Phyto-nanotechnology presents a promising avenue for revolutionizing
rheumatoid arthritis (RA) treatment. By integrating plant-derived compounds with
nanotechnology, this approach addresses the limitations of conventional RA therapies.
Nanoformulations of phytochemicals, such as curcumin, resveratrol, and quercetin,
enable targeted drug delivery to inflamed joints, optimizing therapeutic efficacy while
minimizing systemic side effects. Enhanced bioavailability, attributed to the
encapsulation of phytochemicals within nanoparticles, facilitates improved
pharmacokinetics and delivery across biological barriers. The immunomodulatory and
anti-inflammatory properties of phytochemicals are harnessed more effectively through
nanoparticle-mediated sustained release, offering the potential to suppress
inflammatory processes and mitigate joint damage. Furthermore, the cartilageprotective and regenerative capabilities of certain plant-derived compounds can be
optimized with nanotechnology, promoting joint health. The versatility of phytonanotechnology allows for combination therapies, synergizing the benefits of multiple
compounds and conventional drugs within nanoparticles. While these advancements
hold substantial promise, further research is imperative to refine nanoparticle
formulations, assess safety, and validate efficacy through preclinical and clinical
studies, ultimately paving the way for transformative RA treatments in clinical practice.
In this chapter, phyto-nano drug delivery systems that can increase the effectiveness of
medicinal plants in RA treatment are focused on.
Keywords: Green synthesis, Herbal medicine, Modern drug delivery systems, Nanoparticles, Nanocarriers, Phyto-nanotechnology, Rheumatoid arthritis, Traditional medicine.
