Open Access Articles ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

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  • 10th of 59 in Chemistry & Medicinal
  • 63rd of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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5 - Year: 3.508

Open Access Articles

Serotonin Receptor Binding Characteristics of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook

, 2017; 24: 1 - 10 (E-Pub Ahead of Print)

Yasushi Ikarashi, Kyoji Sekiguchi and Kazushige Mizoguchi.


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Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a Detoxifying Enzyme

, 2016; 23(35): 4027 - 4036

Maria Giulia Battelli, Letizia Polito, Massimo Bortolotti and Andrea Bolognesi.


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Osteoimmunology and Beyond

, 2016; 23(33): 3754 - 3774

Lia Ginaldi and Massimo De Martinis.


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Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain

, 2016; 23(26): 2908 - 2928

Katarzyna Popiolek-Barczyk and Joanna Mika.


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Why Antidiabetic Vanadium Complexes are Not in the Pipeline of “Big Pharma” Drug Research? A Critical Review

, 2016; 23(25): 2874 - 2891

Thomas Scior, Jose Antonio Guevara-Garcia, Quoc-Tuan Do, Philippe Bernard and Stefan Laufer.


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A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines

, 2016; 23(20): 2112 - 2131

Wojciech Filipiak, Pawel Mochalski, Anna Filipiak, Clemens Ager, Raquel Cumeras, Cristina E. Davis, Agapios Agapiou, Karl Unterkofler and Jakob Troppmair.


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Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

, 2016; 23(17): 1725 - 1755

Mieke De Buck, Mieke Gouwy, Ji Ming Wang, Jacques Van Snick, Ghislain Opdenakker, Sofie Struyf and Jo Van Damme.


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Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps

, 2016; 23(10): 1062 - 1081

Hannah Y. Mahmood, Shirin Jamshidi, J. Mark Sutton and Khondaker M Rahman.


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Food Proteins as Source of Opioid Peptides-A Review

, 2016; 23(9): 893 - 910

Swati Garg, Kulmira Nurgali and Vijay Kumar Mishra.


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Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

, 2016; 23(8): 792 - 815

Marisa Cabeza, Araceli Sánchez-Márquez, Mariana Garrido, Aylín Silva and Eugene Bratoeff.


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Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson’s Disease

, 2016; 23(7): 686 - 700

Ikuko Miyazaki and Masato Asanuma.


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Role of Tyrosine Isomers in Acute and Chronic Diseases Leading to Oxidative Stress - A Review

, 2016; 23(7): 667 - 685

Gergő A. Molnár, Szilárd Kun, Eszter Sélley, Melinda Kertész, Lívia Szélig, Csaba Csontos, Katalin Böddi, Lajos Bogár, Attila Miseta and István Wittmann.


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Eosinophils in Cancer: Favourable or Unfavourable?

, 2016; 23(7): 650 - 666

Samy Sakkal, Sarah Miller, Vasso Apostolopoulos and Kulmira Nurgali.


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A “Double-Edged” Scaffold: Antitumor Power within the Antibacterial Quinolone

, 2016; 23(6): 520 - 577

Gregory S. Bisacchi and Michael R Hale.


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Action of Nanoparticles on Platelet Activation and Plasmatic Coagulation

, 2016; 23(5): 408 - 430

Eleonore Fröhlich.


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Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging

, 2015; 22(31): 3631 - 3651

Gunter Almer, Harald Mangge, Andreas Zimmer and Ruth Prassl.


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Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review

, 2015; 22(21): 2580 - 2589

Rafael Simo, Stefania Ballarini, Jose Cunha-Vaz, Linong Ji, Hermann Haller, Paul Zimmet and Tien Y Wong.


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Bacteriophages and Phage-Derived Proteins – Application Approaches

, 2015; 22(14): 1757 - 1773

Zuzanna Drulis-Kawa, Grazyna Majkowska-Skrobek and Barbara Maciejewska.


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Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis

, 2015; 22(7): 799 - 818

Ralf Hausmann, Achim Kless and Gunther Schmalzing.


