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Current Pharmaceutical Design

Volume 28, 46 Issues, 2022
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth reviews/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 28

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Number 4




Review Article (Mini-Review)

Application of Machine Learning Methods for the Development of Antidiabetic Drugs

, 28(4): 260 - 271

Juanjuan Zhao, Pengcheng Xu, Xiujuan Liu, Xiaobo Ji*, Minjie Li, Dev Sooranna, Xiaosheng Qu*, Wencong Lu* and Bing Niu*


DOI: 10.2174/1381612827666210622104428


Review Article



Review Article




General Review Article

Anticoagulation Treatment in Venous Thromboembolism: Options and Optimal Duration

, 28(4): 296 - 305

Stavrianna Diavati , Marios Sagris, Dimitrios Terentes-Printzios* and Charalambos Vlachopoulos


DOI: 10.2174/1381612827666211111150705


Meta-Analysis



General Research Article

Multimodal Targeted Nanoparticle-Based Delivery System for Pancreatic Tumor Imaging in Cellular and Animal Models

, 28(4): 313 - 323

Oula Penate Medina*, Robert J. Tower, Tuula Penate Medina, Fatma Ashkenani, Lia Appold, Marcus Bötcher, Lukas Huber, Olga Will, Qi Ling, Charlotte Hauser, Arndt Rohwedder, Carola Heneweer, Eva Peschke, Jan-Bernd Hövener, Kerstin Lüdtke-Buzug, Susann Boretius , Rolf Mentlein*, Kalevi Kairemo, Claus C. Glüer, Susanne Sebens and Holger Kalthoff


DOI: 10.2174/1381612826666200717084846


Current Pharmaceutical Design, Volume 28 (2022) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


H19: A Vital Long Noncoding RNA in the Treatment of Diabetes and Diabetic Complications


Leiqi Zhu, Yuanyang Li, Fangqi Xia, Mengzhen Xue, Yaqi Wang, Dengke Jia, Yan Gao, Luoying Li, Yue Shi, Silong Chen, Guangfu Xu and Chengfu Yuan*


DOI: 10.2174/1381612827666211210123959
View Abstract View on PubMed






The Regulatory Role of Both MBNL1 and MBNL1-AS1 in Several Common Cancers


Qi Zhang, Yinxin Wu, Jinlan Chen, Fangshun Tan, Jie Mou, Zhuoying Du, Yuxuan Cai, Bei Wang and Chengfu Yuan


DOI: 10.2174/1381612827666210830110732
View Abstract View on PubMed




Role of miRNAs In Cancer Diagnostics and Therapy: A Recent Update


Adil A. Sayyed, Piyush Gondaliya, Palak Bhat, Mukund Mali, Neha Arya*, Amit Khairnar* and Kiran Kalia*


DOI: 10.2174/1381612827666211109113305
View Abstract View on PubMed


Abstracts Ahead of Print

Protective Effect of Panax Notoginseng Saponins on Apolipoprotein-E-deficient Atherosclerosis-prone mice


Yang He, Liu Zuodong, Xiangka Hu, Xiaojuan Liu, Liuming Gui, Zengxiaorui Cai and Chunmei Dai*


DOI: 10.2174/1381612828666220128104636
View Abstract






Therapeutic application of microsponges based drug delivery system


Mahfoozur Rahman, Waleed H Almalki, Sunil K Panda, Aman Kumar Das, Saad Alghamdi, Kirti Soni, Abdul Hafeez, Mayank Handa, Sarwar Beg* and Ziyaur Rahman


DOI: 10.2174/1381612828666220118121536
View Abstract



Effect and mechanism of Lenvatinib@H-MnO2-FA drug delivery system in targeting intrahepatic cholangiocarcinoma


Zhouyu Ning, Lina Yang, Xia Yan, Dan Wang, Yongqiang Hua, Weidong Shi, Junhua Lin and Zhiqiang Meng*


DOI: 10.2174/1381612828666220113161712
View Abstract


PLANT BASED BIOAVAILABILITY ENHANCERS


Sweta Patel, Shruti Chopra, Simran Chaurasia and Maryam Sarwat*


DOI: 10.2174/1381612828666220112141355
View Abstract


Hydrogels for modified-release drug delivery systems


Aleksandra Zielińska, Piotr Eder, Lucas Rannier, Juliana C. Cardoso, Patrícia Severino, Amélia M. Silva and Eliana B. Souto*


