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Current Gene Therapy

Volume 19, 6 Issues, 2019
ISSN: 1566-5232 (Print)
ISSN: 1875-5631 (Online)
This journal supports open access

Ranking and Category

  • 108th of 174 in

    Genetics & Heredity

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Aims & Scope

Current Gene Therapy is a bi-monthly peer-reviewed journal aimed at academic and industrial scientists with an interest in major topics concerning basic research and clinical applications of gene and cell therapy of diseases. Cell therapy manuscripts can also include application in diseases when cells have been genetically modified. Current Gene Therapy publishes full-length/mini reviews and original research on the latest developments in gene transfer and gene expression analysis, vector development, cellular genetic engineering, animal models and human clinical applications of gene and cell therapy for the treatment of diseases.

Current Gene Therapy publishes reviews and original research containing experimental data on gene and cell therapy. The journal also includes manuscripts on technological advances, ethical and regulatory considerations of gene and cell therapy. Reviews should provide the reader with a comprehensive assessment of any area of experimental biology applied to molecular medicine that is not only of significance within a particular field of gene therapy and cell therapy but also of interest to investigators in other fields. Authors are encouraged to provide their own assessment and vision for future advances. Reviews are also welcome on late breaking discoveries on which substantial literature has not yet been amassed. Such reviews provide a forum for sharply focused topics of recent experimental investigations in gene therapy primarily to make these results accessible to both clinical and basic researchers. Manuscripts containing experimental data should be original data, not previously published.

Current Gene Therapy

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Volume 19

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Number 4



Biography   Open Access



Editorial   Open Access



Research Article



Research Article



Research Article



Research Article



Research Article

A Recurrent Rare SOX9 Variant (M469V) is Associated with Congenital Vertebral Malformations

, 19(4): 242 - 247

Nan Wu, Lianlei Wang, Jianhua Hu*, Sen Zhao, Bowen Liu, Yaqi Li, Huakang Du, Yuanqiang Zhang, Xiaoxin Li, Zihui Yan, Shengru Wang, Yipeng Wang, Jianguo Zhang, Zhihong Wu, DISCO (Deciphering Disorders Involving Scoliosis & Comorbidities) study group and Guixing Qiu


DOI: 10.2174/1566523219666190924120307


General Review Article

Partial Reprogramming As An Emerging Strategy for Safe Induced Cell Generation and Rejuvenation

, 19(4): 248 - 254

Marianne Lehmann, Martina Canatelli-Mallat, Priscila Chiavellini, Gloria M. Cónsole, Maria D. Gallardo and Rodolfo G. Goya*


DOI: 10.2174/1566523219666190902154511


Current Gene Therapy, Volume 19 (2019) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

There are currently no Articles Ahead of Print available for this journal.

Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Partial Reprogramming As An Emerging Strategy for Safe Induced Cell Generation and Rejuvenation

, 2019; 19(4): 248 - 254

Marianne Lehmann, Martina Canatelli-Mallat, Priscila Chiavellini, Gloria M. Cónsole, Maria D. Gallardo and Rodolfo G. Goya*


DOI: 10.2174/1566523219666190902154511



Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy

, 2019; 19(3): 197 - 207

Angela L. McCall*, Sylvia G. Stankov, Gabrielle Cowen, Denise Cloutier, Zizhao Zhang, Lin Yang, Nathalie Clement, Darin J. Falk and Barry J. Byrne*


DOI: 10.2174/1566523219666190621113807





Neuroprotection by Human Dental Pulp Mesenchymal Stem Cells: From Billions to Nano

, 2018; 18(5): 307 - 323

Chaitra Venugopal, Shobha K, Kiranmai S. Rai, Venkata Bharatkumar Pinnelli, Bindu M. Kutty and Anandh Dhanushkodi*


DOI: 10.2174/1566523218666180913152615




Gene Therapy to Enhance Bone and Cartilage Repair in Orthopaedic Surgery

, 2018; 18(3): 154 - 170

Sofia Bougioukli, Christopher H. Evans, Ram K. Alluri, Steven C. Ghivizzani and Jay R. Lieberman*