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Recent Development of Multifunctional Agents as Potential Drug Candidates for the Treatment of Alzheimer’s Disease

, 2015; 22(3): 373 - 404

Natalia Guzior, Anna Wi eckowska, Dawid Panek and Barbara Malawska.


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Novel Strategies for Preventing Diabetes and Obesity Complications with Natural Polyphenols

, 2015; 22(1): 150 - 164

C. Carpene, S. Gomez-Zorita, S. Deleruyelle and MA Carpene.


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Interactions Between Nanosized Materials and the Brain

, 2014; 21(37): 4200 - 4214

M. Simko and Mats-Olof Mattsson.


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A Common Molecular Motif Characterizes Extracellular Allosteric Enhancers of GPCR Aminergic Receptors and Suggests Enhancer Mechanism of Action

, 2014; 21(32): 3673 - 3686

Robert Root-Bernstein and Patrick F Dillon.


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Atrial Natriuretic Peptide: A Magic Bullet for Cancer Therapy Targeting Wnt Signaling and Cellular pH Regulators

, 2014; 21(21): 2401 - 2409

A. Serafino and P Pierimarchi.


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In Vitro and In Vivo Models for Analysis of Resistance to Anticancer Molecular Therapies

, 2014; 21(14): 1595 - 1606

Roberta Rosa, Francesca Monteleone, Nicola Zambrano and Roberto Bianco.


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Histopathological Determinants of Tumor Resistance: A Special Look to the Immunohistochemical Expression of Carbonic Anhydrase IX in Human Cancers

, 2014; 21(14): 1569 - 1582

G. Ilardi, N. Zambrano, F. Merolla, M. Siano, S. Varricchio, M. Vecchione, G. De Rosa, M. Mascolo and S Staibano.


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Exogenous Hormonal Regulation in Breast Cancer Cells by Phytoestrogens and Endocrine Disruptors

, 2014; 21(9): 1129 - 1145

A. Albini, C. Rosano, G. Angelini, A. Amaro, A.I. Esposito, S. Maramotti, D.M. Noonan and U Pfeffer.


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Pathophysiogenesis of Mesial Temporal Lobe Epilepsy: Is Prevention of Damage Antiepileptogenic?

, 2014; 21(6): 663 - 688

G. Curia, C. Lucchi, J. Vinet, F. Gualtieri, C. Marinelli, A. Torsello, L. Costantino and G Biagini.


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Phytoestrogens in Postmenopause: The State of the Art from a Chemical, Pharmacological and Regulatory Perspective

, 2014; 21(4): 417 - 436

Elisabetta Poluzzi, Carlo Piccinni, Emanuel Raschi, Angela Rampa, Maurizio Recanatini and Fabrizio De Ponti.


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An Update on Autoinflammatory Diseases

, 2014; 21(3): 261 - 269

F. Ciccarelli, M. De Martinis and L Ginaldi.


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An Up-date of Olive Oil Phenols in Inflammation and Cancer: Molecular Mechanisms and Clinical Implications

, 2013; 20(37): 4758 - 4776

A. Cárdeno, M. Sánchez-Hidalgo and C Alarcón-de-la-Lastra.


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Reduction of Breast Cancer Relapses with Perioperative Non-Steroidal Anti-Inflammatory Drugs: New Findings and a Review

, 2013; 20(33): 4163 - 4176

Michael Retsky, Romano Demicheli, William J.M. Hrushesky, Patrice Forget, Marc De Kock, Isaac Gukas, Rick A Rogers, Michael Baum, Vikas Sukhatme and Jayant S Vaidya.


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Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction

, 2013; 20(32): 4050 - 4059

S. L. Martin, T. M. Hardy and T O Tollefsbol.


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Neuroprotective Properties of Curcumin in Alzheimer’s Disease – Merits and Limitations

, 2013; 20(32): 3955 - 3985

Dawn Chin, Patricia Huebbe, Kathrin Pallauf and Gerald Rimbach.


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Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics

, 2013; 20(31): 3855 - 3871

Tomo Yonezawa, Riho Kurata, Kaori Yoshida, Masanori A. Murayama, Xiaofeng Cui and Akihiko Hasegawa.


