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"All chemists and scientists will welcome Anti-Cancer Agents in Medicinal Chemistry as a fresh and vital source of information for this important field. The journal is highly recommended for essential reading."

Terrence C. Jenkins
YCR Laboratory of Drug Design, UK

Forthcoming Special Issues

Anti-Cancerous Heterocycles in Focus


Guest Editor(s): Girish Kumar Gupta, Vipin Saini, Prabodh Chander Sharma, Fidele Ntie-Kang
Tentative Publication Date: November, 2018
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Special Issues - In-Press
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Published Special Issues

Radiopharmaceuticals for Cancer Therapy and Diagnosis


Anti-Cancer Agents in Medicinal Chemistry, Volume 17, Number 3
Guest Editor(s): Ralph Santos-Oliveira

Authors' Comments
Thank you for the services I got at Bentham Science. It was a great experience publishing my paper entitled" Doxycycline As Potential Anti-cancer Agent" in the Journal "Anti-Cancer Agents In Medicinal Chemistry

Isra Ali
(Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan)


Anti-Cancer Agents in Medicinal Chemistry

,

Volume 18

-

Number 6



Biography   Open Access



Editorial   Open Access



Review Article



Research Article



Research Article



Research Article



Research Article



Research Article

Cold Physical Plasma-Treated Buffered Saline Solution as Effective Agent Against Pancreatic Cancer Cells

, 18(6): 824 - 831

Sander Bekeschus*, André Käding, Tim Schröder, Kristian Wende, Christine Hackbarth, Kim R. Liedtke, Julia van der Linde, Thomas von Woedtke, Claus-Dieter Heidecke and Lars-Ivo Partecke


DOI: 10.2174/1871520618666180507130243




Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Anti-Cancer Agents in Medicinal Chemistry, Volume 18 (2018) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


New Strategies for Therapeutic Cancer Vaccines


Jiyao Sheng, Hanjiao Qin, Dan Zhang, Xuewen Zhang, Linlin Liu and Bingjin Li*


View Abstract View on PubMed


Silimarin and Cancer


Christina Liakopoulou, Christos Kazazis and Natalia G. Vallianou*


View Abstract View on PubMed


Chlorambucil Cytotoxicity Reduction in Rats Through Bone Marrow, An In vivo Study


Ebtesam H.O. Nafie*, Eman Khater, Mohamed Awwad, Mohamed Zowail and Kholud Hegazy


View Abstract View on PubMed


Synthesis and Investigation of the Role of Benzopyran Dihydropyrimidinone Hybrids in Cell Proliferation, Migration and Tumor Growth


Ashutosh K. Dash, Debasis Nayak, Nazar Hussain, Mubashir Javed Mintoo, Sumera Bano, Archana Katoch, Dilip Manikaro Mondhe, Anindya Goswami and Debaraj Mukherjee*


View Abstract View on PubMed



Celastrus Orbiculatus Extract Potentiates The Sensitivity Of Cisplatin Via Caspase-Depenent Apoptosis In Gastric Cancer


Weimin Wang, Yan Zhou, Qiang Yao, Weihua Liu, Liangliang Xiang, Tengyang Ni, Xiaojun Dai and Yanqing Liu*


View Abstract View on PubMed


A Comparison of the Inhibitory Effects of Anti-Cancer Drugs on Thioredoxin Reductase and Glutathione S-Transferase in Rat Liver


Ilknur Ozgencli, Deryanur Kilic, Ugur Guller, Mehmet Ciftci, Omer Irfan Kufrevioglu and Harun Budak*


View Abstract View on PubMed




Abstracts Ahead of Print

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy)methyl)-N-hydroxybenzamides / propenamides as Histone Deacetylase Inhibitors and Antitumor Agents


Duong Tien Anh, Nguyen Thi Thuan, Pham-The Hai, Le-Thi-Thu Huong, Nguyen Thi Kim Yen, Byung Woo Han, Eun Jae Park, Yeo Jin Choi, Jong Soon Kang, Van Thi My Hue*, Sang-Bae Han* and Nguyen-Hai Nam*


View Abstract




Synthesis of asymmetric 1-thiocarbamoyl pyrazoles as potent anti colon cancer, antioxidant and anti-inflammatory agent


Dattatraya G. Raut, Sandeep B. Patil, Vikas D. Kadu, Mahesh G. Hublikar and Raghunath B. Bhosale*


View Abstract


Hybridized quinoline derivatives as anticancer agents: Design, Synthesis, biological evaluation and molecular docking


Mohamed R. Selim, Medhat A. Zahran, Amany Belal*, Mostafa S. Mostafa*, Said A. Shedid, Ahmed B. M. Mehany, Gameel A. M. Elhagali and Yousry A. Ammar*


