yaming Du, Sizheng Wang, Zhangyong Chen, Shusen Sun, Zhigang Zhao* and Xingang Li*


DOI: 10.2174/1381612825666181219163534


The Landscape of Protein Tyrosine Phosphatase (Shp2) and Cancer

, 2018; 24(32): 3767-3777.

Ashfaq Ur Rehman, Mueed Ur Rahman, Muhammad T. Khan, Shah Saud, Hao Liu, Dong Song, Pinky Sultana, Abdul Wadood and Hai-Feng Chen*


DOI: 10.2174/1381612824666181106100837




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