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Current Enzyme Inhibition

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Volume 20 , Issues 3, 2024

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Institutional Members

Editorial Board

cei Editor-in-Chief cei_ebm_supuran_001 Supuran Claudiu T. Neurofarba Department University of Florence Florence Italy

CLAUDIU T. SUPURAN is professor of medicinal chemistry at the Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, University of Florence, Italy. He has published more than 1250 papers, his Hirsch factor is h = 110; the number of citations since 1995 > 49800. His main research interest is on enzyme inhibitors, and especially carbonic anhydrase inhibitors, of which he discovered several new classes in the last years. One of the sulfonamides discovered in his group entered Phase I clinical trials in 2014 for the treatment of advanced, metastatic solid tumors. He is Editor-in-Chief of Expert Opinion on Therapeutic Patents, Journal of Enzyme Inhibition and Medicinal Chemistry, Current Enzyme Inhibition, etc. For the last 25 years the main interest of his research was focused on metallo-enzymes and their modulators of activity. In 2013 he was rated as the most cited scientists in Pharmacology & Toxicology by LabTimes (LabTimes 2013, 5, 38). Orcid Scopus RsearcherId
Co-Editor-in-Chief cei_ebm_litina_001 Hadjipavlou-Litina Dimitra Department of Pharmaceutical Chemistry, School of Pharmacy Aristotle University of Thessaloniki Thessaloniki Greece

Professor Dimitra Hadjipavlou-Litina received her undergraduate training in Pharmacy at Aristotle University of Thessaloniki, Greece (1975-1979) and her PhD in Pharmacy at the same University. She conducted postdoctoral studies at California (supervisor Professor Corwin Hansch). Currently she is a full professor and a head at the School of Pharmacy.

Her research interests involve synthesis and biological studies and the use of Computational Chemistry in Drug Design and resulted in the publication of over 220 peer-reviewed articles over 5000 citations and h factor = 38. Currently is the Editor of this journal (Current Enzyme Inbibition, CEI), published by Bentham Science Publishers. Scopus RsearcherId
Associate Editors cei_ebm_alfeafy_001 Alafeefy Ahmed M. Chemistry Department Prince Sattam Bin Abdulaziz University Al-Kharj Saudia Arabia

Dr. Ahmed M Alafeefy got his PhD, Pharmaceutical Chemistry, in 2005 from Egypt and left for Saudi Arabia. His current research interest covers the development of potential drugs to combat cancer and viral diseases. He has been consistently working to locate biochemical rationale which enables the preparation of antitumor drugs focusing on qualitative differences between normal and cancerous cells. The complementary development of semisynthetic biologically active small molecules as antiviral, anticancer agents is his future aim. Currently, he is an Assoc. Prof. of Pharmaceutical Chemistry Kulliyyah of Science, IIUM, Malaysia. He has published more than 40 papers in reputed journals. Scopus RsearcherId
cei_ebm_marc-lies_001 Ilies Marc A. Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research Temple University Philadelphia PA USA

Dr. Marc A. Ilies was born and educated in Romania, and received his PhD in 2001 with Professor Alexandru T. Balaban from C. D. Nenitzescu’s Department of Organic Chemistry of Polytechnic University of Bucharest. After post-doctoral studies from Texas A&M University and University of Pennsylvania, he joined the Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, where he is currently an Associate Professor and an affiliated member of Moulder Center for Drug Discovery Research. His research interests fit within the broadly-defined medicinal chemistry/chemical biology of membrane interfaces, being focused on the development of chemical solutions for the efficient and selective delivery of drugs and nucleic acids for therapeutic purposes. Scopus RsearcherId
Regional Editor Europe cei_ebm_costa_001 Costa Giosuè Department of Health Science Magna Græcia University Catanzaro Italy

Dr. Giosuè Costa obtained a degree in “Pharmacy” with full marks in 2008 from the University "Magna Græcia" of Catanzaro. Then he followed the three- year doctorate in Pharmaceutical Sciences, continuing his research activity in the field of interactions between bio-molecules by innovative molecular modeling tools. In 2012, at the same University, he obtained the Ph.D. in Pharmaceutical Sciences, discussing a thesis entitled "Computational studies applied to HIV-1 macromolecular targets and implications in rational drug design of new selective antiviral agents". Dr. Giosuè Costa collaborates with several foreign departments. Currently, he is a Postdoctoral Researcher at the Department of Health Science of “Magna Graecia” University of Catanzaro (Italy) with H-index= 18 (Scopus) and no. of citations = 810 (Scopus). His scientific interests concern the application of new computational algorithms, and in particular Virtual Screening techniques, for the study of intermolecular drug-receptor interactions and the design of potential antitumoral, antiviral, analgesic and antidepressant drugs. In the nutraceutical field, his interest is mainly in the identification of potential therapeutic activities in natural products contained in foods. Furthermore, in the field of drug discovery, he studies the "repositioning" for other therapeutic indications (or rationalizing some side effects) of drugs previously approved by the FDA. Orcid Scopus RsearcherId
Frontiers Section Editor(s) cei_ebm_carta_001 Carta Fabrizio Neurofarba Department University of Florence Florence Italy

