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Current Drug Targets

Volume 21, 16 Issues, 2020
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

Ranking and Category

  • 131st of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 21

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Number 2



Editorial   Open Access



Review Article (Mini-Review)



Review Article



Review Article

Ion Channels as Therapeutic Targets for Type 1 Diabetes Mellitus

, 21(2): 132 - 147

Chandrabose Selvaraj*, Gurudeeban Selvaraj, Satyavani Kaliamurthi, William C. Cho, Dong-Qing Wei* and Sanjeev Kumar Singh*


DOI: 10.2174/1389450119666190920152249


Review Article



General Review Article



General Review Article



General Review Article



Articles Ahead of Print


Understanding the Pharmaceutical Aspects of Dendrimers for the Delivery of Anticancer Drugs


Sunil Kumar Dubey*, Shubham Salunkhe, Mukta Agrawal, Maithili Kali, Gautam Singhvi, Sanjay Tiwari, Swarnlata Saraf, Shailendra Saraf and Amit Alexander*


DOI: 10.2174/1389450120666191031092259
View Abstract View on PubMed







Molecular Mechanism of Resistance to Chemotherapy in Gastric Cancers, the Role of Autophagy


Liudmila V. Spirina*, Alexandra V. Avgustinovich, Sergey G. Afanas’ev, Olga V. Cheremisina, Maxim Yu. Volkov, Evgeny L. Choynzonov, Alexey K. Gorbunov and Evgeny A. Usynin


DOI: 10.2174/1389450120666191127113854
View Abstract View on PubMed


The Potential of PI3K/AKT/mTOR Signaling as a Druggable Target for Endometrial and Ovarian Carcinomas


Csongor György Lengyel*, Sara Cecilia Altuna, Baker Shalal Habeeb, Dario Trapani and Shah Zeb Khan


DOI: 10.2174/1389450120666191120123612
View Abstract View on PubMed


Molecular Mechanisms Involved in the Antitumor Activity of Isolated Lectins from Marine Organisms: A Systematic Review


Hugo Jefferson Ferreira, Evandro Moreira de Almeida, Wildson Max Barbosa da Silva, Edson Holanda Teixeira and Luiz Gonzaga do Nascimento Neto*


DOI: 10.2174/1389450120666191122113850
View Abstract View on PubMed


Abstracts Ahead of Print


Combining growth factor and stem cell therapy for stroke rehabilitation, a review


Samira Asgharzade, Andisheh Talaei, Tahereh Farkhondeh and Fatemeh Forouzanfar*


DOI: 10.2174/1389450121666200107100747
View Abstract


Published Contents

Editor's Choice

Angiotensin Type 1 Receptor Blockers in Heart Failure

, 2020; 21(2): 125 - 131

Khuraijam Dhanachandra Singh* and Sadashiva S. Karnik*


DOI: 10.2174/1389450120666190821152000



Circulating Exosomes and Their Role in Stroke

, 2020; 21(1): 89 - 95

Reza Jafarzadeh-Esfehani, Mohammad Soudyab, Seyed Mostafa Parizadeh, Mohammad Ehsan Jaripoor, Payam Sasan Nejad, Mohammad Shariati and Ariane Sadr Nabavi*


DOI: 10.2174/1389450120666190821153557



Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle

, 2019; 20(16): 1624 - 1635

Jobin Jose, Aaron Mathew Thomas, Darewin Mendonsa, Mohammad M. Al-Sanea, Md. Sahab Uddin, Della Grace Thomas Parambi, R Narayana Charyulu and Bijo Mathew*


DOI: 10.2174/1389450120666190729121747




Anti-TNF and Postoperative Complications in Abdominal Crohn's Disease Surgery

, 2019; 20(13): 1339 - 1348

Takayuki Yamamoto*, Fabio Vieira Teixeira, Rogerio Saad-Hossne, Paulo Gustavo Kotze and Silvio Danese


DOI: 10.2174/1389450120666190404144048





The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

, 2019; 20(10): 1058 - 1067

Mariusz Sikora*, Adriana Rakowska, Małgorzata Olszewska and Lidia Rudnicka


DOI: 10.2174/1389450120666190318121122





Open Access Articles

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695 - 1701

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino




Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles

Review Article

Cyclin-dependent kinase 2 in cellular senescence and cancer. A structural and functional review

, 2019; 20(7): 716-726.

Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


DOI: 10.2174/1389450120666181204165344


Review Article

CDK9 as an appealing target for therapeutic interventions

, 2019; 20(4): 453-464.

Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


DOI: 10.2174/1389450119666181026152221



Review Article

Advances in discovery of PDE10A inhibitors for CNS-related Disorders. Part 1: Overview of the chemical and biological research

, 2019; 20(1): 122-143.

Agnieszka Jankowska, Artur Świerczek, Elżbieta Wyska, Alicja Gawalska, Adam Bucki, Maciej Pawłowski and Grażyna Chłoń-Rzepa*


DOI: 10.2174/1389450119666180808105056




Review Article

Exosomes in therapy: Engineering, pharmacokinetics and future applications

, 2019; 20(1): 87-95.

Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta and Maurizio Federico*


DOI: 10.2174/1389450119666180521100409



Review Article

Autophagy: A promising target for age-related osteoporosis

, 2019; 20(3): 354-365.

Tiantian Wang, Hongchen He, Shaxin Liu, Chengsen Jia, Ziyan Fan, Can Zhong, Jiadan Yu, Honghong Liu and Chengqi He*


DOI: 10.2174/1389450119666180626120852


Review Article

Inhibition of RAGE axis signaling: A pharmacological challenge

, 2019; 20(3): 340-346.

Armando Rojas*, Miguel Morales, Ileana Gonzalez and Paulina Araya


DOI: 10.2174/1389450119666180820105956


Review Article

Melatonin as potential targets for delaying ovarian aging

, 2019; 20(1): 16-28.

Yanzhou Yang*, Hoi-Hung Cheung, Cheng Zhang, Ji Wu and Wai-Yee Chan


DOI: 10.2174/1389450119666180828144843





Review Article

Nanonetworks in biomedical applications

, 2019; 20(8): 800-807.

Jose Luis Marzo*, Josep Miquel Jornet and Massimiliano Pierobon


DOI: 10.2174/1389450120666190115152613



Most Accessed Articles



Bromodomain-Containing Protein 4: A Druggable Target

, 2019; 20(15): 1517-1536.

Yingying Shi, Jingwen Liu, Yuanyuan Zhao, Jiaoxian Cao, Yiming Li* and Fujiang Guo*


DOI: 10.2174/1574885514666190618113519



Recent Progress in Gene Therapy and Other Targeted Therapeutic Approaches for Beta Thalassemia

, 2019; 20(16): 1603-1623.

Eman M. Hamed, Mohamed Hussein Meabed, Usama Farghaly Aly and Raghda R.S. Hussein*


DOI: 10.2174/1389450120666190726155733


Advances in the Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 2: Focus on Schizophrenia

, 2019; 20(16): 1652-1669.

Artur Świerczek, Agnieszka Jankowska, Grażyna Chłoń-Rzepa, Maciej Pawłowski and Elżbieta Wyska*


DOI: 10.2174/1389450120666190801114210



Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695-1701.

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino


DOI: 10.2174/1389450120666190715102510






Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA

View Full Editorial Board

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
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Scopus CiteScore Metrics: 2.56

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