Inflammation and oxidative stress are synergistic partners in the
etiopathogenesis of diverse diseases. Polyphenols, such as anthocyanins, are
responsible for the regulation of the inflammatory process and activation of the
endogenous antioxidant defense system. Anthocyanins modulate the level of
inflammatory markers and exert an anti-inflammatory effect. Consequently, translating
the research outcomes into clinical practice significantly contributes to the prevention
and management of chronic diseases. The chapter summarizes the role of anthocyanins
as anti-inflammatory and anti-oxidative molecules in both health and diseases.
Anthocyanins downregulate pro-inflammatory markers in chronic disease and thus
suppress inflammation as well as oxidative stress in inflammatory disorders. The
chapter can help researchers and other healthcare professionals to understand the
importance of anthocyanin use in chronic diseases.
Keywords: Biomarkers, Inflammation, Inflammatory mediators, Oxidative stress, Polyphenols.