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Current Neuropharmacology

Volume 19, 12 Issues, 2021
ISSN: 1875-6190 (Online)
ISSN: 1570-159X (Print)
This journal supports open access

Aims & Scope

Current Neuropharmacology aims to provide current, comprehensive/mini reviews and guest edited issues of all areas of neuropharmacology and related matters of neuroscience. The reviews cover the fields of molecular, cellular, and systems/behavioural aspects of neuropharmacology and neuroscience.

The journal serves as a comprehensive, multidisciplinary expert forum for neuropharmacologists and neuroscientists.

Current Neuropharmacology

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Volume 19

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Number 4













Review Article

Alzheimer’s Disease: New Concepts on the Role of Autoimmunity and NLRP3 Inflammasome in the Pathogenesis of the Disease

, 19(4): 498 - 512

Cinzia Severini*, Christian Barbato, Maria Grazia Di Certo, Francesca Gabanella, Carla Petrella, Arianna Di Stadio, Marco de Vincentiis, Antonella Polimeni, Massimo Ralli and Antonio Greco


DOI: 10.2174/1570159X18666200621204546


Review Article

Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications

, 19(4): 513 - 537

Raúl Ortiz, Gloria Perazzoli, Laura Cabeza, Cristina Jiménez-Luna, Raquel Luque, Jose Prados* and Consolación Melguizo


DOI: 10.2174/1570159X18666200626204005


Systematic Review Article

Effects of Risperidone in Autistic Children and Young Adults: A Systematic Review and Meta-Analysis

, 19(4): 538 - 552

Brayan Jonas Mano-Sousa, Alessandra Moraes Pedrosa, Bruna Cristina Alves, José Carlos Fernandes Galduróz, Vinícius Silva Belo, Valéria Ernestânia Chaves and Joaquim Maurício Duarte-Almeida*


DOI: 10.2174/1570159X18666200529151741


Current Neuropharmacology, Volume 19 (2021) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Vortioxetine vs. Other Antidepressants in Patients with Major Depressive Episode With or Without Substance Use Disorder


Georgios D. Kotzalidis*, Ginevra Lombardozzi, Marta Matrone, Emanuela Amici, Filippo Perrini, Ilaria Cuomo and Sergio De Filippis


DOI: 10.2174/1570159X19666210113150123
View Abstract View on PubMed





Targeting Glioblastoma: The Current State of Different Therapeutic Approaches


Imran Khan, Sadaf Mahfooz, Elif Burce Elbasan, Busra Karacam, Mustafa Namik Oztanir and Mustafa Aziz Hatiboglu*


DOI: 10.2174/1570159X19666210113152108
View Abstract View on PubMed




The Endocannabinoid System as Modulator of Exercise Benefits in Mental Health


Sandra Amatriain-Fernández*, Henning Budde*, Thomas Gronwald, Carla Quiroga, Cristina Carreón, Gerardo Viana-Torre, Tetsuya Yamamoto, Claudio Imperatori, Sérgio Machado and Eric Murillo-Rodríguez*


DOI: 10.2174/1570159X19666201218112748
View Abstract



Therapeutic Potential Of Multifunctional Derivatives Of Cholinesterase Inhibitors


Maja Przybyłowska, Krystyna Dzierzbicka, Szymon Kowalski, Klaudia Chmielewska and Iwona Inkielewicz-Stepniak*


DOI: 10.2174/1570159X19666201218103434
View Abstract


Abstracts Ahead of Print

Synthetic cannabinoids and cathinones cardiotoxicity: evidences actualities and perspectives


Davide Radaelli, Alessandro Manfredi, Martina Zanon, Paolo Fattorini, Matteo Scopetti, Margherita Neri, Paolo Frisoni and Stefano D’Errico*


DOI: 10.2174/1570159X19666210412101929
View Abstract


Potential of medicinal plants as neuroprotective and therapeutic properties against amyloid-β-related toxicity, and glutamate-induced excitotoxicity in human neural cells


Devina Lobine, Nabeelah Sadeer, Sharmeen Jugreet, Shanoo Suroowan, Bibi Sumera Keenoo, Muhammad Imran, Katharigatta N Venugopala, Faten Mohamed Ibrahim, Gokhan Zengin and Mohamad Fawzi Mahomoodally*


DOI: 10.2174/1570159X19666210412095251
View Abstract


siRNA Therapeutics: Future Promise for Neurodegenerative Diseases


Atefeh Amiri, George E. Barreto, Thozhukat Sathyapalan and Amirhossein Sahebkar*


DOI: 10.2174/1570159X19666210402104054
View Abstract




In vitro, In vivo and Ex vivo Models for Peripheral Nerve Injury and Regeneration


