Title:Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio as Biomarkers for Cardiovascular Surgery Procedures: A Literature Review
Volume: 16
Issue: 2
Author(s): Raffaele Serra*, Nicola Ielapi*, Noemi Licastro, Michele Provenzano, Michele Andreucci, Umberto Marcello Bracale, Federica Jiritano, Stefano de Franciscis, Pasquale Mastroroberto and Giuseppe Filiberto Serraino
Affiliation:
- Interuniversity Center of Phlebolymphology (CIFL), International Research and Educational Program in Clinical and Experimental Biotechnology” at the Department of Surgical and Medical Sciences University Magna Graecia of Catanzaro, Viale Europa 88100 Catanzaro,Italy
- Interuniversity Center of Phlebolymphology (CIFL), International Research and Educational Program in Clinical and Experimental Biotechnology” at the Department of Surgical and Medical Sciences University Magna Graecia of Catanzaro, Viale Europa 88100 Catanzaro,Italy
Keywords:
Neutrophil-to-lymphocyte ratio, NLR, platelet-to-lymphocyte ratio, PLR, cardiac surgery, vascular surgery, precision
medicine, outcome, surgery, endovascular.
Abstract:
Background: Neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio
(PLR) have been studied so far as prognostic factors of cardiovascular diseases. Their role interplayed
with endothelial inflammation has emerged as optimal predictors for major cardiovascular
disease events and prognostic factors for post-procedural outcomes.
Methods: A review of the current literature was undertaken to investigate the relationship between
NLR and PLR with percutaneous, cardiac surgery, and vascular surgery procedures.
Results: Our findings show that perioperative NLR and PLR levels are significantly correlated
with patient morbidity and mortality rates.
Conclusion: These biomarkers have several attractive characteristics, as they are inexpensive and
quickly available, and they can contribute to the early identification of patients at high risk for
periprocedural adverse events.