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Tuberculosis Clinical Trial Update and the Current Anti-Tuberculosis Drug Portfolio

, 2013; 20(30): 3785 - 3796

Juan Carlos Palomino and Anandi Martin.


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A Novel Promising Therapeutic Option Against Hepatitis C Virus: An Oral Nucleotide NS5B Polymerase Inhibitor Sofosbuvir

, 2013; 20(30): 3733 - 3742

I. Gentile, F. Borgia, A. R. Buonomo, G. Castaldo and G Borgia.


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Reactive Oxygen Species in Cancer Biology and Anticancer Therapy

, 2013; 20(30): 3677 - 3692

Y. Yang, S. Karakhanova, J. Werner and A V Bazhin.


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MicroRNAs and Cancer Therapy – From Bystanders to Major Players

, 2013; 20(29): 3561 - 3573

Cornelia Braicu, George A. Calin and Ioana Berindan-Neagoe.


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Neurodegeneration in the Pathogenesis of Diabetic Retinopathy: Molecular Mechanisms and Therapeutic Implications

, 2013; 20(26): 3241 - 3250

Maxwell S. Stem and Thomas W Gardner.


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Mitochondria Damage in the Pathogenesis of Diabetic Retinopathy and in the Metabolic Memory Associated with its Continued Progression

, 2013; 20(26): 3226 - 3233

Renu A Kowluru.


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Calpains: Potential Targets for Alternative Chemotherapeutic Intervention Against Human Pathogenic Trypanosomatids

, 2013; 20(25): 3174 - 3185

M. H. Branquinha, F. A. Marinho, L. S. Sangenito, S. S.C. Oliveira, K. C. Goncalves, V. Ennes-Vidal, C. M. d’Avila-Levy and A LS Santos.


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Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy

, 2013; 20(25): 3116 - 3133

L. O. Santos, A. S. Garcia-Gomes, M. Catanho, C. L. Sodre, A. L.S. Santos, M. H. Branquinha and C M d’Avila-Levy.


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Parasite Prolyl Oligopeptidases and the Challenge of Designing Chemotherapeuticals for Chagas Disease, Leishmaniasis and African Trypanosomiasis

, 2013; 20(25): 3103 - 3115

I. M.D. Bastos, F. N. Motta, P. Grellier and J M Santana.


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Synthetic and Natural Protease Inhibitors Provide Insights into Parasite Development, Virulence and Pathogenesis

, 2013; 20(25): 3078 - 3102

A. A. Rascon and J H McKerrow.


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n-3 Fatty Acids: Role in Neurogenesis and Neuroplasticity

, 2013; 20(24): 2953 - 2963

R. Crupi, A. Marino and S Cuzzocrea.


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An Overview on Natural Polysaccharides with Antioxidant Properties

, 2013; 20(23): 2899 - 2913

H. Wang, Y. M. Liu, Z. M. Qi, S. Y. Wang, S. X. Liu, X. Li, H. J. Wang and X C Xia.


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Virtual Screening Strategies in Drug Discovery: A Critical Review

, 2013; 20(23): 2839 - 2860

A. Lavecchia and C Di Giovanni.


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Trypanosomatidae Diseases: From the Current Therapy to the Efficacious Role of Trypanothione Reductase in Drug Discovery

, 2013; 20(21): 2673 - 2696

L.S.C. Bernardes, C.L. Zani and I Carvalho.


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Flavonoids in Atherosclerosis: An Overview of Their Mechanisms of Action

, 2013; 20(21): 2641 - 2660

G. Siasos, D. Tousoulis, V. Tsigkou, E. Kokkou, E. Oikonomou, M. Vavuranakis, E.K. Basdra, A.G. Papavassiliou and C Stefanadis.


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Bioavailability of Quercetin: Problems and Promises

, 2013; 20(20): 2572 - 2582

X. Cai, Z. Fang, J. Dou, A. Yu and G Zhai.


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Clinical and Marketed Proteasome Inhibitors for Cancer Treatment

, 2013; 20(20): 2537 - 2551

Jiankang Zhang, Peng Wu and Yongzhou Hu.


