Abstract
The high-throughput screening core at the University of Minnesota is part of the Institute for Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development center. The Institute provides scientific services to both academic and business communities and supports translational medicine via collaborations and contractual work. The ITDD is well-known for its broad range of screening capabilities and offers extensive medicinal chemistry expertise along with GMP scale-up and pre-clinical pharmacology support.
Keywords: Drug development, drug discovery, good manufacturing practices (GMP), high throughput screening (HTS), medicinal chemistry, pharmacology, scale-up, translational science.
Combinatorial Chemistry & High Throughput Screening
Title:From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota
Volume: 17 Issue: 3
Author(s): Peter I. Dosa, Gunda I. Georg, Vadim J. Gurvich, Jon E. Hawkinson, Michael A. Walters and Henry L. Wong
Affiliation:
Keywords: Drug development, drug discovery, good manufacturing practices (GMP), high throughput screening (HTS), medicinal chemistry, pharmacology, scale-up, translational science.
Abstract: The high-throughput screening core at the University of Minnesota is part of the Institute for Therapeutics Discovery and Development (ITDD), a comprehensive drug discovery and development center. The Institute provides scientific services to both academic and business communities and supports translational medicine via collaborations and contractual work. The ITDD is well-known for its broad range of screening capabilities and offers extensive medicinal chemistry expertise along with GMP scale-up and pre-clinical pharmacology support.
Export Options
About this article
Cite this article as:
Dosa I. Peter, Georg I. Gunda, Gurvich J. Vadim, Hawkinson E. Jon, Walters A. Michael and Wong L. Henry, From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota, Combinatorial Chemistry & High Throughput Screening 2014; 17 (3) . https://dx.doi.org/10.2174/1386207317666140109122033
DOI https://dx.doi.org/10.2174/1386207317666140109122033 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
Call for Papers in Thematic Issues
Artificial Intelligence Methods for Biomedical, Biochemical and Bioinformatics Problems
Recently, a large number of technologies based on artificial intelligence have been developed and applied to solve a diverse range of problems in the areas of biomedical, biochemical and bioinformatics problems. By utilizing powerful computing resources and massive amounts of data, methods based on artificial intelligence can significantly improve the ...read more
Eco-friendly Agents for Biological Control of Pathogenic Diseases
The discovery of an alternative biological approach to disease management includes work on medicinal products derived from natural sources as a starting point for the development of eco-friendly agents for these diseases and the injuries they cause, as well as reducing human contact with hazardous chemicals and their residues. We ...read more
Emerging trends in diseases mechanisms, noble drug targets and therapeutic strategies: focus on immunological and inflammatory disorders
Recently infectious and inflammatory diseases have been a key concern worldwide due to tremendous morbidity and mortality world Wide. Recent, nCOVID-9 pandemic is a good example for the emerging infectious disease outbreak. The world is facing many emerging and re-emerging diseases out breaks at present however, there is huge lack ...read more
Exploring Spectral Graph Theory in Combinatorial Chemistry
Scope of the Thematic Issue: Combinatorial chemistry involves the synthesis and analysis of a large number of diverse compounds simultaneously. Traditional methods rely on brute force experimentation, which can be time-consuming and resource-intensive. Spectral Graph Theory, a branch of mathematics dealing with the properties of graphs in relation to the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Advances in Minimal Access Surgery for Infants and Children
Current Pediatric Reviews Binaphthyl-Derived Mono-, Bi- and Multi-Functional Lewis and Brønsted Base Organocatalysts: A New Vista for Asymmetric Synthesis
Current Organic Chemistry Therapies of Hematological Malignancies: An Overview of the Potential Targets and Their Inhibitors
Current Chemical Biology Therapies for Hepatitis C Infection: Targeting the Non-Structural Proteins of HCV
Current Medicinal Chemistry - Anti-Infective Agents Usefulness of High-Resolution Computed Tomography in Early Diagnosis of Patients with Suspected COVID-19
Current Medical Imaging Melanocortins As Innovative Drugs for Ischemic Diseases and Neurodegenerative Disorders: Established Data and Perspectives
Current Medicinal Chemistry Discovery of Inhibitors of Protein-Protein Interactions from Combinatorial Libraries
Current Topics in Medicinal Chemistry Recent Advances in Synthesis of PAR Ligands as Therapeutic Strategy for Inflammatory Diseases
Mini-Reviews in Medicinal Chemistry Heat Shock Proteins as Prognostic Markers of Cancer
Current Cancer Drug Targets Editorial [ Hot Topic: DPP-IV as a Target in Medicinal Chemistry and Drug Discovery (Guest Editor: Dr. Jens-Uwe Peters) ]
Current Topics in Medicinal Chemistry Self-Protection of Medical Workers in Traditional Hospitals and Clinics Against SARS-CoV-2 Infection
Coronaviruses A Brief Review on Software Implementations and Algorithm Enhancements of Chou’s Pseudo-Amino Acid Compositions
Current Proteomics The Role of Angiotensin-Converting Enzyme in Immunity: Shedding Light on Experimental Findings
Endocrine, Metabolic & Immune Disorders - Drug Targets Novel Hybrid Anticonvulsants Derived from Pyrrolidine-2,5-dione Scaffold with Broad Spectrum of Activity in the Preclinical Studies
Current Topics in Medicinal Chemistry Rheumatologic Aspects of the COVID-19 Pandemic: A Practical Resource for Physicians in Kuwait and the Gulf region as Recommended by the Kuwait Association of Rheumatology
Current Rheumatology Reviews Does Metformin Satisfy as an Option for Host-Directed Therapy in COVID-19?
Anti-Infective Agents Vascular and Parenchymal Mechanisms in Multiple Drug Resistance: a Lesson from Human Epilepsy
Current Drug Targets FDG-PET Scan in Sarcoidosis: Clinical and Imaging Indications
Current Medical Imaging Insights into Immunophilin Structure and Function
Current Medicinal Chemistry Novel Anti-Inflammatory and Neuroprotective Agents for Parkinsons Disease
CNS & Neurological Disorders - Drug Targets