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Medical Applications of Beta-Glucan

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Beta Glucan Against Coronavirus

Author(s): Betül Gürünlü

Pp: 26-34 (9)

DOI: 10.2174/9789815039238122010005

* (Excluding Mailing and Handling)

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new
virus that is the source of COVID-19 pandemic and causing great damage all over the
world. Among the main accelerating factors of mortality due to COVID-19 are the
direct endothelial damage caused by coronaviruses and the defect in the clotting
mechanism due to the cytokine storm. These two main destructive factors are deeply
related the dysregulation of the immune system. The comorbidities and ethnic
variations are also effecting the risk of associated thrombogenic disruption. Beta
glucans are gathering a wide range of attention due to their immunostimulating effect,
drug potential, and biologically active nature against many diseases by boosting the
immune system. In this review, the healing and positive effect of the biological
response modifier, beta glucan, on COVID-19’s symptoms such as cytokine storm,
coagulopathy, lung inflammation causing mortality by modulating the immune system
are discussed.

Keywords: Beta Glucan, Coronavirus, COVID-19, Immune System.

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