An Overview of Paclitaxel and Molecular Imprinted Polymers Capped
with Quantum Dots as an Alternative Approach for Paclitaxel Extraction
and Detection

Azad   Qayoom   Malik; Tahir ul Gani      Mir; Deepak      Kumar
Abstract

Paclitaxel (Taxol) is a drug that belongs to the class of compounds called Taxane. It is a strong and potent chemotherapeutic drug that inhibits the growth of certain types of cancer cells; however, its abundance is very low, and various types of methodologies have been implemented to extract paclitaxel from the bark of different plants and herbs. The molecularly imprinted polymers (MIPs) could be the best alternative to purify the paclitaxel molecule. MIPs have become an attractive solution for the selective and fine-tuned determination of target templates in complex forms where other comparable and relevant structural compounds could coexist. Implementation of quantum dots in MIPs improves their extraction features due to the presence of distinct functional sites. Quantum dots can be employed to modulate the size, detectability, and state of the imprinted materials, depending on the selected application. This review aims to summarize and illustrate the modern and innovative strategies based on the aggregation of MIPs with quantum dots. Quantum dot embedded MIPs can be exploited for simultaneous extraction, preconcentration, and detection of paclitaxel obtained from various sources.
Keywords: Molecularly imprinted polymer, quantum dots, MIP@QD sensor, nanocomposite, paclitaxel, taxol drug.
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DOI https://dx.doi.org/10.2174/2666145415666220928111532	Print ISSN 2666-1454
Publisher Name Bentham Science Publisher	Online ISSN 2666-1462
Current Materials Science

An Overview of Paclitaxel and Molecular Imprinted Polymers Capped with Quantum Dots as an Alternative Approach for Paclitaxel Extraction and Detection

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