Dr. Fabrizio Carta received his degree in 2002 in Pharmaceutical Chemistry and Technology from the University of Sassari (IT). In 2008 he received his Ph.D. in Chemistry at the School of Chemistry of the Bristol University (UK), he was appointed as a postdoctoral fellow at MIT (USA) and finally joined Prof. Scozzafava’s and Supuran’s groups at the University of Florence (IT). Among others, he is an Editorial Board Member of the Journal of Enzyme Inhibition and Medicinal Chemistry (JEIMC) and Journal of the Turkish Chemical Society, Section A: Chemistry (JOTCSA). He is co-author of 100 publications on peer-reviewed international journals, 3 book chapters and 4 patents. Pharmaceutical Chemistry Orcid Scopus RsearcherId
cpc_ebm_poli-g_001 Poli Giulio Department of Pharmacy University of Pisa Pisa Italy

Dr. Giulio Poli obtained his MD in Medicinal Chemistry and his PhD in Science of Drug and Bioactive Substances from the Department of Pharmacy, University of Pisa (Italy). Currently, he is an untenured assistant professor in Medicinal Chemistry at the Department of Pharmacy, University of Pisa (Italy). His research activity at the Molecular Modeling and Virtual Screening Laboratory mainly focuses on the development of efficient virtual screening protocols and innovative computational procedures for the identification of hit/lead compounds of various protein targets, as well as on lead and hit-to-lead optimization studies. Drug and Bioactive Substances Orcid Scopus RsearcherId
Editorial Board Members cei_ebm_akdemir_001 Akdemir Atilla Department of Pharmacology Bezmialem Vakif University Istanbul Turkey

Dr. Akdemir obtained his PhD and MSc from the Department of Pharmaceutical Sciences (VU University Amsterdam, The Netherlands). His research interests are mainly molecular modelling and molecular pharmacology studies of various drug targets (including carbonic anhydrases and nicotinic acetylcholine receptors). He is currently associate professor of pharmacology and vice-dean at the Faculty of Pharmacy (Bezmialem Vakif University, Istanbul, Turkey). Orcid Scopus RsearcherId
cei_ebm_othman_001 ALOthman Zeid A. Chemistry Department, College of Science King Saud University Riyadh Saudi Arabia

Zeid A. ALOthman, Professor of Chemistry, at Chemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia. He obtained his Ph.D. in chemistry at Oklahoma State University in 2006.

He is working on a variety of topics ranging from the high surface area materials, Water treatment and production, Ion exchanger, separation and Environmental studies.

He is the group leader of Advanced Materials and Chromatography Group and the supervisor of the Advanced Materials Research Chair.

He supervised seven PhD students and more than 12 master students.

He is an author and co-author of more than 350 scientific publications, three books and six patents. Orcid Scopus RsearcherId
cei_ebm_barreca-d_001 Barreca Davide Dipartimento di Scienze Chimiche, biologiche, farmaceutiche ed ambientali Università di Messina Messina Italy

Davide Barreca is an Assistant Professor of biochemistry at the University of Messina. He is specialized in enzyme modulation by natural compounds, inhibition of protein aggregation and analysis of enzymatic pattern. Most of his research projects concentrate on separation and identification of unknown flavonoids, structural-activity elucidation, and biochemical analysis of their health promoting or cytotoxicity properties on cells culture, exploring their suitable employment in pharmaceutical as well as nutraceutical food supplements. He is author of 86 papers in peer-reviewed journals, 30 chapters in books, and 70 conference proceedings, reviewer of over 40 international scientific journals, and evaluator of research. Orcid Scopus RsearcherId
cei_ebm_Bonardi_001 Bonardi Alessandro Neurofarba Department University of Florence Florence Italy Orcid Scopus RsearcherId cei_ebm_cai-s-ah_001 Cai Shuowei Department of Chemistry and Biochemistry University of Massachusetts Dartmouth Dartmouth MA USA

Dr. Shuowei Cai is currently a Professor at the Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth. He did M.S. in Analytical Chemistry from Nankai Univerity, Tianjin, P. R. China in 1993 and M.S. in Chemistry from University of Massachusetts Dartmouth, Dartmouth, MA in 1998. Later, he obtained a PhD in Biological Chemistry from University of Massachusetts Amherst, Amherst, MA in 2001. Scopus RsearcherId
cei_ebm_cappasso_001 Capasso Clemente Department of Biology, Agriculture and Food Science – CNR Institute of Bioscience and Bioresources (IBBR) Piazzale Aldo Moro Rome Italy

