Abstract
The toxicity to cells and animals of type 1 and toxic and non-toxic type 2 Ribosome-Inactivating Proteins (RIP) is discussed in correlation with their catalytic activity, resulting in ribosome inactivation and apoptosis. The symptoms and histopathological lesions induced by RIP to animals and humans is also reviewed.
Keywords: cytotoxicity, toxicity to animals, toxicity to humans, type 1 ribosome-inactivating proteins, toxic type 2 ribosome-inactivating proteins, non-toxic type 2 ribosome-inactivating proteins
Mini-Reviews in Medicinal Chemistry
Title: Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins
Volume: 4 Issue: 5
Author(s): Maria Giulia Battelli
Affiliation:
Keywords: cytotoxicity, toxicity to animals, toxicity to humans, type 1 ribosome-inactivating proteins, toxic type 2 ribosome-inactivating proteins, non-toxic type 2 ribosome-inactivating proteins
Abstract: The toxicity to cells and animals of type 1 and toxic and non-toxic type 2 Ribosome-Inactivating Proteins (RIP) is discussed in correlation with their catalytic activity, resulting in ribosome inactivation and apoptosis. The symptoms and histopathological lesions induced by RIP to animals and humans is also reviewed.
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Cite this article as:
Battelli Giulia Maria, Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins, Mini-Reviews in Medicinal Chemistry 2004; 4 (5) . https://dx.doi.org/10.2174/1389557043403819
DOI https://dx.doi.org/10.2174/1389557043403819 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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