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Current Alzheimer Research

Volume 18, 14 Issues, 2021
ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)
This journal supports open access

Aims & Scope

Current Alzheimer Research publishes peer-reviewed frontier review, research, drug clinical trial studies and letter articles on all areas of Alzheimer’s disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer’s disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer’s disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Current Alzheimer Research

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Volume 17

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Number 14





Review Article





Research Article

Enhanced Anti-Amyloid Effect of Combined Leptin and Pioglitazone in APP/PS1 Transgenic Mice

, 17(14): 1294 - 1301

Yao Liu*, Kelsey A. Hanson, Graeme McCormack, Rachel A.K. Atkinson, Justin Dittmann, James C. Vickers, Carmen M. Fernandez-Martos* and Anna E. King


DOI: 10.2174/1567205018666210218163857


Research Article

Nanoparticle-Encapsulated Bryostatin-1 Activates α-Secretase and PKC Isoforms In vitro and Facilitates Acquisition and Retention of Spatial Learning in an Alzheimer's Disease Mouse Model

, 17(14): 1302 - 1310

Lisa Schrott, Ping Yi, Kasey Jackson, Gabriel S. Jackson, Christopher Webb, Alireza Minagar, J. Winny Yun, Geoffrey Purdum, David J. Rios, Theodore A. Tyler, Maria I. Vizcanio, Judith L. Castor, Trevor Castor and Jonathan S. Alexander*


DOI: 10.2174/1567205018666210218155835




Research Article

Neuroprotector Effect of Daily 8-Minutes of High-Intensity Interval Training in Rat Aβ1-42 Alzheimer Disease Model

, 17(14): 1320 - 1333

Francisco S.L. Vasconcelos-Filho*, Roberta C. da Rocha-e-Silva, Jonathan E.R. Martins, Welton D.N. Godinho, Vitor V. da Costa, Jannison K.C. Ribeiro, Carlos A. da Silva, Vania M. Ceccatto, Paula M. Soares and Janaina S.A.M. Evangelista


DOI: 10.2174/1567205018666210218161856




Current Alzheimer Research, Volume 18 (2021) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

There are currently no Articles Ahead of Print available for this journal.

Abstracts Ahead of Print



Weight Loss and the Risk of Dementia: A Meta-analysis of Cohort Studies


Chao Wang, Wenning Fu, Shiyi Cao, Heng Jiang, Yingying Guo, Hongbin Xv, Jianxin Liu, Yong Gan* and Zuxun Lu*


DOI: 10.2174/1567205018666210414112723
View Abstract


PET/MRI Delivers Multimodal Brain Signature in Alzheimer’s Disease with De Novo PSEN1 Mutation


Gayane Aghakhanyan, Dorothee Saur, Michael Rullmann, Christopher M. Weise, Matthias L. Schroeter, Ken Marek, Rami Abou Jamra, Solveig Tiepolt, Maria Strauss, Cordula Scherlach, Karl-Titus Hoffmann, Osama Sabri, Joseph Classen and Henryk Barthel*


DOI: 10.2174/1567205018666210414111536
View Abstract


Cerebrospinal fluid inflammatory markers in Alzheimer’s disease: influence of comorbidities


Ying Wang*, Ceren Emre, Helena Gyllenhammar-Schill, Karin Fjellman, Helga Eyjolfsdottir, Maria Eriksdotter, Marianne Schultzberg and Erik Hjorth*


DOI: 10.2174/1567205018666210330162207
View Abstract


Published Contents

Editor's Choice

Nanoparticle-Encapsulated Bryostatin-1 Activates α-Secretase and PKC Isoforms In vitro and Facilitates Acquisition and Retention of Spatial Learning in an Alzheimer's Disease Mouse Model

, 2020; 17(14): 1302 - 1310

Lisa Schrott, Ping Yi, Kasey Jackson, Gabriel S. Jackson, Christopher Webb, Alireza Minagar, J. Winny Yun, Geoffrey Purdum, David J. Rios, Theodore A. Tyler, Maria I. Vizcanio, Judith L. Castor, Trevor Castor and Jonathan S. Alexander*


DOI: 10.2174/1567205018666210218155835




Diagnosis of Mild Cognitive Impairment Using Cognitive Tasks: A Functional Near-Infrared Spectroscopy Study

, 2020; 17(13): 1145 - 1160

So-Hyeon Yoo, Seong-Woo Woo, Myung-Jun Shin, Jin A. Yoon, Yong-Il Shin and Keum-Shik Hong*


DOI: 10.2174/1567205018666210212154941








Statins, Risk of Death and Ischemic Stroke in Patients with Dementia: A Registry-Based Observational Cohort Study

, 2020; 17(10): 881 - 892

Bojana Petek*, Hong Xu, Marta Villa-Lopez, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek*


DOI: 10.2174/1567205017666201215130254



The Prion-like Properties of Amyloid-beta Peptide and Tau: Is there Any Risk of Transmitting Alzheimer's Disease During Neurosurgical Interventions?

