Dr. Shammas is employed as a Lead Scientist in the field of Translational Cancer Research at Harvard (Dana Farber) Cancer Institute, Boston, USA. His research focuses on understanding mechanisms underlying genomic instability and their translational significance in cancer, including Barrett’s esophageal adenocarcinoma. He has developed novel tools/assay systems to study genomic evolution in cancer and has identified key targets and novel drugs to inhibit/reduce genomic evolution, whether intrinsic to cancer cell or that induced/increased by chemotherapeutic agents. These drugs have potential to inhibit tumor growth, overcome/minimize harmful genomic impact of chemotherapy and inhibit/delay progression of cancer to advanced and more aggressive stages. He is a co-author over 60 scientific publications including book chapters and has trained a number of students (undergraduate, graduate), postdoctoral fellows and clinical fellows. He has served and/or serving as Principal Investigator, Co-Principal Investigator and/or Co-investigator on several research grants from the NIH (USA), including R01 grant or even larger grants, including Program Project and Specialized Programs of Research Excellence grants from NIH. He is serving or has served as a Founding Editor, Editor, Lead Guest Editor and/or Guest Associate Editor for several scientific journals, a Grant Reviewer, and as an External Examiner for PhD students for Universities abroad.