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Current Stem Cell Research & Therapy

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ISSN (Print): 1574-888X
ISSN (Online): 2212-3946

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Review Article

Progress of Cancer Stem Cells in Retinoblastoma

Author(s): Nan Wang and Jian-Min Ma*

Volume 19, Issue 8, 2024

Published on: 06 October, 2023

Page: [1093 - 1101] Pages: 9

DOI: 10.2174/011574888X252989230921065809

Price: $65

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Abstract

The theory of cancer stem cells is a breakthrough discovery that offers exciting possibilities for comprehending the biological behavior of tumors. More and more evidence suggests that retinoblastoma cancer stem cells promote tumor growth and are likely to be the origin of tumor formation, drug resistance, recurrence, and metastasis. At present, some progress has been made in the verification, biological behavior, and drug resistance mechanism of retinoblastoma cancer stem cells. This article aims to review the relevant research and explore future development direction.

Keywords: Retinoblastoma, cancer stem cells, drug resistance, Wnt pathway, targeted therapy, tumor.

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