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Piroxicam-β-Cyclodextrin: A GI Safer Piroxicam

, 2013; 20(19): 2415 - 2437

C Scarpignato.


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Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery

, 2013; 20(18): 2374 - 2388

Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A Inui.


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1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome

, 2013; 20(18): 2351 - 2362

X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and BO Villoutreix.


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Luminescent Silica Nanoparticles for Cancer Diagnosis

, 2013; 20(17): 2195 - 2211

W. Arap, R. Pasqualini, M. Montalti, L. Petrizza, L. Prodi, E. Rampazzo, N. Zaccheroni and S Marchio.


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Computational Peptidology: A New and Promising Approach to Therapeutic Peptide Design

, 2013; 20(15): 1985 - 1996

P. Zhou, C. Wang, Y. Ren, C. Yang and F Tian.


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Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells

, 2013; 20(15): 1923 - 1945

Giuliana Cassinelli, Valentina Zuco, Laura Gatti, Cinzia Lanzi, Nadia Zaffaroni, Diego Colombo and Paola Perego.


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Histone Deacetylase Inhibitors: An Attractive Strategy for Cancer Therapy

, 2013; 20(14): 1858 - 1886

Jiyang Li, Guangqiang Li and Wenqing Xu.


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RNAi in Clinical Studies

, 2013; 20(14): 1801 - 1816

P. Kubowicz, D. Zelaszczyk and E Pekala.


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Multi-Target Compounds Acting in the Central Nervous System Designed From Natural Products

, 2013; 20(13): 1673 - 1685

X. Chen and M Decker.


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Rationally Designed Multi-Targeted Agents Against Neurodegenerative Diseases

, 2013; 20(13): 1662 - 1672

W. J. Geldenhuys and C J Van der Schyf.


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The Economics of Polypharmacology: Fixed Dose Combinations and Drug Cocktails

, 2013; 20(13): 1635 - 1638

A I Wertheimer.


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Camptothecin Resistance in Cancer: Insights into the Molecular Mechanisms of a DNA-Damaging Drug

, 2013; 20(12): 1541 - 1565

G. L. Beretta, L. Gatti, P. Perego and N Zaffaroni.


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Long-Acting Beta-Agonists and their Association with Inhaled Corticosteroids in COPD

, 2013; 20(12): 1477 - 1495

L. Fuso, N. Mores, S. Valente, M. Malerba and P Montuschi.


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Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

, 2013; 20(10): 1323 - 1331

S. Bo, G. Ciccone, A. Castiglione, R. Gambino, F. De Michieli, P. Villois, M. Durazzo, P. Cavallo-Perin and M Cassader.


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Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia

, 2013; 20(10): 1306 - 1312

L. Minutoli, A. Bitto, F. Squadrito, H. Marini, N. Irrera, G. Morgia, A. Passantino and D Altavilla.


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Ion Channels as Drug Targets in Central Nervous System Disorders

, 2013; 20(10): 1241 - 1285

A. M. Waszkielewicz, A. Gunia, N. Szkaradek, K. Sloczynska, S. Krupinska and H Marona.


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Plant Metabolomics: From Holistic Data to Relevant Biomarkers

, 2013; 20(8): 1056 - 1090

Jean-Luc Wolfender, Serge Rudaz, Young Hae Choi and Hye Kyong Kim.


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From Resveratrol to Its Derivatives: New Sources of Natural Antioxidant

, 2013; 20(8): 1005 - 1017

Shan He and Xiaojun Yan.


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Antimicrobial Plant Metabolites: Structural Diversity and Mechanism of Action

, 2013; 20(7): 932 - 952

N.S. Radulovic, P.D. Blagojevic, Z.Z. Stojanovic-Radic and NM Stojanovic.


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The Pentacyclic Triterpenoids in Herbal Medicines and Their Pharmacological Activities in Diabetes and Diabetic Complications

, 2013; 20(7): 908 - 931

A. Alqahtani, K. Hamid, A. Kam, K.H. Wong, Z. Abdelhak, V. Razmovski-Naumovski, K. Chan, K.M. Li, P.W. Groundwater and GQ Li.


