Title: Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists
Volume: 5
Issue: 3
Author(s): Brad O. Buckman, Ameen Ghannam, Angela Li, Meina Liang, Raju Mohan and Howard P. Ng
Affiliation:
Keywords:
solid-phase synthesis, ccri receptor antagonist
Abstract: An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).