DOI: 10.2174/1381612828666211230114755
View Abstract


Published Contents

Editor's Choice





Outer Membrane Vesicles of Bordetella pertussis Encapsulated into Sodium Alginate Nanoparticles as Novel Vaccine Delivery System

, 2021; 27(42): 4341 - 4354

Abbas Rami, Fatemeh Kazemi-Lomedasht, Ali Mirjalili, Mojtaba Noofeli, Fereshteh Shahcheraghi* and Naser M. Dounighi*


DOI: 10.2174/1381612827666210907154715



Anticholinergic Exposure in Elderly Complex Chronic Patients: A Cross-Sectional Study

, 2021; 27(40): 4186 - 4194

Ángela Tristancho-Pérez, Ángela Villalba-Moreno, María D. Santos-Rubio, María D. López-Malo, Bernardo Santos-Ramos and Susana Sánchez-Fidalgo*


DOI: 10.2174/1381612827666210830164054






Hypertension in Pregnancy: Unanswered Questions

, 2021; 27(36): 3795 - 3803

Vasilios Papademetriou *, Konstantinos Stavropoulos , Dimitrios Patoulias, Christodoulos Papadopoulos, Kerpiniotis Georgios, Maria Toumpourleka and Alexandros Sachinidis


DOI: 10.2174/1381612827666210830091652



Open Access Articles

The Pathogenic Subpopulation of Th17 Cells in Obesity

, 2021; 27(37): 3924 - 3938

Natalia Todosenko, Maria Vulf*, Kristina Yurova, Daria Skuratovskaia, Olga Khaziakhmatova, Natalia Gazatova, Olga Melashchenko, Olga Urazova and Larisa Litvinova





Exosome Limitations in the Treatment of Inflammatory Diseases

, 2021; 27(28): 3105 - 3121

Daria Skuratovskaia*, Maria Vulf, Olga Khaziakhmatova, Vladimir Malashchenko, Aleksandra Komar, Egor Shunkin, Natalia Gazatova and Larisa Litvinova




Marine Bioactive Peptides in Supplements and Functional Foods - A Commercial Perspective

, 2021; 27(11): 1353 - 1364

Ragnhild Dragøy Whitaker*, Themis Altintzoglou, Kjersti Lian and Estefania Noriega Fernandez








A New Look at an Old Drug: Cumulative Effects of Low Ribavirin Doses in Amphetamine-Sensitized Rats

, 2020; 26(31): 3884 - 3894

Branka Petković*, Srđan Kesić, Slavica Ristić, Željko Pavković, Jelena Podgorac, Gordana Stojadinović and Vesna Pešić





γ-Aminobutyric Acid and Derivatives Reduce the Incidence of Acute Pain after Herpes Zoster - A Systematic Review and Meta-analysis

, 2020; 26(25): 3026 - 3038

Wuttapon Sadaeng, Katalin Márta, Péter Mátrai, Péter Hegyi, Barbara Tóth, Balázs Németh, László M. Czumbel, Thanyaporn Sang-Ngoen, Zoltán Gyöngyi, Gábor Varga*, Péter Révész, István Szanyi, Kázmér Karádi and Gábor Gerber




Effects of Chlorine Dioxide on Oral Hygiene - A Systematic Review and Meta-analysis

, 2020; 26(25): 3015 - 3025

Beáta Kerémi, Katalin Márta, Kornélia Farkas, László M. Czumbel, Barbara Tóth, Zsolt Szakács, Dezső Csupor, József Czimmer, Zoltán Rumbus, Péter Révész, Adrienn Németh, Gábor Gerber, Péter Hegyi and Gábor Varga*






Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis

, 2020; 26(13): 1417 - 1427

Carolin J. Curtaz, Constanze Schmitt, Kinga G. Blecharz-Lang, Norbert Roewer, Achim Wöckel and Malgorzata Burek*





Most Cited Articles

Review Article

Pollution, toxicity and carcinogenicity of organic dyes and their catalytic bio-remediation

, 2019; 25(34): 3645-3663.

