Title:Adipose-derived Stem Cells: Potentials, Availability and Market Size in
Regenerative Medicine
Volume: 18
Issue: 3
Author(s): Adele Soltani, Maryam Moradi, Aida Rezaei Nejad, Shabnam Moradi, Ehsan Javandoost, Hojjatollah Nazari and Arefeh Jafarian*
Affiliation:
- Iranian Tissue Bank & Research Center, Gene, Cell & Tissue Institute, Tehran University of Medical Sciences, Tehran, Iran
Keywords:
ADSCs, market size, regenerative medicine, clinical trials, stromal-vascular fraction (SVF), vascular endothelial growth factor (VEGF).
Abstract:
Adipose-derived stem cells (ADSCs) have been described as one of the most potent and accessible
human adult stem cells which can be utilized in various therapeutic approaches. Due to the wide
variety of cytokines and GFs secreted by them, ADSCs can be used for controlled drug release. These
cells can be used for proliferation and differentiation of tissues regardless of survival conditions and immunologic
problems. Because of their ability to differentiate into various lineages, ADSCs can be used in
musculoskeletal problems, diabetes, heart diseases, obesity, neurologic and nephrogenic diseases, and
wound healing, as well as applications in regenerative medicine such as osteogenic, cartilage, tendon,
muscle, skin, CNS, cardiac and vascularization, as well as liver and even periodontal regeneration.
To maintain the highest viability and efficiency, companies that provide ADSCs should offer the best
product quality to gain market share and scientists need to acquire an understanding of sources where they
can find the best products available. Therefore, in this article, we have reviewed the available products,
companies and the market size currently available for ADSCs. Enormous effort has been made to list the
most important trials, products and companies currently existent in the field. To achieve better outcomes
in scientific research, there is the need to compare the products available and choose the best option according
to desired goals. Thus, this paper provides a valuable reference for those interested in the field of
ADSCs and their applications.