Andrew Li, Clifford Pereira, Elise Eleanor Hill, Olivia Vukcevich and Aijun Wang *


DOI: 10.2174/1570159X19666210407155543
View Abstract


Development of Non-opioid Analgesics Targeting Two-pore Domain Potassium Channels


Lu Huang, Guangyin Xu*, Ruotian Jiang*, Yuncheng Luo , Yunxia Zuo and Jin Liu


DOI: 10.2174/1570159X19666210407152528
View Abstract




The benzydamine experience: a systematic review of benzydamine abuse


Stefania Chiappini, Andrea Miuli, Alessio Mosca, Mauro Pettorruso, Amira Guirguis, John Martin Corkery, Giovanni Martinotti, Massimo Di Giannantonio and Fabrizio Schifano*


DOI: 10.2174/1570159X19666210113151136
View Abstract


Published Contents

Editor's Choice

Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications

, 2021; 19(4): 513 - 537

Raúl Ortiz, Gloria Perazzoli, Laura Cabeza, Cristina Jiménez-Luna, Raquel Luque, Jose Prados* and Consolación Melguizo


DOI: 10.2174/1570159X18666200626204005



Neurophysiological Mechanisms Related to Pain Management in Bone Tumors

, 2021; 19(3): 308 - 319

Pablo Romero-Morelos, Erika Ruvalcaba-Paredes, David Garciadiego-Cázares, Martín Pérez-Santos, Samuel Reyes-Long, Alfonso Alfaro-Rodriguez, Mauricio Salcedo, Javier Mancilla-Ramírez and Cindy Bandala*


DOI: 10.2174/1570159X18666201111112748




Current Understanding of Central Nervous System Drainage Systems: Implications in the Context of Neurodegenerative Diseases

, 2020; 18(11): 1054 - 1063

Vladimir N. Nikolenko , Marine V. Oganesyan, Angela D. Vovkogon, Arina T. Nikitina, Ekaterina A. Sozonova, Valentina A. Kudryashova, Negoria A. Rizaeva, Ricardo Cabezas, Marco Avila-Rodriguez, Margarita E. Neganova, Liudmila M. Mikhaleva, Sergey O. Bachurin, Siva G. Somasundaram, Cecil E. Kirkland, Vadim V. Tarasov and Gjumrakch Aliev*


DOI: 10.2174/1570159X17666191113103850



‘New/Designer Benzodiazepines’: An Analysis of the Literature and Psychonauts’ Trip Reports

, 2020; 18(9): 809 - 837

Laura Orsolini*, John M. Corkery, Stefania Chiappini, Amira Guirguis, Alessandro Vento, Domenico De Berardis, Duccio Papanti and Fabrizio Schifano


DOI: 10.2174/1570159X18666200110121333




Current and Future Neuropharmacological Options for the Treatment of Essential Tremor

, 2020; 18(6): 518 - 537

Hortensia Alonso-Navarro, Elena García-Martín , José A.G. Agúndez and Félix J. Jiménez-Jiménez*


DOI: 10.2174/1570159X18666200124145743



The Ambiguous Role of Microglia in Aβ Toxicity: Chances for Therapeutic Intervention

, 2020; 18(5): 446 - 455

Sara Merlo, Simona Federica Spampinato, Grazia Ilaria Caruso and Maria Angela Sortino*


DOI: 10.2174/1570159X18666200131105418




The Contribution of Formyl Peptide Receptor Dysfunction to the Course of Neuroinflammation: A Potential Role in the Brain Pathology

, 2020; 18(3): 229 - 249

Ewa Trojan, Natalia Bryniarska, Monika Leśkiewicz, Magdalena Regulska, Katarzyna Chamera, Magdalena Szuster-Głuszczak, Marcello Leopoldo, Enza Lacivita and Agnieszka Basta-Kaim*


DOI: 10.2174/1570159X17666191019170244



Open Access Articles


C-terminus of Hsp70 Interacting Protein (CHIP) and Neurodegeneration: Lessons from the Bench and Bedside

, 2021; 19: 1 - 30 (E-Pub Ahead of Print)

Sivakami Mylvaganam, Rebecca Earnshaw, Gregory Heymann, Suneil K. Kalia and Lorraine V. Kalia*




Repetitive Transcranial Magnetic Stimulation Combined with Antidepressants for the First Episode of Major Depressive Disorder

, 2020; 18(9): 852 - 860

Benchalak Maneeton *, Narong Maneeton , Pakapan Woottiluk and Surinporn Likhitsathian




Synaptic Elimination in Neurological Disorders

, 2019; 17(11): 1071 - 1095

Pablo L. Cardozo, Izabella B. Q. de Lima, Esther M.A. Maciel, Nathália C. Silva, Tomas Dobransky and Fabíola M. Ribeiro*




Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?

