Management of malignant pleural mesothelioma is still a clinical challenge.
Currently, the best survival figures are described after multimodality regimen including
macroscopic complete resection achieved by either extrapleural pneumonectomy or
extended pleurectomy/decortication in patients selected for tumor biology, stage, and
risk factors. One particular approach is to perform neoadjuvant chemotherapy followed
by macroscopic complete resection, which will be discussed in the following chapter.
Keywords: Extrapleural pneumonectomy, neoadjuvant chemotherapy,
pleurectomy/decortication, thoracic surgery.