DOI: 10.2174/1566523218666180410152842






Open Access Articles

Hemophilia Gene Therapy: New Development from Bench to Bed Side

, 2019; 19(4): 264 - 273

Xiao-Lu Guo, Tsai-Hua Chung, Yue Qin, Jie Zheng, Huyong Zheng, Liyuan Sheng, Tung Wynn and Lung-Ji Chang*




Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy

, 2019; 19(3): 197 - 207

Angela L. McCall*, Sylvia G. Stankov, Gabrielle Cowen, Denise Cloutier, Zizhao Zhang, Lin Yang, Nathalie Clement, Darin J. Falk and Barry J. Byrne*




Three Cases of Leber’s Hereditary Optic Neuropathy with Rapid Increase in Visual Acuity After Gene Therapy

, 2019; 19(2): 134 - 138

Yong Zhang, Jia-jia Yuan, Hong-li Liu, Zhen Tian, Si-wei Liu and Bin Li*





Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2019; 19(1): 40 - 53

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*





Clinical Observation of Patients with Leber’s Hereditary Optic Neuropathy Before Gene Therapy

, 2018; 18(6): 386 - 392

Jiajia Yuan, Yong Zhang, Hongli Liu, Zhen Tian, Xin Li, Yichen Zheng, Qin Gao, Lin Song, Xiao Xiao, Jian Sun, Zhitao Wang and Bin Li*




Clinical-Grade Oncolytic Adenovirus Purification Using Polysorbate 20 as an Alternative for Cell Lysis

, 2018; 18(6): 366 - 374

Mafalda G. Moleirinho, Sara Rosa, Manuel J.T. Carrondo*, Ricardo J.S. Silva, Åsa Hagner-McWhirter, Gustaf Ahlén, Mats Lundgren, Paula M. Alves and Cristina Peixoto




Emerging Therapeutic Approaches for Diamond Blackfan Anemia

, 2018; 18(6): 327 - 335

Anna Aspesi*, Chiara Borsotti and Antonia Follenzi*




EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275 - 285

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*




Human Disease System Biology

, 2018; 18(5): 255 - 256

Liang Cheng and Yang Hu




Oncolytic Virotherapy for Breast Cancer Treatment

, 2018; 18(4): 192 - 205

Samia M. O`Bryan and J. Michael Mathis*




Genetics and Therapies for GM2 Gangliosidosis

, 2018; 18(2): 68 - 89

Maria Begona Cachon-Gonzalez*, Eva Zaccariotto and Timothy Martin Cox





Molecular Adjuvants Based on Plasmids Encoding Protein Aggregation Domains Affect Bone Marrow Niche Homeostasis

, 2017; 17(5): 391 - 397

Maria Giovanna Sabbieti, Giovanna Lacava, Andrea Amaroli, Luigi Marchetti, Roberta Censi, Piera Di Martino and Dimitrios Agas*





Most Cited Articles

General Review Article

Circular RNAs serve as novel biomarkers and therapeutic targets in cancers

, 2019; 19(2): 125-133.

Shuai Fang, Jinchang Pan, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaofeng Jin, Xiaodan Meng, Nan Jiang and Zhaohui Gong*


DOI: 10.2174/1566523218666181109142756


Editorial

Human Disease System Biology

, 2018; 18(5): 255-256.

Liang Cheng and Yang Hu


DOI: 10.2174/1566523218666181010101114



Review Article

Mir-7 replacement therapy in parkinson’s disease

, 2018; 18(3): 143-153.

Ricardo Titze-de-Almeida* and Simoneide Souza Titze-de-Almeida*


DOI: 10.2174/1566523218666180430121323


Research Article

Transplantation of BDNF gene recombinant mesenchymal stem cells and adhesive peptide-modified hydrogel scaffold for spinal cord repair

, 2018; 18(1): 29-39.

Li-Ming Li, Ling-Ling Huang, Xin-Chi Jiang, Jia-Chen Chen, Hong-Wei OuYang and Jian-Qing Gao *


DOI: 10.2174/1566523218666180413150023


Review Article

Gene therapy to enhance bone and cartilage repair in orthopaedic surgery

, 2018; 18(3): 154-170.

