摘要
SUMU化修饰是可逆的翻译后修饰，能够结合小肽SUMO（小泛素样修饰）到靶向蛋白上。所有蛋白质在SUMO化修饰上的通路上的SUMO化修饰和SUMO化化合物的表达近期发现于组织衰退过程。此外，控制细胞衰老的关键因素是SUMO化修饰。本文对目前细胞衰老的SUMU化修饰的功能信息进行综述。
关键词: SUMO化修饰，P53，RB，衰老，老化
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