Pituitary Stalk Interruption Syndrome in a Newborn with Encephalopathy: A Case Report
Mary J. Jose1, *, Lara M. Leijser1, 3, Anvita Pauranik2, Harish Amin1
1 Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Canada
2 Department of Diagnostic Imaging, Cumming School of Medicine, University of Calgary, Calgary, Canada
3 Alberta Children’s Hospital Research Institute, Calgary, Canada
Pituitary Stalk Interruption Syndrome is a rare midline brain anomaly involving the pituitary gland that leads to a variable degree of pituitary hypofunction with a classic neuroimaging finding of the ectopic posterior pituitary, thin or absent pituitary stalk, and anterior pituitary hypoplasia.
We present the case of a term newborn who developed encephalopathy and respiratory distress during the neonatal period and was later diagnosed with Pituitary Stalk Interruption Syndrome.
Genetic defects have been identified in 5% of cases, and at times there are associated extra pituitary malformations. In spite of being a well-described syndrome, a detailed description of its neonatal presentation and course is lacking in the literature.
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* Address correspondence to this author at the Department of Pediatrics, Section of Neonatology, Cumming School of Medicine, University of Calgary, HMRB room 274; 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada; Tel: (403) 944-4638; E-mail: email@example.com
Abdullah Shehab Emirates Cardiac Society Emirates Medical Association Dubai (United Arab Emirates) Biography
Biography of Abdullah Shehab
Dr. Abdullah Shehab has 22 years of experience in Internal medicine, cardiology and interventional cardiology and medical education. Currently, he serves as the General Secretary of Emirates Cardiac Society and Vice President of Gulf Intervention Society. He is a Fellow of royal college of physicians UK, American college of physician, European society of cardiology, American college of cardiology, American society of cardiac intervention and fellow of the American heart association. Professor Shehab is the Chief Editor of Emirates Medical Journal and also serves as Editor in many other regional and international journals. Dr. Shehab has published 149 paper in Medline. His research interest includes: Heart failure, Coronary artery disease, Dyslipidaemia, Hypertension, Arrhythmias, Cardiac intervention, Cardiac imaging, Screening for cardiac disease in sport players, cardiovascular disease in pregnancy.