Bentham Science Logo

Track Your Manuscript:


Current Drug Targets

Volume 22, 17 Issues, 2021
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

,

Volume 22

-

Number 1



Biography   Open Access



Editorial   Open Access



Review Article



Review Article

Neoadjuvant Chemotherapy Before Radical Cystectomy: Why We Must Adhere?

, 22(1): 14 - 21

Beppe Calò*, Michele Marchionni, Francesca Sangusedolce, Ugo Giovanni Falagario, Marco Chirico, Giuseppe Carrieri and Luigi Cormio


DOI: 10.2174/1389450121666200802022150


Review Article



Systematic Review Article



Review Article (Mini-Review)

Computational and Biological Investigations on Abl1 Tyrosine Kinase: A Review

, 22(1): 38 - 51

Masilamani Elizabeth Sobhia*, G. Siva Kumar, Antara Mallick, Harmanpreet Singh, Kranthi Kumar, Meenakshi Chaurasiya, Narendra Gera, Sindhuja Deverakonda and Vinay Baghel


DOI: 10.2174/1389450121999201013152513


Review Article (Mini-Review)

COVID-19 and Renal Diseases: An Update

, 22(1): 52 - 67

Letícia Bitencourt Cota, Ana Luisa Pedrosa, Stephanie Bruna Camilo Soares de Brito, Ana Cláudia Fontoura Fróes, Sarah Tayná de Carvalho, Giulio Gori Fonseca, Guilherme Costa Ferreira, Pollyanna Faria Fradico and Ana Cristina Simões e Silva*


DOI: 10.2174/1389450121999201013151300


Current Drug Targets, Volume 22 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Current Drug Targets, Volume 22 (2021) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print




Artificial Intelligence, Big data and Machine Learning approaches in Precision Medicine & Drug Discovery


Anuraj Nayarisseri*, Ravina Khandelwal, Poonam Tanwar, Maddala Madhavi, Diksha Sharma, Garima Thakur, Alejandro Speck-Planche and Sanjeev Kumar Singh


DOI: 10.2174/1389450122999210104205732
View Abstract








Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Neoadjuvant Chemotherapy Before Radical Cystectomy: Why We Must Adhere?

, 2021; 22(1): 14 - 21

Beppe Calò*, Michele Marchioni, Francesca Sanguedolce, Ugo Giovanni Falagario, Marco Chirico, Giuseppe Carrieri and Luigi Cormio


DOI: 10.2174/1389450121666200802022150



The Activating Receptors of Natural Killer Cells and Their Inter-Switching Potentials

, 2020; 21(16): 1733 - 1751

Adekunle Babajide Rowaiye, Titilayo Asala, Angus Nnamdi Oli*, Ikemefuna Chijioke Uzochukwu, Alex Akpa and Charles Okechukwu Esimone


DOI: 10.2174/1389450121666200910160929




Exosomes in Inflammatory Bowel Disease: What Have We Learned So Far?

, 2020; 21(14): 1448 - 1455

Haichao Wang, Chen Ye, Yaling Wu, Pengyu Yang, Chunqiu Chen, Zhanju Liu and Xiaolei Wang*


DOI: 10.2174/1389450121666200428102330



PD1/PD-L1 Axis in Uro-oncology

, 2020; 21(13): 1293 - 1300

Kerstin Junker*, Markus Eckstein, Michelangelo Fiorentino and Rodolfo Montironi


DOI: 10.2174/1389450121666200326123700



Anti-VEGF Treatment in Corneal Diseases

, 2020; 21(12): 1159 - 1180

Giuseppe Giannaccare, Marco Pellegrini, Cristina Bovone, Rossella Spena, Carlotta Senni, Vincenzo Scorcia and Massimo Busin*


DOI: 10.2174/1389450121666200319111710







Open Access Articles

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695 - 1701

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino




Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles


Review Article

Bioinformatics approaches for anti-cancer drug discovery

, 2020; 21(1): 3-17.

Kening Li, Yuxin Du, Lu Li and Dong-Qing Wei*


DOI: 10.2174/1389450120666190923162203


Review Article

Targeting cancer stem cells pathways for the effective treatment of cancer

, 2020; 21(3): 258-278.

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730


Review Article (Mini-Review)

The therapeutic potential of chemokines in the treatment of chemotherapy-induced peripheral neuropathy

, 2020; 21(3): 288-301.

Lin Zhou, Luyao Ao, Yunyi Yan, Wanting Li, Anqi Ye, Yahui Hu*, Weirong Fang* and Yunman Li*


DOI: 10.2174/1389450120666190906153652


Review Article

ACE2/angiotensin-(1-7)/mas receptor axis in human cancer: Potential role for pediatric tumors

, 2020; 21(9): 892-901.

Ana Luiza Ataide Carneiro de Paula Gonzaga , Vitória Andrade Palmeira , Thomas Felipe Silva Ribeiro , Larissa Braga Costa , Karla Emília de Sá Rodrigues and Ana Cristina Simões-e-Silva *


DOI: 10.2174/1389450121666200210124217


Review Article

Nanosized modification strategies for improving the antitumor efficacy of MEK inhibitors

, 2020; 21(3): 228-251.