, 2020; 17(9): 781 - 789

Huber S. Padilla-Zambrano, Ezequiel García-Ballestas, Gabriel A. Quiñones-Ossa, Andrés E. Sibaja-Perez, Amit Agrawal, Luis R. Moscote-Salazar and Manuel Menéndez-González*


DOI: 10.2174/1567205017666201204164220



Open Access Articles


Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China

, 2020; 17(6): 540 - 546

Jiajia Zhou, Yi Chen, Fanxia Meng, Kan Zhang, Xiaoyan Liu and Guoping Peng*




The Parietal Atrophy Score on Brain Magnetic Resonance Imaging is a Reliable Visual Scale

, 2020; 17(6): 534 - 539

David Silhan, Ales Bartos*, Jana Mrzilkova, Olga Pashkovska, Ibrahim Ibrahim and Jaroslav Tintera





Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

, 2020; 17(3): 285 - 296

Gernot Riedel , Jochen Klein , Grazyna Niewiadomska, Constantin Kondak , Karima Schwab , Dilyara Lauer , Mandy Magbagbeolu , Marta Steczkowska, Maciej Zadrozny , Malgorzata Wydrych , Anna Cranston , Valeria Melis, Renato X. Santos , Franz Theuring , Charles R. Harrington and Claude M. Wischik*




Dangerous Liaisons: Tau Interaction with Muscarinic Receptors

, 2020; 17(3): 224 - 237

Adrianna Wysocka, Ewelina Palasz, Marta Steczkowska and Grazyna Niewiadomska*




Association Between Anemia and Dementia: A Nationwide, Populationbased Cohort Study in Taiwan

, 2020; 17(2): 196 - 204

Chien-Tai Hong, Yi-Chen Hsieh, Hung-Yi Liu, Hung-Yi Chiou and Li-Nien Chien*




Joint Effect of ABCA7 rs4147929 and Body Mass Index on Progression from Mild Cognitive Impairment to Alzheimer’s Disease: The Shanghai Aging Study

, 2020; 17(2): 185 - 195

Jianxiong Xi, Ding Ding*, Qianhua Zhao, Xiaoniu Liang, Li Zheng, Qihao Guo, Zhen Hong, Hua Fu, Jianfeng Xu and Qianyi Xiao*




Intracranial Atherosclerotic Stenosis is Related to Post-stroke Cognitive Impairment: A Cross-sectional Study of Minor Stroke

, 2020; 17(2): 177 - 184

Li Gong, Haichao Wang, Qiong Dong, Xiaoping Zhu, Xiaoran Zheng, Yongzhe Gu, Wangli Cai, Yanxin Zhao* and Xueyuan Liu*




Automatic Detection of Cognitive Impairments through Acoustic Analysis of Speech

, 2020; 17(1): 60 - 68

Ryosuke Nagumo*, Yaming Zhang, Yuki Ogawa, Mitsuharu Hosokawa, Kengo Abe, Takaaki Ukeda, Sadayuki Sumi, Satoshi Kurita, Sho Nakakubo, Sangyoon Lee, Takehiko Doi and Hiroyuki Shimada




Tau PET Distributional Pattern in AD Patients with Visuospatial Dysfunction

, 2019; 16(11): 1055 - 1062

Xi Sun, Binbin Nie, Shujun Zhao, Qian Chen, Panlong Li, Tianhao Zhang, Tingting Pan, Ting Feng, Luying Wang, Xiaolong Yin, Wei Zhang, Shilun Zhao, Baoci Shan, Hua Liu*, Shengxiang Liang*, Lin Ai* and Guihong Wang*







Heterogeneity in Cost-Effectiveness Analysis of Vaccination for Mild and Moderate Alzheimer’s Disease

, 2019; 16(6): 495 - 504

Chung-Hsien Lin, Jean Ching-Yuan Fann, Sam Li-Sheng Chen, Hsiu-Hsi Chen and Kuen-Cheh Yang*





Most Cited Articles

Systematic Review Article

Depression in dementia or dementia in depression? Systematic review of studies and hypotheses

, 2020; 17(1): 16-28.

Agnieszka Brzezińska, Julius Bourke, Rayito Rivera-Hernández, Magda Tsolaki, Joanna Wożniak and Jakub Każmierski*


DOI: 10.2174/1567205017666200217104114


Review Article

Learning from the past: A review of clinical trials targeting amyloid, tau and neuroinflammation in Alzheimer’s disease

, 2020; 17(2): 112-125.

Kelly Ceyzériat, Thomas Zilli, Philippe Millet, Giovanni B. Frisoni, Valentina Garibotto and Benjamin B. Tournier*


DOI: 10.2174/1567205017666200304085513


Review Article

Genetic variants and oxidative stress in alzheimer’s disease

, 2020; 17(3): 208-223.