View Abstract


Determination of Usnic Acid Responsive miRNAs in Breast Cancer Cell Lines


Nil Kiliç, Yasemin Oztemur Islakoglu, İlker Buyuk, Bala Gur-Dedeoglu and Demet Cansaran-Duman*


View Abstract



Peptide R18H from Brn-2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo And Induces Apoptosis in B16F10-Nex2 Cells


Fernanda Fernandes Miranda da Cunha, Katia Cristina Ugolini Mugnol, Filipe Menegatti de Melo , Marta Verônica da Silva Queiroz Nascimento, Ricardo Alexandre de Azevedo, Raquel Tamires Soares Santos, Jéssica Aparecida Magalhães, Danilo Ciccone Miguel , Dayane Batista Tada, Renato Arruda Mortara, Luiz Rodolpho Travassos and Denise Costa Arruda*


View Abstract


Hybrid Magnetic Nanostructures For Cancer Diagnosis And Therapy


Ardelean Lavinia Ioana, Denisa Ficai*, Maria Sonmez, Mihail Aurel Titu, Ovidiu Oprea, Gheorghe Nechifor, Anton Ficai and Ecaterina Andronescu


View Abstract


The anticancer role of omega-3 polyunsaturated fatty acids was closely associated with the increase of genomic DNA hydroxymethylation


Qionglin Huang, Mingming Mo, Yu Zhong, Qingjin Yang, Junjie Zhang, Xiaoxia Ye, Lijian Zhang and Chun Cai*


View Abstract View on PubMed


Editor's Choice



Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents

, 2018; 18(4): 556 - 564

Nikhil R. Madadi, Narsimha R. Penthala, Amit Ketkar, Robert L. Eoff, Vicenta Trujullo-Alonso, Monica L. Guzman and Peter A. Crooks*


DOI: 10.2174/1871521409666170412115703




Novel Findings of Anti-cancer Property of Propofol

, 2018; 18(2): 156 - 165

Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*


DOI: 10.2174/1871520617666170912120327



Evaluation of the in vitro Chemosensitivity and Correlation with Clinical Outcomes in Lung Cancer using the ATP-TCA

, 2018; 18(1): 139 - 145

Zhiyao Chen, Shichao Zhang, Sheng Ma, Chang Li, Chun Xu, Yinfang Shen, Jun Zhao* and Liyan Miao*


DOI: 10.2174/1871520617666170419123713



4-aryl/heteroaryl-4H-fused Pyrans as Anti-proliferative Agents: Design, Synthesis and Biological Evaluation

, 2018; 18(1): 57 - 73

Dinesh Kumar*, Gurpreet Singh, Pooja Sharma, Arem Qayum, Girish Mahajan, M.J. Mintoo, Shashank Kumar Singh, Dilip Manikrao Mondhe, P.M.S. Bedi, Subheet K. Jain and Girish Kumar Gupta


DOI: 10.2174/1871520617666170918143911



Tetrazole Derivatives as Promising Anticancer Agents

, 2017; 17(14): 1856 - 1868

Elena A. Popova*, Aleksandra V. Protas and Rostislav E. Trifonov


DOI: 10.2174/1871520617666170327143148



The Oxime Derivatives of 1-R-1H-Naphtho[2,3-d][1,2,3]triazole-4,9-dione 2-oxides: Synthesis and Properties

, 2017; 17(13): 1814 - 1823

Leonid M. Gornostaev*, Vladimir B. Tsvetkov, Alina A. Markova, Tatyana I. Lavrikova, Yulia G. Khalyavina, Anastasia S. Kuznetsova, Dmitry N. Kaluzhny, Alexei V. Shunayev, Maria V. Tsvetkova, Valeria A. Glazunova, Vladimir V. Chernyshev and Alexander A. Shtil*


DOI: 10.2174/1871520617666170327112216



Synthesis and Evaluation of Antioxidant and Cytotoxicity of the N-Mannich Base of Berberine Bearing Benzothiazole Moieties

, 2017; 17(12): 1652 - 1660

Bhupendra M. Mistry, Han-Seung Shin, Young-Soo Keum, Muthuraman Pandurangan, Doo Hwan Kim, So Hyun Moon, Avinash A. Kadam, Surendra K. Shinde and Rahul V. Patel*


DOI: 10.2174/1871520617666170710180549



Open Access Articles

The Cross-talk between Tristetraprolin and Cytokines in Cancer

, 2017; 17(11): 1477 - 1486

Jian Guo, Hao Wang, Shiyi Jiang, Jiazeng Xia * and Shimao Jin *




Novel Thiourea Derivatives Bearing Sulfonamide Moiety as Anticancer Agents Through COX-2 Inhibition

