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Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

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  • 148th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

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Volume 25

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Number 15



Editorial   Open Access



Review Article

Therapeutic Effects of Hyperbaric Oxygen in the Process of Wound Healing

, 25(15): 1682 - 1693

Silvia Tejada, Juan M. Batle, Miguel D. Ferrer, Carla Busquets-Cortés, Margalida Monserrat-Mesquida, Seyed M. Nabavi, Maria del Mar Bibiloni, Antoni Pons and Antoni Sureda*


DOI: 10.2174/1381612825666190703162648


Review Article

Selenium Status in Elderly People: Longevity and Age-Related Diseases

, 25(15): 1694 - 1706

Harry Robberecht*, Tess De Bruyne, Elisabeth Davioud-Charvet, John Mackrill and Nina Hermans


DOI: 10.2174/1381612825666190701144709


Review Article

Selenium Donors at the Junction of Inflammatory Diseases

, 25(15): 1707 - 1716

Rama Alhasan, Ammar Kharma, Pierre Leroy, Claus Jacob and Caroline Gaucher*


DOI: 10.2174/1381612825666190701153903


Review Article

Chemical Aspects of Biological Activity of Isothiocyanates and Indoles, the Products of Glucosinolate Decomposition

, 25(15): 1717 - 1728

Dominik Kołodziejski, Izabela Koss-Mikołajczyk*, Ahmad Y. Abdin, Claus Jacob and Agnieszka Bartoszek


DOI: 10.2174/1381612825666190701151644


Review Article

Piperine: Old Spice and New Nutraceutical?

, 25(15): 1729 - 1739

Katarina Smilkov*, Darinka G. Ackova, Aleksandar Cvetkovski, Tatjana Ruskovska, Bojana Vidovic and Mustafa Atalay


DOI: 10.2174/1381612825666190701150803


Review Article



Review Article

Is There Something Fishy About Fish Oil?

, 25(15): 1747 - 1759

Miloš Šunderić*, Dragana Robajac, Nikola Gligorijević, Goran Miljuš, Olgica Nedić, Katarina Smilkov, Darinka Gjorgieva Ackova, Vesna Rudić-Grujić and Ana Penezić


DOI: 10.2174/1381612825666190705185800


Articles Ahead of Print





Enzyme Immobilization on Nanomaterials for Biosensor and Biocatalyst in Food and Biomedical Industry


Sundaresan Bhavaniramya*, Vanajothi Ramar, Selvaraju Vishnupriya, Kumpati Premkumar, Mohammad Saleh Al-Aboody, Rajendran Vijayakumar and Dharmar Baskaran*


DOI: 10.2174/1381612825666190712181403
View Abstract View on PubMed


The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity


Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*


DOI: 10.2174/1381612825666190619145025
View Abstract






Abstracts Ahead of Print

Colorectal Adenocarcinoma: Imaging using 5-Fluoracil Nanoparticles Labeled with Technetium 99 Metastable


Julio Cesar de Almeida, Edward Helal-Neto, Suyene Rocha Pinto, Sofia Nascimento Dos Santos, Emerson Soares Bernardes, Mohammed Al-Qahtani, Fiammetta Nigro, Luciana Magalhaes Rebelo Alencar, Eduardo Ricci-Junior and Ralph Santos-Oliveira*


DOI: 10.2174/1381612825666190816235147
View Abstract


An Updated Review on Disulfiram: Molecular Targets and Strategies for Cancer Treatment


Qingzhu Yang, Yao Yao, Kai Li, Lin Jiao, Jiazhen Zhu, Cheng Ni, Mengmeng Li, Q. Ping Dou and Huanjie Yang*


DOI: 10.2174/1381612825666190816233755
View Abstract



Published Contents

Editor's Choice


Innovative Solutions for the Control of Leishmaniases: Nanoscale Drug Delivery Systems

, 2019; 25(14): 1582 - 1592

Victoria Wagner, Aida Minguez-Menendez, Joan Pena and Christopher Fernández-Prada*