Marta Kowalska*, Katarzyna Wize, Michał Prendecki, Margarita Lianeri, Wojciech Kozubski and Jolanta Dorszewska


DOI: 10.2174/1567205017666200224121447


Research Article

Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model

, 2020; 17(3): 285-296.

Gernot Riedel , Jochen Klein , Grazyna Niewiadomska, Constantin Kondak , Karima Schwab , Dilyara Lauer , Mandy Magbagbeolu , Marta Steczkowska, Maciej Zadrozny , Malgorzata Wydrych , Anna Cranston , Valeria Melis, Renato X. Santos , Franz Theuring , Charles R. Harrington and Claude M. Wischik*


DOI: 10.2174/1567205017666200224120926



Review Article

Risk reduction and prevention of alzheimer's disease: Biological mechanisms of diet

, 2020; 17(5): 407-427.

Hugo McGurran, Jordan Glenn, Erica Madero and Nick Bott*


DOI: 10.2174/1567205017666200624200651


Review Article

Reversal of calcium dysregulation as potential approach for treating alzheimer's disease

, 2020; 17(4): 344-354.

Elena Popugaeva, Daria Chernyuk and Ilya Bezprozvanny*


DOI: 10.2174/1567205017666200528162046


Research Article

Automatic detection of cognitive impairments through acoustic analysis of speech

, 2020; 17(1): 60-68.

Ryosuke Nagumo*, Yaming Zhang, Yuki Ogawa, Mitsuharu Hosokawa, Kengo Abe, Takaaki Ukeda, Sadayuki Sumi, Satoshi Kurita, Sho Nakakubo, Sangyoon Lee, Takehiko Doi and Hiroyuki Shimada


DOI: 10.2174/1567205017666200213094513


Review Article

Microglia in Alzheimer’s disease

, 2020; 17(1): 29-43.

Patrick Süß and Johannes C.M. Schlachetzki*


DOI: 10.2174/1567205017666200212155234



Research Article

The association between TNF-alpha, IL-1 alpha and il-10 with alzheimer's disease

, 2020; 17(11): 972-984.

Marija Culjak, Matea N. Perkovic, Suzana Uzun, Dubravka S. Strac, Gordana N. Erjavec, Mirjana B. Leko, Goran Simic, Lucija Tudor, Marcela Konjevod, Oliver Kozumplik, Ninoslav Mimica and Nela Pivac*


DOI: 10.2174/1567205017666201130092427



Review Article

Mitochondrial calcium signaling as a therapeutic target for alzheimer’s disease

, 2020; 17(4): 329-343.

Aston J. Wu, Benjamin C.-K. Tong, Alexis S. Huang, Min Li and King-Ho Cheung*


DOI: 10.2174/1567205016666191210091302


Review Article

Dangerous liaisons: Tau interaction with muscarinic receptors

, 2020; 17(3): 224-237.

Adrianna Wysocka, Ewelina Palasz, Marta Steczkowska and Grazyna Niewiadomska*


DOI: 10.2174/1567205017666200424134311


Research Article

Anticholinesterase and antioxidant activities of natural abietane diterpenoids with molecular docking studies

, 2020; 17(3): 269-284.

Gülaçtı Topçu*, Atilla Akdemir, Ufuk Kolak, Mehmet Öztürk, Mehmet Boğa, Fatemeh Bahadori and Seda Damla Hatipoğlu Çakmar


DOI: 10.2174/1567205017666200424133534



Most Accessed Articles


Volumetric MRI Demonstrates Atrophy of the Olfactory Cortex in AD

, 2020; 17(10): 904-915.

Majed Al-Otaibi, Melissa Lessard-Beaudoin, Christian-Alexandre Castellano, Denis Gris, Stephen C. Cunnane and Rona K. Graham*


DOI: 10.2174/1567205017666201215120909








Elucidating the Risk Factors for Progression from Amyloid-Negative Amnestic Mild Cognitive Impairment to Dementia

, 2020; 17(10): 893-903.

Hyung-Ji Kim, Jae-Hong Lee*, E-nae Cheong, Sung-Eun Chung, Sungyang Jo, Woo-Hyun Shim and Yun J. Hong


DOI: 10.2174/1567205017666201130094259







Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer’s Disease

, 2020; 17(4): 393-406.

Gregory Z. Ferl*, Reina N. Fuji, Jasvinder K. Atwal, Tony Sun, Saroja Ramanujan and Angelica L. Quartino


DOI: 10.2174/1567205017666200302122307




Editor-in-Chief

graphic
Prof. Debomoy K. Lahiri
(16607 citations)
Neuroscience Research Center
Indianapolis, IN 46202
(USA)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

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Prof. Jean-Marie Lehn
(France)

graphic
Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Alzheimer Research was introduced in 2004 with the assistance of Dr. Debomoy K. Lahiri, who is the current Editor-in-Chief serving since 2004.
New eBook

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Frontiers in Clinical Drug Research – Alzheimer Disorders



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