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Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles

, 2013; 20(6): 794 - 814

Martine Demeunynck and Isabelle Baussanne.


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Glyconanoparticles-An Update

, 2013; 20(6): 782 - 788

Gangliang Huang.


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Honey as a Source of Dietary Antioxidants: Structures, Bioavailability and Evidence of Protective Effects Against Human Chronic Diseases

, 2013; 20(5): 621 - 638

Josè M. Alvarez-Suarez, Francesca Giampieri and Maurizio Battino.


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Treatment of Estrogen Receptor-Positive Breast Cancer

, 2013; 20(5): 596 - 604

F. Lumachi, A. Brunello, M. Maruzzo, U. Basso and S MM Basso.


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The Current Status of Sweat Testing For Drugs of Abuse: A Review

, 2013; 20(4): 545 - 561

N. De Giovanni and N Fucci.


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New Chemotherapeutic Strategies Against Malaria, Leishmaniasis and Trypanosomiases

, 2013; 20(4): 502 - 526

M. Zucca, S. Scutera and D Savoia.


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Do Subjects at Clinical High Risk for Psychosis Differ from those with a Genetic High Risk? - A Systematic Review of Structural and Functional Brain Abnormalities

, 2013; 20(3): 467 - 481

R. Smieskova, J. Marmy, A. Schmidt, K. Bendfeldt, A. Riecher-Rossler, M. Walter, U. E. Lang and S Borgwardt.


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Volumetric Changes in the Basal Ganglia After Antipsychotic Monotherapy: A Systematic Review

, 2013; 20(3): 438 - 447

B. H. Ebdrup, H. Norbak, S. Borgwardt and B Glenthoj.


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Transcranial Brain Stimulation in Schizophrenia: Targeting Cortical Excitability, Connectivity and Plasticity

, 2013; 20(3): 405 - 413

A. Hasan, P. Falkai and T Wobrock.


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Abnormal Striatal Dopamine Transmission in Schizophrenia

, 2013; 20(3): 397 - 404

Jerome Brunelin, Shirley Fecteau and Marie-Francoise Suaud-Chagny.


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Serotonin Receptors of Type 6 (5-HT6): From Neuroscience to Clinical Pharmacology

, 2013; 20(3): 371 - 377

Donatella Marazziti, Stefano Baroni, Franco Borsini, Michela Picchetti, Elena Vatteroni, Valentina Falaschi and Mario Catena-Dell’Osso.


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Metabolomics Analysis for Biomarker Discovery: Advances and Challenges

, 2013; 20(2): 257 - 271

M.S. Monteiro, M. Carvalho, M.L. Bastos and P Guedes de Pinho.


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Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment

, 2013; 20(2): 167 - 185

C. Zagni, U. Chiacchio and A Rescifina.


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Polymer Nanoparticles - A Novel Strategy for Administration of Paclitaxel in Cancer Chemotherapy

, 2012; 19(36): 6207 - 6213

G. Deepa, N. Ashwanikumar, J. J. Pillai and G SV Kumar.


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Recent Lipase-Catalyzed Hydrolytic Approaches to Pharmacologically Important β-and λ-Amino Acids

, 2012; 19(36): 6178 - 6187

E. Forro and F Fulop.


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Alveolar Epithelial Stem and Progenitor Cells: Emerging Evidence for their Role in Lung Regeneration

, 2012; 19(35): 6003 - 6008

A. M. Hoffman and E P Ingenito.


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Stem Cells, Self-Renewal and Cancer of the Gastric Epithelium

, 2012; 19(35): 5975 - 5983

Werner Hoffmann.


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Store-Dependent Ca2+ Entry in Endothelial Progenitor Cells As a Perspective Tool to Enhance Cell-Based Therapy and Adverse Tumour Vascularization

, 2012; 19(34): 5802 - 5818

F. Moccia, S. Dragoni, F. Lodola, E. Bonetti, C. Bottino, G. Guerra, U. Laforenza, V. Rosti and F Tanzi.


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Polarization of Calcium Signaling and Fluid Secretion in Salivary Gland Cells

, 2012; 19(34): 5774 - 5781

I S Ambudkar.


