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Current Medicinal Chemistry

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Review Article

Recent Advances in Lanthanide Based Nano-Architectures as Probes for Ultra High-Field Magnetic Resonance Imaging

Author(s): Silvanose Biju and Tatjana N. Parac-Vogt*

Volume 27, Issue 3, 2020

Page: [352 - 361] Pages: 10

DOI: 10.2174/0929867325666180201110244

Price: $65

Abstract

Paramagnetic Lanthanide ions incorporated into nano- architectures are emerging as a versatile platform for Magnetic Resonance Imaging (MRI) contrast agents due to their strong contrast enhancement effects combined with the platform capability to include multiple imaging modalities. This short review examines the application of lanthanide based nanoarchitectures (nanoparticles and nano- assemblies) in the development of multifunctional probes for single and multimodal imaging involving high field MRI as one imaging modality.

Keywords: Magnetic resonance imaging, lanthanide oxide nanoparticles, lanthanide fluoride nanoparticle, upconversion nanoparticle, micelles, bimodal MRI imaging, ultra-high field MRI.

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