, 2017; 17(10): 1411 - 1425

Mostafa M. Ghorab*, Mohamed S.A. El-Gaby, Mansour S. Alsaid, Yaseen A.M.M. Elshaier, Aiten M. Soliman , Fardous F. El-Senduny , Farid A. Badria and Abdelrahman Y.A. Sherif




Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors

, 2017; 17(10): 1351 - 1356

Tobias Bartscht, Benjamin Rosien, Dirk Rades, Roland Kaufmann, Harald Biersack, Hendrik Lehnerta and Hendrik Ungefroren*




Cytokine Status of Serum in Ovarian Cancer Patients with Different Tumor Neoadjuvant Chemotherapy Response

, 2017; 17(9): 1251 - 1255

Inna I. Antoneeva, Tatyana V. Abakumova, Dinara R. Dolgova, Tatyana P. Gening*, Sabina S. Pirmamedova, Dinara F. Myasnikova and Snezhanna O. Gening





Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer

, 2016; 16(11): 1426 - 1434

Shiyu Jiang, Chunhua Ling, Wei Li, Hongxin Jiang, Qiaoming Zhi and Min Jiang




Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals

, 2016; 16(11): 1385 - 1402

Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante




Flavonoids with Therapeutic Potential in Prostate Cancer

, 2016; 16(10): 1205 - 1229

Bao Vue, Sheng Zhang and Qiao-Hong Chen




Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

, 2016; 16(7): 810 - 815

Anna Lisa Iorio, Martina da Ros, Ornella Fantappiè, Maurizio Lucchesi, Ludovica Facchini, Alessia Stival, Sabrina Becciani, Milena Guidi, Claudio Favre, Maurizio de Martino, Lorenzo Genitori and Iacopo Sardi




The Use of Anthracyclines for Therapy of CNS Tumors

, 2015; 15(6): 721 - 727

Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi






Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment

, 2014; 14(8): 1121 - 1127

Bryan Oronsky, Neil Oronsky, Susan Knox, Gary Fanger and Jan Scicinski




Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

, 2014; 14(6): 840 - 851

Georgina A. Cardama, Maria J. Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G. Turjanski, Daniel F. Alonso, Daniel E. Gomez and Pablo Lorenzano Menna




β2-Microglobulin-mediated Signaling as a Target for Cancer Therapy

, 2014; 14(3): 343 - 352

Takeo Nomura, Wen-Chin Huang, Haiyen E. Zhau, Sajni Josson, Hiromitsu Mimata and Leland W. K. Chung





Most Cited Articles

Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways

, 2014; 14(1): 77-96.

Andrzej T. Slominski, Michal A. Zmijewski, Igor Semak, Blazej Zbytek, Alexander Pisarchik, Wei Li, Jordan Zjawiony and Robert C. Tuckey


DOI: 10.2174/18715206113139990308




Chemical Metabolic Inhibitors for the Treatment of Blood-Borne Cancers

, 2014; 14(2): 223-232.

Martin Villalba, Nuria Lopez-Royuela, Ewelina Krzywinska, Moeez G. Rathore, Robert A. Hipskind, Houda Haouas and Nerea Allende-Vega


DOI: 10.2174/18715206113136660374


CCL21 and IFNγ Recruit and Activate Tumor Specific T cells in 3D Scaffold Model of Breast Cancer

, 2014; 14(2): 204-210.

Vy Phan-Lai, Forrest M. Kievit, Stephen J. Florczyk, Kui Wang, Mary L. Disis and Miqin Zhang


DOI: 10.2174/18715206113136660375




Most Accessed Articles




Natural Compounds in the Chemoprevention of Malignant Melanoma

, 2018; 18(5): 631-644.

Corina Danciu*, Codruta Soica, Diana Antal, Ersilia Alexa, Ioana Z. Pavel, Roxana Ghiulai, Florina Ardelean, Roxana M. Babuta, Alexandra Popescu and Cristina A. Dehelean


DOI: 10.2174/1871520617666171121142522


BRCA1 as Target for Breast Cancer Prevention and Therapy

, 2015; 15(1): 4-14.

Alberto P.G. Romagnolo, Donato F. Romagnolo and Ornella I. Selmin


DOI: 10.2174/1871520614666141020153543





Natural Macromolecules with Protective and Antitumor Activity

, 2018; 18(5): 675-683.

Cioanca Oana, Trifan Adriana, Cornelia Mircea*, Scripcariu Dragos and Hancianu Monica


DOI: 10.2174/1871520618666180425115029



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