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Signal Transduction Pathways of the Epidermal Growth Factor Receptor in Colorectal Cancer and their Inhibition by Small Molecules

, 2012; 19(33): 5735 - 5744

T Efferth.


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Contribution of Oxidative Metabolism to Cocaine-Induced Liver and Kidney Damage

, 2012; 19(33): 5601 - 5606

M.J. Valente, F. Carvalho, M.d.L. Bastos, P.G. de Pinho and M Carvalho.


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Adiponectin: Key Player in the Adipose Tissue-Liver Crosstalk

, 2012; 19(32): 5467 - 5473

A. R. Moschen, V. Wieser and H Tilg.


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Protective Role of Adiponectin in Cardiovascular Disease

, 2012; 19(32): 5459 - 5466

R. Shibata, T. Murohara and N Ouchi.


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A Targeted Therapy for Protein and Lipid Kinases in Chronic Lymphocytic Leukemia

, 2012; 19(31): 5294 - 5318

P. Robak and T Robak.


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Immunoliposomes

, 2012; 19(31): 5239 - 5277

E. Paszko and MO Senge.


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Glutamate Transporter 1: Target for the Treatment of Alcohol Dependence

, 2012; 19(30): 5148 - 5156

P.S.S. Rao and Y Sari.


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Fragment Based Drug Design: From Experimental to Computational Approaches

, 2012; 19(30): 5128 - 5147

A. Kumar, A. Voet and KYJ Zhang.


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From Metallodrugs to Metallodendrimers for Nanotherapy in Oncology: A Concise Overview

, 2012; 19(29): 4995 - 5010

S. El Kazzouli, N. El Brahmi, S. Mignani, M. Bousmina, M. Zablocka and J -P Majoral.


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Fluorescent Dendrimers As Sensors for Biologically Important Metal Cations

, 2012; 19(29): 4976 - 4983

I. Grabchev, D. Staneva and R Betcheva.


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Role of Oxidative Stress and Molecular Changes in Liver Fibrosis: A Review

, 2012; 19(28): 4850 - 4860

V. Sanchez-Valle, N. C. Chavez-Tapia, M. Uribe and N Mendez-Sanchez.


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Recent Advances in Receptor-Targeted Fluorescent Probes for In Vivo Cancer Imaging

, 2012; 19(28): 4742 - 4758

M. Bai and D J Bornhop.


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New Strategies Against Prostate Cancer – Pt(II)-Based Chemotherapy

, 2012; 19(27): 4678 - 4687

C. S. Matos, A. L.M.B. de Carvalho, R. P. Lopes and M PM Marques.


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Review Metabolomics: A New Approach to Drug Delivery in Perinatology

, 2012; 19(27): 4654 - 4661

L. Atzori, J. L. Griffin, A. Noto and V Fanos.


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Peptides As Therapeutics with Enhanced Bioactivity

, 2012; 19(26): 4451 - 4461

D. Goodwin, P. Simerska and I Toth.


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Biology and Clinical Management of Myeloproliferative Neoplasms and Development of the JAK Inhibitor Ruxolitinib

, 2012; 19(26): 4399 - 4413

J. Mascarenhas, T. I. Mughal and S Verstovsek.


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Insights into Targeting Colon Cancer Cell Fate at the Level of Proteoglycans / Glycosaminoglycans

, 2012; 19(25): 4247 - 4258

D. Nikitovic, G. Chatzinikolaou, J. Tsiaoussis, A. Tsatsakis, N. K. Karamanos and G N Tzanakakis.


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The Synergistic Effects of DNA-Targeted Chemotherapeutics and Histone Deacetylase Inhibitors As Therapeutic Strategies for Cancer Treatment

, 2012; 19(25): 4218 - 4238

M. Stiborova, T. Eckschlager, J. Poljakova, J. Hrabeta, V. Adam, R. Kizek and E Frei.


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Physicochemical Strategies for Inhibition of Amyloid Fibril Formation: An Overview of Recent Advances

