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Current Proteomics

Volume 16, 5 Issues, 2019
ISSN: 1875-6247 (Online)
ISSN: 1570-1646 (Print)
This journal supports open access

Aims & Scope

Research in the emerging field of proteomics is growing at an extremely rapid rate. The principal aim of Current Proteomics is to publish well-timed in-depth/mini review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry.

Current Proteomics publishes in-depth/mini review articles in all aspects of the fast-expanding field of proteomics. All areas of proteomics are covered together with the methodology, software, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to:

  • Protein separation and characterization techniques
  • 2-D gel electrophoresis and image analysis
  • Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching
  • Determination of co-translational and post- translational modification of proteins
  • Protein/peptide microarrays
  • Biomolecular interaction analysis
  • Analysis of protein complexes
  • Yeast two-hybrid projects
  • Protein-protein interaction (protein interactome) pathways and cell signaling networks
  • Systems biology
  • Proteome informatics (bioinformatics)
  • Knowledge integration and management tools
  • High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography)
  • High-throughput computational methods for protein 3-D structure as well as function determination
  • Robotics, nanotechnology, and microfluidics

In addition to in-depth reviews, articles highlighting recent proteomics papers of special interest as well as book reviews are published. Mini-reviews and perspective articles are also published. In view of the importance of specific technology and software developed for advancement of proteomics research, a separate section is devoted to product and technology reports. Proceedings of proteomics meetings with selected review articles on topics presented are also published.

Current Proteomics

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Volume 16

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Number 3



Biography   Open Access



Research Article



Research Article



Research Article

Proteomic Analysis of a Bioactive Aloe vera Extract

, 16(3): 181 - 187

Ethel Daniela Cabello-Ruiz, Víctor Manuel Torres-de la Cruz*, Catalina Rivas-Morales, Gloria María Molina-Salinas, María Adriana Núñez-González, María Julia Verde-Star and Catalina Leos-Rivas


DOI: 10.2174/1570164615666180925150839


Research Article

Assessment of Signal Peptides to Optimize Interleukin 2 (IL-2) Folding and Expression

, 16(3): 188 - 198

Narges Nazifi, Mojtaba Tahmoorespur*, Mohammad Hadi Sekhavati*, Alireza Haghparast and Mohammad Ali Behroozikhah


DOI: 10.2174/1570164615666181024113612


Research Article

Effect of Intestinal Flora Clearance on Liver Proteomics in Mice

, 16(3): 199 - 209

Zhenghu Jia, Hui Liu, Mei Song, Chengmao Yang, Yapu Zhao, Xiaoli Wu, Zhenzhou Wu and Liqing Zhao*


DOI: 10.2174/1570164616666181115102046


Research Article



Research Article



Current Proteomics, Volume 16 (2019) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Identifying Ligand-receptor Interactions via an Integrated Fuzzy Model


Chang Xu, Limin Jiang, Yi Jie Ding, Cong Shen, Gaoyan Zhang* and Xuyao Yu*


View Abstract


An Integrated Prediction Method for Identifying Protein-Protein Interactions


Chang Xu, Limin Jiang, Zehua Zhang, Xuyao Yu, Renhai Chen* and Junhai Xu*


View Abstract


In silico Evaluation of Substrate Binding Site and Rare Codons in the Structure of CYP152A1


Mojtaba Mortazavi, Navid Nezafat, Manica Negahdaripour, Mohammad J. Raee, Masoud Torkzadeh-Mahani, Ali Riahi-Madvar and Younes Ghasemi*


View Abstract


Analysis of Extracellular Proteome of Staphylococcus aureus: A Mass Spectrometry based Proteomics Method of Exotoxin Characterisation


Rajdeep Das, Nisha D`souza, Surya Kant Choubey, Sethumadhavan Murlidharan, Anura V. Kurpad and Amit Kumar Mandal*


View Abstract


Identification of Novel Breast Cancer Genes based on Gene Expression Profiles and PPI Data


Cheng-Wen Yang, Huan-Huan Cao, Yu Guo, Yuan-Ming Feng and Ning Zhang*


View Abstract



Protein Subcellular Localization Prediction based on PSI-BLAST Profile and Principal Component Analysis