Sofia Bougioukli, Christopher H. Evans, Ram K. Alluri, Steven C. Ghivizzani and Jay R. Lieberman*


DOI: 10.2174/1566523218666180410152842


Review Article

Genetics and therapies for GM2 gangliosidosis

, 2018; 18(2): 68-89.

Maria Begona Cachon-Gonzalez*, Eva Zaccariotto and Timothy Martin Cox


DOI: 10.2174/1566523218666180404162622


Review Article

A Brief Survey of Machine Learning Application in Cancerlectin Identification

, 2018; 18(5): 257-267.

Hong-Yan Lai, Chao-Qin Feng, Zhao-Yue Zhang, Hua Tang, Wei Chen* and Hao Lin*


DOI: 10.2174/1566523218666180913112751


Review Article

Nonviral delivery systems for cancer gene therapy: Strategies and challenges

, 2018; 18(1): 3-20.

Gayong Shim*, Dongyoon Kim, Quoc-Viet Le, Gyu Thae Park, Taekhyun Kwon and Yu-Kyoung Oh*


DOI: 10.2174/1566523218666180119121949


Review Article

Genetics and gene therapy of anderson-fabry disease

, 2018; 18(2): 96-106.

Irene Simonetta*, Antonino Tuttolomondo, Tiziana Di Chiara, Salvatore Miceli, Danai Vogiatzis, Francesca Corpora and Antonio Pinto


DOI: 10.2174/1566523218666180404161315


Review Article

The relationship between ferroptosis and tumors: A novel landscape for therapeutic approach

, 2019; 19(2): 117-124.

Xiaojun Xia, Xiaoping Fan*, Mingyi Zhao* and Ping Zhu*


DOI: 10.2174/1566523219666190628152137


Research Article

EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs

, 2018; 18(5): 275-285.

Yan Wang, Yinping Xie, Lili Li, Yuan He, Di Zheng, Pengcheng Yu, Ling Yu, Lixu Tang, Yibin Wang* and Zhihua Wang*


DOI: 10.2174/1566523218666181008125010



Review Article

What´s new in gene therapy of hemophilia

, 2018; 18(2): 107-114.

E. Carlos Rodriguez-Merchan*


DOI: 10.2174/1566523218666180214162312


Research Article

A mendelian randomization study on infant length and type 2 diabetes mellitus risk

, 2019; 19(4): 224-231.

He Zhuang, Ying Zhang, Shuo Yang, Liang Cheng* and Shu-Lin Liu*


DOI: 10.2174/1566523219666190925115535



Most Accessed Articles



Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling

, 2019; 19(1): 40-53.

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B. Slayton, Jan S. Moreb, Lujia Dong and Lung-Ji Chang*


DOI: 10.2174/1566523218666181116093857


Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy

, 2019; 19(3): 197-207.

Angela L. McCall*, Sylvia G. Stankov, Gabrielle Cowen, Denise Cloutier, Zizhao Zhang, Lin Yang, Nathalie Clement, Darin J. Falk and Barry J. Byrne*


DOI: 10.2174/1566523219666190621113807


Gene Therapy of Anderson-Fabry Disease

, 2019; 19(1): 3-5.

Antonino Tuttolomondo, Irene Simonetta* and Antonio Pinto


DOI: 10.2174/1566523219999190415160632



Current RNA-based Therapeutics in Clinical Trials

, 2019; 19(3): 172-196.

Ling-Yan Zhou, Zhou Qin, Yang-Hui Zhu, Zhi-Yao He* and Ting Xu*


DOI: 10.2174/1566523219666190719100526







Editor-in-Chief

Lung-Ji Chang
University of Florida
Gainesville, FL
USA

Biography View Full Editorial Board

Journal History

Current Gene Therapy Journal was launched in 2001. Dr. Lung-Ji Chang serves as the Editor-in-Chief of the journal.
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Scopus CiteScore Metrics: 1.62

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