Muhammad Ismail, Kalsoom Akhtar, M.I. Khan, Tahseen Kamal, Murad A. Khan, Abdullah M. Asiri, Jongchul Seo and Sher B. Khan*


DOI: 10.2174/1381612825666191021142026


General Review Article

Long non-coding RNAs as epigenetic regulators in cancer

, 2019; 25(33): 3563-3577.

Asma Vafadar, Zahra Shabaninejad, Ahmad Movahedpour, Soheila Mohammadi, Sima Fathullahzadeh, Hamid R. Mirzaei, Afshin Namdar, Amir Savardashtaki* and Hamed Mirzaei*


DOI: 10.2174/1381612825666190830161528


Review Article

Synthesis of silver nanoparticles and their biomedical applications a comprehensive review

, 2019; 25(24): 2650-2660.

Rajasree Shanmuganathan, Indira Karuppusamy, Muthupandian Saravanan, Harshiny Muthukumar, Kumar Ponnuchamy, Vijayan Sri Ramkumar and Arivalagan Pugazhendhi*


DOI: 10.2174/1381612825666190708185506


Review Article

Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning

, 2019; 25(33): 3519-3535.

Md. Tanvir Kabir, Md. Sahab Uddin*, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George E. Barreto and Ghulam Md. Ashraf


DOI: 10.2174/1381612825666191008103141


Review Article

NMDA receptor antagonists: Repositioning of memantine as a multitargeting agent for Alzheimer's therapy

, 2019; 25(33): 3506-3518.

Md. Tanvir Kabir, Mohammad A. Sufian, Md. Sahab Uddin*, Mst. Marium Begum, Shammi Akhter, Ariful Islam, Bijo Mathew, Md. Siddiqul Islam, Md. Shah Amran and Ghulam Md. Ashraf*


DOI: 10.2174/1381612825666191011102444


Review Article

Alginate nanoparticles for drug delivery and targeting

, 2019; 25(11): 1312-1334.

Patricia Severino, Classius F. da Silva, Luciana N. Andrade, Daniele de Lima Oliveira, Joana Campos and Eliana B. Souto*


DOI: 10.2174/1381612825666190425163424



Review Article

Emerging potential of naturally occurring autophagy modulators against neurodegeneration

, 2020; 26(7): 772-779.

Md. Ataur Rahman*, Md Rezanur Rahman, Toyfiquz Zaman, Md. Sahab Uddin, Rokibul Islam, Mohamed M. Abdel-Daim and Hyewhon Rhim*


DOI: 10.2174/1381612826666200107142541


Review Article

Composition and potential health benefits of pomegranate: A review

, 2019; 25(16): 1817-1827.

Vesna Vučić*, Milkica Grabež, Armen Trchounian and Aleksandra Arsić


DOI: 10.2174/1381612825666190708183941


Review Article

Metal/metal oxide nanoparticles: Toxicity, applications, and future prospects

, 2019; 25(37): 4013-4029.

Ratiram G. Chaudhary*, Ganesh S. Bhusari, Ashish D. Tiple, Alok R. Rai, Subhash R. Somkuvar, Ajay K. Potbhare, Trimurti L. Lambat, Prashant P. Ingle and Ahmed A. Abdala*


DOI: 10.2174/1381612825666191111091326



General Review Article

Ethnobotany, phytochemistry and traditional uses of curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): A Review

, 2019; 25(8): 871-935.

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Review Article

Extracellular vesicles as drug delivery systems - Methods of production and potential therapeutic applications

, 2019; 25(2): 132-154.

Magdalena Surman, Anna Drożdż, Ewa Stępień and Małgorzata Przybyło*


DOI: 10.2174/1381612825666190306153318





Most Accessed Articles

The Pathogenic Subpopulation of Th17 Cells in Obesity

, 2021; 27(37): 3924-3938.

Natalia Todosenko, Maria Vulf*, Kristina Yurova, Daria Skuratovskaia, Olga Khaziakhmatova, Natalia Gazatova, Olga Melashchenko, Olga Urazova and Larisa Litvinova


DOI: 10.2174/1381612826666210101154913


Exosome Limitations in the Treatment of Inflammatory Diseases

, 2021; 27(28): 3105-3121.