Yanan Li, Qingrong Dong, Ting Mei, Meichen Zheng, Ramasamy Raj Kumar, Bin Yu, Chunsheng Wu, Hui Zhang* and Feifei An*


DOI: 10.2174/1389450120666190807143245



Review Article (Mini-Review)

Antiviral drug targets of single-stranded rna viruses causing chronic human diseases

, 2020; 21(2): 105-124.

Dhurvas Chandrasekaran Dinesh*, Selvaraj Tamilarasan, Kaushik Rajaram and Evžen Bouřa*


DOI: 10.2174/1389450119666190920153247


General Review Article

Advances in the treatment of ovarian cancer using PARP inhibitors and the underlying mechanism of resistance

, 2020; 21(2): 167-178.

Ling Wang, Qi Wang, Yangchun Xu, Manhua Cui and Liying Han*


DOI: 10.2174/1389450120666190925123507


Editorial

Computational advances in chronic diseases diagnostics and therapy-i

, 2020; 21(1): 1-2.

Gurudeeban Selvaraj, Chandrabose Selvaraj and Dong-Qing Wei


DOI: 10.2174/138945012101191206142040



Review Article

The potential of pi3k/akt/mtor signaling as a druggable target for endometrial and ovarian carcinomas

, 2020; 21(10): 946-961.

Csongor György Lengyel*, Sara Cecilia Altuna, Baker Shalal Habeeb, Dario Trapani and Shah Zeb Khan


DOI: 10.2174/1389450120666191120123612


Review Article

IL-37 as a potential biotherapeutics of inflammatory diseases

, 2020; 21(9): 855-863.

Junhui Bai, Yukun Li, Meixiang Li, Sijie Tan* and Daichao Wu*


DOI: 10.2174/1389450121666200429114926



Review Article

Combining growth factor and stem cell therapy for stroke rehabilita-tion, a review

, 2020; 21(8): 781-791.

Samira Asgharzade, Andisheh Talaei, Tahereh Farkhondeh and Fatemeh Forouzanfar*


DOI: 10.2174/1389450121666200107100747



Most Accessed Articles


Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

, 2020; 21(3): 258-278.

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730



Edaravone May Prevent Ferroptosis in ALS

, 2020; 21(8): 776-780.

Snežana Spasić*, Aleksandra Nikolić-Kokić, Srđan Miletić, Zorana Oreščanin-Dušić, Mihajlo B. Spasić, Duško Blagojević and Zorica Stević


DOI: 10.2174/1389450121666200220123305


The Epigenetic Modification of Epigallocatechin Gallate (EGCG) on Cancer

, 2020; 21(11): 1099-1104.

Linqi Yang, Wenqi Zhang, Saiyam Chopra, Deeepjyot Kaur, Huibing Wang, Meng Li, Pingping Chen* and Wei Zhang*


DOI: 10.2174/1389450121666200504080112



Application of Artificial Intelligence in Targeting Retinal Diseases

, 2020; 21(12): 1208-1215.

Francesco Saverio Sorrentino, Giuseppe Jurman, Katia De Nadai, Claudio Campa, Cesare Furlanello and Francesco Parmeggiani*


DOI: 10.2174/1389450121666200708120646



Medicinal Perspective of Indole Derivatives: Recent Developments and Structure-Activity Relationship Studies

, 2020; 21(9): 864-891.

Devendra Kumar, Sahil Sharma, Sourav Kalra, Gurpreet Singh, Vikramdeep Monga and Bhupinder Kumar*


DOI: 10.2174/1389450121666200310115327


IL-37 As a Potential Biotherapeutics of Inflammatory Diseases

, 2020; 21(9): 855-863.

Junhui Bai, Yukun Li, Meixiang Li, Sijie Tan* and Daichao Wu*


DOI: 10.2174/1389450121666200429114926


Fluoroquinolones: Blessings Or Curses

, 2020; 21(13): 1354-1370.

Priyanka P. Majalekar* and Pramodkumar J. Shirote


DOI: 10.2174/1389450121666200621193355



Chitosan Nanoparticles as a Novel Drug Delivery System: A Review Article

, 2020; 21(15): 1613-1624.

Sina M. Matalqah*, Khalid Aiedeh, Nizar M. Mhaidat, Karem H. Alzoubi, Yasser Bustanji and Islam Hamad


DOI: 10.2174/1389450121666200711172536


Anti-VEGF Treatment in Corneal Diseases

, 2020; 21(12): 1159-1180.

Giuseppe Giannaccare, Marco Pellegrini, Cristina Bovone, Rossella Spena, Carlotta Senni, Vincenzo Scorcia and Massimo Busin*


DOI: 10.2174/1389450121666200319111710


The Potential of PI3K/AKT/mTOR Signaling as a Druggable Target for Endometrial and Ovarian Carcinomas

, 2020; 21(10): 946-961.

Csongor György Lengyel*, Sara Cecilia Altuna, Baker Shalal Habeeb, Dario Trapani and Shah Zeb Khan


DOI: 10.2174/1389450120666191120123612



Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)
View Full Editorial Board

COPE Compliant

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.63

Advertisement

CITATION BOOSTER

Related Journals

Related eBooks

eBooks Catalog