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Current Pharmaceutical Biotechnology

Volume 21, 15 Issues, 2020
ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth/mini reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:

  • DNA/protein engineering and processing
  • Synthetic biotechnology
  • Omics (genomics, proteomics, metabolomics and systems biology)
  • Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
  • Drug delivery and targeting
  • Nanobiotechnology
  • Molecular pharmaceutics and molecular pharmacology
  • Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
  • Pharmacokinetics and pharmacodynamics
  • Applied Microbiology
  • Bioinformatics (computational biopharmaceutics and modeling)
  • Environmental biotechnology
  • Regenerative medicine (stem cells, tissue engineering and biomaterials)
  • Translational immunology (cell therapies, antibody engineering, xenotransplantation)
  • Industrial bioprocesses for drug production and development
  • Biosafety
  • Biotech ethics

Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.

Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Current Pharmaceutical Biotechnology

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Volume 21

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Number 11



Biography   Open Access



Review Article

Curcumin Therapeutic Modulation of the Wnt Signaling Pathway

, 21(11): 1006 - 1015

Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi*, Maria-Corina Serban , Hossein M. Orafai and Amirhossein Sahebkar*


DOI: 10.2174/1389201021666200305115101


Review Article



Review Article



Systematic Review Article

A Systematic Review and Meta-Analysis: The Effectiveness of Probiotics for Viral Gastroenteritis

, 21(11): 1042 - 1051

Fereshteh Ansari, Fariba Pashazadeh, Elaheh Nourollahi, Sakineh Hajebrahimi, Zachary Munn and Hadi Pourjafar*


DOI: 10.2174/1389201021666200416123931


Letter Article

Should the Vancomycin Minimal Inhibitory Concentration be used as an Infant Critical Care Regular Criteria?

, 21(11): 1052 - 1058

Nadielle S. Bidu, Bruno J.D. Fernandes, Jucelino N.C. Filho, Regina E.A. Bastos, Joice N.R. Pedreira and Ricardo D. Couto*


DOI: 10.2174/1389201021666200327162402


Research Article



Research Article



Current Pharmaceutical Biotechnology, Volume 21 (2020) - Number 12


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print







Novel Therapeutic Approaches and Treatment Targets for Psoriatic Arthritis


Devis Benfaremo, Valentino Paci, Michele Maria Luchetti* and Armando Gabrielli


DOI: 10.2174/1389201021666200928095521
View Abstract


Phytochemistry, Traditional Uses and Pharmacological properties of Enhydra fluctuans Lour: A Comprehensive Review.


Antica Barua, Muhammad Shaiful Alam, Md. Junaid, Yeasmin Akter, Syeda Samira Afrose, Tania Sharmin*, Rasheda Akter and S. M. Zahid Hosen


DOI: 10.2174/1389201021666200922161529
View Abstract


Investigation on the Antibacterial Activity of Electronic Cigarette Liquids (ECLs): A Proof of Concept Study


Virginia Fuochi, Massimo Caruso , Rosalia Emma, Aldo Stivala, Riccardo Polosa, Alfio Distefano and Pio Maria Furneri *


DOI: 10.2174/1389201021666200903121624
View Abstract View on PubMed


Recent Advances in the Scaffold Engineering of Protein Binders


Mohammad Karimi Baba Ahmadi, Seyed Abolgasem Mohammadi, Manoochehr Makvandi, Morteza Mamouei, Mohammad Rahmati*, Hesam Dehghani and David W. Wood


DOI: 10.2174/1389201021999200824101035
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Editor's Choice

Curcumin Therapeutic Modulation of the Wnt Signaling Pathway

, 2020; 21(11): 1006 - 1015

Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi*, Maria-Corina Serban , Hossein M. Orafai and Amirhossein Sahebkar*


DOI: 10.2174/1389201021666200305115101



Current Prospects of Nutraceuticals: A Review

, 2020; 21(10): 884 - 896

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441




The Physiologic Activity and Mechanism of Quercetin-Like Natural Plant Flavonoids

, 2020; 21(8): 654 - 658

Wujun Chen, Shuai Wang, Yudong Wu, Xin Shen, Shutan Xu, Zhu Guo*, Renshuai Zhang* and Dongming Xing*


DOI: 10.2174/1389201021666200212093130




Feasibility Study for Bedside Production of Recombinant Human Acid α-Glucosidase: Technical and Financial Considerations

, 2020; 21(6): 467 - 479

Mohammed H. Aldosari*, Marcel den Hartog, Hubertina Ganizada, Martijn J.W. Evers, Enrico Mastrobattista and Huub Schellekens


DOI: 10.2174/1389201021666200217113049



Active Targeting Towards and Inside the Brain based on Nanoparticles: A Review

, 2020; 21(5): 374 - 383

Morteza Rabiei, Soheila Kashanian*, Seyedeh S. Samavati, Shahriar Jamasb and Steven J.P. McInnes


