This chapter presents a critical overview of the relationship which transplant medicine has had with the market as a source of organs for transplantation. It has three parts. The first two parts discuss the increasing appeal of the market option in practice and theory against the backdrop of the worsening organ crisis and the intensification of pro-transplant interests. The emerging trend suggests that the recent achievements in the struggle against international organ trafficking do not herald the abolition of the organ market but rather presage its reconfiguration in deglobalized, more or less regulated, forms. The third part rephrases the market question. It concludes that the struggle against a market in organs could make sense, let alone stand a chance, only as part of a general struggle against the conditions that have made it so appealing in the first place.