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Current Drug Targets

Volume 21, 16 Issues, 2020
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

Ranking and Category

  • 131st of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 21

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Number 4



Editorial   Open Access



Review Article



Review Article



Review Article



Review Article



Review Article



General Review Article

Candida auris and Nosocomial Infection

, 21(4): 365 - 373

Sweety Dahiya, Anil K. Chhillar*, Namita Sharma, Pooja Choudhary, Aruna Punia, Meenakshi Balhara, Kumar Kaushik and Virinder S. Parmar


DOI: 10.2174/1389450120666190924155631


General Review Article



Current Drug Targets, Volume 21 (2020) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Challenges with Wound Infection Models in Drug Development


Sandeep K Shukla*, Ajay K Sharma, Vanya Gupta, Aman Kalonia and Priyanka Shaw


DOI: 10.2174/1389450121666200302093312
View Abstract View on PubMed



Aromatase Inhibitors for Ovarian Stimulation in Patients with Breast Cancer


Esteban Ferreiro , Belén López de Uralde , Rita Abreu , Juan A García-Velasco and Elkin Muñoz *


DOI: 10.2174/1389450121666200220124607
View Abstract View on PubMed




Is Galanin a Promising Therapeutic Resource for Neural and Nonneural Diseases?


Caroline Maria Oliveira Volpe, Tatiana Vaz, Fabiana Rocha-Silva, Pedro Henrique Villar-Delfino and José Augusto Nogueira-Machado*


DOI: 10.2174/1389450121666200225112055
View Abstract View on PubMed



Edaravone May Prevent Ferroptosis in ALS


Snežana Spasić*, Aleksandra Nikolić-Kokić, Srđan Miletić, Zorana Oreščanin-Dušić, Mihajlo B. Spasić, Duško Blagojević and Zorica Stević


DOI: 10.2174/1389450121666200220123305
View Abstract View on PubMed



ACE2/Angiotensin-(1-7)/Mas Receptor Axis in Human Cancer: Potential Role for Pediatric Tumors


Ana Luiza Ataide Carneiro de Paula Gonzaga , Vitória Andrade Palmeira , Thomas Felipe Silva Ribeiro , Larissa Braga Costa , Karla Emília de Sá Rodrigues and Ana Cristina Simões-e-Silva *


DOI: 10.2174/1389450121666200210124217
View Abstract View on PubMed


Abstracts Ahead of Print

PD1/PD-L1 axis in uro-oncology.


Kerstin Junker*, Markus Eckstein, Michelangelo Fiorentino and Rodolfo Montironi


DOI: 10.2174/1389450121666200326123700
View Abstract




PD1 and PD-L1 Inhibitors for the Treatment of Kidney Cancer: the Role of PD-L1 Assay


Alessia Cimadamore*, Francesco Massari , Matteo Santoni, Antonio Lopez-Beltran , Liang Cheng , Marina Scarpelli, Rodolfo Montironi and Holger Moch


DOI: 10.2174/1389450121666200324151056
View Abstract


Anti-VEGF Treatment in Corneal Diseases


Giuseppe Giannaccare, Marco Pellegrini, Cristina Bovone, Rossella Spena, Carlotta Senni, Vincenzo Scorcia and Massimo Busin*


DOI: 10.2174/1389450121666200319111710
View Abstract



Medicinal Perspective of Indole Derivatives: Recent Developments and Structure-Activity Relationship Studies


Devendra Kumar, Sahil Sharma, Sourav Kalra, Gurpreet Singh, Vikram Deep Monga and Bhupinder Kumar*


DOI: 10.2174/1389450121666200310115327
View Abstract


Immunotherapy and Radiation Therapy in Renal Cell Carcinoma


Veronica Mollica, Matteo Santoni, Vincenzo Di Nunno, Alessia Cimadamore, Liang Cheng, Antonio Lopez-Beltran, Nicola Battelli, Rodolfo Montironi and Francesco Massari*


DOI: 10.2174/1389450121666200311121540
View Abstract


Published Contents

Editor's Choice


Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

, 2020; 21(3): 258 - 278

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730



Angiotensin Type 1 Receptor Blockers in Heart Failure

, 2020; 21(2): 125 - 131

Khuraijam Dhanachandra Singh* and Sadashiva S. Karnik*


DOI: 10.2174/1389450120666190821152000



Circulating Exosomes and Their Role in Stroke

, 2020; 21(1): 89 - 95

Reza Jafarzadeh-Esfehani, Mohammad Soudyab, Seyed Mostafa Parizadeh, Mohammad Ehsan Jaripoor, Payam Sasan Nejad, Mohammad Shariati and Ariane Sadr Nabavi*


