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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

An Overview of Synthesis of Indole Alkaloids and Biological Activities of Secondary Metabolites Isolated from Hyrtios Species

Author(s): M. Novanna, K.R. Ethiraj and S. Kannadasan*

Volume 19, Issue 3, 2019

Page: [194 - 205] Pages: 12

DOI: 10.2174/1389557518666181102110537

Price: $65


Marine sponges are a rich source of more than 50% of marine natural compounds that have been isolated from marine organisms. This review article is focused on the importance of biologically active and pharmaceutically important secondary metabolites extracted from one of the important classes of marine sponge Hyrtios sp. This review also deals with reported synthetic routes of some indole alkaloids extracted from the marine sponge Hyrtios sp. A range of bioactivities displayed by indole-based alkaloids is described.

Keywords: Hyrtios sp., marine sponges, indole alkaloids, Hyrtinadine A, Hyrtiosin B, Asperazine.

Graphical Abstract
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