, 2019; 17(11): 1004 - 1020

Estefania Gastaldello Moreira*, Karine Maria Boll, Dalmo Guilherme Correia, Janaina Favaro Soares, Camila Rigobello and Michael Maes









Relevance of CYP2C9 Function in Valproate Therapy

, 2019; 17(1): 99 - 106

Katalin Monostory*, Andrea Nagy, Katalin Tóth, Tamás Bűdi , Ádám Kiss, Máté Déri and Gábor Csukly





The Role of IRE1 Signaling in the Central Nervous System Diseases

, 2018; 16(9): 1340 - 1347

Haibo Ni, Qin Rui, Di Li*, Rong Gao and Gang Chen







Most Cited Articles


Review Article

The “entourage effect”: Terpenes coupled with cannabinoids for the treatment of mood disorders and anxiety disorders

, 2020; 18(2): 87-96.

Sari Goldstein Ferber, Dvora Namdar, Danielle Hen-Shoval, Gilad Eger, Hinanit Koltai, Gal Shoval*, Liat Shbiro and Aron Weller


DOI: 10.2174/1570159X17666190903103923


Review Article

‘New/Designer Benzodiazepines’: An Analysis of the Literature and Psychonauts’ Trip Reports

, 2020; 18(9): 809-837.

Laura Orsolini*, John M. Corkery, Stefania Chiappini, Amira Guirguis, Alessandro Vento, Domenico De Berardis, Duccio Papanti and Fabrizio Schifano


DOI: 10.2174/1570159X18666200110121333


Review Article

Pharmacologic overview of chlorogenic acid and its metabolites in chronic pain and inflammation

, 2020; 18(3): 216-228.

Deniz Bagdas*, Zulfiye Gul, Julie A. Meade, Betul Cam, Nilufer Cinkilic and Mine Sibel Gurun


DOI: 10.2174/1570159X17666191021111809


Review Article

Dysregulation of the gut-brain axis, dysbiosis and influence of numerous factors on gut microbiota associated parkinson’s disease

, 2021; 19(2): 233-247.

Gagandeep Kaur, Tapan Behl*, Simona Bungau, Arun Kumar, Md Sahab Uddin, Vineet Mehta, Gokhan Zengin, Bijo Mathew, Muhammad Ajmal Shah and Sandeep Arora


DOI: 10.2174/1570159X18666200606233050


Review Article

The potential role of dysfunctions in neuron-microglia communication in the pathogenesis of brain disorders

, 2020; 18(5): 408-430.

Katarzyna Chamera, Ewa Trojan, Magdalena Szuster-Głuszczak and Agnieszka Basta-Kaim*


DOI: 10.2174/1570159X17666191113101629


Review Article

Role of oxidative stress and metal toxicity in the progression of Alzheimer’s disease

, 2020; 18(7): 552-562.

Hareram Birla, Tarun Minocha, Gaurav Kumar, Anamika Misra and Sandeep Kumar Singh*


DOI: 10.2174/1570159X18666200122122512


Review Article

An overview of the heterogeneity of major depressive disorder: Current knowledge and future prospective

, 2020; 18(3): 168-187.

Kaipuzha Venu Athira, Sikta Bandopadhyay, Pavan Kumar Samudrala, V.G.M. Naidu, Mangala Lahkar and Sumana Chakravarty*


DOI: 10.2174/1570159X17666191001142934


Review Article

Vasopressin & oxytocin in control of the cardiovascular system: An updated review

, 2020; 18(1): 14-33.

Nina Japundžić-Žigon*, Maja Lozić, Olivera Šarenac and David Murphy


DOI: 10.2174/1570159X17666190717150501



Review Article

Neuroprotective polyphenols: A modulatory action on neurotransmitter pathways

, 2020; 18(5): 431-445.

Elzbieta Rebas, Jowita Rzajew, Tomasz Radzik and Ludmila Zylinska*


DOI: 10.2174/1570159X18666200106155127


Review Article

Current and future neuropharmacological options for the treatment of essential tremor

, 2020; 18(6): 518-537.

Hortensia Alonso-Navarro, Elena García-Martín , José A.G. Agúndez and Félix J. Jiménez-Jiménez*


DOI: 10.2174/1570159X18666200124145743



Review Article

Pharmacological interventions and rehabilitation approach for enhancing brain self-repair and stroke recovery

, 2020; 18(1): 51-64.