, 2012; 19(24): 4157 - 4174

R. Liu, R. Su, M. Liang, R. Huang, M. Wang, W. Qi and Z He.


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Chromogranin-A: A Multifaceted Cardiovascular Role in Health and Disease

, 2012; 19(24): 4042 - 4050

T. Angelone, R. Mazza and M C Cerra.


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Glutathione-Related Factors and Oxidative Stress in Autism, A Review

, 2012; 19(23): 4000 - 4005

A. Ghanizadeh, S. Akhondzadeh, M. Hormozi, A. Makarem, M. Abotorabi-Zarchi and A Firoozabadi.


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Role of PARP Inhibitors in Cancer Biology and Therapy

, 2012; 19(23): 3907 - 3921

D. Davar, J. H. Beumer, L. Hamieh and H Tawbi.


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Structure and Ligand Based Drug Design Strategies in the Development of Novel 5- LOX Inhibitors

, 2012; 19(22): 3763 - 3778

Polamarasetty Aparoy, Kakularam Kumar Reddy and Pallu Reddanna.


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Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

, 2012; 19(22): 3748 - 3762

D. A. Altomare and A R Khaled.


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Combinatorial Nanoparticles for Cancer Diagnosis and Therapy

, 2012; 19(22): 3714 - 3721

A. Mukerjee, A. P. Ranjan and J K Vishwanatha.


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Survivin as a Prognostic/Predictive Marker and Molecular Target in Cancer Therapy

, 2012; 19(22): 3679 - 3688

F. Rodel, T. Sprenger, B. Kaina, T. Liersch, C. Rodel, S. Fulda and S Hehlgans.


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Antimicrobial and Biofilm Inhibiting Diketopiperazines

, 2012; 19(21): 3564 - 3577

M. P. de Carvalho and W-R Abraham.


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Recent Progress in the Development of Agonists and Antagonists for Melatonin Receptors

, 2012; 19(21): 3532 - 3549

D P Zlotos.


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Designed Multiple Ligands: Basic Research vs Clinical Outcomes

, 2012; 19(20): 3353 - 3387

L. Costantino and D Barlocco.


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Radiolabelled Agents for PET Imaging of Tumor Hypoxia

, 2012; 19(20): 3282 - 3289

H. Kurihara, N. Honda, Y. Kono and Y Arai.


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Drug Targeting to Cancer by Nanoparticles Surface Functionalized with Special Biomolecules

, 2012; 19(19): 3188 - 3195

M. A. Holgado, L. Martin-Banderas, J. Alvarez-Fuentes, M. Fernandez-Arevalo and J L Arias.


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Drug-Loaded Nanocarriers: Passive Targeting and Crossing of Biological Barriers

, 2012; 19(19): 3070 - 3102

J. M. Rabanel, V. Aoun, I. Elkin, M. Mokhtar and P Hildgen.


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Recent Progress and Future Potential for Metal Complexes as Anticancer Drugs Targeting G-quadruplex DNA

, 2012; 19(18): 2957 - 2975

J. Zhang, F. Zhang, H. Li, C. Liu, J. Xia, L. Ma, W. Chu, Z. Zhang, C. Chen, S. Li and S Wang.


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Protocatechuic Acid and Human Disease Prevention: Biological Activities and Molecular Mechanisms

, 2012; 19(18): 2901 - 2917

R. Masella, C. Santangelo, M. D’Archivio, G. LiVolti, C. Giovannini and F Galvano.


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Chelating Agents for the Treatment of Systemic Iron Overload

, 2012; 19(17): 2816 - 2827

Y. Ma, T. Zhou, X. Kong and R C Hider.


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Iron Chelators for the Treatment of Cancer

, 2012; 19(17): 2689 - 2702

Y. Yu, E. Gutierrez, Z. Kovacevic, F. Saletta, P. Obeidy, Y. Suryo Rahmanto and D R Richardson.


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The Role of microRNAs in Cardiovascular Disease

, 2012; 19(16): 2605 - 2610

N. Papageorgiou, D. Tousoulis, E. Androulakis, G. Siasos, A. Briasoulis, G. Vogiatzi, A.-M. Kampoli, E. Tsiamis, C. Tentolouris and C Stefanadis.


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