Dr. Clemente Capasso is a researcher at the National Research Council. His research interest from 1992 to date has been the study of the structure/function relationship of both native and recombinant proteins from terrestrial, marine organisms and pathogenic microorganisms. This allowed him to acquire extensive knowledge of most protein purification procedures as well as kinetic, chemical–physical and structural characterization of enzymes. He has written 13 book chapters and published over 100 papers. He acquired an intense training in Italian and international laboratories. He is the Associate Editor of Journal of Enzyme Inhibition and Medicinal Chemistry, and is in the Editorial Board of the journal Expert Opinion on Therapeutic Patents. Orcid Scopus RsearcherId
cei_ebm_ferraroni-m_001 Ferraroni Marta Department of Chemistry University of Florence Sesto Fiorentino Italy

Dr. Marta Ferraroni obtained her degree and her PhD in Chemistry from the University of Florence, Italy. Currently, she is a researcher at the Department of Chemistry, University of Florence. The activity of Dr. Ferraroni is primarily focused on the field of Bioinorganic and Medicinal Chemistry, and its aim is the comprehension of the structure-activity relationships of metalloenzymes involved in relevant processes. Dr. Ferraroni is a co-author of 55 scientific articles and of 3 chapters of books edited by international publishing companies. Orcid Scopus RsearcherId
cei_ebm_Giovannuzzi_001 Giovannuzzi Simone Neurofarba Department University of Florence Florence Italy Orcid Scopus RsearcherId cei_ebm_glucin_001 Glucin Ilhami Department of Chemistry Ataturk University Erzurum Turkey

Prof. Dr. İlhami GÜLÇİN obtained a doctorate (Ph.D.) in Chemistry from the Ataturk University of Erzurum, Turkey. He is the member of Turkish Academy of Sciences (TÜBA). He has experience in the research of enzyme purification, enzyme inhibition, antioxidant activity, and biological activities. He has also published more than 200 scientific publications. His manuscripts have more than 9000 citations. Orcid Scopus RsearcherId
cei_ebm_karioti-a_001 Karioti Anastasia Department of Pharmacy Aristotle University Thessaloniki Greece

A. Karioti is Assistant Professor at the Dept. of Pharmaceutical Sciences, Aristotle University of Thessaloniki, Greece, has a Ph.D. in Pharmacognosy of Bioactive Natural Products from the University of Athens, Greece. She served for eight years as Teaching and Research Assistant in Univ. of Florence, Italy (2007-2014). In general the main research lines are Isolation and structural identification of a wide range of natural constituents (both phenols and terpenoids), Pharmacological evalution of extracts and purified constituents and Development of analytical methods for the quality control of herbal medicinal plants and preparations and products thereof. She is author of 77 publications, h-index 19 (google scholar). Orcid Scopus RsearcherId
cei_ebm_mori_001 Mori Mattia Department of Biotechnology, Chemistry & Pharmacy University of Siena Italian Institute of Technology Roma Italy

Dr. Mattia Mori obtained his degree in Medicinal Chemistry and his PhD in Structural Biology from the University of Florence, Italy. Currently, he is a researcher at the Center for Life Nano Science at Sapienza of the Istituto Italiano di Tecnologia (IIT) in Roma, Italy. The research activity of Dr. Mori focuses on medicinal chemistry and drug discovery, with a particular dedication to the use of computer simulations to discover and develop bioactive small molecules, or to study the conformational space of target proteins. Dr. Mori is a co-author of more than 45 papers and 1 patent. Orcid Scopus RsearcherId
cei_ebm_poirier_001 Poirier Donald Department of Molecular Medicine Faculty of Medicine CHUQ and Universite Laval Quebec City QC Canada

Dr. Donald Poirier received his basic training in organic chemistry (PhD at Université Laval, 1980-1985) and subsequently specialized in medicinal chemistry and endocrinology (Post-doctorat at CHUL - Research Center, 1986-1990). Professor at Université Laval since 1991, he is especially interested in the development of inhibitors of steroidogenic enzymes (steroid sulfatase and 17β-HSDs types 1, 2, 3, 7 and 12) and antitumor agents for the treatment of different diseases (breast, prostate and leukemia cancers, endometriosis, osteoporosis and Alzheimer). He is also interested to additional aspects of organic chemistry (synthesis, solid-phase synthesis, new methodologies, NMR analysis, etc.) and medicinal chemistry (SAR and QSAR analysis, molecular modeling, biological assays, etc.). He has published 204 scientific publications and 9 patent applications. Scopus RsearcherId
cei_ebm_shalini_001 Singh Shalini Department of Chemistry Bareilly College Bareilly India

