This research article by Dr. Shweta Mittal et al. has been published in The Natural Product Journal, Volume 06, Issue 04, 2016
There is a continuous search for new, safe and relatively cheaper drugs with the advent of new diseases and increasing antibiotic resistance. Endophtyes having the potential to synthesize a wide array of bioactive compounds is an attractive alternative. They have the potential not only to synthesize plant metabolites but also a host of other natural products exhibiting a broad spectrum of structural and chemical diversities exhibiting biological activity and therefore can serve as lead molecule(s) for designing new drugs.
In the present study, an endophytic fungus Emericella sp., was isolated from its host plant Azadirachta indica growing in semi-arid regions of Rajasthan, India. The fungal biomass was subjected to organic extraction. Hexane, ethyl acetate, ethanol and methanol were used as solvents. Ethanolic extract from the biomass exhibited anticadidal activity.
For More Information about the article, please visit http://benthamscience.com/journals/the-natural-products-journal/volume/6/issue/3/page/188/