DOI: 10.2174/1389201020666191203094057






Open Access Articles

Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line

, 2020; 21(12): 1269 - 1277

Kamil Kiełbasiński*, Wojciech Peszek, Beniamin Oskar Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska and Marcin Oplawski





Differences in the Expression Pattern of mRNA Protein SEMA3F in Endometrial Cancer in vitro under Cisplatin Treatment

, 2020; 21(11): 1119 - 1128

Przemysław Kieszkowski*, Dariusz Dąbruś, Beniamin O. Grabarek and Dariusz Boroń




Analysis of the Clinical Diagnostic Value of GMFB in Cerebral Infarction

, 2020; 21(10): 955 - 963

Zhaohu Yuan*, Zhiwu Yu, Yiyu Zhang and Huikuan Yang




Plant Phenolics as Pathogen-Carrier Immunogenicity Modulator Haptens

, 2020; 21(10): 897 - 905

Castillo-Maldonado Irais, Sevilla-González María-de-la-Luz, Delgadillo-Guzmán Dealmy, Ramírez-Moreno Agustina, Cabral-Hipólito Nidia, Rivera-Guillén Mario-Alberto, Serrano-Gallardo Luis-Benjamín*, Vega-Menchaca María-del-Carmen and Pedroza-Escobar David*





The Anti-Inflammatory Effects of Anacardic Acid on a TNF-α - Induced Human Saphenous Vein Endothelial Cell Culture Model

, 2020; 21(8): 710 - 719

Burak Önal*, Deniz Özen, Bülent Demir, Duygu Gezen Ak, Erdinç Dursun, Caner Demir, Ahmet Gökhan Akkan and Sibel Özyazgan




Development of Formulation Methods and Physical Characterization of Injectable Sodium Selenite Nanoparticles for the Delivery of Sorafenib tosylate

, 2020; 21(8): 659 - 666

Sivakumar S. Moni*, Mohammad F. Alam*, Mohammed M. Safhi , Muhammad H. Sultan, Hafiz A. Makeen and Mohamed E. Elmobark




Assessment of Expression of Homeobox A5 in Endometrial Cancer on the mRNA and Protein Level

, 2020; 21(7): 635 - 641

Konrad Dziobek*, Marcin Oplawski, Nikola Zmarzły, Beniamin O. Gabarek, Robert Kiełbasiński, Kamil Kiełbasiński, Przemysław Kieszkowski, Karol Talkowski and Dariusz Boroń




Relationship between SNP rs1764391 and Susceptibility, Risk Factors, Gene-environment Interactions of Acute Myocardial Infarction in Guangxi Han Chinese Population

, 2020; 21(1): 79 - 88

Jun Li, Rui Qin, Wei Wang*, Zhou Huang, Dong-Ling Huang, Tian Li, Fan Wang, Xiang-tao Zeng, Zhong-yi Sun, Xue-feng Liu, Feng Huang and Tao Guo




Variances in the Level of COX-2 and iNOS in Different Grades of Endometrial Cancer

, 2020; 21(1): 52 - 59

Marcin Oplawski*, Konrad Dziobek, Nikola Zmarzły, Beniamin O. Grabarek, Robert Kiełbasiński, Przemysław Kieszkowski, Piotr Januszyk, Karol Talkowski, Michał Schweizer, Piotr Kras, Andrzej Plewka and Dariusz Boroń




The Influence of Salinomycin on the Expression Profile of mRNAs Encoding Selected Caspases and MiRNAs Regulating their Expression in Endometrial Cancer Cell Line

, 2020; 21: 1 - 11 (E-Pub Ahead of Print)

Krzysztof Januszyk*, Piotr Januszyk, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski




Salinomycin Modulates the Expression of mRNAs and miRNAs Related to Stemness in Endometrial Cancer

, 2020; 21: 1 - 10 (E-Pub Ahead of Print)

Karol Talkowski*, Kamil Kiełbasiński, Wojciech Peszek, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski




Analysis of the Differences in the Expression of mRNAs and miRNAs Associated with Drug Resistance in Endometrial Cancer Cells Treated with Salinomycin

, 2020; 21: 1 - 8 (E-Pub Ahead of Print)

Piotr Januszyk*, Krzysztof Januszyk, Magdalena Wierzbik-Strońska, Dariusz Boroń and Beniamin Grabarek




Evaluation of Variances in VEGF-A-D and VEGFR-1-3 Expression in the Ishikawa Endometrial Cancer Cell Line Treated with Salinomycin and Anti-Angiogenic/Lymphangiogenic Effect

, 2020; 21: 1 - 9 (E-Pub Ahead of Print)

Piotr Kras*, Karol Talkowski, Beniamin Oskar Grabarek, Nina Dziobek, Dariusz Boroń and Marcin Oplawski





Most Cited Articles


Research Article

Healthcare-associated infections due to multidrug-resistant organisms: A surveillance study on extra hospital stay and direct costs

, 2019; 20(8): 643-652.