Yuhua Yao*, Manzhi Li , Huimin Xu, Shoujiang Yan, Ping-an He, Qi Dai, Zhaohui Qi and Bo Liao


View Abstract


Role of Cervical Cancer Radiotherapy in the Expression of EGFR and p53 Gene


Yan Cheng, Kuntian Lan, Xiaoxia Yang, Dongxia Liang, Li Xia and Jinquan Cui*


View Abstract




Abstracts Ahead of Print

Evaluation of luciferase thermal stability by arginine saturation in the flexible loops


Farzane Kargar, Mojtaba Mortazavi*, Masoud Torkzadeh-Mahani, Safa Lotfi and Shahryar Shakeri


View Abstract


Editor's Choice

Assessment of Signal Peptides to Optimize Interleukin 2 (IL-2) Folding and Expression

, 2019; 16(3): 188 - 198

Narges Nazifi, Mojtaba Tahmoorespur*, Mohammad Hadi Sekhavati*, Alireza Haghparast and Mohammad Ali Behroozikhah


DOI: 10.2174/1570164615666181024113612



Proteomic Analysis of Cerebrospinal Fluid: A Search for Biomarkers of Neuropsychiatric Systemic Lupus Erythematosus

, 2019; 16(2): 110 - 118

Johanna Pedroza-Díaz*, Tania Paola Luján Chavarria, Carlos Horacio Muñoz Vahos, Diego Francisco Hernández Ramírez, Elizabeth Olivares-Martínez, Gloria Vásquez, Luis Llorente, Hilda Fragoso-Loyo, Sarah Röthlisberger and Blanca Lucía Ortiz Reyes


DOI: 10.2174/1570164615666180911125252





SELDI-TOF-MS Profiling of Metastatic Phenotype in Histopathological Subtypes of Breast Cancer

, 2018; 15(3): 214 - 220

Turkan Yigitbasi*, Gizem Calibasi-Kocal, Nihal Buyukuslu, Murat Kemal Atahan, Hakan Kupeli, Seyran Yigit, Ercument Tarcan and Yasemin Baskin


DOI: 10.2174/1570164615666180309154038






Proteomic Analysis of the Kidney in Rat Biliary Cirrhosis

, 2017; 14(3): 234 - 241

Noemí M. Atucha, Paola Romecin, Francisco Solano and Joaquín García-Estañ*


DOI: 10.2174/1570164614666170206130033




Open Access Articles



B-factor Analysis and Conformational Rearrangement of Aldose Reductase

, 2014; 11(3): 151 - 160

Ganesaratnam K. Balendiran, J. Rajendran Pandian, Evin Drake, Anubhav Vinayak, Malkhey Verma and Duilio Cascio




Important Anti-Cancer Applications of Protein Based Nanoparticles

, 2013; 10(4): 334 - 340

Mustafa Ergul, Merve Ergul and Yusuf Tutar*




A Simple Protein Extraction Method for Proteomic Analysis of Diverse Biological Specimens

, 2013; 10(4): 298 - 311

Panga Jaipal Reddy, Aishwarya Anand Rao, Darpan Malhotra, Samridhi Sharma, Ravinder Kumar, Rekha Jain, Kishore Gollapalli, Namita Pendharkar, Srikanth Rapole and Sanjeeva Srivastava




Anti-cancer Therapies in High Grade Gliomas

, 2013; 10(3): 246 - 260

Cristiana Pistol Tanase, Ana-Maria Enciu, Simona Mihai, Ana Iulia Neagu, Bogdan Calenic and Maria Linda Cruceru




Protein Biomarkers in Cancers of the Digestive Tract - a Step Towards Personalized Medicine

, 2013; 10(3): 228 - 236

Erno Duda, Elena Codrici, Daniela Ionela Popescu, Laura Necula and Radu Albulescu





Neuro-endocrine Markers in Neoplasms. Diagnostic Interest and Future Prospects

, 2013; 10(3): 194 - 201

Gianni Bussolati, Carmen Ardeleanu and Maria Comanescu




Protein Arrays: Recent Achievements and their Application to Study the Human Proteome