DOI: 10.2174/1381612825666190621154552





Macroalgal Polysaccharides in Biomimetic Nanodelivery Systems

, 2019; 25(11): 1265 - 1289

Nikola Geskovski, Simona Dimchevska Sazdovska and Katerina Goracinova*


DOI: 10.2174/1381612825666190423155116



Potential Regulation Mechanisms of P-gp in the Blood-Brain Barrier in Hypoxia

, 2019; 25(10): 1041 - 1051

Yidan Ding, Rong Wang*, Jianchun Zhang, Anpeng Zhao, Hui Lu, Wenbin Li, Chang Wang and Xuechun Yuan


DOI: 10.2174/1381612825666190610140153





Molecular Basis of Modulating Adenosine Receptors Activities

, 2019; 25(7): 817 - 831

Mohammed Nooraldeen Mahmod Al-Qattan* and Mohd Nizam Mordi*


DOI: 10.2174/1381612825666190304122624



The Low Molecular Weight Brain-derived Neurotrophic Factor Mimetics with Antidepressant-like Activity

, 2019; 25(6): 729 - 737

Tatiana A. Gudasheva*, Polina Povarnina, Alexey V. Tarasiuk and Sergey B. Seredenin


DOI: 10.2174/1381612825666190329122852



Open Access Articles


Effects of As2O3 and Resveratrol on the Proliferation and Apoptosis of Colon Cancer Cells and the hERG-mediated Potential Mechanisms

, 2019; 25(12): 1385 - 1391

Caichuan Yan*, Fengmei Li*, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li and Xin Zhao




The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity

, 2019; 25: 1 - 7 (E-Pub Ahead of Print)

Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*






Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*





Novel Data on the Prevalence, Identification, Scouting, and Treatment of Familial Hypercholesterolaemia

, 2018; 24(31): 3597 - 3598

Michael Doumas, Konstantinos Imprialos, Konstantinos Stavropoulos and Vasilios G. Athyros





Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

, 2018; 24(26): 3143 - 3151

Alexander N. Orekhov*, Yumiko Oishi , Nikita G. Nikiforov, Andrey V. Zhelankin, Larisa Dubrovsky, Igor A. Sobenin, Alexander Kel, Daria Stelmashenko, Vsevolod J. Makeev, Kathy Foxx, Xueting Jin, Howard S. Kruth and Michael Bukrinsky




Novel Technologies for Dipeptide Drugs Design and their Implantation

, 2018; 24(26): 3020 - 3027

Tatiana A. Gudasheva*, Rita U. Ostrovskaya and Sergey B. Seredenin




Coronary Microcirculation in Ischemic Heart Disease

, 2018; 24(25): 2893 - 2899

Axel R. Pries*, Wolfgang M. Kuebler and Helmut Habazettl




Next-generation Metabolomics in the Development of New Antidepressants: Using Albiflorin as an Example

, 2018; 24(22): 2530 - 2540

Jian Han, Yonghong Xia, Lejun Lin, Zuoguang Zhang, Hui Tian and Kefeng Li*





Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

, 2018; 24(18): 2012 - 2022

Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*





Most Cited Articles

Review Article

Rapid-acting antidepressants

, 2018; 24(22): 2556-2563.

Jeffrey M. Witkin*, Daniel E. Knutson, Gabriel J. Rodriguez and Samuel Shi


DOI: 10.2174/1381612824666180730104707


Review Article

Curcumin: A natural pan-HDAC inhibitor in cancer

, 1 January 2018; 24(2): 123-129.

Sara Saffar Soflaei, Amir Abbas Momtazi-Borojeni, Muhammed Majeed, Giuseppe Derosa, Pamela Maffioli and Amirhossein Sahebkar*


DOI: 10.2174/1381612823666171114165051


Review Article

Polyphenols: Potential use in the prevention and treatment of cardiovascular diseases

, 1 January 2018; 24(2): 239-258.

Rosaria Vincenza Giglio, Angelo Maria Patti, Arrigo F.G. Cicero, Giuseppe Lippi, Manfredi Rizzo*, Peter P. Toth and Maciej Banach


DOI: 10.2174/1381612824666180130112652


Review Article

Recent findings in molecular basis of inflammation and anti-inflammatory plants

, 2018; 24(14): 1551-1562.

Sedigheh Kazemi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei*


DOI: 10.2174/1381612824666180403122003


Review Article

Placental exosomes during gestation: Liquid biopsies carrying signals for the regulation of human parturition

, 2018; 24(9): 974-982.