Guglielmo Giraldi, Marzietta Montesano, Christian Napoli, Paola Frati, Raffaele La Russa, Alessandro Santurro, Matteo Scopetti and Giovanni B. Orsi*


DOI: 10.2174/1389201020666190408095811


Review Article

Functional biomolecule delivery systems and bioengineering in cartilage regeneration

, 2019; 20(1): 32-46.

Marta A. Szychlinska, Ugo D'Amora, Silvia Ravalli, Luigi Ambrosio, Michelino Di Rosa and Giuseppe Musumeci*


DOI: 10.2174/1389201020666190206202048


Research Article

New rules on patient’s safety and professional liability for the Italian health service

, 2019; 20(8): 615-624.

Sara Albolino, Tommaso Bellandi, Simone Cappelletti, Marco Di Paolo, Vittorio Fineschi*, Paola Frati, Caterina Offidani, Michela Tanzini, Riccardo Tartaglia and Emanuela Turillazzi


DOI: 10.2174/1389201020666190408094016


Research Article

Effect of pullulan on physicochemical, microbiological, and sensory quality of yogurts

, 2019; 20(6): 489-496.

Anna Chlebowska-Śmigiel, Katarzyna Kycia, Katarzyna Neffe-Skocińska, Marek Kieliszek*, Małgorzata Gniewosz and Danuta Kołożyn-Krajewska


DOI: 10.2174/1389201020666190416151129


Review Article

Recent insights into effective nanomaterials and biomacromolecules conjugation in advanced drug targeting

, 2019; 20(7): 526-541.

Abbas H. Azandaryani , Soheila Kashanian * and Tahereh Jamshidnejad-Tosaramandani


DOI: 10.2174/1389201020666190417125101




Review Article

Ginger: A novel strategy to battle cancer through modulating cell signalling pathways: A review

, 2019; 20(1): 5-16.

Ahmad Almatroudi, Mohammed A. Alsahli, Faris Alrumaihi, Khaled S. Allemailem and Arshad H. Rahmani*


DOI: 10.2174/1389201020666190119142331



Review Article

Antibiotics application strategies to control biofilm formation in pathogenic bacteria

, 2020; 21(4): 270-286.

Fazlurrahman Khan, Dung T.N. Pham, Sandra F. Oloketuyi and Young-Mog Kim*


DOI: 10.2174/1389201020666191112155905



Review Article

Current prospects of nutraceuticals: A review

, 2020; 21(10): 884-896.

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441



Research Article

Changes in the expression profile of VEGF-A, VEGF-B, VEGFR-1, VEGFR-2 in different grades of endometrial cancer

, 2019; 20(11): 955-963.

Konrad Dziobek*, Marcin Opławski, Beniamin Oskar Grabarek, Nikola Zmarzły, Barbara Tomala, Tomasz Halski, Ewa Leśniak, Krzysztof Januszyk, Ryszard Brus, Robert Kiełbasiński and Dariusz Boroń


DOI: 10.2174/1389201020666190717092448



Most Accessed Articles


CAR T-cell Therapy: A New Era in Cancer Immunotherapy

, 2018; 19(1): 5-18.

Androulla N. Miliotou and Lefkothea C. Papadopoulou*


DOI: 10.2174/1389201019666180418095526




Laser Assisted Cell Printing

, 2013; 14(1): 91-97.

L. Koch, M. Gruene, C. Unger and B. Chichkov


DOI: 10.2174/1389201011314010012



DAB389EGF Fusion Protein Therapy of Refractory Glioblastoma Multiforme

, 2003; 4(1): 39-49.

Kimberley A. Cohen, TieFu Liu, Reid Bissonette, Raj K. Puri and Arthur E. Frankel


DOI: 10.2174/1389201033378039


Reversing Breast Cancer Stem Cell into Breast Somatic Stem Cell

, 2011; 12(2): 189-195.

L. Wijaya, D. Agustina, A. O. Lizandi, M. M. Kartawinata and F. Sandra


DOI: 10.2174/138920111794295819


Therapeutic Gene Products Delivery by Neuron Stem Cells

, 2012; 13(12): 2427-2431.

Jie Tan, Yanna Meng, Shiang Huang and Ping Wang


DOI: 10.2174/138920112803341806



Editor-in-Chief

Nikolaos Labrou
Department of Biotechnology
Agricultural University of Athens
Athens
(Greece)
Biography
View Full Editorial Board

COPE Compliant

Journal History

Current Pharmaceutical Biotechnology was launched in 2000. Dr. Nikolaos Labrou serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.97

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