Rafał Szelenberger, Joanna Kostka, Joanna Saluk-Bijak and Elżbieta Miller*


DOI: 10.2174/1570159X17666190726104139


Review Article

Current understanding of central nervous system drainage systems: Implications in the context of neurodegenerative diseases

, 2020; 18(11): 1054-1063.

Vladimir N. Nikolenko , Marine V. Oganesyan, Angela D. Vovkogon, Arina T. Nikitina, Ekaterina A. Sozonova, Valentina A. Kudryashova, Negoria A. Rizaeva, Ricardo Cabezas, Marco Avila-Rodriguez, Margarita E. Neganova, Liudmila M. Mikhaleva, Sergey O. Bachurin, Siva G. Somasundaram, Cecil E. Kirkland, Vadim V. Tarasov and Gjumrakch Aliev*


DOI: 10.2174/1570159X17666191113103850



Most Accessed Articles

A Healthy Gut for a Healthy Brain: Preclinical, Clinical and Regulatory Aspects

, 2021; 19(5): 610-628.

Carla Petrella*, Stefano Farioli-Vecchioli, Giusy Ylenia Cisale, Georgios Strimpakos, John Joseph Borg, Mauro Ceccanti, Marco Fiore*, Giovanni Monteleone and Robert Nisticò


DOI: 10.2174/1570159X18666200730111528


Crosstalk between Inflammation and the BBB in Stroke

, 2020; 18(12): 1227-1236.

Yuyou Huang, Shengpan Chen, Yumin Luo* and Ziping Han*


DOI: 10.2174/1570159X18666200620230321




Emerging Evidence for Neuropsycho-Consequences of COVID-19

, 2021; 19(1): 92-96.

Jingwen Li, Xi Long, Qing Zhang, Xi Fang, Fang Fang, Xuefei Lv, Dandan Zhang, Yu Sun, Na Li, Shaoping Hu, Zhicheng Lin* and Nian Xiong*


DOI: 10.2174/1570159X18666200507085335



Current and Future Neuropharmacological Options for the Treatment of Essential Tremor

, 2020; 18(6): 518-537.

Hortensia Alonso-Navarro, Elena García-Martín , José A.G. Agúndez and Félix J. Jiménez-Jiménez*


DOI: 10.2174/1570159X18666200124145743


Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease

, 2021; 19(2): 233-247.

Gagandeep Kaur, Tapan Behl*, Simona Bungau, Arun Kumar, Md. Sahab Uddin, Vineet Mehta, Gokhan Zengin, Bijo Mathew, Muhammad Ajmal Shah and Sandeep Arora


DOI: 10.2174/1570159X18666200606233050




The Effects and Underlying Mechanisms of Cell Therapy on Blood-Brain Barrier Integrity After Ischemic Stroke

, 2020; 18(12): 1213-1226.

Li Gao, Zhenghong Song, Jianhua Mi, Pinpin Hou, Chong Xie, Jianquan Shi, Yansheng Li* and Anatol Manaenko*


DOI: 10.2174/1570159X18666200914162013


The Dawn of Mitophagy: What Do We Know by Now?

, 2021; 19(2): 170-192.

Dmitrii M. Belousov, Elizaveta V. Mikhaylenko, Siva G. Somasundaram, Cecil E. Kirkland* and Gjumrakch Aliev*


DOI: 10.2174/1570159X18666200522202319



Current Understanding of Central Nervous System Drainage Systems: Implications in the Context of Neurodegenerative Diseases

, 2020; 18(11): 1054-1063.

Vladimir N. Nikolenko , Marine V. Oganesyan, Angela D. Vovkogon, Arina T. Nikitina, Ekaterina A. Sozonova, Valentina A. Kudryashova, Negoria A. Rizaeva, Ricardo Cabezas, Marco Avila-Rodriguez, Margarita E. Neganova, Liudmila M. Mikhaleva, Sergey O. Bachurin, Siva G. Somasundaram, Cecil E. Kirkland, Vadim V. Tarasov and Gjumrakch Aliev*


DOI: 10.2174/1570159X17666191113103850


Circadian Rhythm Disruption and Alzheimer’s Disease: The Dynamics of a Vicious Cycle

, 2021; 19(2): 248-264.

Ashish Sharma*, Gautam Sethi, Murtaza M. Tambuwala, Alaa A. A. Aljabali, Dinesh Kumar Chellappan, Kamal Dua and Rohit Goyal*


DOI: 10.2174/1570159X18666200429013041




Editor-in-Chief

graphic
Ferdinando Nicoletti
University Rome"da Sapienza"
Rome
(Italy)
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Journal History

Current Neuropharmacology was introduced in 2003 and Dr. Ferdinando Nicoletti is the New Editor-in-Chief of the journal, appointed in 2019.
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