Medicinal Chemistry

Prof. D. Hadjipavlou-Litina received her Ph.D. in Pharmacy at the Aristotle University of Thessaloniki, Greece under the supervision of Prof. P.N. Kourounakis. She was promoted to full professor in 2009. Her research interests involve synthesis and pharmacochemical studies on anti-inflammatory and antioxidant agents, on inhibitors of enzymes implicated in the inflammation and in the coagulation process in general, as well as the correlation of inflammation with cancer, the theoretical and experimental calculation of physicochemical parameters implicated in biological response, the relationship between structure and activity (use of Computational Chemistry in Drug Design) and analysis and comparative study of Quantitative Structure/Activity Relationships (QSAR) of various categories of drugs and bioactive molecules with the aim of commercially available calculation programs. Her research has resulted in the publication of over 210 peer-reviewed articles, over 5400 citations. She is in the editorial board of 7 journals and the editor in two. She has been awarded by the American Chemical Society twice for most assessed research published papers (Hadjipavlou-Litina D, Garg R, Hansch C. Chem. Rev. 2004, 104(9): 3751-94; Michaelidou AS, Hadjipavlou-Litina D. Chem. Rev. 2005,105(9): 3235-71).