Dr. Shalini Singh is presently working as an Assistant Professor in the Department of Chemistry, Bareilly College, Bareilly (U.P.) India. She holds a Ph.D. from A.P.S. University Rewa, (M.P). She has got awards and rewards of an unending sequence like Recipient of D.S.T. Women Scientist Scheme Award (WOS-A), U.G.C. Research Awardee 2011, Recipient of Indian Chemical Society Award-2012 Dr. Singh has contributed 42 research papers of repute in high impact factor Journals. Dr. Singh is a fellow member of Indian Chemical Society Kolkatta, India. Dr Singh is also a member of many prestigious Editorials boards of national and international reputed journals like Journal of Enzyme Inhibition and Medicinal Chemistry. Scopus RsearcherId
cei_ebm_sogorb_001 Sogorb Miguel A. Instituto de Bioingenieria, Unidad de Toxicologia y Seguridad Quimica University Miguel Hernández Elche Spain

Dr. Sogorb is a Faculty Professor of Toxicology at Miguel Hernández University (Spain). He started his research career in biochemical Toxicology with the characterization of enzymes involved in the detoxication of organophosphorus insecticides. At the same time, he was involved in the characterization of Neuropathy Target Esterase (an esterase target of organophosphorus insecticides) in in vitro cellular models. Dr. Sogorb performed a postdoctoral stay (2 years) at the Texas A&M University where he was involved in the generation and characterization of mutant bacterial phosphotriesterases by site-directed mutagenesis for enhancing and modulating their catalytic efficacy. He has 59 papers in peer-reviewed journals and 8 book chapters. Orcid Scopus RsearcherId
cei_ebm_sebastian_001 Thibaudeau Sébastien Chemistry Department University of Poitiers Poitiers France

Sébastien Thibaudeau is a professor of organic chemistry at the University of Poitiers. He completed his MD and PhD in Poitiers (France) and a fellowship at the chemistry department in Oxford University (UK). He is head of the superacid group in the organic synthesis team at the Institute of Chemistry of Poitiers (IC2MP). His current research is mainly focused on the use of superacid activation in organic and bio-organic chemistry. Orcid Scopus RsearcherId
cei_ebm_vullo_001 Vullo Daniela Department of Chemistry University of Florence Florence Italy

Dr. Daniela Vullo obtained her Ph.D. in Chemistry at the University of Florence, Italy. Currently, she has a post-doc position at the same university, Department of Chemistry “Ugo Shiff” under the supervision of Prof. Andrea Scozzafava and Prof. Claudiu T. Supuran. The scientific research is focused on enzyme activity characterization, mainly carbonic anhydrase inhibitors and activators and resulted in the publication of over 280 papers with Hirsch factor h=51 and 9112 citations. Orcid Scopus RsearcherId
Associate Editorial Board Member(s) cpc_ebm_nocentini-sh_001 Nocentini Alessio Department of Neurofarba University of Florence Florence Italy

Alessio Nocentini, PhD obtained his MSc in Medicinal Chemistry and Technologies in 2014 and the PhD in medicinal chemistry at the University of Florence (Italy), where he now works as a post-doc researcher. He was awarded with the best PhD thesis Prize 2018 by the Medicinal Chemistry Division of the Italian Chemical Society. His research activity is mainly focused on the in silico design and synthesis of Carbonic Anhydrases modulators and their kinetic and biological characterization. He is author of over 40 publications in peer-reviewed scientific journals with a high impact factor and a considerable number of contributions in conference proceedings (Scopus H-index: 13; number of citations: 364). Orcid Scopus RsearcherId
cei_ebm_Thatoi-hn-sa_001 Thatoi Hrudayanath Department of Biotechnology North Orissa University Odisha India

Dr. H.N. Thatoi, is a Professor, Department of Biotechnology, North Orissa University, Odisha, India and is also presently working as Director of Centre for Similipal Studies North Orissa University. He obtained his M. Sc, M. Phil. and Ph. D. degree from Utkal University, Odisha, and has more than 15 years of teaching and 25 years of research experience. He has contributed immensely to the field of Microbiology and Biotechnology throughout his research and teaching career and his research activities are mainly focused on exploration microbial diversity, bioremediation, biofuel production, mangrove biology, bioactivity studies in medicinal plants and mushrooms, ethno-pharmacology and biocomputational studies such as in silico drug design, molecular docking, modeling and protein dynamism etc. His publication record is impressive with more than 200 research papers published in various national and international journals and 30 book chapters. Prof. Thatoi has also authored two text books and 15 reference books published by reputed national and international publishers. Orcid Scopus RsearcherId
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