, 2013; 10(2): 83 - 97

Juan Casado-Vela, Maria Gonzalez-Gonzalez, Sergio Matarraz, Maria Jose Martinez-Esteso, Maite Vilella, Jose Maria Sayagues, Manuel Fuentes and Juan Carlos Lacal




MALDI Imaging Mass Spectrometry – A Novel Approach in Biomedical Research of Tissues

, 2013; 10(2): 76 - 82

Magdalena Kalinowska-Herok, Monika Pietrowska, Anna Walaszczyk and Piotr Wid ak




A Quantitative Proteomics Approach in the Study of MicroRNA 181a in HepG2 Cells

, 2012; 9(4): 262 - 271

Yi Lin Jane Tan, Nagy A. Habib and Wei Ning Chen




Silicon: A Multitalented Micronutrient in OMICS Perspective – An Update

, 2012; 9(4): 245 - 254

Sajad Majeed Zargar, Muzafar Ahmad Macha, Muslima Nazir, Ganesh Kumar Agrawal and Randeep Rakwal




Proteomic Analysis of Phosphorylation in the Brain

, 2012; 9(3): 167 - 185

Ry Y. Tweedie-Cullen, Andrea M. Brunner and Isabelle M. Mansuy




Computational Methods and Algorithms for Mass Spectrometry Based Differential Proteomics: Recent Advances, Perspectives and Open Problems

, 2012; 9(3): 143 - 159

Vasiliki Spyropoulou, Maria Anna Rapsomaniki, Konstantinos Theofilatos, Stergios Papadimitriou, Spiros Likothanassis, Athanasios Tsakalidis and Seferina Mavroudi





Most Cited Articles


In Silico Study of Different Signal Peptides for Secretory Production of Interleukin-11 in Escherichia coli

, 2017; 14(2): 112-121.

Manica Negahdaripour, Navid Nezafat, Nasim Hajighahramani, Seyyed Soheil Rahmatabadi, Mohammad Hossein Morowvat and Younes Ghasemi*


DOI: 10.2174/1570164614666170106110848


Prediction of MicroRNA–disease Associations by Matrix Completion

, 2016; 13(2): 151-157.

Xiangxiang Zeng, Ningxiang Ding, Alfonso Rodríguez-Patón, Ziyu Lin and Ying Ju*


DOI: 10.2174/157016461302160514005711





In silico Investigation of Pullulanase Enzymes from Various Bacillus Species

, 2017; 14(3): 175-185.

Seyyed Soheil Rahmatabadi, Issa Sadeghian, Navid Nezafat, Manica Negahdaripour, Nasim Hajighahramani, Shiva Hemmati and Younes Ghasemi*


DOI: 10.2174/1570164614666170306164830


The Quest for Novel Biomarkers in Early Diagnosis of Diabetic Neuropathy

, 2017; 14(2): 86-99.

Mihaela Adriana Ghita, Constantin Caruntu*, Daniela Lixandru, Adriana Pitea, Alexandra Batani and Daniel Boda


DOI: 10.2174/1570164614666161228122259


Effects of Acute and Chronic Biomechanical Strain on Human Cerebral Endothelial Cells in Altering their Proteome Profile

, 2017; 14(3): 214-223.

Nurul Farhana Jufri, Abidali Mohamedali, Seong Beom Ahn, Alberto Avolio and Mark Scott Baker*


DOI: 10.2174/1570164614666170213141932


Novel Potent Plasmepsin-I (PMI) Inhibitors: An In-Silico Approach

, 2016; 13(3): 196-205.

Kamal Kumar Chaudhary, Utkarsh Raj, Pritish Kumar Varadwaj and Nidhi Mishra


DOI: 10.2174/1570164613666160722101951




Most Accessed Articles




Designing of Artificial Peptides for an Improved Antiviral Activity

, 2018; 15(4): 258-266.

Speranta Avram, Adina-Luminita Milac, Livia-Cristina Borcan, Dan Mihailescu, Florin Borcan* and Miguel Castanho


DOI: 10.2174/1570164615666180409151111






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