Carlos Salomon*, Zarin Nuzhat, Christopher L. Dixon and Ramkumar Menon*


DOI: 10.2174/1381612824666180125164429


Review Article

Colchicine pharmacokinetics and mechanism of action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Review Article

Signaling pathways in inflammation and anti-inflammatory therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604


Review Article

Antibacterial coatings based on chitosan for pharmaceutical and biomedical applications

, 2018; 24(8): 866-885.

Juliana Miguel Vaz, Daniele Pezzoli, Pascale Chevallier, Clayton Souza Campelo, Gabriele Candiani and Diego Mantovani*


DOI: 10.2174/1381612824666180219143900



Research Article

PNitro-Tyr-PseAAC: Predict nitrotyrosine sites in proteins by incorporating five features into Chou’s general PseAAC

, 2018; 24(34): 4034-4043.

Ahmad W. Ghauri, Yaser D. Khan, Nouman Rasool, Sher A. Khan* and Kuo-Chen Chou


DOI: 10.2174/1381612825666181127101039



Review Article

Curcumin as an adjunct therapy and microRNA modulator in breast cancer

, 1 January 2018; 24(2): 171-177.

Saeed Norouzi, Muhammed Majeed, Matteo Pirro, Daniele Generali and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666171129203506



Review Article

The role of formyl peptide receptors for immunomodulatory activities of antimicrobial peptides and peptidomimetics

, 2018; 24(10): 1100-1120.

Sarah Line Skovbakke*, Andre Holdfeldt, Huamei Forsman, Johan Bylund and Henrik Franzyk*


DOI: 10.2174/1381612824666180403123233


Research Article

Virtual screening and statistical analysis in the design of new caffeine analogues molecules with potential epithelial anticancer activity

, 2018; 24(5): 576-594.

Josivan da Silva Costa*, Karina da Silva Lopes Costa, Josiane Viana Cruz, Ryan da Silva Ramos, Luciane Barros Silva, Davi Do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos and Williams Jorge da Cruz Macedo


DOI: 10.2174/1381612823666170711112510



Most Accessed Articles

Advances in Binding Free Energies Calculations: QM/MM-Based Free Energy Perturbation Method for Drug Design

, 2013; 19(26): 4674-4686.

R.S. Rathore, M. Sumakanth, M. Siva Reddy, P. Reddanna, Allam Appa Rao, Mark D. Erion and M.R. Reddy


DOI: 10.2174/1381612811319260002


Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847


JAK Inhibition: The Most Promising Agents in the IBD Pipeline?

, 2019; 25(1): 32-40.

Agnès Fernández-Clotet, Jesús Castro-Poceiro and Julián Panés*


DOI: 10.2174/1381612825666190405141410


Reversal of Novel Anticoagulants in Emergent Surgery and Trauma: A Comprehensive Review and Proposed Management Algorithm

, 2018; 24(38): 4540-4553.

Leonidas Palaiodimos*, Jeremy Miles, Damianos G. Kokkinidis, Christos Barkolias, Anil K. Jonnalagadda, Dimitrios Papaconstantinou, Maximos Frountzas, Evangelos P. Misiakos and Dimitrios Schizas


DOI: 10.2174/1381612825666181226150629


Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins

, 2018; 24(41): 4932-4946.

Huanbo Tan, Wencheng Su, Wenyu Zhang, Pengju Wang, Michael Sattler and Peijian Zou*


DOI: 10.2174/1381612825666190206105232




Computer-aided Drug Design and Drug Pharmacokinetic Prediction: A Mini-review

, 2018; 24(26): 3014-3019.

Jamshid Tabeshpour, Amirhossein Sahebkar*, Mohammad Reza Zirak, Majid Zeinali, Mahmoud Hashemzaei, Sajed Rakhshani and Saleh Rakhshani*


DOI: 10.2174/1381612824666180903123423


Mineralocorticoid Receptor Antagonists for Nephroprotection: Current Evidence and Future Perspectives

, 2018; 24(46): 5528-5536.

Pantelis A. Sarafidis*, Evangelos Memmos, Maria-Eleni Alexandrou and Aikaterini Papagianni


DOI: 10.2174/1381612825666190306162658




Editor-in-Chief

William A. Banks
(29546 citations)
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
USA

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
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Scopus CiteScore Metrics: 1.15

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