DOI: 10.2174/1389450120666190821153557



Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle

, 2019; 20(16): 1624 - 1635

Jobin Jose, Aaron Mathew Thomas, Darewin Mendonsa, Mohammad M. Al-Sanea, Md. Sahab Uddin, Della Grace Thomas Parambi, R Narayana Charyulu and Bijo Mathew*


DOI: 10.2174/1389450120666190729121747




Anti-TNF and Postoperative Complications in Abdominal Crohn's Disease Surgery

, 2019; 20(13): 1339 - 1348

Takayuki Yamamoto*, Fabio Vieira Teixeira, Rogerio Saad-Hossne, Paulo Gustavo Kotze and Silvio Danese


DOI: 10.2174/1389450120666190404144048





The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

, 2019; 20(10): 1058 - 1067

Mariusz Sikora*, Adriana Rakowska, Małgorzata Olszewska and Lidia Rudnicka


DOI: 10.2174/1389450120666190318121122



Open Access Articles

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695 - 1701

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino




Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles

Review Article

Cyclin-dependent kinase 2 in cellular senescence and cancer. A structural and functional review

, 2019; 20(7): 716-726.

Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


DOI: 10.2174/1389450120666181204165344


Review Article

CDK9 as an appealing target for therapeutic interventions

, 2019; 20(4): 453-464.

Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


DOI: 10.2174/1389450119666181026152221


Review Article

Exosomes in therapy: Engineering, pharmacokinetics and future applications

, 2019; 20(1): 87-95.

Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta and Maurizio Federico*


DOI: 10.2174/1389450119666180521100409







Review Article

Advances in discovery of PDE10A inhibitors for CNS-related Disorders. Part 1: Overview of the chemical and biological research

, 2019; 20(1): 122-143.

Agnieszka Jankowska, Artur Świerczek, Elżbieta Wyska, Alicja Gawalska, Adam Bucki, Maciej Pawłowski and Grażyna Chłoń-Rzepa*


DOI: 10.2174/1389450119666180808105056


Review Article

High mobility group box-1 (HMGB1): A potential target in therapeutics

, 2019; 20(14): 1474-1485.

Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt* and Kedar S. Prabhavalkar


DOI: 10.2174/1389450120666190618125100


Review Article

Anti-TNF and postoperative complications in abdominal crohn's disease surgery

, 2019; 20(13): 1339-1348.

Takayuki Yamamoto*, Fabio Vieira Teixeira, Rogerio Saad-Hossne, Paulo Gustavo Kotze and Silvio Danese


DOI: 10.2174/1389450120666190404144048





Review Article

Autophagy: A promising target for age-related osteoporosis

, 2019; 20(3): 354-365.

Tiantian Wang, Hongchen He, Shaxin Liu, Chengsen Jia, Ziyan Fan, Can Zhong, Jiadan Yu, Honghong Liu and Chengqi He*


DOI: 10.2174/1389450119666180626120852



Most Accessed Articles



Advances in the Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 2: Focus on Schizophrenia

, 2019; 20(16): 1652-1669.

Artur Świerczek, Agnieszka Jankowska, Grażyna Chłoń-Rzepa, Maciej Pawłowski and Elżbieta Wyska*


DOI: 10.2174/1389450120666190801114210



Recent Progress in Gene Therapy and Other Targeted Therapeutic Approaches for Beta Thalassemia

, 2019; 20(16): 1603-1623.

Eman M. Hamed, Mohamed Hussein Meabed, Usama Farghaly Aly and Raghda R.S. Hussein*


DOI: 10.2174/1389450120666190726155733


Bromodomain-Containing Protein 4: A Druggable Target

, 2019; 20(15): 1517-1536.

Yingying Shi, Jingwen Liu, Yuanyuan Zhao, Jiaoxian Cao, Yiming Li* and Fujiang Guo*


DOI: 10.2174/1574885514666190618113519




Potential Drug Targets Against Hepatitis B Virus Based on Both Virus and Host Factors

, 2019; 20(16): 1636-1651.

Bing-Yi Zhang, Dan-Ping Chai, Yi-Hang Wu*, Li-Peng Qiu, Yong-Yong Zhang, Zi-Hong Ye and Xiao-Ping Yu


DOI: 10.2174/1389450120666190729115646


Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle

, 2019; 20(16): 1624-1635.

Jobin Jose, Aaron Mathew Thomas, Darewin Mendonsa, Mohammad M. Al-Sanea, Md. Sahab Uddin, Della Grace Thomas Parambi, R Narayana Charyulu and Bijo Mathew*


DOI: 10.2174/1389450120666190729121747




Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA

View Full Editorial Board

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.63

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