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Current Functional Foods

Editor-in-Chief

ISSN (Print): 2666-8629
ISSN (Online): 2666-8637

Review Article

Hand-in-glove Effect of Piperine in Anti-cancer Formulations

Author(s): Jatin Kumar, Priyanka Kriplani* and Kumar Guarve

Volume 2, Issue 2, 2024

Published on: 25 September, 2023

Article ID: e270723219193 Pages: 17

DOI: 10.2174/2666862901666230727104158

Price: $65

Abstract

Background: Piperine, an active constituent isolated from Piper nigrum, Piper chaba, Piper sarmentosum, Piper guineense and Piper longum which is used to cure a variety of ailments related to lung, stomach, colon, skin etc. like Alzheimer’s, Parkinson’s disease, ulcerative colitis, cancer, arthritis, inflammatory bowel diseases, diabetes etc.

Objective: The objective of the review is to study the synergistic effect of piperine specially in cancer.

Methods: Patents and current literature mainly emphasizing the synergistic effect of piperine along with other drugs, especially anticancer drugs was reviewed keeping in mind the scientific novelty and impact.

Results: Several synergistic combinations of piperine were explored which can be beneficial for the pharmaceutical industry.

Conclusion: This review will assist the researchers in the preparation of novel formulations with improved efficacy cutting the cost of developing new drug molecules.

Keywords: Bioavailability enhancer, piperine, cancer, combination, molecular targets, synergism.


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