Daria Skuratovskaia*, Maria Vulf, Olga Khaziakhmatova, Vladimir Malashchenko, Aleksandra Komar, Egor Shunkin, Natalia Gazatova and Larisa Litvinova


DOI: 10.2174/1381612826666201210120444



Association of Viruses in the Development of Cardiovascular Diseases

, 2021; 27(37): 3913-3923.

Bisma Rauff *, Arif Malik, Yasir A. Bhatti , Shafiq A. Chudhary, Kaneez Fatima, Shafquat Rafiq , Aisha Tahir, Sumaira Sharif and Ishtiaq Qadri


DOI: 10.2174/1381612827666210426094502


Nanotechnology-Based Strategies for the Management of COVID-19: Recent Developments and Challenges

, 2021; 27(41): 4197-4211.

Ritu Singh*, Monalisha Behera, Nisha Kumari, Sanjeev Kumar, Vishnu D. Rajput, Tatiana M. Minkina, Mohd Adnan, Arif J. Siddiqui and Narendra Kumar


DOI: 10.2174/1381612827666210830105459


Lipid Disorders in Pregnancy

, 2021; 27(36): 3804-3807.

Anastasios Liberis*, Stamatis Petousis and Panagiotis Tsikouras


DOI: 10.2174/1381612827666210421103245


Therapeutic Management of COVID-19 Patients: Clinical Manifestation and Limitations

, 2021; 27(41): 4223-4231.

Urooj Fatima, Syed Saif A. Rizvi, Neha Raina, Saher Fatima, Safikur Rahman, Md. Amjad Kamal and Md. Imtaiyaz Hassan*


DOI: 10.2174/1381612826666201125112719


Clinical Review of COVID-19; Pathogenesis, Diagnosis, and Management

, 2021; 27(41): 4232-4244.

Hussien Ahmed H. Abdelgawad*, Ahmed Sayed, Malak Munir, Mostafa H. Elberry, Ibrahim M. Sayed, Md. Amjad Kamal, Ahmed Negida, Mahmoud A. Ebada and Eshak I. Bahbah*


DOI: 10.2174/1381612826666201222162509


CA125: An Increasingly Promising Biomarker of Heart Failure

, 2021; 27(37): 3871-3880.

Chunqi Pan, Mengyun Zhou, Ying Jian, Yuanyuan Zeng, Mingwei Wang* and Feng Chen*


DOI: 10.2174/1381612827666210118122521


Polycystic Ovary Syndrome: A Contemporary Clinical Approach

, 2021; 27(36): 3812-3820.

Jelica Bjekić-Macut*, Tamara Vukašin, Zelija Velija-Ašimi, Azra Bureković, Marija Zdravković, Zoran Andrić, Marija Branković, Slobodanka Crevar-Marinović, Tatjana Madić, Olivera Stanojlović, Danijela V. Milutinović, Sarantis Livadas and George Mastorakos


DOI: 10.2174/1381612827666210119104721



Harnessing the Potential of Long Non-coding RNAs to Manage Metabolic Diseases

, 2021; 27(35): 3668-3685.

Khushdeep Bandesh , Daisy Masih , Nirjhar Bhattacharyya and Dwaipayan Bharadwaj *


DOI: 10.2174/1381612827666210315145254



Recent Updates on Current and Upcoming Biomarkers for Cardiovascular Diseases

, 2021; 27(37): 3881-3900.

Ashif Iqubal, Aamir Khan, Adeeba laeeq, Kabil Malhotra, Mohd. A. Ansari and Syed E. Haque*


DOI: 10.2174/1381612827666210224143047


Highlights on Medical Treatment of Uterine Fibroids

, 2021; 27(36): 3821-3832.

Stefano Angioni, Maurizio N. D’Alterio and Angelos Daniilidis*


DOI: 10.2174/1381612826666210101152820




Editor-in-Chief

graphic
Alessandro Antonelli
(12,288 citations)
Department of Clinical and Experimental Medicine
Laboratory of Primary Human Cells
University of Pisa
Pisa
(Italy)
Biography
View Full Editorial Board

Executive Editor

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography

Nobel Laureates on Editorial Board

graphic
Andrew V. Schally
(USA)

COPE Compliant

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Journal History

Current Pharmaceutical Design was introduced in 1995. Prof. Alessandro Antonelli serves as the Editor-in-Chief of the journal.

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