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Abstract
Diabetic retinopathy (DR) is a microvascular disease affecting the eyes of diabetic patients, and is the most prevalent complication of diabetes mellitus. Vision improvement is not possible in the majority of DR patients. Several studies have indicated that microvascular changes, inflammation, oxidative stress, and retinal neurodegeneration are involved in the pathogenesis of DR. Therefore, there is an urgent need for the development of new and effective treatment for DR. Understanding the molecular mechanisms involved in the pathogenesis of disease will pave a way for better treatment and management of DR. This article has emphasized the molecular pathogenesis and treatment of DR.
Keywords: Diabetic Retinopathy, Pre-proliferative diabetic retinopathy, Proliferative diabetic retinopathy, Retinopathy
Current Diabetes Reviews
Title:Diabetic Retinopathy - Pathophysiology to Treatment: A Review
Volume: 20
Author(s): Randhir Dahiya, Aditya Walia, Jasleen Kaur, Praveen Kumar, Inderjeet Verma and Nidhi Rani*
Affiliation:
- Chitkara College of Pharmacy, Chitkara University, Punjab, India
Keywords: Diabetic Retinopathy, Pre-proliferative diabetic retinopathy, Proliferative diabetic retinopathy, Retinopathy
Abstract: Diabetic retinopathy (DR) is a microvascular disease affecting the eyes of diabetic patients, and is the most prevalent complication of diabetes mellitus. Vision improvement is not possible in the majority of DR patients. Several studies have indicated that microvascular changes, inflammation, oxidative stress, and retinal neurodegeneration are involved in the pathogenesis of DR. Therefore, there is an urgent need for the development of new and effective treatment for DR. Understanding the molecular mechanisms involved in the pathogenesis of disease will pave a way for better treatment and management of DR. This article has emphasized the molecular pathogenesis and treatment of DR.
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Cite this article as:
Dahiya Randhir, Walia Aditya, Kaur Jasleen, Kumar Praveen, Verma Inderjeet and Rani Nidhi*, Diabetic Retinopathy - Pathophysiology to Treatment: A Review, Current Diabetes Reviews 2024; 20 () : e220124225930 . https://dx.doi.org/10.2174/0115733998259940231105200251
DOI https://dx.doi.org/10.2174/0115733998259940231105200251 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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